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Text version   RSS   Subscribe   Unsubscribe   Archive   Media Kit February 22, 2017

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Ed Chow Talks About The 2017 SLAS Technology Ten
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From being able to move liquid with sound to dispense primary cells and DNA to microfluidic-based immunoassays, SLAS Technology Editor-in-Chief Edward Kai-Hua Chow (National University of Singapore) talks about the groundbreaking achievements reflected in The 2017 SLAS Technology Ten, published earlier this month.

This year’s highlights push the envelope of what is possible with automation, integrating new functions into high-throughput sample preparation and screening to further drive efficiencies in research.
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SLAS2017 Survey Still Sitting in Your Inbox?
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SLAS2017 participants: Please complete the SLAS2017 Conference Evaluation that was sent to you via e-mail originally on Feb. 8, with a reminder sent Feb. 15. Your feedback is very important to SLAS and is used to shape future SLAS conferences — including SLAS2018. Plus, everyone who completes the survey has a chance to win a $50 American Express gift certificate.

Please take five minutes and help SLAS help you! The deadline for survey responses is Friday, Feb. 24.


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Discovery. Technology. — Inseparable. In Sync. In Demand.
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The SLAS global community relies on the official journals of SLAS — SLAS Discovery (Advancing Life Sciences R&D) and SLAS Technology (Translating Life Sciences Innovation) — to gain scientific insights; increase productivity; elevate data quality; reduce process cycle times; and enable R&D that otherwise would be impossible.

The official journals of SLAS: Backed by the world-class education standards of SLAS; rigorously peer-reviewed; MEDLINE-indexed; no article processing charges; and open access publishing options.
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Coming Soon: 2017 SLAS Europe Compound Management Conference
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Breaking Down Walls — Uniting Sample Management Communities to Advance Scientific Innovation: Effective design and management of compound collections is crucial to the success of research efforts in the pharmaceutical, biotechnology and agri-science industries.

In addition, academic organizations are establishing comprehensive compound management infrastructures to help realize their target validation and drug discovery goals. Learn how to provide the right compound at the right time and in the best possible quality March 14-15 in Berlin.
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Call for Papers: Quantitative Imaging in Life Sciences and Biomedical Research
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SLAS Technology invites special issue manuscript proposals (abstracts) on topics related to the use of quantitative imaging methodologies in life sciences and biomedical research, including but not limited to novel technologies for quantitative and high-content imaging, high-throughput applications of advanced microscopy, advances in image analysis and processing of high-content data, novel biological and chemical reagents to facilitate quantitative imaging, and standardization and benchmarking in imaging. Proposal due date is April 1. More


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Job Seekers and Employers Connect via SLAS Career Connections
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Visit this targeted employment exchange regularly to keep up to date with opportunities. Job seekers can post resumes and browse job openings for free. Employers can find new talent by reviewing posted resumes for free and attract new talent by posting job openings for a fee. SLAS Corporate Members receive a 50% discount on job postings. More




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Women Recognized for Big Impact on Science, Research
By Suzanne Mason    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The theme of SLAS2017, the annual international conference and exhibition from the Society for Laboratory Automation and Screening, was "Research: The Possibilities." And that theme of looking forward to the future remained strong during the closing remarks of the conference. "Today, this is the end of talking about Marie Curie," said closing keynote speaker Rachel Swaby, author of the book, "Headstrong: 52 Women Who Changed Science — and the World." More


Researchers Are First to See DNA 'Blink'
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Many of the secrets of cancer and other diseases lie in the cell's nucleus. But getting way down to that level — to see and investigate the important genetic material housed there — requires creative thinking and extremely powerful imaging techniques. Vadim Backman and Hao Zhang, nanoscale imaging experts at Northwestern University, have developed a new imaging technology that is the first to see DNA "blink," or fluoresce. More


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Panel Foresees Changes at FDA, Action on Drug Prices and Obamacare
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Donald Trump's administration will redirect the FDA, tackle the price of prescription drugs, and repeal, if not immediately replace, the Affordable Care Act, a panel of biopharma leaders, advocates, and observers predicted. How dramatically the FDA changes direction under Trump will have consequences beyond the agency, affecting biopharma industry growth and investment in early-stage companies, one panelist warned. More


Mass Defect-Based N,N-Dimethyl Leucine Labels for Quantitative Proteomics and Amine Metabolomics of Pancreatic Cancer Cells
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Mass spectrometry-based stable isotope labeling has become a key technology for protein and small-molecule analyses. We developed a multiplexed quantification method for simultaneous proteomics and amine metabolomics analyses via nano reversed-phase liquid chromatography–tandem mass spectrometry (nanoRPLC–MS/MS), called mass defect-based N,N-dimethyl leucine (mdDiLeu) labeling. More




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Mechanistic Insights into Tunable Metal-Mediated Hydrolysis of Amyloid-β Peptides
Journal of the American Chemical Society    Share    Share on FacebookTwitterShare on LinkedinE-mail article
An amyloidogenic peptide, amyloid-β (Aβ), has been implicated as a contributor to the neurotoxicity of Alzheimer’s disease (AD) that continues to present a major socioeconomic burden for our society. Recently, the use of metal complexes capable of cleaving peptides has arisen as an efficient tactic for amyloid management; unfortunately, little has been reported to pursue this strategy. More


New Amination Chemistry Brought to Light
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Flashes of light help chemists at Princeton University and Bristol-Myers Squibb drive the hydroaminations of olefins to produce substituted amines. The light-powered reaction gives chemists another tool for installing amines in drugs and other biologically important molecules. The new hydroamination is noteworthy for its intermolecular reactivity, its use of unactivated olefin substrates, its toleration of several different functional groups, and its regioselectivity for anti-Markovnikov amine products — wherein the new C–N bond forms on the less substituted carbon of the olefin. More


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Researchers Develop Unique Model to Customize Common Industrial Process
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Lawrence Livermore National Laboratory (LLNL) researchers have published a precise computer model of a deposition process using electrically charged particles that will provide scientists and engineers with unprecedented insights into the method. The process of electrophoretic deposition (EPD) uses an electric field to drive colloidal particles suspended in a liquid from a solution onto a conductive substrate. More


Molecular Phenomenon Discovered by Advanced NMR Facility
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Cutting edge technology has shown a molecule self-assembling into different forms when passing between solution state to solid state, and back again — a curious phenomenon in science — says research by the University of Warwick. Professor Steven P. Brown from the Department of Physics, with colleagues in the Department of Chemistry, have identified that the supramolecular structure of a guanosine derivative can be different upon passing from the solid state into the solution state and vice versa. More


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Glowing Mice Suggest New Gene Therapy Technique
Bioscience Technology    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Timothy Blake, a postdoctoral fellow in the Waymouth lab, was hard at work on a fantastical interdisciplinary experiment. He and his fellow researchers were refining compounds that would carry instructions for assembling the protein that makes fireflies light up and deliver them into the cells of an anesthetized mouse. If their technique worked, the mouse would glow in the dark. More




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Associate Director for Clinical Chemistry
Geisinger Health System
US – PA – Danville

Field Applications Specialist
Hamilton Company
US – CA – San Diego

Product Manager
Artel
US – ME – Westbrook

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