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Practice Social Distancing; Catch up on the Latest Life Sciences and Tech Content Online
SLAS
With the recent cancellations and postponements of global educational events due to the COVID-19 pandemic, now is a good time to catch up with the wealth of content on APPLIED. The online educational platform currently has a wide variety of recorded sessions from past conferences and symposia, webinars and podcasts with a good portion of modules available for free. Log in and choose from:
- The SLAS2020 Conference Recordings featuring 95 scientific sessions, both keynotes, three Ignite Panel Discussions, four Ignite Academic Collaboration Presentations and 14 SLAS Ignite Award finalist presentations from Innovation AveNEW participants;
- SLAS2020 Solutions Spotlight Presentations featuring 20-minute talks by selected exhibitors showcasing their cutting-edge laboratory research and technology solutions;
- On the lighter side, New Matter: Inside the Minds of SLAS Scientists podcasts with SLAS Scientific Director Mike Tarselli;
- SLAS Discovery (new!) and SLAS Technology podcast series;
- past recordings from the 2019 Americas and European Sample Management, AI in Process Automation and Advanced 3D Human Models and High-Content Analysis Symposia;
- and much more!
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SLAS
If you aren’t familiar with SLAS membership or haven’t revisited our benefits in the last year, it’s time to take a closer look. Our SLAS Premier Membership benefits have expanded to include access to discounts in APPLIED and exclusive members-only groups in CONNECTED, while continuing to offer deep discounts on all global events and symposia. If full membership isn’t in the budget right now, consider our new $25 Networking Membership, which provides full member access to network with colleagues through CONNECTED.
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Black Dog offers quality refurbished FLIPR® and FLIPRTETRA® fluorescence readers for your high throughput applications. Take
advantage of our 15-Year Anniversary Promotion: Save 15% and get a 15-Month Warranty*. Affordable leasing options
available. *Warranty restrictions apply; contact Black Dog.
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Thermo Scientific
The Thermo Scientific™ Orbitor™ RS2 microplate mover is a collaborative bench-top mover that provides unbeatable reliability and improved process efficiency. It’s innovative bi-directional telescoping arm coupled with it’s expansive 360° workspace provide exceptional reach and precision, making the Orbitor RS2 your trusted laboratory productivity partner.
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CRISPR System's Optimized Guides Can Target RNA, Including Coronavirus RNA
Genetic Engineering & Biotechnology News
Once overshadowed by DNA-targeting CRISPR systems, RNA-targeting CRISPR systems are stepping into the light. What’s more, RNA-targeting CRISPR systems are advancing on important applications for which they are uniquely well suited. For example, they can silence gene expression at the transcriptional level, which is advantageous if the corresponding targets at the genomic level are hard to access. Also, RNA-targeting CRISPR systems can be effective in targeting RNA viruses such as the coronaviruses or influenza viruses.
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Scientists Identify Potential Targets for Immune Responses to SARS-CoV-2
Lab Manager
Within two months, SARS-CoV-2, a previously unknown coronavirus, has raced around globe, infecting over a 100,000 people with numbers continuing to rise quickly. Effective countermeasures require helpful tools to monitor viral spread and understand how the immune system responds to the virus.
Publishing in the March 16, 2020, online issue of Cell, Host and Microbe, a team of researchers at La Jolla Institute for Immunology, in collaboration with researchers at the J. Craig Venter Institute, provides the first analysis of potential targets for effective immune responses against the novel coronavirus.
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Hydroxide Based Integrated CO2 Capture from Air and Conversion to Methanol
Journal of the American Chemical Society
The first example of an alkali hydroxide-based system for CO2 capture and conversion to methanol has been established. Bicarbonate and formate salts were hydrogenated to methanol with high yields in a solution of ethylene glycol. In an integrated one-pot system, CO2 was efficiently captured by an ethylene glycol solution of the base and subsequently hydrogenated to CH3OH at relatively mild temperatures (100–140 °C) using Ru-PNP catalysts. The produced methanol can be easily separated by distillation.
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Say hello to the BioXp™ 3200 system and say goodbye to service labs and spending days building DNA on the bench. Build up to 32 complex constructs from 300 bp to 3600 bp with multiple fragments and vectors, overnight. Build better. Build faster. Build cheaper.
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Newly Discovered 'Magic Methyl' Reaction Could Turbocharge the Potency of Some Drugs
Science Magazine
For years, drug discovery chemists have struggled to streamline a process that can boost a drug’s potency up to 2000-fold: “magic methylation.” The reaction sweeps out single hydrogen atoms and replaces them with methyl groups—reshaping the drug molecule to more easily interact with its biological targets. But carrying out this sleight of hand is so difficult that few researchers even try. Now, a team of chemists reports it has created a new catalyst that performs this delicate exchange with ease on a wide variety of druglike molecules, an advance that could lead to novel treatments for everything from cancer to infectious diseases.
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Solving a Mystery in 126 Dimensions
Science Daily
One of the fundamental mysteries of chemistry has been solved by Australian scientists — and the result may have implications for future designs of solar cells, organic light-emitting diodes and other next gen technologies.
Ever since the 1930s debate has raged inside chemistry circles concerning the fundamental structure of benzene. It is a debate that in recent years has taken on added urgency, because benzene is the smallest molecule that can be used in the production of opto-electronic materials, which are revolutionising renewable energy and telecommunications tech.
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Mechanical Chirality Gives New Shape to Catalysis
Chemical & Engineering News
Researchers in the UK have used a mechanically planar chiral rotaxane as the basis for an enantioselective gold catalyst. Stephen Goldup and Andrew Heard at the University of Southampton say their work is a proof of concept that mechanical bonds can be used to build “pockets” for selective synthesis akin to those found in enzymes. Heard started by building and separating two mechanically chiral rotaxanes. Rotaxanes are mechanically interlocked molecules in which a macrocycle is threaded onto a dumbbell-shaped compound or axle.
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Amplification and Imaging of MicroRNA as a Biomarker to Detect Tumor Development
Phys.org
A good indicator of dysregulation in live cells is a change in their RNA expression. MicroRNA (miRNA), a special type of RNA, is considered a biomarker for carcinogenic cells. A team of scientists from China has found a way to amplify miRNA in live tumor cells for bioimaging. As they report in the journal Angewandte Chemie, their assay is based on a robust cellular autocatalytic biocircuit triggered by synthetic DNA and nanoparticles.
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Job Seekers: Post your résumé and sign up for new job alerts by keyword.
Employers: Search résumés, post an open position, internship or post-doc opportunity. SLAS Premier and Corporate Members get a discount on all new job postings.
Automation Platform Development Specialist/Spécialiste développement de plateforme d'automatisation
Charles River
CAN – QC – Senneville
Postdoctoral Associate in Cancer Bioengineering
University of Pittsburgh
US – PA – Pittsburgh
Postdoctoral Research Associate
Rice University
US – TX – Houston
Search Jobs at SLAS Career Connections
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