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Text version   RSS   Subscribe   Unsubscribe   Archive   Media Kit February 14, 2018    SLAS2018    Moving? New job? Let SLAS know.      







Paul Ju Sung Hung Earns 2018 SLAS Innovation Award
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Paul Ju Sung Hung, Ph.D., chief executive officer of COMBiNATi, Palo Alto, CA, took home top honors and $10,000 for his SLAS2018 presentation "Microfluidic Siphoning Array (MSA) — A Novel Scalable Digital PCR Integrated Platform." In his presentation, Hung described the advantages enabled by this platform, which include lowering both the workflow and cost barriers of digital PCR without compromising the performance in precision and sensitivity. In addition to the cash award, Hung receives an SLAS Premier membership, is invited to have his work featured in either SLAS Discovery or SLAS Technology and joins the judging panel for the 2019 SLAS Innovation Award. More


Hickey, Wang and Mullapudi Win SLAS2018 Student Poster Competition
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Three winners of the SLAS2018 Student Poster Competition received $500 cash prizes for outstanding innovative research conducted by students, graduate students, post-doctoral associates and junior faculty (less than four years in first academic appointment).

Congratulations go to:

John Hickey of Johns Hopkins University for "High-Throughput Enrichment and Identification of Rare Antigen-specific CD8+ T Cells"

Xiao Wang of the BioMEMS Resource Center, Massachusetts General Hospital, Harvard Medical School, for "Squeeze & Chemotax: A High-Throughput Microfluidic Assay for Probing the Effect of Deformation on Leukocyte Chemotaxis"

Sri Teja Mullapudi of Max Planck Institute for Heart and Lung Research for "In Vivo Screening to Identify Insulin-Independent Modulators of Metabolism Identifies Novel Candidates"

SLAS Journal Editors-in-Chief Reveal Secrets for Successful Scientific Paper Publication
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SLAS Discovery Editor-in-Chief Robert M. Campbell (Eli Lilly & Company) and SLAS Technology Editor-in-Chief Edward Kai-Hua Chow (National University of Singapore) were busy at SLAS2018. They greeted prospective authors in the SLAS Journals Information Station and shared a step-by-step overview of how to design and write scientific research papers more clearly and effectively to improve their chances for publication. More

Sponsored Content

Congratulations SLAS2018 New Product Award Winners
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Three SLAS2018 exhibiting companies shared best-of-show honors for their innovative and exciting new products. Judged for their products’ market opportunity, impact, originality and proof of concept, the winning entries include:

FORMULATRIX for its CONSTELLATION Digital PCR System, a novel microfluidic platform that provides high-throughput absolute quantification of up to five target DNA or RNA molecules for EvaGreen or probe-based digital PCR applications.

Labcyte for the Echo 655T Acoustic Liquid Handler that offers all the benefits associated with non-contact liquid transfer with the new ability to transfer directly from Echo Qualified sample tubes, enabling an all acoustic workflow from sample store to screening assay.

iotaSciences for the isoCell that advances, automates and accelerates single-cell work using fluidic walls.

NEW! Keynote Speakers Announced for 2018 SLAS Europe Conference and Exhibition
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A futurist, a thought leader in life sciences collaboration and a policy maker from the European Commission headline the speakers to appear at the inaugural 2018 SLAS Europe Conference and Exhibition to be held June 27-29 in Brussels. Register now to see futurist Peter Hinssen, Mathias Uhlén of the Karolinska Institute, Stockholm, Sweden; and Max Lemke, head of unit, Components and Systems of the European Commission, Brussels, Belgium.

ATTENTION life sciences discovery and technology startups! Apply today for an opportunity to appear on SLAS Innovation AveNEW at the new SLAS Europe Conference and Exhibition! Grow and scale your product and/or service concept by directly connecting with decision-makers from across Europe. The deadline is March 15.

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Keynote Speakers Announced for SLAS2019
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SLAS2019 keynote speakers address weighty issues at the SLAS International Conference and Exhibition to be held Feb 2-6, 2019, in Washington, D.C. Opening keynote speaker Teresa K. Woodruff, Ph.D., dean and associate provost for graduate education in The Graduate School at Northwestern University, addresses genetic medicine. Closing keynote speaker Eran Segal, Ph.D., Weizmann Institute of Science, Israel, discusses "The Algorithm Diet," which is based on his research into an algorithm that accurately predicts post-meal blood sugar levels based on a person's individual biological makeup and lifestyle. More

Real Stories about Real People
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See what's new and who's who in the SLAS Electronic Laboratory Neighborhood e-zine! Plus, a new video on the SLAS YouTube channel promotes the latest news, research highlights and profiles of life science professionals. More

AMRI’s integrated drug discovery centers of excellence combine scientific expertise and leading-edge technology to accelerate innovation. Our complete suite of solutions includes comprehensive discovery biology, synthetic and medicinal chemistry, DMPK and bioanalytical services for successful hit-to-lead-to-candidate selection.

Contact us to put our Discovery expertise to work for you, contact:

Success Stories from SLAS2018
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Immerse yourself in highlights of SLAS2018! Participants and exhibitors share stories from the 2018 SLAS International Conference and Exhibition held Feb 3-7 in San Diego. More


Drug Development Success Rates Are Higher Than Previously Reported
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The largest study yet assessing the success rates of clinical trials for drugs has yielded more optimistic data than previous studies. Andrew W. Lo and colleagues at the MIT Laboratory for Financial Engineering used an automated algorithm to draw data from nearly 186,000 unique trials of over 21,000 compounds, from January 2000 through October 2015. The team found that 13.8% of drug programs make it from Phase I to approval, a higher figure than the often-touted estimates of 5% or 10%. More

Explore the Latest Festo Innovations

Join Festo as we kick off the new year at SLAS in San Diego, CA. Discover our latest products and innovative technologies for laboratory automation at booth 637. Stop by and speak with our experts to help find a solution for your laboratory challenges.

Chemists Develop Motion Capture-Like Technology for Tracking Protein Shape    Share    Share on FacebookTwitterShare on LinkedinE-mail article
In many modern animated movies, the trick to achieving realistic movements for individual characters and objects lies in motion-capture technology. This process often involves someone wearing a tracking suit covered in small, colored balls while a camera captures the position of those colored balls, which is then used to represent how the person is moving. Researchers at the University of Pennsylvania are developing a similar technology to obtain atomic-resolution "movies" that track how proteins fold and change shape. More

Mesoscale Graphene-like Honeycomb Mono- and Multilayers Constructed via Self-Assembly of Coclusters
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Honeycomb structure endows graphene with extraordinary properties. But could a honeycomb monolayer superlattice also be generated via self-assembly of colloids or nanoparticles? Here we report the construction of mono- and multilayer molecular films with honeycomb structure that can be regarded as self-assembled artificial graphene. We construct fan-shaped molecular building blocks by covalently connecting two kinds of clusters, one polyoxometalate and four polyhedral oligomeric silsesquioxanes. More

New Method Overcomes Cancer Cells' Multidrug Resistance
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Scientists have developed a novel technique that uses specially designed nanoparticles and near-infrared laser treatment to cause cancer cells to lose their multidrug resistance capabilities for days at a time. This creates a therapeutic window for chemotherapy to combat even the most drug-resistant cells left behind after surgery or earlier treatment, according to the researchers. The group's findings ("Targeted Production of Reactive Oxygen Species in Mitochondria to Overcome Cancer Drug Resistance") were published in Nature Communications. More

A Super Resolution View of Chemical Reactions
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Researchers from the Institute of Physical Chemistry of the Polish Academy of Sciences have demonstrated, using a super resolution microscopic technique, how to follow chemical reactions taking place in very small volumes. The method of analysis developed by the Warsaw physicists in collaboration with PicoQuant GmbH is the first to make it potentially possible to observe reactions not only inside living cells, but even within individual organelles, such as cell nuclei. More

A New Role for the 'Pigments of Life'
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In nature, porphyrins are responsible for the green color of leaves and the red color of blood. All their functionality is based along the same core chemical structure: four smaller rings connected to one larger ring, with a little cavity in the center. Most of their functions in nature (photosynthesis, oxygen transport) arise when they host different guest metals (magnesium, iron, cobalt, nickel) in the centre of the molecule. Different metals spark different functions in these "metalloporphyrins." More

DNA Robots Target Cancer
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DNA nanorobots that travel the bloodstream, find tumors, and dispense a protein that causes blood clotting trigger the death of cancer cells in mice, according to a study published in Nature Biotechnology. The authors have "demonstrated that it’s indeed possible to do site-specific drug delivery using biocompatible, biodegradable, DNA-based bionanorobots for cancer therapeutics," says Suresh Neethirajan, a bioengineer at the University of Guelph in Ontario, Canada, who did not participate in the study. More

Peptide Could Help with Diabetes, Weight Loss
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Treating obese mice with catestatin, a peptide naturally occurring in the body, showed significant improvement in glucose and insulin tolerance and reduced body weight, report University of California San Diego School of Medicine researchers. In a study published in Diabetes, researchers identified CST's role in the recruitment and function of macrophages in the liver as well as regulation of obesity-induced liver inflammation and insulin resistance. More


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