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  Mobile version   RSS   Subscribe   Unsubscribe   Archive   Media Kit Apr. 10, 2013

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news


SLAS Webinar on April 17: Lessons Learned in Pharma - CRO Collaboration in Discovery Research
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"Collaborations in general, and working with CROs specifically, have grown from a piece-meal, transactional way of doing business to a more strategic method. The way we do partnerships today is with long-term plans and partners. Engaging much more actively with CROs, we work together to solve problems," says Jonathan H. Connick, Ph.D., of Merck in Shanghai, China, who will lead this second in the Spring 2013 SLAS Webinar Series on Effectively Managing Collaborative Science. SLAS Webinars are free to paid SLAS members, and registration is now open. More

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Chad Mirkin's exciting work with spherical nucleic acids
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Now in the SLAS Electronic Laboratory Neighborhood e-zine — an exploration of this Northwestern University professor's latest discovery that enables researchers to take measurements within live cells. Mirkin, also director of the International Institute for Nanotechnology, JALA Scientific Advisor and 2013 SLAS Asia Conference and Exhibition keynote speaker, says "We're now investigating the use of SNAs as gene-regulation agents for therapeutic purposes, looking at ways to track disease at much earlier stages so we can treat it at much earlier stages, and at the same time, enable more rapid discovery of potential therapeutic agents." More

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JALA Online features new manuscripts ahead-of-print
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"Automated UV-C Mutagenesis of Kluyveromyces marxianus NRRL Y-1109 and Selection for Microaerophilic Growth and Ethanol Production at Elevated Temperature on Biomass Sugars" and "Improvement of the Positional Dispensing in the Washing Machine MW 2001" are among the new manuscripts available only to SLAS Laboratory Automation Section members ahead-of-print. More

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2013 SLAS Asia Conference and Exhibition session spotlight: SLAS2013 Innovation Award Finalists
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The 2013 SLAS Innovation Award winner and two Innovation Award finalists, recognized for extraordinary achievement in innovative laboratory science and technology, will share their celebrated SLAS2013 presentations in Shanghai: "Making a Quantum Leap in Mass Spectrometry Throughput: Applying the NextVal MassInsight Technology to Monitor Cytochrome P450 Enzyme Inhibition in Human Liver Microsomes" by Andrea Weston, Bristol-Myers Squibb; "Genomic Applications of Droplet Microfluidics" by Darren Link, RainDance Technologies; and "A Multiplexed Fluorescent Assay for Independent Second Messenger Systems: Decoding GPCR Activation in Living Cells" by Paul Tewson, Montana Molecular. This session is chaired by Ying Yang, M.B.A., LBD Life Sciences China and Yingguang Wu, Ph.D., Tecan (Shanghai) Trading. More

May 1 deadline approaches for JBS special issue on Knowledge from Small-Molecule Screening & Profiling Data
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Guest Editors Paul A. Clemons, Ph.D., and Darren Green, Ph.D., are accepting manuscript proposals through May 1 for the next special issue of the Journal of Biomolecular Screening. The editors are especially interested in proposals related to the production, integration, analysis and mining of large datasets relevant to biological discovery, including chemical genomics, network biology and phenotypic drug discovery. More


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New LabAutopedia Video of the Month: 3-D Printing
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News reports abound on interesting applications of 3-D printing, with innovative applications being developed frequently. How might 3-D printing be used in the laboratory? Please take the brief poll below, and send any further comments to lvalastyan@slas.org. More

Are you using 3-D printing in your laboratory?
  • Yes
  • Equipment on order (or soon will be)
  • Actively investigating possible use
  • May consider
  • No
Click here to give SLAS your answer.


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Researchers and advocates gather in Washington to protest cuts to biomedical research
ScienceInsider    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Thousands of scientists and patient advocates poured into a square in downtown Washington on Monday to hold what organizers billed as the largest-ever rally to call for more funding for biomedical research. The event, held in conjunction with the annual meeting of the American Association for Cancer Research with support from over 200 organizations, aimed to draw attention to the 5 percent cut to the National Institutes of Health's $31 billion budget imposed by Congress last month. More

Ring cycle for dilating and constricting the nuclear pore
Proceedings of the National Academy of Sciences    Share    Share on FacebookTwitterShare on LinkedinE-mail article
We recently showed that the three "channel" nucleoporins, Nup54, Nup58, and Nup62, interact with each other through only four distinct sites and established the crystal structures of the two resulting "interactomes," Nup54•Nup58 and Nup54•Nup62. We also reported instability of the Nup54•Nup58 interactome and previously determined the atomic structure of the relevant Nup58 segment by itself, demonstrating that it forms a twofold symmetric tetramer. More

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Scientific articles accepted (personal checks, too)
The New York Times    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The scientists who were recruited to appear at a conference called Entomology-2013 thought they had been selected to make a presentation to the leading professional association of scientists who study insects. But they found out the hard way that they were wrong. The prestigious, academically sanctioned conference they had in mind has a slightly different name: Entomology 2013 (without the hyphen). The one they had signed up for featured speakers who were recruited by e-mail, not vetted by leading academics. More

The search for new antibiotics: Tiny proteins prevent bacterial gene transcription
Phys.org    Share    Share on FacebookTwitterShare on LinkedinE-mail article
In the search for new antibiotics, researchers are taking an unusual approach: They are developing peptides, short chains of protein building blocks that effectively inhibit a key enzyme of bacterial metabolism. Now, scientists at the Helmholtz Institute for Pharmaceutical Research Saarland in Saarbrücken, a branch of the Helmholtz Center for Infection Research, have published their findings and the implications for potential medical application in the scientific journal ACS Chemical Biology. More


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How Thatcher the chemist helped make Thatcher the politician
Popular Science    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Margaret Thatcher died Monday at 87. She'll be remembered as the first (and only) woman to be prime minister of Britain, but what's often missed or only glanced over in her biographies, and now her obituaries, is her career as a chemist. Thatcher graduated from Oxford in 1947 with an undergraduate degree in chemistry. Her fourth-year dissertation was on X-ray crystallography of the antibiotic cocktail gramicidin, and her supervisor, Dorothy Hodgkin, was working at the time on the structure of penicillin. More

Stem cells enable personalized treatment for bleeding disorder
eBioNews    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Scientists have shed light on a common bleeding disorder by growing and analyzing stem cells from patients' blood to discover the cause of the disease in individual patients. The technique may enable doctors to prescribe more effective treatments according to the defects identified in patients' cells. In the future, this approach could go much further: these same cells could be grown, manipulated and applied as treatments. More

Solid-state NMR on bacterial cells: Selective cell wall signal enhancement and resolution improvement using dynamic nuclear polarization
Journal of the American Chemical Society    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Dynamic nuclear polarization enhanced solid-state nuclear magnetic resonance has recently emerged as a powerful technique for the study of material surfaces. In this study, we demonstrate its potential to investigate cell surface in intact cells. Using Bacillus subtilis bacterial cells as an example, it is shown that the polarizing agent 1-(TEMPO-4-oxy)-3-(TEMPO-4-amino)propan-2-ol (TOTAPOL) has a strong binding affinity to cell wall polymers. More



Tin nanocrystals for the battery of the future
ScienceDaily    Share    Share on FacebookTwitterShare on LinkedinE-mail article
More powerful batteries could help electric cars achieve a considerably larger range and thus a breakthrough on the market. A new nanomaterial for lithium ion batteries developed in the labs of chemists at ETH Zurich and Empa could come into play here. They provide power for electric cars, electric bicycles, smartphones and laptops; nowadays, rechargeable lithium ion batteries are the storage media of choice when it comes to supplying a large amount of energy in a small space and light weight. More

BREAD Ideas Challenge
National Science Foundation    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The BREAD Ideas Challenge is an opportunity for researchers in the agricultural sciences to bring attention to what they believe are the most pressing issues facing smallholder farmers in the developing world today. Not only will the prizewinning Challenge Ideas be showcased for the international community to draw attention to these important challenges: Prizewinners will also receive up to $10,000 each for the best ideas! More

Webinar: Methods to Improve Chemical Process Development
METTLER TOLEDO    Share    Share on FacebookTwitterShare on LinkedinE-mail article
METTLER TOLEDO's Adrian Burke discusses the changing nature of today's business that forces companies to complete more projects faster than ever before, with ever-decreasing resources. Four specific challenges in chemical process development covered include reducing the cost of materials, reducing development time, ensuring successful process scalability and speeding high-quality process optimization. More


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Career


Senior Research Investigator (PhD Chemical Engineer)
Bristol-Myers Squibb
USA – NJ – New Brunswick

Postdoctoral Position: Image-based Profiling
Broad Institute of Harvard and MIT
USA – MA – Cambridge

Research Scientist, in vitro Biology
Orion Corporation
Finland – Turku

More jobs at SLAS Career Connections


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