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Certified UPS’s to protect your laboratory’s critical instrumentation and resolve current and potential power issues.
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Speed, sensitivity and precision in all detection modes. BMG LABTECH’s PHERAstar FS has no equal.
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Interactive e-zine sharing experiences and perspectives on science-related topics.
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Discussions and musings focused on the engaging field of laboratory science and technology.
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SLAS Spring Webinar Series: Effectively Managing Collaborative Science
SLAS Share
   
Collaborative science may involve working across groups or companies on the other side of town or across the ocean. Learn to formulate strategy, employ best practices and establish successful long-term collaborations from webinar leaders Ajay Gautam of AstraZeneca, Jonathan H. Connick of Merck and Liming Shi of Eli Lilly, who will present March 20, April 17 and May 15, respectively. Webinars are free to paid SLAS members, and registration is open.
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Three SLAS e-members awarded Breakthrough Prize in Life Sciences
SLAS Share
Lewis C. Cantley, Napoleone Ferrara and Eric S. Lander were three of the 11 inaugural winners announced Feb. 20 by Breakthrough Prize in Life Sciences Foundation founders Sergey Brin, Anne Wojcicki, Mark Zuckerberg, Priscilla Chan and Yuri Milner. The foundation is dedicated to advancing breakthrough research, celebrating scientists and generating excitement about the pursuit of science as a career. Each winner receives a $3 million cash prize to support their continued research.
Cantley, of Weill Cornell Medical College and New York Presbyterian Hospital, is honored for the discovery of PI3-Kinase and its role in cancer metabolism. Ferrara, of the University of California, San Diego, is honored for discoveries in the mechanisms of angiogenesis that led to therapies for cancer and eye diseases. Lander, of the Broad Institute of Harvard and MIT, is honored for the discovery of general principles for identifying human disease genes and enabling their application to medicine through the creation and analysis of genetic, physical and sequence maps of the human genome.
Congratulations from SLAS!
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SLAS2013 keynote presentations by Kroto, Sabine and Toner now available for free at SLAS On-Demand
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Experience Sir Harold Kroto's "Science and Society in the 21st Century" and Charles Sabine's "The Pursuit of Hope and Dignity: Why Every Link in the Medical Chain Matters" from SLAS2013. These thought-provoking keynote presentations are now available at SLAS On-Demand. Access is free and open to SLAS members and non-members alike so invite your colleagues to watch and listen to these highly rated sessions delivered at SLAS2013 in Florida last month. Mehmet Toner's keynote, "Bioengineering and Clinical Applications of the Circulating Tumor Cell Microchip" and the panel presentation, "HTS and Early Drug Discovery in Industry and Academia. Collaboration: Is the Sum Greater Than the Two Parts?" also are available at SLAS On-Demand.
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JBS Online features new manuscripts ahead-of-print
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"Identification of Small-Molecule Inhibitors of the Ribonuclease H2 Enzyme," "Comparison of Fluorigenic Peptide Substrates PL50, SNAPtide, and BoTest A/E for BoNT/A Detection and Quantification: Exosite Binding Confers High-Assay Sensitivity" and "Development of a High-Throughput Fluorescence Polarization DNA Cleavage Assay for the Identification of FEN1 Inhibitors" are among the new manuscripts available only to SLAS Biomolecular Sciences Section members right now at JBS Online.
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We offer the industry’s largest human and ortholog GPCR stable cell line collection and hundreds of customizable options for your functional and binding screening and profiling needs, with the highest quality and fastest turnaround. More>> Email: info@multispaninc.com
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Parker Precision Fluidics offers laboratory solutions enabling precise motion and fluidics control for instrument accuracy. RoHS compliant products optimized for stability, long life, and efficiency.
For more information visit www.parker.com/precisionfluidics or email ppfinfo@parker.com.
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2013 SLAS Asia Conference and Exhibition session spotlight: Translational Medicine Basic Research
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Gaochao Zhou, Ph.D., of MSD (Shanghai) Pharmaceuticals Consultancy and Yao-Chang Xu, Ph.D., of Hansoh Pharmaceutical Group are the co-chairs for this session. Four related areas of interest will be explored: "Study of Nutrition, Lifestyle and Genetic Factors on Metabolic Diseases among Chinese," "Bring Best Oncology Drugs to Cancer Patients: A Mission Possible," "Cancer Translational Research for Targeted Therapy" and "Biomarker in Cancer Drug Development."
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Weigh the substance AND the solvent using Quantos automated dispensing systems from METTLER TOLEDO. Preparing accurate concentrations using gravimetric dosing complies with the latest USP guidelines <841>. It offers the benefits of improved quality of results; enhanced user safety; guaranteed process security; and minimized substance and solvent consumption.
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The INTEGRA VIAFLO 96 is a new 96-channel electronic pipette that enables fast, precise and easy simultaneous transfer of 96 samples.
Fast replication or reformatting of 96 and 384 well plates and high precision transferring of reagents, compounds and solutions to or from microplates is now as easy as pipetting with a standard electronic pipette into a single tube.
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Imagine a multi-mode microplate reader that evolves over time. The system is equipped with spectral absorbance, fluorescence, and luminescence capabilities, while the patented flexible design allows the user to add application-specific cartridges such as HTRF, AlphaScreen, as well as first-in-market SpectraMax® MiniMax™ Imaging Cytometer option all in one compact platform. Learn more →
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JALA podcasts offer unique insight from manuscript authors
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Get behind the scenes and into authors' minds when JALA Podcast Editor David Pechter posts friendly and informative author interviews with each new issue of the Journal of Laboratory Automation. Learn more about the authors, their groundbreaking work and their personal insight on laboratory science and technology.
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Clearing out problem proteins
Bioscience Technology Share
MedicineTreatments for Alzheimer's disease have eluded researchers for decades. A major reason for this is because researchers have not pinned down a clear mechanism for the disease. Without knowing what causes Alzheimer's, researchers have not been successful in developing effective treatment regimens to combat it.
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Selling outcomes: Drugmakers scramble for marketable data on the real-world results of therapies
Chemical & Engineering News Share
In the halls of big drug companies like Pfizer and AstraZeneca walks a new breed of manager that didn't exist just two years ago. With puzzling titles like "vice president of real-world data," they are charged with gathering information on patient outcomes — on how well their products work once a patient leaves the doctor's office or the pharmacy.
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The cradle of the nanoparticle
ScienceDaily Share
A new model facilitates predictions about how nanoparticles form and gives clues about how the process can be controlled. Nanoparticles are versatile harbingers of hope: They can serve as active medical agents or contrast media just as well as electronic storage media or reinforcement for structural materials.
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Starfruit Software/Database Service – You can detect instantly one’s mutation. A Look at Past Mutation Reports May Impact Genetic Counseling. Visit Store to see "Starfruit LIMS"
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We are a pre-clinical CRO specialising in bespoke bioassay development, plate-based compound pharmacology and instrument/reagent validation. Contact us at enquiry@aureliabio.com
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First success in real time observation of process of solubilization of CNT by polymer
Phys.org Share
NIMS researchers have succeeded for the first time in the world in real-time analysis of the "polymer wrapping" process by which polymers (polymers of molecules) wrap around single-walled carbon nanotubes, which are a next-generation material. Carbon nanotubes are a promising new material, which are expected to find diverse applications in the fields of soft electronics suing organic materials, chemical sensors, fuel cells, etc. and the environment-friendly green life sciences.
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Thomson Reuters releases EndNoteSync
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You can now access and manage your EndNote library from anywhere using your iPad. With this new tool and EndNote X6, you can easily sync your EndNote library with your iPad and EndNote Web account, and have the ability to collect, collaborate and create from anywhere. Buy at the iTunes store.
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Discovery of a chemical probe for the L3MBTL3 methyllysine reader domain
Nature Chemical Biology Share
We describe the discovery of UNC1215, a potent and selective chemical probe for the methyllysine (Kme) reading function of L3MBTL3, a member of the malignant brain tumor (MBT) family of chromatin-interacting transcriptional repressors. UNC1215 binds L3MBTL3 with a Kd of 120 nM, competitively displacing mono- or dimethyllysine-containing peptides.
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Ancient fossilized sea creatures yield oldest biomolecules isolated directly from a fossil
Lab Manager Share
Though scientists have long believed that complex organic molecules couldn't survive fossilization, some 350-million-year-old remains of aquatic sea creatures uncovered in Ohio, Indiana, and Iowa have challenged that assumption. The spindly animals with feathery arms — called crinoids, but better known by the plant-like name "sea lily" — appear to have been buried alive in storms during the Carboniferous Period.
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New blood test finds elusive fetal gene problem
NewScientist Share
A new non-invasive blood test for pregnant women could make it easier to catch abnormalities before their child is born. Human cells should have two copies of each chromosome, but sometimes the division is uneven. Existing tests count the fragments of placental DNA in the mother's blood. If the fragments from one chromosome are unusually abundant, it might be because the fetus has an extra copy of that chromosome.
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Controlling crystal polymorphism in organic-free synthesis of Na-zeolites
Journal of the American Chemical Society Share
Controlling polymorphism is critical in areas such as pharmaceuticals, biomineralization and catalysis. Notably, the formation of unwanted polymorphs is a ubiquitous problem in zeolite synthesis. In this study, we propose a new platform for controlling polymorphism in organic-free Na-zeolite synthesis that enables crystal composition and properties to be tailored without sacrificing crystal phase purity.
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Sartorius Biohit presents the Picus, the smallest and lightest electronic pipette that eases your workload and provides accurate and precise results. This unique pipette design features patented electronic tip ejection and an intuitive user interface. The Picus has been presented with the 2012 “Red Dot” design award.
Discover Picus at www.sartorius.com/picus.
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Get results fast with Hamamatsu’s FDSS µCELL, an imaging-based microplate reader. This affordable, simple-to-use reader accommodates 96- or 384-well microplates for kinetic cell-based assays such as GPCR, ion channel, prolyl isomerase, transporter, and light-activated receptor or channel assays. Click here for more info.
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IONFIELD SYSTEMS TipCharger™ system uses high-efficiency plasma technology to renew pipette tips. Organic contaminants such as DNA, RNA and compounds are ionized in seconds, allowing disposable tips to be used over and over again! Watch TipCharger Animation Video and see how 30 seconds can save your lab $250,000 per year.
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