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Text version   RSS   Subscribe   Unsubscribe   Archive   Media Kit February 18, 2015    SLAS2015    Moving? New job? Let SLAS know.    









Jonathan Wingfield Wins 2015 SLAS Innovation Award
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Wingfield of AstraZeneca in Cambridge, UK, took home the $10,000 prize for his scientific presentation, Novel Acoustic Loading of a Mass Spectrometer — Towards Next Generation High Throughput MS Screening. He described the unique, innovative solution his team explored to the problem of throughput by using acoustic droplet ejection (ADE) to transfer femtoliter samples from microliter assays rapidly, precisely and accurately directly into a mass spectrometer.

Wingfield's talk is one of 10 recorded at SLAS2015 for on-demand access beginning later this month for SLAS dues-paid members and SLAS2015 full conference attendees. Wingfield also is a guest editor for the JBS Special Issue on Advances in Mass Spectrometry within Drug Discovery; manuscript proposals for the special issue are due April 10.


Hurry! Vote before Feb. 20 for Your Favorite Finalist in the Art of Science Contest
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There's still time to visit to vote for your favorite finalist in the 2015 JALA & JBS Art of Science Contest. The top vote-getter will win a $500 Amazon gift card and a full registration to SLAS2016. Voting ends at 5 p.m. U.S. Eastern time on Feb. 20. More

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Four Companies Selected for SLAS2015 New Product Award
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296 companies participated in the SLAS2015 Exhibition, 61 of which launched new products to be considered for the SLAS2015 New Product Award. The winners were:

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  • Champ, Grist and Wijaya Win SLAS2015 Student Poster Awards
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    Recognizing innovative research by students, graduate students, post-doctoral associates and junior faculty, the SLAS2015 Student Poster Competition carries cash awards of $500 each to the top three poster authors. The winners and their posters are:

    Kathryn Champ, Johns Hopkins University
    Screening for Synergy of Resveratrol and Repurposed Drugs Towards Retinoblastoma

    Samantha Grist, University of British Columbia, Vancouver
    A Microfluidic Device with Integrated Oxygen Sensors for the Cell-Based Screening of Cancer Treatments under Transient Hypoxia

    Juwina Wijaya, University of California Los Angeles
    Utilizing Small Molecules to Study Mitochondria Presequence-degrading Protease

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    SLAS Scientific Journals Honor Achievement by Authors and Reviewers
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    During a special SLAS2015 reception, JBS Editor-in-Chief Robert M. Campbell, Ph.D., of Eli Lilly and Company, and JALA Editor-in-Chief Edward Kai-Hua Chow, Ph.D., of the National University of Singapore, announced honorees in three categories.

    2015 Readers Choice Awards: 2015 Authors Choice Awards: 2015 JBS Reviewer Excellence Awards:
    • Juan Manuel Dominguez, PharmaMar, Madrid (Spain)
    • Fernando Peláez, Spanish National Cancer Research Center, Madrid (Spain)
    • Steven Haney, Eli Lilly and Company, Indianapolis, IN (USA)
    Readers Choice and Authors Choice articles are freely available at JBS Online or JALA Online.


    Mark Your Calendar for SLAS2016
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    As announced during the close of SLAS2015, SLAS2016 will take place Jan. 23-27, 2016, in San Diego, California. Keynote speakers for the event include Michael Gottesman, chief of the Laboratory of Cell Biology at the U.S. National Cancer Institute, and Adam Diedrich Steltzner, engineer at NASA's Jet Propulsion Laboratory. SLAS will begin accepting presentation abstracts in March. Watch for the latest event information. More

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    Miss an Issue of the SLAS2015 Daily News?
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    This news brief was issued four days to help conference and exhibition participants navigate SLAS2015. You still can reference the news, notes, photos and videos at:

    Sunday, Feb. 8
    Monday, Feb. 9
    Tuesday, Feb. 10
    Wednesday, Feb. 11

    Additional SLAS2015 photos can be viewed on the SLAS Facebook page and SLAS2015 videos on the SLAS channel on YouTube.


    NIH Director: Opportunities From Technology in Medical Science
    By Jessica Taylor    Share    Share on FacebookTwitterShare on LinkedinE-mail article
    Francis Collins, M.D., Ph.D., National Institutes of Health director, spoke at SLAS2015 about the exceptional opportunities currently facing the medical science community. Collins began discussing with the group the mission of NIH — to seek fundamental knowledge about the nature and behavior of living systems and the application of that knowledge to enhance health, lengthen life and reduce illness and disability — and how each and every person at the conference affected it in some way or another. More


    Human 'Organs-on-Chips' as Replacements for Animal Testing
    By Jessica Taylor    Share    Share on FacebookTwitterShare on LinkedinE-mail article
    Wyss Institute Founding Director Donald E. Ingber, M.D., Ph.D., kicked off SLAS2015 by focusing on the engineering of human "Organs-on-Chips" to a filled room of SLAS attendees Feb. 9. Researchers, along with Ingber, have created this innovative technology. Organs-on-a-Chip is a cell culture device — crystal clear with flexible polymers and the size of a computer memory stick — that contains hollow channels lined by living cells, and tissues that imitate human cellular response far more effectively and realistically than Petri dish cultures. More

    Scientists Shed Light on Controversial Theory of Protein Structure    Share    Share on FacebookTwitterShare on LinkedinE-mail article
    A team of chemists, biochemists and mathematicians at the University of Bristol have published a paper in the journal Nature Chemical Biology, which explores how protein structures are stabilized. There are many forces that hold together the three-dimensional, functional structures of proteins. Despite considerable effort, understanding of these forces is still quite rudimentary. More

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    Adatoms Underneath Single Porphyrin Molecules on Au(111)
    Journal of the American Chemical Society    Share    Share on FacebookTwitterShare on LinkedinE-mail article
    The adsorption of porphyrin derivatives on a Au(111) surface was studied by scanning tunneling microscopy and spectroscopy at low temperatures in combination with density functional theory calculations. Different molecular appearances were found and could be assigned to the presence of single gold adatoms bonded by a coordination bond underneath the molecular monolayer, causing a characteristic change of the electronic structure of the molecules. More

    First Glimpse of a Chemical Bond Being Born
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    Scientists have gotten the first glimpse of the transition state where two atoms begin to form a weak bond on the way to becoming a molecule. This fundamental advance, long thought impossible, will have a profound impact on the understanding of how chemical reactions take place and on efforts to design reactions that generate energy, create new products and fertilize crops more efficiently. More

    Search Engine Helps Predict Gene Function
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    Now, School of Medicine researchers have developed a comparative search engine that uses evolutionary correlations between humans and other species" genes to help identify human gene function. "After the human genome was sequenced, scientists thought it would be a very short time before we knew what all the genes are doing," said Tobias Meyer, PhD, professor and chair of chemical and systems biology. More

    Biochemist Sheds Light on Structure of Key Cellular 'Gatekeeper'
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    Facing a challenge akin to solving a 1,000-piece jigsaw puzzle while blindfolded — and without touching the pieces — many structural biochemists thought it would be impossible to determine the atomic structure of a massive cellular machine called the nuclear pore complex, which is vital for cell survival. But after 10 years of attacking the problem, a team led by André Hoelz, assistant professor of chemistry, recently solved almost a third of the puzzle. More

    Native Stem Cells, Transplants Form Blood Differently
    Genetic Engineering & Biotechnology News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
    Blood cell formation, the process by which stem cells perpetuate streams of differentiated cells, is characterized by very different flows, depending on whether the ultimate font consists of transplanted stem cells or normal, unperturbed stem cells. Transplanted stem cells, it is well known, may give rise to all the cell types of the blood, even though very few of the transplanted stem cells — a tiny pool of long-term hematopoietic stem cells — sustain the upwelling. More

    Crystalline Sponges Catching on With Chemists
    Chemical & Engineering News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
    The bottom of the liquid-filled vial held by Timothy R. Ramadhar shimmers brilliantly in the afternoon sun flooding through the window near his lab bench. It's a cold winter day in Boston, and Ramadhar, a postdoc in Jon Clardy's lab at Harvard Medical School, is showing off some sparkly crystalline sponges — the key element in what he and many others say could be a coup in chemical structure elucidation. More


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