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Text version   RSS   Subscribe   Unsubscribe   Archive   Media Kit January 24, 2018

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SLAS Ignite: Find, Fund and Formalize Research Partnerships at SLAS2018
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Life sciences professionals and business development dealmakers from all walks of industry, academia and government have a new hub at SLAS2018 — SLAS Ignite, a series of programs that foster scientific innovation through collaboration. One aspect of SLAS Ignite, the SLAS Ignite Partnership Program, facilitates partner connections through a module in the official SLAS2018 Conference App. Participants complete a personalized profile and then search other users for prospective collaboration opportunities. If there's a mutual interest, prospective partners are assigned a time to meet at the SLAS Ignite Partnership Lounge in the SLAS2018 Exhibition. Learn more about the SLAS Ignite Partnership Program.

In the meantime, new SLAS Ignite Academic Theater Presentations help six selected researchers tap into the experience, insights and capabilities of peers and complementary organizations. Presentations, kindled by moderator Cathy Tralau-Stewart, Ph.D., of the University of California, San Francisco (UCSF), launch in the SLAS2018 Exhibition Theater. See the SLAS2018 Event Scheduler for more information about these presentations:

Monday, February 5, 2018, 1-2 p.m., Exhibition Theater, Exhibition Halls B&C Tuesday, February 6, 2018, 1-2 p.m., Exhibition Theater, Exhibition Halls B&C
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NEW and FREE at SLAS Technology: Fast and Label-Free Isolation of Circulating Tumor Cells from Blood
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The work of 2017 SLAS Innovation Award-winning author Elodie Sollier-Christen headlines the February 2018 issue of SLAS Technology. Available for free for a limited time, the article describes a new platform that could change the way cancer is diagnosed and treated by automating the isolation of circulating tumor cells (CTCs) directly from cancer patient blood. Sollier-Christen’s research provides unique insight into the development of a commercial system that has the potential to change the standard of care in cancer diagnosis and treatment. The VTX-1 Liquid Biopsy System was designed to automate the isolation of clinically relevant CTC populations, making the CTCs available for easy analysis by a variety of techniques. In this publication, the transition from a cutting-edge microfluidic innovation in the research setting to a commercial, automated system for isolating CTCs directly from whole blood is outlined. Image by Marc Lim. More


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SLAS2018 Short Course Spotlight: Liquid Handling Essentials
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Become a proficient problem-solver by participating in the Liquid Handling Essentials Short Course on Sunday, Feb. 4 at SLAS2018. This one-day course helps new or beginning users quickly become well informed in the basic principles of liquid handling and troubleshooting pipetting performance issues. A balance of both discussions and hands-on activities focus on applying key practices in live systems and measuring performance metrics. Add short courses to your conference registration by using this Online form. For a complete list and schedule of SLAS2018 Short Courses and course fees, please click here. More


SLAS ELN Reports: Use Soft Skills to Sell Your Hard-Earned Life Sciences Technical Expertise
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If you're a student or early career professional in the life sciences, chances are you have focused on education and building your technical expertise in the lab. You may not have had an opportunity to think about the soft skills — communication, teamwork and leadership, to name a few — that demonstrate intangible abilities in a tangible way. SLAS2018 Career Connections speakers, Marquita M. Qualls, Ph.D. (Entropia Consulting, Washington, DC), and Thomas Kost, Ph.D., share how these skills factor into who gets the job, leads the team, makes the presentation and secures that important promotion in this SLAS Electronic Laboratory Neighborhood (SLAS ELN) article. More




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Products on Parade at SLAS2018
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Bookmark the SLAS2018 New Products Announcements page to monitor the fast-growing list of products to be unveiled at SLAS2018 in San Diego. The latest additions to the list of now more than 30 products include: Coastal Genomics Inc. (Burnaby, BC, Canada) introducing LightBench; BellBrook Labs (Madison, WI) presenting AptaFluor SAH Methyltransferase Assay; and StemoniX (Maple Grove, MN; an SLAS Innovation AveNEW participant at SLAS2017) rolling out the microBrain 3D Assay Ready 384-Well Plates. SLAS2018 exhibitors: Click here to add your new product launch to the list! More


Publons: A New Benefit for SLAS Journal Manuscript Reviewers
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Publons functionality is now integrated into the SLAS Discovery and SLAS Technology manuscript submission management systems to ensure reviewers receive proper credit for their contributions to the scholarly literature. Every year, hundreds of proven experts thoughtfully assess SLAS journal manuscript submissions. These volunteers often go unnoticed because they work behind the scenes, but they are absolutely mission-critical to the publication of first class science. Publons allows the scientific community to formally recognize their contributions in a way that can be validated and added to their CVs while still maintaining confidentiality. Current and prospective reviewers also are encouraged to complete free ACS Reviewer Lab training. More




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Nonviral Gene Therapy Platform Delivers CRISPR/Cas9 to Tumors
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A platform for gene delivery and tumor therapy has been introduced that harnesses the power of the CRISPR/Cas9 gene-editing system. At the same time, the platform avoids some of the drawbacks of the CRISPR/Cas9 system. Specifically, the platform can cope with CRISPR/Cas9's sheer bulk, achieving highly efficient and targeted delivery to tumor cells. More


Scientists Discover 'Legos of Life'
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Rutgers scientists have found the "Legos of life" — four core chemical structures that can be stacked together to build the myriad proteins inside every organism — after smashing and dissecting nearly 10,000 proteins to understand their component parts. The four building blocks make energy available for humans and all other living organisms, according to a study published online in the Proceedings of the National Academy of Sciences. More




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Cryo-EM Reveals Critical Protein-Modifying Complex and Potential Drug Target
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Scientists have revealed the atomic-level structure of a molecular complex responsible for modifying proteins, possibly paving the way for the development of new medications for cancer and a host of other diseases. The complex, known as OST, is a key player in protein glycosylation, a wide-spread cell process that is intimately linked to numerous functions in the human body. More


Learning Opens the Genome
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A new bioinformatics strategy called DEScan has enabled researchers to identify genomic regions that undergo changes in chromatin accessibility in response to learning, according to a report in Science Signaling. Examining hippocampal neurons from mice before and after fear conditioning revealed widespread changes in chromatin conformation, mainly toward a more open structure. More




Cooperative Al-H Bond Activation in DIBAL-H: Catalytic Generation of an Alumenium-Ion-Like Lewis Acid for Hydrodefluorinative Friedel-Crafts Alkylation
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The Ru–S bond in Ohki–Tatsumi complexes breaks oligomeric DIBAL-H structures into their more reactive monomer. That deaggregation is coupled to heterolytic Al–H bond activation at the Ru–S bond, formally splitting the Al–H linkage into hydride and an alumenium ion. The molecular structure of these Lewis pairs was established crystallographically, revealing an additional Ru–Al interaction next to the Ru–H and Al–S bonds. More


Cells Lacking Nuclei Struggle to Move in 3-D Environments
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University of North Carolina Lineberger Comprehensive Cancer Center researchers have revealed new details of how the physical properties of the nucleus influence how cells can move around different environments — such as "soft" tissue like brain and fat, or "stiff" tissue like cartilage or bone. The researchers removed the nucleus from cells or disconnected them from the cell's structural scaffolding known as the "cytoskeleton." More


3-D-Printed Reactors Construct Complex Small Molecules
Chemical & Engineering News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Constructing complex chemicals could one day be as easy as building an Ikea bookshelf, if a synthesis approach developed by chemists at the University of Glasgow catches on. Instead of relying on a hex key as the central tool in the assembly process, molecule makers would use a three-dimensional printer. Leroy Cronin and colleagues report a chemical manufacturing process that uses customized, 3-D-printed, sealed reactors that users load with chemicals according to simple instructions. More


Activated Muscle Growth Inhibitor Could Treat ALS
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Researchers at the University of Cincinnati College of Medicine are part of an international team that has identified how the inactive or latent form of GDF8, a signaling protein also known as myostatin and responsible for limiting muscle, is activated. That knowledge could someday help in finding a better treatment to improve muscle function in diseases such as muscular dystrophy, amyotrophic lateral sclerosis or Lou Gehrig's disease, and cancer cachexia, a muscle wasting condition. More


Career


Principal Scientist In Vivo Pharmacology Neuroscience
Merck
US - PA - West Point

Supplier Development & Process Leader - Vancouver
LivaNova
CA - BC - Burnaby

Chair, Department of Epidemiology and Health Services Research
Geisinger Health System
US - PA - Danville

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