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  Mobile version   RSS   Subscribe   Unsubscribe    SLAS2013   Moving? New job? Let SLAS know.    Mar. 7, 2012



SLAS2013 keynote speaker publishes in Biophysical Journal
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Mehmet Toner, Ph.D., and colleagues explore a new microfluidic device that can isolate target cells much faster than existing devices, offering valuable information for diagnosing and treating disease, in the Feb. 22 issue of Biophysical Journal. Toner is the Helen Andrus Benedict Professor of Surgery (Biomedical Engineering), Harvard-MIT Division of Health Sciences and Technology, Harvard Medical School and Massachusetts General Hospital. More


Last call: JALA special issue on novel drug development and delivery
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JALA Editor-in-Chief Dean Ho, Ph.D., of Northwestern University and Co-Guest Editor Edward Chow, Ph.D., of University of California, San Francisco invite you to submit your abstract by Thursday, March 15. Following abstract selection, final manuscripts must be completed and submitted by Friday, June 1. More

Small automated pipettors perform big
SOLO & SOLOPlus Automated Pipettors are the perfect choice for automating repetitive and time consuming applications. Available in single channel, 8-channel and 12- channel configurations the SOLO handles serial dilutions, kinase assays and next-gen sequencing prep with ease. Multiple deck configurations, accessories and robotics are available. See more at Email

SLAS president shares forward focus
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With a highly successful SLAS2012 just passed, 2012 SLAS President Dave Dorsett talks about next steps toward realizing the SLAS strategic plan, including the formation of the SLAS International Advisory Committee. The focus of this important new leadership group is to provide strategic insight and ensure balanced representation globally. More

Long-Term Storage (LTS) per Study

Starfruit Software/Database Service - LTS per Study. You can control who to use a sample. Visit Store – Starfruit Library to see "Starfruit Sample Locator BIMS"

Congratulations, young scientists!
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SLAS welcomed stellar young scientists from around the world to SLAS2012 in San Diego. This year's winners were Lauren Drowley, AstraZeneca, European Laboratory Robotics Interest Group, United Kingdom; Zafer Gezgin, Rutgers University, Institute of Food Technologists, United States; Brian Cox, University of Toronto, International Society for Stem Cell Research, United States; and Jonas Kühn, EPFL-SV-BSF, MipTec, Switzerland. More


Special interest groups offer targeted networking
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From Academic Drug Discovery to Women Professionals in Science and Technology and Automation Quality Control to Stem Cells, SLAS offers an organized way to discuss challenges and share solutions with other SLAS members through free membership in one or more SLAS special interest groups (SIG). Browse descriptions of the 14 current SIGs to find where you might plug in — or learn how to start a new one! More
Inline Homogeneous ELISA Processing - Assay In, Data Out
The Nexar® System optimized for Homogeneous ELISA processing is fully automated and modular. The system includes inline random access sample storage, liquid handling, incubation, and detection (< 3 minutes/384 array). Achieve high throughput processing, miniaturized reaction volumes in Array Tape™ and true walk-away operation. Contact Douglas Scientific today! MORE
MaxCyte® VLX™ Large Scale Transfection System
The MaxCyte® VLX™ Large Scale Transfection System is specifically designed for extremely large volume transfection and is able to transfect up to 2E11 cells in less than 30 minutes with high cell viability and transfection efficiencies. This system is ideal for rapid, gram scale production of proteins and monoclonal antibodies.
Protect Your Automation with Alpillo® from ALPAQUA®
Alpillo® microplate cushions from ALPAQUA® are designed to enhance automated precision pipetting. Integrated spring technology allows for touch-off dispensing and complete aspiration of every microliter of precious samples and reagents from SBS standard microplates. Protect your instruments & consumables and eliminate troublesome tip crashes & head contamination - all while improving pipetting consistency.


NMR detection of pH-dependent histidine—water proton exchange reveals conduction mechanism of transmembrane proton channel
Journal of the American Chemical Society    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The acid-activated proton channel formed by the influenza M2 protein is important for the life cycle of the virus. A single histidine, His37, in the M2 transmembrane domain (M2TM) is responsible for pH activation and proton selectivity of the channel. Recent studies suggested three models for how His37 mediates proton transport: a shuttle mechanism involving His37 protonation and deprotonation, a H-bonded imidazole–imidazolium dimer model and a transporter model involving large protein conformational changes in synchrony with proton conduction. More

Computational redesign of a mononuclear zinc metalloenzyme for organophosphate hydrolysis
Nature Chemical Biology    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The ability to redesign enzymes to catalyze noncognate chemical transformations would have wide-ranging applications. We developed a computational method for repurposing the reactivity of metalloenzyme active site functional groups to catalyze new reactions. Using this method, we engineered a zinc-containing mouse adenosine deaminase to catalyze the hydrolysis of a model organophosphate with a catalytic efficiency (kcat/Km) of ∼104 M−1 s−1 after directed evolution. More

Get Connected to Laboratory Science at Pittcon 2012
If you are a scientist or researcher looking for the latest innovations in laboratory equipment–then Pittcon 2012, the world’s largest annual conference and expo for lab science, is a must attend event. Register now at

Squeezing polymers produces chemical energy but raises doubts about implant safety
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In a new study, Northwestern University scientists turned to squeezed polymers and free radicals in a search for new energy sources. They found incredible promise but also some real problems. Their report is published by the journal Angewandte Chemie. The researchers demonstrated that radicals from compressed polymers generate significant amounts of energy that can be used to power chemical reactions in water. More


Washington U. to offer free exome sequencing for rare diseases
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Washington University School of Medicine in St. Louis plans to provide free exome sequencing for 99 patients suffering from rare disorders in an effort to discover genetic factors that may be causing these diseases. The Rare99X Clinical Exome Challenge project will work with patient groups to study patients with some of the nearly 7,000 rare diseases that affect an estimated 25 million Americans. More

Innovation³ from TTP Labtech

3 innovative products launched at SLAS Booth 914:

• arktic: compact automated biobanking
• aequus: non-contact liquid level monitoring
• mosquito HV: cost-saving serial dilutions.

The stealth sodium revolution
Lab Manager    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Researchers with the U.S. Departments of Agriculture and Health and Human Services have teamed up for HHS's sodium surveillance efforts. The National Institute of Medicine, part of the National Academies, is also involved and has called on the Food and Drug Administration to set mandatory national standards for the sodium content in foods. More

Experimental viral evolution to specific host MHC genotypes reveals fitness and virulence trade-offs in alternative MHC types
National Academy of Sciences    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The unprecedented genetic diversity found at vertebrate MHC (major histocompatibility complex) loci influences susceptibility to most infectious and autoimmune diseases. The evolutionary explanation for how these polymorphisms are maintained has been controversial. One leading explanation, antagonistic coevolution, postulates a never-ending molecular arms race where pathogens evolve to evade immune recognition by common MHC alleles, which in turn provides a selective advantage to hosts carrying rare MHC alleles. More


Making memories: How 1 protein does it
Science Daily    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Studying tiny bits of genetic material that control protein formation in the brain, Johns Hopkins scientists say they have new clues to how memories are made and how drugs might someday be used to stop disruptions in the process that lead to mental illness and brain wasting diseases. The report was published in the March 2 issue of Cell. More

A wirelessly controlled pharmacy dispenses drugs from within your abdomen
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In the future, implantable computerized dispensaries will replace trips to the pharmacy or doctor's office, automatically leaching drugs into the blood from medical devices embedded in our bodies. These small wireless chips promise to reduce pain and inconvenience, and they'll ensure that patients get exactly the amount of drugs they need, all at the push of a button. More

Flexible, Reliable Lab Automation Solutions

Whether your lab is manual, semi-automated or fully automated, FlexLink has flexible conveyor systems and solutions that fit perfectly where space is limited and close machine interface is required.

Dental pulp stem cells transformed by 'bad breath' chemical
eBio News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Japanese scientists have found that the odorous compound responsible for halitosis — otherwise known as bad breath — is ideal for harvesting stem cells taken from human dental pulp. In a study published in the Journal of Breath Research, researchers showed that hydrogen sulphide increased the ability of adult stem cells to differentiate into hepatic (liver) cells, furthering their reputation as a reliable source for future liver-cell therapy. More

A little mass spec goes a long way
Genetic Engineering & Biotechnology News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Transition metal complexes catalyze many important reactions that are employed in medicine, materials science and energy production. Although high-throughput methods for the discovery of catalysts that would mirror related approaches for the discovery of medicinally active compounds have been the focus of much attention, these methods have not been sufficiently general or accessible to typical synthetic laboratories to be adopted widely. More


Shale boom in full swing for North American petrochemical industry
Chemical & Engineering News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Shale is forcing North American petrochemical executives to unlearn much of what they thought they knew about their industry. And given that they are near the beginning of what is likely to be a long, prosperous period, they are more than happy to change their outlook. Experiences early in the previous decade taught executives that their reliance on raw materials derived from natural gas to make ethylene put them at a cost disadvantage to the areas of the world that use petroleum-derived naphtha. More

Even mild concussions can cause lingering symptoms
The Associated Press via Bioscience Technology    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Children with even relatively mild concussions can have persistent attention and memory problems a year after their injuries, according to a study that helps identify which kids may be most at risk for lingering symptoms. In most kids with these injuries, symptoms resolve within a few months but the study results suggest that problems may linger for up to about 20 percent, said study author Keith Owen Yeates. More

RapidFire High-throughput Mass Spectrometry Systems

Agilent Technologies’ RapidFire is an SPE-based solution that enables detection of native compounds by mass spec. Requiring no labels or surrogates, it enables the screening of intractable or challenging targets which are not amenable to fluorescence or luminescence. Sample throughput is 10x faster than conventional MS screening methods. MORE
Choose the new Standard in Lab Automation - SiLA
How do you like straightforward integration and adaptation of systems at lower costs? Using SiLA the replacement cost of existing integrated devices is significantly reduced. System integrators have greater independence in the choice of devices and compatibility problems with device drivers are a thing of the past. infoteam knows how.

You want to know more? Contact infoteam Software!
Labcyte Introduces Dynamic Fluid Analysis™
Labcyte released a novel software algorithm that enables a greater range of fluid types to be automatically transferred with acoustic energy. Dynamic Fluid Analysis™ enables the Echo® liquid handling systems to adapt to fluid properties changes such as surface tension and viscosity, and adjusts sound energy in real time with no operator intervention required.


Application Engineer II
Broad Institute
USA – MA – Cambridge

Drug Development Scientist
Cedars-Sinai Medical Center
USA – CA – Los Angeles

Robotic Integration Specialist
USA – CA – Sunnyvale

More jobs at SLAS Career Connections

FSSI: Advanced Compound Management Services
Focused on Outsourced Materials Management and Sample Preparation Services, FSSI supports Compound Management, Research and Discovery Screening, and Chemistry. FSSI performs Sample Reformatting and Full Repository Services with on-demand 24-48 hour delivery. FSSI offers diversity screening libraries, pre-weighed building blocks in custom aliquots, full preparative purification, and high-throughput analysis.
EasyHandling: Cut Engineering Time, Costs
EasyHandling makes Mechatronics easier and faster than ever, with high-performance mechanical technologies and our new EasyWizard programming tool. Cut engineering time, effort & cost by up to 80%. EasyHandling is perfect for Lab applications—ranging from test tube pick-and-place and medical product packaging to hands-off inspection of hazardous materials.
Get your free automation consultation
Astech Projects launch new turnkey approach to automation at SLAS! Composed of four key steps – consultation & proposal, concept design study, proof of concept, and detailed design, manufacture and testing – Astech currently offers the initial consultation & proposal free of charge. Apply for yours today.







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Certified UPS’s to protect your laboratory’s critical instrumentation and resolve current and potential power issues.


The most comprehensive LIMS solution

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Industry-renowned sample management software

13 of 20 top pharma/biotech companies have chosen Titian’s modular Mosaic™ software to control their sample storage/preparation. Find out why.

JALA: Leading Peer-Reviewed Journal

JALA is a multi-disciplinary international forum devoted to the advancement of technology in the laboratory.

The SLAS Electronic Laboratory Neighborhood

It's new. It's newsy. And it's available now. Check out this interactive e-zine today.

SLAS Point-to-Point
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