This message contains images. If you don't see images, click here to view. Advertise in this news brief. Advertisement Text version   RSS   Subscribe   Unsubscribe   Archive   Media Kit March 23, 2016 SLAS.org    SLAS2017    Moving? New job? Let SLAS know.       Advertisement Advertisement Advertisement Advertisement   Advertisement March 24 (Tomorrow!) SLAS Webinar: The SmartLab of the Future — Benchtop Lab Automation with the PetriJet and NutriJet Platforms SLAS     Share    Felix Lenk, Ph.D., Technische Universität Dresden, describes the PetriJet platform, a compact device for the automated handling of culture dishes in batches of 20 or continuously. Together with exchangeable processing stations, nearly all tasks associated with culture dishes like identification, filling and imaging can be effectively automated. NutriJet provides a lab with a fully automated solution for medium composition right from the container of the ingredient manufacturer and is fully GMP compliant. The March 24 webinar, presented by JALA and JBS, the official journals of SLAS, is free to SLAS dues-paying members. More Advertisement NEW! JALA Special Issue on High-Throughput Imaging Technologies SLAS    Share    Nine peer-reviewed original research reports from Finland, France, Italy, Hungary, Spain and the United States present advancements in imaging technology that improve both clinical and research-based imaging needs, particularly focusing on advancements that integrate automation and high-throughput into traditional and emerging imaging applications. Many advances in imaging technology that allow for automated high-throughput imaging also improve the implementation of complex diagnostic assays in the clinic by lowering the cost per assay and reducing the need for specialized training to perform diagnostic tests, having a great impact on improved infectious diseases care. SLAS Laboratory Automation Section members and JALA subscribers can view the issue online now. More Advertisement Tecan booth talks at SLAS2016 are now available! JALA Special Issue Call for Papers: Micro- and Nanotechnologies for Quantitative Biology and Medicine SLAS    Share    Guest Editor Somin Eunice Lee, Ph.D., of the University of Michigan (USA) invites proposals (abstracts) of original, high-quality research and review papers for a special issue on quantitative enabling micro- and nanotechnologies. Share expertise and recent research in micro- and nanotechnologies at the interfaces of physics, chemistry, engineering, biology and medicine. Areas of interest include microfluidics, microfabrication, bioMEMS, nanofabrication, bionanotechnology, nanomedicine, diagnostics, point-of-care, tissue engineering and imaging. Abstracts for this special issue are due April 1. JALA and JBS also are accepting manuscript proposals for four other special issues: Cancer Metabolism (JBS manuscript proposals due April 1) 3D Cell Culture, Drug Screening and Optimization (JBS manuscript proposals due June 1) Personalized and Precision Medicine (JALA manuscript proposals due June 1) Quantitative Imaging in Life Sciences and Biomedical Research (JALA manuscript proposals due April 1, 2017) More Advertisement ACCELERATE YOUR SAMPLE PREP See how researchers are accelerating their research with the Agilent Bravo Automated Sample Prep Platform. On-Demand at SLAS.org: High-Throughput Screening of Metagenomic DNA Libraries SLAS    Share    In his SLAS2016 Assay Development and Screening Track presentation, Louis Cohen, Icahn School of Medicine at Mount Sinai, USA, details his work examining 3,000 megabases of metagenomic DNA cloned from three phenotypically distinct patients for effectors that activate NF-κB, a transcription factor known to play a central role in mediating responses to environmental stimuli. Cohen's study shows the utility of functional metagenomics for identifying potential mechanisms used by commensal bacteria for host interactions and outlines a functional metagenomics-based pipeline for the systematic identification of diverse commensal bacteria effectors that impact host cellular functions. It is one of seven presentations recorded at SLAS2016 for convenient, on-demand viewing by SLAS dues-paid members and SLAS2016 full conference participants. More Advertisement JBS April: Focused Screening Identifies Evoxine as a Small Molecule That Counteracts CO2-Induced Immune Suppression SLAS    Share    Do non-neuronal cells respond to molecular CO2 via specific pathways, independent of pH? Are these pathways evolutionarily conserved? Can these pathways be targeted pharmacologically? A new research report published in the April 2016 issue of the Journal of Biomolecular Screening (JBS) sheds light on these interesting questions, which have been a focus of a close collaboration at Northwestern University. More Job Seekers and Employers Connect via SLAS Career Connections SLAS    Share    Visit this targeted employment exchange regularly to keep up to date with opportunities. Job seekers can post resumes and browse job openings for free, including recent posts like principal scientist/cell biology and imaging, director of innovation, senior automation specialist (robotics)/antibody engineering and automation engineer. Employers can find new talent by reviewing posted resumes for free and attract new talent by posting job openings for a fee. Note: SLAS Corporate Members receive a 50% discount on job postings. More Advertisement SpectraMax i3x Multi-Mode Microplate Reader The injector-ready SpectraMax® i3x Platform from Molecular Devices is a multi-mode microplate reader system that evolves with your future needs and offers an unlimited breadth of application possibilities. The SpectraMax i3x gives you the flexibility of modular upgrades without the need for service engineers or costly downtime. Advertisement Welcome to RAD Source Since 1997 Rad Source Technologies has been the expert in providing renewable, non-isotope, ionizing radiation replacements for self-shielded gamma irradiators. Currently, there are over 300 renowned hospital, university, and pharmaceutical research institutions using Rad Source X-ray technology. To find out more about our equipment, select your application and you will find equipment specifications, literature references, white papers, training videos, discussion forums, as well as other helpful info. Advertisement Fully automate your genomics workflow The Fragment Analyzer INFINITY is the only parallel capillary electrophoresis instrument capable of complete integration into your robotic automation system. Fully compatible with all the high quality kits developed for the Fragment Analyzer, the Fragment Analyzer INFINITY can run over 2400 samples a day without human intervention. Molecular Lifting, Twisting, and Curling during Metal-Assisted Polycyclic Hydrocarbon Dehydrogenation Journal of the American Chemical Society    Share    The atomistic understanding of the dissociation mechanisms for large molecules adsorbed on surfaces is still a challenge in heterogeneous catalysis. This is especially true for polycyclic aromatic hydrocarbons, which represent an important class of organic compounds used to produce novel graphene-based architectures. Here, we show that coronene molecules adsorbed on Ir(111) undergo major conformational changes during dissociation. More Advertisement Important factors to Consider for Thermal Shift Assays Download the Overcoming Technical Challenges in Cell-Based High Throughput Screens Whitepaper Scientists Develop New Technique for Imaging Cells and Tissues Under the Skin Lab Manager    Share    Scientists have many tools at their disposal for looking at preserved tissue under a microscope in incredible detail, or peering into the living body at lower resolution. What they haven't had is a way to do both: create a three-dimensional real-time image of individual cells or even molecules in a living animal. Now, Stanford University scientists have provided the first glimpse under the skin of a living animal. More Advertisement Become a Lab Superhero! The Mantis will revolutionize your workflow for applications including NGS sample prep, qPCR, assay development, and cellular assays. Automation made simple. Advertisement Cloud, Consulting, and Custom Services, All In One. Scigilian is a software company specializing in offering solutions to the problems encountered in pharmaceutical research, biotechnology, and contract research. Trusted, from large pharma to small CRO. New Way to Harvest Stem Cells Better for Donors Bioscience Technology    Share    Australian scientists have developed a new method for harvesting stem cells, which is less invasive and reduces side effects for donors. For bone marrow transplantation, stem cells are routinely harvested from healthy donors and used to treat patients with cancers including leukemia. Current harvesting methods take a long time and require injections of a growth factor to boost stem cell numbers. This often leads to side effects. More Measuring Chemistry: Local Fingerprint of Hydrogen Bonding Captured in Experiments Science Daily    Share    Molecules are composed of atoms that maintain specific intervals and angles between one another. However, the shape of a molecule can change, for example, through proximity to other molecules, external forces and excitations, and also when a molecule makes a chemical connection with another molecule, for instance in a chemical reaction. A very useful concept in describing the changes that are possible in molecules is the use of what are called "potential surfaces" or energy landscapes. More Advertisement How to Store Microbiome Samples Without Losing or Altering Diversity The Scientist    Share    In the last decade or so, researchers have spent billions of dollars categorizing the microbes that populate sites as disparate as the human body, soil, and the oceans. Much of what we know about these different microbiomes has been determined using increasingly sophisticated next-generation sequencing technologies. For instance, scientists typically gauge a sample's microbial diversity by performing high-throughput sequencing on the gene coding for 16S rRNA, a component of the small subunit of bacterial ribosomes. More For Stem Cells, Half a Genome Is Better Than None Genetic Engineering & Biotechnology News    Share    Scientists from The Hebrew University of Jerusalem, Columbia University Medical Center, and The New York Stem Cell Foundation Research Institute say they succeeded in generating a new type of embryonic stem cell that carries a single copy of the human genome instead of the two copies typically found in normal stem cells. The scientists reported their findings ("Derivation and Differentiation of Haploid Human Embryonic Stem Cells") in Nature. More Advertisement KMC Systems Engineering & Manufacturing KMC Systems provides contract engineering and manufacturing services to leading and emerging OEMs. As a trusted outsourcing partner for 35 years, KMC Systems develops, designs and manufactures cutting-edge, full-system instrumentation for the medical and life science markets. Visit us online and download our brochure to learn more about KMC Systems. Advertisement The Concept Is Simple We work with scientists to design and develop new, innovative tools for biological, chemical, and materials research, both in basic studies and pharmaceutical and industrial applications. We know research, we know assay development, and we know tools development. Learn More Advertisement Sample Screening from your Compound The comPOUND system comprises a high-density sample storage unit and an additional suite of specialized delivery and processing modules to enable easy integration into any compound management or screening system. Chemists Develop an Ultra-Sensitive Test for Cancers, HIV Phys.org    Share    A common theme in medicine is that detecting a disease early on can lead to more effective treatments. This relies partly on luck that the patient gets screened at the right time, but more important is that the testing techniques are sensitive enough to register the minuscule hints that diseases leave in the blood stream. A new technique developed by a team of chemists at Stanford has shown promise to be thousands of times more sensitive than current techniques in lab experiments. More Forecasting Liver Toxicity Before the Damage Is Done Chemical & Engineering News    Share    The liver takes the brunt of the job of clearing drugs from the body, subjecting the organ to a significant toxicity risk. One of the biggest challenges in drug discovery is figuring out which drug candidates are likely to harm the liver before testing the agents in humans. Now, researchers have developed a computational model that compares a drug candidate to those known to cause liver damage and predicts whether the novel drug is likely to do the same. More Advertisement Senior Automation Specialist (Robotics), Antibody Engineering Genentech US – CA – South San Francisco Automation Engineer AbbVie US – MA – Worcester Bio-Instrumentation Engineer, BioFoundry Berkeley Lights, Inc. USA – CA – Emeryville Search Jobs at SLAS Career Connections   SLAS Point-to-Point Colby Horton, Vice President of Publishing, 469.420.2601 Download media kit Dennis Hall, Executive Editor, 469.420.2656    Contribute news This edition of SLAS Point-to-Point was sent to ##Email##. To unsubscribe from receiving SLAS Point-to-Point, click here. To unsubscribe from all SLAS e-mail communications, please click here. Did someone forward this edition to you? Subscribe here — it's free! 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