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Text version   RSS   Subscribe   Unsubscribe   Archive   Media Kit February 17, 2016    SLAS2016    SLAS2017    Moving? New job? Let SLAS know.      










Now Online: SLAS2016 Keynote Presentation 'Analyzing the Complexity of Drug Resistance in Cancer'
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The SLAS2016 opening keynote presentation by NIH Deputy Director for Intermural Research Michael M. Gottesman, M.D., is available on demand free-of-charge to the general public.

In addition, seven podium presentations from SLAS2016 are now available as on demand webinars for dues-paying SLAS members. Join or renew your membership to access immediately.


Deadline Friday, Feb. 19: JALA & JBS Art of Science Contest
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Ten finalists have been selected, and now it's up to the SLAS community to decide which one will receive the grand prize of a $500 Amazon gift card for the most mesmerizing scientific image.

Vote for your favorite finalist by 5:00 p.m. U.S. Eastern time on Feb. 19, 2016. Competing for the prize are scientists from Switzerland, Australia, Italy, China, New Zealand, the U.S. and the U.K.

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SLAS ELN Reports: The Lab Man — Straight Talk with SLAS2016 Innovators
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SLAS2016 was a vast playground for the nearly 6,300 participants immersed in education, exploration and connection for five days in January.

The Lab Man talks with SLAS Student Poster Competition (Joohun Kang, Carrie Lovitt and Masturah Bte Mohd Abdul Rashid) and SLAS New Product Award (Luc Talini of ALVEOLE, Catherine Parrish of Axion BioSystems and Jochen Klingelhoefer of LabMinds) winners, allowing listeners a window into the minds of these creative SLAS innovators.


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JALA and JBS Calls for Papers
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JALA and JBS are accepting proposals (abstracts) for original, high-quality, research and review papers in five categories:

Cancer Metabolism
JBS manuscript proposals due April 1, 2016
Guest Editors: Raymond Gilmour, Ph.D., of Eli Lilly and Company (USA); and Susana Velasco-Miguel, Ph.D., of CNIO (Spain)

Micro- and Nanotechnologies for Quantitative Biology and Medicine
JALA manuscript proposals due April 1, 2016
Guest Editor: Somin Eunice Lee, Ph.D., of University of Michigan

3D Cell Culture, Drug Screening and Optimization
JBS manuscript proposals due June 1, 2016
Guest Editors: Richard Eglen, Ph.D. of Corning Life Sciences and Jean-Louis Klein, Ph.D. of GlaxoSmithKline

Personalized and Precision Medicine
JALA manuscript proposals due June 1, 2016
Guest Editors: Dean Ho, Ph.D., and Ali Zarrinpar, M.D., Ph.D., of University of California, Los Angeles

Quantitative Imaging in Life Sciences and Biomedical Research
JALA manuscript proposals due April 1, 2017
Guest Editors: Anand D. Jeyasekharan, MRCP (UK), Ph.D., of National University of Singapore; and Jonathan E. Cechetto, Ph.D., of PerkinElmer

Submit your work to these internationally recognized, MEDLINE-indexed journals, now in their 21st year of publication. JALA and JBS address the full spectrum of issues that enable scientific research teams to gain insights, increase productivity, elevate data quality, reduce lab process cycle times and enable experimentation that otherwise would be impossible. JALA and JBS special issues are widely read and highly cited.


SLAS Europe: Conference on Compound Management
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The SLAS Compound Management in Industry and Academia Conference, April 12-13 in Berlin, Germany, offers guidance in how to choose the right compounds at the right times and in the best possible quality to maximize the generation of meaningful screening, pharmacological, toxicological or ADME profiling data.

The conference includes scientific sessions, case studies, networking, exhibits and poster presentations. It is appropriate for all compound management and lead discovery professionals from bench scientists to senior leaders in the pharmaceutical, biotechnology and agri-science industries as well as from academic drug discovery.


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Scientists Gain Insights Into 'Forbidden' Chemistry
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Gabriele Saleh, a research fellow at MIPT, and Prof. Artem Oganov, a laboratory supervisor at MIPT and professor at the Skolkovo Institute of Science and Technology, have discovered what causes the stability of various compounds that are not commonly found in "textbook" chemistry. The reorganization of the chemical interactions results in the stability of the "new" structure of the compounds. The results of the study have been published in the journal Physical Chemistry & Chemical Physics. More

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Scientists Scramble to Develop Tools, Treatments for Zika Virus
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When the Pan American Health Organization put out an alert last May about the first confirmed cases of Zika virus infection in Brazil, the news barely registered. After all, compared with other mosquito-borne viruses, such as potentially life-threatening dengue and yellow fever, Zika seemed pretty harmless. Only 20% of people infected with Zika even become ill, and their symptoms tend to be mild — fever, rash, joint pain, and conjunctivitis. More

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Hydrogels Can Put Stem Cells to Sleep    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Unlike normal cells, stem cells are pluripotent — they can become any cell type, which makes them powerful potential treatments for diseases such as diabetes, leukemia and age-related blindness. However, maintaining this versatility until the time is right is a major challenge. In ACS Central Science, researchers reveal that mimicking a natural process called diapause can halt stem cells, effectively putting them to sleep for up to two weeks. More

Antibody Alternatives
The Scientist    Share    Share on FacebookTwitterShare on LinkedinE-mail article
There is a growing reproducibility problem across the life sciences. The retraction rate of published papers has increased tenfold over the past decade, and researchers have reported only being able to replicate published results in 11 percent or 25 percent of attempts. It's become known as the "reproducibility crisis," and science is in a race to fix it. One major factor contributing to this problem is the use of poorly validated research antibodies. More


Shock Wave Mediated Plume Chemistry for Molecular Formation in Laser Ablation Plasmas
Analytical Chemistry    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Although it is relatively straightforward to measure the ionic, atomic, molecular, and particle emission features from laser ablation plumes, the associated kinetic and thermodynamic development leading to molecular and nanocluster formation remain one of the most important topics of analytical chemistry and material science. Very little is known, for instance, about the evolutionary paths of molecular and nanocluster formation and its relation to laser plume hydrodynamics. More

Chemical Cages: New Technique Advances Synthetic Biology
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Living systems rely on a dizzying variety of chemical reactions essential to development and survival. Most of these involve a specialized class of protein molecules — the enzymes. In a new study, Hao Yan, director of the Center for Molecular Design and Biomimetics at Arizona State University's Biodesign Institute presents a clever means of localizing and confining enzymes and the substrate molecules they bind with, speeding up reactions essential for life processes. More

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Gene Linked to Patients' Response to Infectious Diseases
Genetic Engineering & Biotechnology News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Scientists led by a group in the Center for Vascular Biology Research at Beth Israel Deaconess Medical Center have shown that variations in the Tie2 gene, which is expressed on the inner surface of blood vessels, play an important role in patient responses to infectious diseases. The new study, which appears online in PNAS, demonstrates that diminished Tie2 levels are associated with potentially devastating responses to infections, while higher Tie2 levels provide protection. More

Engineering Material Magic
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University of Utah engineers have discovered a new kind of 2-D semiconducting material for electronics that opens the door for much speedier computers and smartphones that also consume a lot less power. The semiconductor, made of the elements tin and oxygen, or tin monoxide, is a layer of 2-D material only one atom thick, allowing electrical charges to move through it much faster than conventional 3-D materials such as silicon. More



Principal Scientist, Cell Biology & Imaging
BioTek Instruments, Inc.
US – VT – Burlington

Post-Doc Fellow – Molecular Imaging
National Institutes of Health
US – MD – Bethesda

Research Scientist II – Pharmacology
Geisinger Health System
US – PA – Danville

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