This message contains images. If you don't see images, click here to view.
Click here to advertise in this news brief.


  Mobile version   RSS   Subscribe   Unsubscribe   Archive   Media Kit Apr. 3, 2013    SLAS2014    Moving? New job? Let SLAS know.    






Providing clean, uninterrupted electrical power.

Certified UPS’s to protect your laboratory’s critical instrumentation and resolve current and potential power issues.


Gold Standard HTS Microplate Reader

Speed, sensitivity and precision in all detection modes. BMG LABTECH’s PHERAstar FS has no equal.

SLAS Offers Valuable Student Memberships

Benefit from scientific education, information resources, career-building opportunities and industry and peer networking.

Ultimate Online Product Directory

The SLAS Market Place offers access to new and existing technology products and services for your laboratory.




SLAS Electronic Laboratory Neighborhood e-zine: Managing Collaborative Science for Improved Patient Care
SLAS    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Spring 2013 SLAS Webinar Series presenters discuss working effectively in emerging markets, with contract research organizations and for transferring biological assays in the latest feature article in the SLAS Electronic Laboratory Neighborhood e-zine. Ajay Gautam of AstraZeneca, Jonathan Connick of Merck and Liming Shi of Eli Lilly help readers learn to formulate strategy, employ best practices and establish successful long-term collaborations. The three-part webinar series, "Effectively Managing Collaborative Science," upcoming live webinars will be held April 17 and May 15. The first webinar in the series from March is available on demand. More


SLAS2014 keynote speaker on The Colbert Report
SLAS    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Eric J. Topol, M.D., appeared on The Colbert Report to talk about his book, The Creative Destruction of Medicine: How the Digital Revolution Will Create Better Health Care. Topol succeeded in describing for the popular comedian's audience how new tools support a doctor's efforts. More

Sponsored Content


JBS Online features new manuscripts ahead-of-print
SLAS    Share    Share on FacebookTwitterShare on LinkedinE-mail article
"Development of a Novel β-Secretase Binding Assay Using the AlphaScreen Platform," "A Generic, Whole-Cell–Based Screening Method for Baeyer-Villiger Monooxygenases" and "Discovering New Medicines Targeting Helicases: Challenges and Recent Progress" are among the new manuscripts available only to SLAS Biomolecular Sciences Section members ahead-of-print. More

Multispan: Source for High Quality GPCR Assays

We offer the industry’s largest human and ortholog GPCR stable cell line collection and hundreds of customizable options for your functional and binding screening and profiling needs, with the highest quality and fastest turnaround. More>> Email:
Explore the latest innovations in motion and fluidics.
Parker Precision Fluidics offers laboratory solutions enabling precise motion and fluidics control for instrument accuracy. RoHS compliant products optimized for stability, long life, and efficiency. For more information visit or email

JALA scientific advisor named AACR inaugural fellow
SLAS    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Leroy E. Hood, M.D., Ph.D., president and co-founder of the Institute for Systems Biology, is among an elite group announced as the first class of fellows of the American Association for Cancer Research Academy. According to the March 25 news release, "The AACR Academy has been created to recognize and honor distinguished scientists whose major scientific contributions have propelled significant innovation and progress against cancer. These Fellows have been selected through a rigorous peer review process that evaluates individuals on the basis of their stellar scientific achievements in cancer research." Earlier this year, Hood received a National Medal of Science from President Barack Obama for his pioneering work in the systems approach to biology and medicine. More

2013 SLAS Asia Conference and Exhibition session spotlight: Drug Discovery Science; early-bird registration rates end April 9
SLAS    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Danyi Wen, M.D., M.B.A., Shanghai ChemPartner and Xiaoming Guan, Ph.D., GlaxoSmithKline (China) R&D, are the co-chairs for this session, which will address: "Novel Human Ig Transgenic Mouse Technology for the Development of Fully Human Therapeutic Antibodies," "Non-human Primates as an Animal Model in Drug Discovery," "The Road from Discovery to Clinic: A Story of Horizant" and "Innovative and Practical Approaches to New Drug Discovery at Hansoh Pharmaceutical." Register by Tuesday, April 9, and save! More

Gravimetric Sample Preparation from METTLER TOLEDO
Weigh the substance AND the solvent using Quantos automated dispensing systems from METTLER TOLEDO. Preparing accurate concentrations using gravimetric dosing complies with the latest USP guidelines <841>. It offers the benefits of improved quality of results; enhanced user safety; guaranteed process security; and minimized substance and solvent consumption. MORE
An Efficient Way To Increase Sample Throughput
Designed to enable labs to process samples simply and productively the INTEGRA VIAFLO 384 is a new handheld 384-channel electronic pipette that enables fast, precise and easy transfer of 384 samples simultaneously. Uniquely the VIAFLO 384 offers all the benefits of increased sample throughput as well as lower sample and reagent use without the expense of having to invest in a robotic liquid handling system. MORE
NEW SpectraMax® i3 Multi-Mode Microplate Platform
Imagine a multi-mode microplate reader that evolves over time. The system is equipped with spectral absorbance, fluorescence, and luminescence capabilities, while the patented flexible design allows the user to add application-specific cartridges such as HTRF, AlphaScreen, as well as first-in-market SpectraMax® MiniMax™ Imaging Cytometer option all in one compact platform. Learn more


Biomarkers for autism discovered
Science Daily    Share    Share on FacebookTwitterShare on LinkedinE-mail article
An important step towards developing a rapid, inexpensive diagnostic method for autism has been taken by Uppsala University, among other universities. Through advanced mass spectrometry the researchers managed to capture promising biomarkers from a tiny blood sample. The study has just been published in the journal Nature Translational Psychiatry. More

Medical science may be answer to budget woes
The Hill    Share    Share on FacebookTwitterShare on LinkedinE-mail article
"Sequestration" has forced the National Institutes of Health — the leading funder of biomedical research — to halt or cut funding to thousands of potentially groundbreaking research projects. On the 10th Anniversary of the completion of the Human Genome Project, we can't let the ongoing tug-of-war in Congress over spending priorities threaten the revolutionary work that is taking place in medical science," says JALA Scientific Advisor Leroy E. Hood, M.D., Ph.D., in The Hill's Congress Blog. More


Crystal-free crystallography
Chemical & Engineering News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Crystals are the preferred material chemists use to determine molecular structure via X-ray crystallography. But when scientists can't crystallize a substance, or not enough exists to get good crystals, they face a roadblock. Now, researchers have found a way to solve this problem using nanoscale scaffolds to capture the molecules they want to visualize. More

Researchers find surprising similarities between genetic and computer codes
Brookhaven National Laboratory    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The term "survival of the fittest" refers to natural selection in biological systems, but Darwin's theory may apply more broadly than that. New research from the U.S. Department of Energy's Brookhaven National Laboratory shows that this evolutionary theory also applies to technological systems. More

Best practices to optimize your cell-based assays
Genetic Engineering & Biotechnology News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Cell-based assays are routinely performed throughout the drug discovery process. However, there are issues that need to be overcome, including the edge effect, where cells in wells on the edge of an assay plate behave differently from those in the center. More

Crucial step in human DNA replication observed for first time
Science Daily    Share    Share on FacebookTwitterShare on LinkedinE-mail article
For the first time, an elusive step in the process of human DNA replication has been demystified by scientists at Penn State University. According to senior author Stephen J. Benkovic, an Evan Pugh Professor of Chemistry and Holder of the Eberly Family Chair in Chemistry at Penn State, the scientists "discovered how a key step in human DNA replication is performed." More

Short Guide to 3-D Cell Culture
AMSBIO     Share    Share on FacebookTwitterShare on LinkedinE-mail article
AMSBIO has released a guide to assist research scientists looking to culture cells in more physiologically relevant environments. Traditional monolayer cell culture on plastic dishes or in flasks rarely recreates the conditions cells experience in vivo. This guide provides background information describing a 3-D cell culture and why researchers are increasingly switching to it. Many types of 3-D cell culture matrices for spheroid, organotypic and directional cultures are described in addition to natural hydrogels, scaffold-free cell culturing, artificial scaffolds and synthetic biomimetics. More

Starfruit SNP Comparison Software Service

Starfruit Software/Database Service
– You can analyze DNA samples for specific SNP patterns susceptible to a disease or disorder. Visit Store to see "Starfruit GeneTell LIMS"
Interested in outsourcing bioassays and screening?

We are a pre-clinical CRO specialising in bespoke bioassay development, plate-based compound pharmacology and instrument/reagent validation. Contact us at

Selective inhibition of extracellular thioredoxin by asymmetric disulfides
Journal of Medicinal Chemistry    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Whereas the role of mammalian thioredoxin as an intracellular protein cofactor is widely appreciated, its function in the extracellular environment is not well-understood. Only few extracellular targets of Trx-mediated thiol–disulfide exchange are known. For example, Trx activates extracellular transglutaminase 2 via reduction of an intramolecular disulfide bond. More

SCOTUS weighs pay-for-delay
eBio News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The U.S. Supreme Court recently heard arguments in a case that could put an end to so-called pay-for-delay settlements between branded pharmaceutical makers and their generic competitors. Critics of these agreements argue that they are anticompetitive, costing consumers billions of dollars by delaying competition from entering the market. More


Italy pushes on with controversial stem cell therapy
NewScientist    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Italian health officials are allowing a handful of patients to continue with a controversial stem cell therapy amid protests from scientists that the treatments are unproven and unsafe. The Stamina Foundation has been administering the therapy at a public hospital to people with a range of degenerative diseases. Their approach is based on mesenchymal stem cells, derived from bone marrow, which can become mature bone and connective tissue. More

Reaction pathways for Maillard degradation of vitamin C    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Vitamin C is found in many foods, and, among other things, is used to prolong shelf life. However, it is not stable in air or at room temperature. Cut fruits turn brown and the tastes of foods change. In the journal Angewandte Chemie, German researchers have now presented a systematic study of the processes that occur during the degradation of vitamin C. More

X-ray free electron lasers motivate bioanalytical characterization of protein nanocrystals: Serial femtosecond crystallography
Analytical Chemistry    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Atomic resolution structures of large biomacromolecular complexes can now be recorded at room temperature from crystals with submicrometer dimensions using intense femtosecond pulses delivered by the world's largest and most powerful X-ray machine, a laser called the Linac Coherent Light Source. More

New Biohit Picus Electronic Pipette

Sartorius Biohit presents the Picus, the smallest and lightest electronic pipette that eases your workload and provides accurate and precise results. This unique pipette design features patented electronic tip ejection and an intuitive user interface. The Picus has been presented with the 2012 “Red Dot” design award.

Discover Picus at
Add-and-Read Plate Reader
Get results fast with Hamamatsu’s FDSS µCELL, an imaging-based microplate reader. This affordable, simple-to-use reader accommodates 96- or 384-well microplates for kinetic cell-based assays such as GPCR, ion channel, prolyl isomerase, transporter, and light-activated receptor or channel assays. Click here for more info.
30 Seconds Can Save You 90% on Pipette Tips
IONFIELD SYSTEMS TipCharger™ system uses high-efficiency plasma technology to renew pipette tips. Organic contaminants such as DNA, RNA and compounds are ionized in seconds, allowing disposable tips to be used over and over again! Watch TipCharger Animation Video and see how 30 seconds can save your lab $250,000 per year.


Science Director, Clinical Biomarkers
CHDI Foundation/CHDI Management
USA – NJ – Princeton

QC Senior Scientist – Commercial
USA – CA – South San Francisco

Technical Sales Specialist
United Kingdom – Cambridge

More jobs at SLAS Career Connections


SLAS Point-to-Point
Colby Horton, Vice President of Publishing, 469.420.2601
Download media kit

Dennis Hall, Senior Content Editor, 469.420.2656   
Contribute news

This edition of SLAS Point-to-Point was sent to ##Email##. To unsubscribe from receiving SLAS Point-to-Point, click here. To unsubscribe from all SLAS e-mail communications, please click here. Did someone forward this edition to you? Subscribe here — it's free!

SLAS Terms of Use Policy
Recent issues

April 3, 2013
March 27, 2013
March 20, 2013
March 13, 2013

7701 Las Colinas Ridge, Ste. 800, Irving, TX 75063