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Students, graduate students, post-doctoral associates and junior faculty may apply for travel awards. 56 awarded for SLAS2015.
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SLAS Webinar March 31: HELM — Setting the Standard for Biomolecular Data Exchange
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The increased focus on biotherapeutics R&D in the biopharmaceutical industry reveals a gap in the ability of traditional informatics tools to deal with complex biologic entities in a natural and precise manner.
HELM (Hierarchical Editing Language for Macromolecules) allows biotherapeutics researchers to define these entities without ambiguity, just as chemists have been able to do for small molecules.
Pfizer’s Tianhong Zhang outlines the HELM standard and the reference implementation, its origin and use at Pfizer, the Pistoia Alliance HELM project that has transitioned the technology into open source and the emerging HELM ecosystem in the SLAS Webinar, free to dues-paid SLAS members. Not yet a member? Join today.
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JALA Special Issue: Microengineered Cell- and Tissue-Based Assays for Drug Screening and Toxicology Applications
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Now at JALA Online, part one of this two-part special issue by guest editors Dan Huh of the Univ. of Pennsylvania and Deok-Ho Kim of the Univ. of Washington surveys some of the most significant advances in this important field.
The two-part collection of 17 original research reports and reviews shares knowledge and insight that can benefit a wide range of communities in pharmaceutical and toxicology research.
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JBS Abstracts Due April 10: Advances in Mass Spectrometry within Drug Discovery
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Guest Editors Ian Wilson and Jonathan Wingfield seek proposals for manuscripts that address throughput issues for mass spectrometry detection systems, novel analytical mass spectrometry techniques, advances in ionization sources and mass spectrometry-based methods for determining drug protein and receptor binding. SLAS members and nonmembers alike are invited to submit proposals. If invited (notification by April 14), final manuscripts will be due July 1.
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Students: SLAS is Now Accepting Tony B. Academic Travel Award Applications for SLAS2016
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"As a global Society, we are committed to fostering continued scientific innovation and cultivating the next generation of professionals who will drive that innovation, which will ultimately result in better, more accurate research," says SLAS President Dean Ho. Applications are due Aug. 3, 2015.
Tony B. awardees receive airfare, full conference registration, hotel accommodations and the opportunity to participate fully in SLAS2016, Jan. 23-27 in San Diego, CA, the premier conference for laboratory science and technology professionals. At SLAS2015, 56 students from 12 countries earned invitations to present their scientific achievements through the Tony B. program.
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Now at JBS Online: Biologics Come of Age
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The April issue of the Journal of Biomolecular Screening explores Therapeutic Antibody Discovery and Development.
Organized by Rob Howes of MedImmune and Joseph McGivern of Amgen, the 12 original research reports, reviews and technical notes in this special issue address various aspects and challenges associated with the discovery, development and manufacture of biologics.
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Job Seekers and Employers Connect via SLAS Career Connections
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Visit this targeted employment exchange regularly to keep up to date with opportunities. Job seekers can post resumes and browse job openings for free. Employers can find new talent by reviewing posted resumes for free and attract new talent by posting job openings for a fee. Laboratory automation engineer, research informatics and applications specialist, analytical development director and assistant professor biomedical sciences are a few of the life science jobs listed in SLAS Career Connections currently.
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10 Encore Presentations from SLAS2015 Now Available to SLAS Members
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10 podium presentations recorded at SLAS2015 are available to dues-paying SLAS members for on demand access. Included among this high-profile collection is the 2015 SLAS Innovation Award winning presentation, "Novel Acoustic Loading of a Mass Spectrometer - Towards Next Generation High Throughput MS Screening," presented by Jonathan Wingfield of AstraZeneca.
See all the on demand presentations from SLAS2015. Not a dues-paying member? Become one today and enjoy immediate access to these and all other paid-member benefits.
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Biomolecules Sorted with Catch-and-Release System
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A microtubule-inspired microfluidic system that resembles a microscopic forest of arms can pluck biomolecules out of liquid mixtures, carry them from one chemical stream to another, and then release them. The system, which is dynamic and tunable, may be suitable for applications in clinical diagnostics, target characterization, environmental analysis, and chemical purification.
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High-Resolution Chemical Depth Profiling of Solid Material Using a Miniature Laser Ablation/Ionization Mass Spectrometer
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High-resolution chemical depth profiling measurements of copper films are presented. The 10 μm thick copper test samples were electrodeposited on a Si-supported Cu seed under galvanostatic conditions in the presence of particular plating additives (SPS, Imep, PEI, and PAG) used in the semiconductor industry for the on-chip metallization of interconnects.
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Chemists Discover Temporary Phases of Chemical Structures
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The research group of Prof. Tomislav Friščić in McGill's Department of Chemistry has made a name for itself in the little-known, but growing field of "mechanochemistry," in which chemical transformations are produced by milling, grinding or shearing solid-state ingredients — brute force, in other words, rather than fancy liquid agents. "Your coffee maker grinds things," and grinding molecules in the lab involves much the same principle, Friščić notes.
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Budget Conflict Ramps Up
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Congress's consideration of the 2016 budget began with a bang when Republicans in the Senate and House of Representatives proposed 10-year plans that push broad spending cuts across the federal government. The moves are an attempt to eliminate the federal budget deficit.
The proposed budgets would slash broadly at discretionary spending — which includes almost all federal science funding — as well as suggest changes to big-ticket mandatory spending items such as Medicare.
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Editing Human Embryos is Genetics' New Battleground
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Replacing faulty genes in early human embryos and germ cells is within our grasp. Such changes affect DNA in the nucleus and so would be heritable; ultimately, they could be used to make a genetically modified baby.
There are already reports that groups in China, the U.S. and the biotech industry have done this kind of genetic engineering in the lab, prompting some scientists to call for a moratorium on this work.
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Real-Time Measurement of the Vertical Binding Energy during the Birth of a Solvated Electron
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Using femtosecond time-resolved two-photon photoelectron spectroscopy, we determine (i) the vertical binding energy (VBE = 0.8 eV) of electrons in the conduction band in supported amorphous solid water (ASW) layers, (ii) the time scale of ultrafast trapping at pre-existing sites (22 fs), and (iii) the initial VBE (1.4 eV) of solvated electrons before significant molecular reorganization sets in. Our results suggest that the excess electron dynamics prior to solvation are representative for bulk ASW.
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Team Finds Key to Making Neurons From Stem Cells
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A research team at UC San Francisco has discovered an RNA molecule called Pnky that can be manipulated to increase the production of neurons from neural stem cells.
The research, led by neurosurgeon Daniel A. Lim, M.D., Ph.D., and published on March 19 in Cell Stem Cell, has possible applications in regenerative medicine, including treatments of such disorders as Alzheimer's disease, Parkinson's disease and traumatic brain injury, and in cancer treatment.
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Uncovering a Reaction's Secrets
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A theoretical and experimental study could lead to improved catalysts for producing hydrogen fuel from waste biomass. Experimental analysis and computer simulations reveal new insights into the process by which ethanol produced from waste biomass can be converted into hydrogen in the presence of a catalyst. These insights should aid the design of more efficient catalysts for hydrogen production.
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Research Assistant
Brigham and Women's Hospital, Harvard Medical School, Harvard-MIT Health Sciences and Technology
US – MA – Boston
Laboratory Automation Engineer
New York Stem Cell Foundation
US – NY – New York
Assistant Professor Biomedical Sciences
Texas Tech University Health Sciences Center
US – TX – El Paso
More jobs at SLAS Career Connections
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