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Text version   RSS   Subscribe   Unsubscribe   Archive   Media Kit March 23, 2016

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March 24 (Tomorrow!) SLAS Webinar: The SmartLab of the Future — Benchtop Lab Automation with the PetriJet and NutriJet Platforms
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Felix Lenk, Ph.D., Technische Universität Dresden, describes the PetriJet platform, a compact device for the automated handling of culture dishes in batches of 20 or continuously. Together with exchangeable processing stations, nearly all tasks associated with culture dishes like identification, filling and imaging can be effectively automated.

NutriJet provides a lab with a fully automated solution for medium composition right from the container of the ingredient manufacturer and is fully GMP compliant. The March 24 webinar, presented by JALA and JBS, the official journals of SLAS, is free to SLAS dues-paying members.
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NEW! JALA Special Issue on High-Throughput Imaging Technologies
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Nine peer-reviewed original research reports from Finland, France, Italy, Hungary, Spain and the United States present advancements in imaging technology that improve both clinical and research-based imaging needs, particularly focusing on advancements that integrate automation and high-throughput into traditional and emerging imaging applications.

Many advances in imaging technology that allow for automated high-throughput imaging also improve the implementation of complex diagnostic assays in the clinic by lowering the cost per assay and reducing the need for specialized training to perform diagnostic tests, having a great impact on improved infectious diseases care. SLAS Laboratory Automation Section members and JALA subscribers can view the issue online now.
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JALA Special Issue Call for Papers: Micro- and Nanotechnologies for Quantitative Biology and Medicine
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Guest Editor Somin Eunice Lee, Ph.D., of the University of Michigan (USA) invites proposals (abstracts) of original, high-quality research and review papers for a special issue on quantitative enabling micro- and nanotechnologies. Share expertise and recent research in micro- and nanotechnologies at the interfaces of physics, chemistry, engineering, biology and medicine. Areas of interest include microfluidics, microfabrication, bioMEMS, nanofabrication, bionanotechnology, nanomedicine, diagnostics, point-of-care, tissue engineering and imaging. Abstracts for this special issue are due April 1.

JALA and JBS also are accepting manuscript proposals for four other special issues:
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On-Demand at SLAS.org: High-Throughput Screening of Metagenomic DNA Libraries
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In his SLAS2016 Assay Development and Screening Track presentation, Louis Cohen, Icahn School of Medicine at Mount Sinai, USA, details his work examining 3,000 megabases of metagenomic DNA cloned from three phenotypically distinct patients for effectors that activate NF-κB, a transcription factor known to play a central role in mediating responses to environmental stimuli.

Cohen's study shows the utility of functional metagenomics for identifying potential mechanisms used by commensal bacteria for host interactions and outlines a functional metagenomics-based pipeline for the systematic identification of diverse commensal bacteria effectors that impact host cellular functions. It is one of seven presentations recorded at SLAS2016 for convenient, on-demand viewing by SLAS dues-paid members and SLAS2016 full conference participants.
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JBS April: Focused Screening Identifies Evoxine as a Small Molecule That Counteracts CO2-Induced Immune Suppression
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Do non-neuronal cells respond to molecular CO2 via specific pathways, independent of pH? Are these pathways evolutionarily conserved? Can these pathways be targeted pharmacologically?

A new research report published in the April 2016 issue of the Journal of Biomolecular Screening (JBS) sheds light on these interesting questions, which have been a focus of a close collaboration at Northwestern University. More


Job Seekers and Employers Connect via SLAS Career Connections
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Visit this targeted employment exchange regularly to keep up to date with opportunities. Job seekers can post resumes and browse job openings for free, including recent posts like principal scientist/cell biology and imaging, director of innovation, senior automation specialist (robotics)/antibody engineering and automation engineer. Employers can find new talent by reviewing posted resumes for free and attract new talent by posting job openings for a fee. Note: SLAS Corporate Members receive a 50% discount on job postings. More


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Molecular Lifting, Twisting, and Curling during Metal-Assisted Polycyclic Hydrocarbon Dehydrogenation
Journal of the American Chemical Society    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The atomistic understanding of the dissociation mechanisms for large molecules adsorbed on surfaces is still a challenge in heterogeneous catalysis. This is especially true for polycyclic aromatic hydrocarbons, which represent an important class of organic compounds used to produce novel graphene-based architectures. Here, we show that coronene molecules adsorbed on Ir(111) undergo major conformational changes during dissociation. More


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Scientists Develop New Technique for Imaging Cells and Tissues Under the Skin
Lab Manager    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Scientists have many tools at their disposal for looking at preserved tissue under a microscope in incredible detail, or peering into the living body at lower resolution. What they haven't had is a way to do both: create a three-dimensional real-time image of individual cells or even molecules in a living animal. Now, Stanford University scientists have provided the first glimpse under the skin of a living animal. More


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New Way to Harvest Stem Cells Better for Donors
Bioscience Technology    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Australian scientists have developed a new method for harvesting stem cells, which is less invasive and reduces side effects for donors. For bone marrow transplantation, stem cells are routinely harvested from healthy donors and used to treat patients with cancers including leukemia. Current harvesting methods take a long time and require injections of a growth factor to boost stem cell numbers. This often leads to side effects. More


Measuring Chemistry: Local Fingerprint of Hydrogen Bonding Captured in Experiments
Science Daily    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Molecules are composed of atoms that maintain specific intervals and angles between one another. However, the shape of a molecule can change, for example, through proximity to other molecules, external forces and excitations, and also when a molecule makes a chemical connection with another molecule, for instance in a chemical reaction. A very useful concept in describing the changes that are possible in molecules is the use of what are called "potential surfaces" or energy landscapes. More


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How to Store Microbiome Samples Without Losing or Altering Diversity
The Scientist    Share    Share on FacebookTwitterShare on LinkedinE-mail article
In the last decade or so, researchers have spent billions of dollars categorizing the microbes that populate sites as disparate as the human body, soil, and the oceans. Much of what we know about these different microbiomes has been determined using increasingly sophisticated next-generation sequencing technologies. For instance, scientists typically gauge a sample's microbial diversity by performing high-throughput sequencing on the gene coding for 16S rRNA, a component of the small subunit of bacterial ribosomes. More


For Stem Cells, Half a Genome Is Better Than None
Genetic Engineering & Biotechnology News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Scientists from The Hebrew University of Jerusalem, Columbia University Medical Center, and The New York Stem Cell Foundation Research Institute say they succeeded in generating a new type of embryonic stem cell that carries a single copy of the human genome instead of the two copies typically found in normal stem cells. The scientists reported their findings ("Derivation and Differentiation of Haploid Human Embryonic Stem Cells") in Nature. More


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Chemists Develop an Ultra-Sensitive Test for Cancers, HIV
Phys.org    Share    Share on FacebookTwitterShare on LinkedinE-mail article
A common theme in medicine is that detecting a disease early on can lead to more effective treatments. This relies partly on luck that the patient gets screened at the right time, but more important is that the testing techniques are sensitive enough to register the minuscule hints that diseases leave in the blood stream. A new technique developed by a team of chemists at Stanford has shown promise to be thousands of times more sensitive than current techniques in lab experiments. More


Forecasting Liver Toxicity Before the Damage Is Done
Chemical & Engineering News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The liver takes the brunt of the job of clearing drugs from the body, subjecting the organ to a significant toxicity risk. One of the biggest challenges in drug discovery is figuring out which drug candidates are likely to harm the liver before testing the agents in humans. Now, researchers have developed a computational model that compares a drug candidate to those known to cause liver damage and predicts whether the novel drug is likely to do the same. More


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Career


Senior Automation Specialist (Robotics), Antibody Engineering
Genentech
US – CA – South San Francisco

Automation Engineer
AbbVie
US – MA – Worcester

Bio-Instrumentation Engineer, BioFoundry
Berkeley Lights, Inc.
USA – CA – Emeryville

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