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Text version   RSS   Subscribe   Unsubscribe   Archive   Media Kit February 10, 2016

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Select SLAS2016 Presentations Now Available On Demand
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Seven podium presentations were recorded at SLAS2016 and are now available on-demand by full conference registrants (until March 31, 2016) and dues-paying SLAS members.

HT-MALDI-MS as a Complete Label-Free Drug Discovery Platform: From Target Characterization through High-Throughput Screening to Hit Follow Up (Scott Busby, Novartis Institutes for Biomedical Research, USA)

Development of a Platform to Enable Fully Automated Cross-Titration Experiments (Jason Cassaday, Merck, USA)

Identifying Druggable Cells: Automated Methods for High-Content Single-Cell Screening (Tiffany Chen, Cytobank, Inc. and Stanford University, USA)

High-Throughput Screening of Metagenomic DNA Libraries (Louis Cohen, Icahn School of Medicine at Mount Sinai, USA)

Genome Engineering with Zinc Finger Nucleases (Ed Rebar, Sangamo BioSciences, USA)

Droplet Microfluidics: Amphiphilic Nanoparticles as Droplet Stabilizers for High-Fidelity and Ultrahigh-Throughput Droplet Assays (Sindy Tang, Stanford University, USA)

Drug-Target Residence Time: Target Engagement, Target Vulnerability and Predictions of in Vivo Drug Activity (Peter Tonge, Stony Brook University, USA)
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SLAS Sets New Attendance Record at SLAS2016
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SLAS welcomed a record-setting 6,293 participants from 34 countries to SLAS2016, the Society's Fifth Annual International Conference and Exhibition, which convened Jan. 23-27 in San Diego, CA.

"As a Society, we're exceptionally pleased with the turnout, high quality of programming and tremendous professional networking that took place at SLAS2016," says SLAS President Richard Eglen. "That we established a new benchmark for participation is secondary to the highly positive feedback we have received from attendees, exhibitors and presenters as to how much they enjoyed the experience and the value they derived from attending. It's obvious that SLAS is filling an important niche for life sciences professionals and students."

Mark your calendar now for SLAS2017, Feb. 4-8, Washington, DC.
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Free at JBS Online: Characterization of Differentiated SH-SY5Y as Neuronal Screening Model Reveals Increased Oxidative Vulnerability
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A team from the Luxembourg Centre for Systems Biomedicine says, "the immortalized and proliferative cell line SH-SY5Y is one of the most commonly used cell lines in neuroscience and neuroblastoma research. However, undifferentiated SH-SY5Y cells share few properties with mature neurons. In this study, we present an optimized neuronal differentiation protocol for SH-SY5Y that requires only two work steps and six days. After differentiation, the cells present increased levels of ATP and plasma membrane activity but reduced expression of energetic stress response genes." More


From the SLAS President: SLAS Never Ceases to Amaze Me
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"As I write this, my head is still spinning from an invigorating and exciting SLAS2016 in San Diego," says SLAS President Richard Eglen in his first column in the SLAS Electronic Laboratory Neighborhood e-zine.

"The energy and enthusiasm were palpable everywhere I looked; morning, noon and night. It was so impressive and gratifying to see nearly 6,300 life sciences professionals from 34 countries engaged in the science, the educational program and, as importantly, with each other. SLAS never ceases to amaze me with its openness and friendly sense of collegiality, and our diversity within such a uniquely focused scope truly is one of our greatest strengths as an organization."
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Vote by Feb. 19 for Your Favorite Finalist in the JALA & JBS Art of Science Contest
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Ten finalists have been selected, and now it's up to the SLAS community to decide which one will receive the grand prize of a $500 Amazon gift card for the most mesmerizing scientific image.

Vote for your favorite finalist by 5:00 p.m. U.S. Eastern time on Feb. 19, 2016. SLAS members and nonmembers are welcome to vote. There are entries from Australia, China, Italy, New Zealand, Switzerland, United Kingdom and United States.
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JALA Special Issue Call for Papers: Micro and Nanotechnologies for Quantitative Biology and Medicine
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A quantitative approach to biology and medicine is essential for understanding how biological systems respond to dynamically changing environments and for developing new therapeutic strategies to combat disease. Recent advancements in micro and nanotechnologies have revolutionized biomedical research in engineering controlled interfaces to biological systems. These quantitative enabling technologies hold great potential to accelerate early diagnosis and treatment of disease.

JALA Guest Editor Somin Eunice Lee of the University of Michigan invites abstract submissions for the special issue by April 1, 2016 that highlight and explore diverse quantitative approaches and their applications.
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Team Genetically Maps Lethal Strains of E. coli
Genetic Engineering & Biotechnology News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Scientists at the University of Maryland School of Medicine say they have for the first time determined the genetic makeup of various strains of E. coli, which every year kill hundreds of thousands of people around the world. Their paper, which appears in a recent issue of Nature Microbiology, analyzed the DNA of enteropathogenic Escherichia coli, which are the bacterial strains that cause diarrhea. More


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Scientists Team Up to Fight Zika
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Over the past seven months, two collaborating teams of scientists at Washington University School of Medicine — both focused on emerging infectious diseases — have redirected their efforts to concentrate on Zika virus. An outbreak of the mosquito-borne virus in the Americas has been linked to a startling surge of babies born with abnormally small heads and underdeveloped brains, a condition known as microcephaly, prompting new research aimed at answering critical questions about the virus. More


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Nature's Mirror: The Code for Chirality
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New research, published in Nature Chemistry, explains how biological molecules can change the shape of minerals by controlling how they link together. Investigating why crystals of achiral minerals obtain a chiral shape — that is, how they take on a left- or right-handed nature — the research team showed how metal surfaces could be re-shaped by chiral molecules. More


Antibiotic's Killer Strategy Revealed
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Using a special profiling technique, scientists at Princeton have determined the mechanism of action of a potent antibiotic, known as tropodithietic acid (TDA), leading them to uncover its hidden ability as a potential anticancer agent. TDA is produced by marine bacteria belonging to the roseobacter family, which exist in a unique symbiosis with microscopic algae. The algae provide food for the bacteria, and the bacteria provide protection from the many pathogens of the open ocean. More


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Nuclear Forensics: Scientific Analysis Supporting Law Enforcement and Nuclear Security Investigations
Analytical Chemistry    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Nuclear forensic science, or "nuclear forensic," aims to answer questions about nuclear material found outside of regulatory control. In this feature, we provide a general overview of nuclear forensics, selecting examples of key "nuclear forensic signatures" which have allowed investigators to determine the identity of unknown nuclear material in real investigations. More


Research Teams Use DNA to Make 3-D Nanoparticle Structures With High Precision
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DNA strands anchored to the surface of nanoparticles allow researchers to assemble the particles into three-dimensional crystalline lattices. Such control allows researchers to make new materials with desirable properties. In two recent studies, independent teams adapted this approach to gain even more control over assembly. More


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Slowing Aging
The Scientist    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The accumulation of senescent cells in the body is associated with the development of a range of age-linked diseases, including arthritis, heart failure, and Alzheimer’s. Now, a mouse study from the Mayo Clinic in Rochester, Minnesota, suggests that purging these cells from the body might stave off the negative effects of aging. More


Uncovering the Secrets of Elastin's Flexibility
Bioscience Technology    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Elastin is a crucial building block in our bodies. Its flexibility allows skin to stretch and twist, blood vessels to expand and relax with every heartbeat, and lungs to swell and contract with each breath. But exactly how this protein-based tissue assembles itself to achieve this flexibility remained an unsolved question — until now. More


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Career


Sr. Scientist II, Cell Based Discovery
The Coca-Cola Company
US – GA – Atlanta

Senior Product Manager Cell Culture/Biobanking Storage Products
Thermo Fisher Scientific
US – MA –Tewksbury

Laboratory Automation Engineer/Associate Scientist or Sr. Engineer/Scientist, Process Development
Genentech
US – CA – South San Francisco

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