This message contains images. If you don't see images, click here to view. Advertise in this news brief. Advertisement Text version   RSS   Subscribe   Unsubscribe   Archive   Media Kit February 10, 2016 SLAS.org    SLAS2016    SLAS2017    Moving? New job? Let SLAS know.       Advertisement Advertisement Advertisement Advertisement Advertisement Advertisement   Advertisement Select SLAS2016 Presentations Now Available On Demand SLAS    Share    Seven podium presentations were recorded at SLAS2016 and are now available on-demand by full conference registrants (until March 31, 2016) and dues-paying SLAS members. HT-MALDI-MS as a Complete Label-Free Drug Discovery Platform: From Target Characterization through High-Throughput Screening to Hit Follow Up (Scott Busby, Novartis Institutes for Biomedical Research, USA) Development of a Platform to Enable Fully Automated Cross-Titration Experiments (Jason Cassaday, Merck, USA) Identifying Druggable Cells: Automated Methods for High-Content Single-Cell Screening (Tiffany Chen, Cytobank, Inc. and Stanford University, USA) High-Throughput Screening of Metagenomic DNA Libraries (Louis Cohen, Icahn School of Medicine at Mount Sinai, USA) Genome Engineering with Zinc Finger Nucleases (Ed Rebar, Sangamo BioSciences, USA) Droplet Microfluidics: Amphiphilic Nanoparticles as Droplet Stabilizers for High-Fidelity and Ultrahigh-Throughput Droplet Assays (Sindy Tang, Stanford University, USA) Drug-Target Residence Time: Target Engagement, Target Vulnerability and Predictions of in Vivo Drug Activity (Peter Tonge, Stony Brook University, USA) More Advertisement SLAS Sets New Attendance Record at SLAS2016 SLAS    Share    SLAS welcomed a record-setting 6,293 participants from 34 countries to SLAS2016, the Society's Fifth Annual International Conference and Exhibition, which convened Jan. 23-27 in San Diego, CA. "As a Society, we're exceptionally pleased with the turnout, high quality of programming and tremendous professional networking that took place at SLAS2016," says SLAS President Richard Eglen. "That we established a new benchmark for participation is secondary to the highly positive feedback we have received from attendees, exhibitors and presenters as to how much they enjoyed the experience and the value they derived from attending. It's obvious that SLAS is filling an important niche for life sciences professionals and students." Mark your calendar now for SLAS2017, Feb. 4-8, Washington, DC. More Advertisement Meet the experts that can empower your lab. Free at JBS Online: Characterization of Differentiated SH-SY5Y as Neuronal Screening Model Reveals Increased Oxidative Vulnerability SLAS    Share    A team from the Luxembourg Centre for Systems Biomedicine says, "the immortalized and proliferative cell line SH-SY5Y is one of the most commonly used cell lines in neuroscience and neuroblastoma research. However, undifferentiated SH-SY5Y cells share few properties with mature neurons. In this study, we present an optimized neuronal differentiation protocol for SH-SY5Y that requires only two work steps and six days. After differentiation, the cells present increased levels of ATP and plasma membrane activity but reduced expression of energetic stress response genes." More From the SLAS President: SLAS Never Ceases to Amaze Me SLAS     Share    "As I write this, my head is still spinning from an invigorating and exciting SLAS2016 in San Diego," says SLAS President Richard Eglen in his first column in the SLAS Electronic Laboratory Neighborhood e-zine. "The energy and enthusiasm were palpable everywhere I looked; morning, noon and night. It was so impressive and gratifying to see nearly 6,300 life sciences professionals from 34 countries engaged in the science, the educational program and, as importantly, with each other. SLAS never ceases to amaze me with its openness and friendly sense of collegiality, and our diversity within such a uniquely focused scope truly is one of our greatest strengths as an organization." More Advertisement ROBOTIC SAMPLE HANDLING SYSTEMS Experience accelerated research and increased throughput with robotic sample loading systems and accessories from Prior Scientific. Select from our automated slide and well plate loaders, LED and metal halide fluorescence illuminators, Piezo Z stages, motorized filter wheels, high speed shutters as well as custom and OEM electromechanical and optical systems. Vote by Feb. 19 for Your Favorite Finalist in the JALA & JBS Art of Science Contest SLAS    Share    Ten finalists have been selected, and now it's up to the SLAS community to decide which one will receive the grand prize of a $500 Amazon gift card for the most mesmerizing scientific image. Vote for your favorite finalist by 5:00 p.m. U.S. Eastern time on Feb. 19, 2016. SLAS members and nonmembers are welcome to vote. There are entries from Australia, China, Italy, New Zealand, Switzerland, United Kingdom and United States. More Advertisement JALA Special Issue Call for Papers: Micro and Nanotechnologies for Quantitative Biology and Medicine SLAS    Share    A quantitative approach to biology and medicine is essential for understanding how biological systems respond to dynamically changing environments and for developing new therapeutic strategies to combat disease. Recent advancements in micro and nanotechnologies have revolutionized biomedical research in engineering controlled interfaces to biological systems. These quantitative enabling technologies hold great potential to accelerate early diagnosis and treatment of disease. JALA Guest Editor Somin Eunice Lee of the University of Michigan invites abstract submissions for the special issue by April 1, 2016 that highlight and explore diverse quantitative approaches and their applications. More Advertisement AUTOMATED, REPRODUCIBLE PHOSPHOPEPTIDE ENRICHMENT New App Note! Agilent AssayMAP Sample Prep Platform Enables Reproducible Automated Phosphopeptide Enrichment. Advertisement Welcome to RAD Source Since 1997 Rad Source Technologies has been the expert in providing renewable, non-isotope, ionizing radiation replacements for self-shielded gamma irradiators. Currently, there are over 300 renowned hospital, university, and pharmaceutical research institutions using Rad Source X-ray technology. To find out more about our equipment, select your application and you will find equipment specifications, literature references, white papers, training videos, discussion forums, as well as other helpful info. Advertisement Fully automate your genomics workflow The Fragment Analyzer INFINITY is the only parallel capillary electrophoresis instrument capable of complete integration into your robotic automation system. Fully compatible with all the high quality kits developed for the Fragment Analyzer, the Fragment Analyzer INFINITY can run over 2400 samples a day without human intervention. Team Genetically Maps Lethal Strains of E. coli Genetic Engineering & Biotechnology News    Share    Scientists at the University of Maryland School of Medicine say they have for the first time determined the genetic makeup of various strains of E. coli, which every year kill hundreds of thousands of people around the world. Their paper, which appears in a recent issue of Nature Microbiology, analyzed the DNA of enteropathogenic Escherichia coli, which are the bacterial strains that cause diarrhea. More Advertisement Important factors to Consider for Thermal Shift Assays Download the Overcoming Technical Challenges in Cell-Based High Throughput Screens Whitepaper Scientists Team Up to Fight Zika Lab Manager    Share    Over the past seven months, two collaborating teams of scientists at Washington University School of Medicine — both focused on emerging infectious diseases — have redirected their efforts to concentrate on Zika virus. An outbreak of the mosquito-borne virus in the Americas has been linked to a startling surge of babies born with abnormally small heads and underdeveloped brains, a condition known as microcephaly, prompting new research aimed at answering critical questions about the virus. More Advertisement Become a Lab Superhero! The Mantis will revolutionize your workflow for applications including NGS sample prep, qPCR, assay development, and cellular assays. Automation made simple. Advertisement Cloud, Consulting, and Custom Services, All In One. Scigilian is a software company specializing in offering solutions to the problems encountered in pharmaceutical research, biotechnology, and contract research. Trusted, from large pharma to small CRO. Nature's Mirror: The Code for Chirality Science Daily    Share    New research, published in Nature Chemistry, explains how biological molecules can change the shape of minerals by controlling how they link together. Investigating why crystals of achiral minerals obtain a chiral shape — that is, how they take on a left- or right-handed nature — the research team showed how metal surfaces could be re-shaped by chiral molecules. More Antibiotic's Killer Strategy Revealed Phys.org    Share    Using a special profiling technique, scientists at Princeton have determined the mechanism of action of a potent antibiotic, known as tropodithietic acid (TDA), leading them to uncover its hidden ability as a potential anticancer agent. TDA is produced by marine bacteria belonging to the roseobacter family, which exist in a unique symbiosis with microscopic algae. The algae provide food for the bacteria, and the bacteria provide protection from the many pathogens of the open ocean. More Advertisement Nuclear Forensics: Scientific Analysis Supporting Law Enforcement and Nuclear Security Investigations Analytical Chemistry    Share    Nuclear forensic science, or "nuclear forensic," aims to answer questions about nuclear material found outside of regulatory control. In this feature, we provide a general overview of nuclear forensics, selecting examples of key "nuclear forensic signatures" which have allowed investigators to determine the identity of unknown nuclear material in real investigations. More Research Teams Use DNA to Make 3-D Nanoparticle Structures With High Precision Chemical & Engineering News    Share    DNA strands anchored to the surface of nanoparticles allow researchers to assemble the particles into three-dimensional crystalline lattices. Such control allows researchers to make new materials with desirable properties. In two recent studies, independent teams adapted this approach to gain even more control over assembly. More Advertisement KMC Systems Engineering & Manufacturing KMC Systems provides contract engineering and manufacturing services to leading and emerging OEMs. As a trusted outsourcing partner for 35 years, KMC Systems develops, designs and manufactures cutting-edge, full-system instrumentation for the medical and life science markets. Visit us online and download our brochure to learn more about KMC Systems. Advertisement The Concept Is Simple We work with scientists to design and develop new, innovative tools for biological, chemical, and materials research, both in basic studies and pharmaceutical and industrial applications. We know research, we know assay development, and we know tools development. Learn More Advertisement Sample Screening from your Compound The comPOUND system comprises a high-density sample storage unit and an additional suite of specialized delivery and processing modules to enable easy integration into any compound management or screening system. Slowing Aging The Scientist    Share    The accumulation of senescent cells in the body is associated with the development of a range of age-linked diseases, including arthritis, heart failure, and Alzheimer’s. Now, a mouse study from the Mayo Clinic in Rochester, Minnesota, suggests that purging these cells from the body might stave off the negative effects of aging. More Uncovering the Secrets of Elastin's Flexibility Bioscience Technology    Share    Elastin is a crucial building block in our bodies. Its flexibility allows skin to stretch and twist, blood vessels to expand and relax with every heartbeat, and lungs to swell and contract with each breath. But exactly how this protein-based tissue assembles itself to achieve this flexibility remained an unsolved question — until now. More Advertisement Sr. Scientist II, Cell Based Discovery The Coca-Cola Company US – GA – Atlanta Senior Product Manager Cell Culture/Biobanking Storage Products Thermo Fisher Scientific US – MA –Tewksbury Laboratory Automation Engineer/Associate Scientist or Sr. Engineer/Scientist, Process Development Genentech US – CA – South San Francisco Search Jobs at SLAS Career Connections   SLAS Point-to-Point Colby Horton, Vice President of Publishing, 469.420.2601 Download media kit Dennis Hall, Executive Editor, 469.420.2656    Contribute news This edition of SLAS Point-to-Point was sent to ##Email##. To unsubscribe from receiving SLAS Point-to-Point, click here. To unsubscribe from all SLAS e-mail communications, please click here. Did someone forward this edition to you? Subscribe here — it's free! SLAS Terms of Use Policy Recent issues Feb. 3, 2016 Jan. 27, 2016 Jan. 20, 2016 Jan. 13, 2016 7701 Las Colinas Ridge, Ste. 800, Irving, TX 75063