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Students, graduate students, post-doctoral associates and junior faculty may apply for travel awards. 56 awarded for SLAS2015.
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SLAS ELN Reports: Robyn Rourick — Consider Career Change through Others' Eyes
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The Genentech scientific manager and former member of the SLAS Board of Directors talks about science, career opportunities, volunteerism, art, family, networking and how all these pieces work together as one goes through life. She endorses authentic networking to build long-lasting relationships.
"Some people network to make their next move or to get that connection that they feel that they need," she explains. "There's not necessarily depth to it. I think to network authentically, you need to build deeper relationships. It allows you to build connectivity, so people understand you. There's sustainable value in that."
Read more in the SLAS Electronic Laboratory Neighborhood e-zine.
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SLAS's Eric Pei-Yu Chiou: Researchers Deliver Large Particles Into Cells at High Speed
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A new device developed by UCLA engineers and doctors may eventually help scientists study the development of disease, enable them to capture improved images of the inside of cells and lead to other improvements in medical and biological research.
The researchers created a highly efficient automated tool that delivers nanoparticles, enzymes, antibodies, bacteria and other "large-sized" cargo into mammalian cells at the rate of 100,000 cells per minute — significantly faster than current technology. Read more about Chiou in the SLAS Electronic Laboratory Neighborhood e-zine.
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JALA and JBS Author Workshops in Asia
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SLAS President Dean Ho presented What Editors Want: A Guide to Publishing in Scientific Journals at Shanghai Jiao Tong University on April 8.
Ho offered step-by-step advice on how to design and write scientific research papers more clearly and effectively to improve their chances for successful publication.
Two similar workshops are planned in Singapore — May 22 at Nanyang Technological University and May 25 at National University of Singapore.
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Open Access at JBS Online: A Quantitative Microtiter Assay for Sialylated Glycoform Analyses Using Lectin Complexes
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Fidelity of glycan structures is a key requirement for biotherapeutics, with carbohydrates playing an important role for therapeutic efficacy.
Comprehensive glycan profiling techniques such as liquid chromatography and mass spectrometry, while providing detailed description of glycan structures, require glycan cleavage, labeling, and paradigms to deconvolute the considerable data sets they generate.
The JBS authors from Momenta Pharmaceuticals describe their work, which involves using lectins as probes on microarrays.
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Why limit recovery or capacity to clarify cellular debris from your sample? For a variety of integrated pre-filter options tailored to your research needs, visit Pall Laboratory website.
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2015 SLAS Asia Conference and Exhibition Draws Nearly 450 to Shanghai
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Come Transform Research, held April 9-10, was organized around four scientific sessions — Leading Science for Small Molecules Drug Discovery; Natural Product Drug Discovery & Synthetic Biology; The Scientific Frontier of Biological Discovery; and From Technology, Process, Discovery to Development.
The event also included exhibits, posters, exhibitor tutorials, networking and, along with WuXi AppTec, a pre-conference workshop on Developing an Open Platform for Compound Management and In Vitro Screening.
Pictured here is K. Barry Sharpless, 2001 Nobel Prize in Chemistry winner, presenting Going Fishing for Better Medicines.
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Crazy Smart: When A Rocker Designs A Mars Lander
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National Public Radio (NPR) captures the intensity of the undertaking when Adam Dietrich Steltzner and his team at the Jet Propulsion Laboratory (JPL) invented the pioneering landing system that placed the Curiosity rover on Mars.
The interview reaches back to uncover Steltzner's original career path in rock and roll and the experience he had on the way home from a gig that led to his eventual groundbreaking work at NASA's JPL.
The NPR website also includes a link to the popular video — Seven Minutes of Terror: The Challenges of Getting to Mars, and sketches of engineering designs that didn't make it to the final product. Steltzner is a keynote speaker at SLAS2016, Jan. 23-27, 2016, San Diego, CA.
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SLAS2015 Keynote Presentation Featured at Elsevier Connect
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The article published April 6 — Could organs-on-chips replace drug testing on animals? — summarizes the SLAS2015 presentation by Donald Ingber, founding director of the Wyss Institute for Biologically Inspired Engineering at Harvard University.
At SLAS2015, Ingber described why he feels organs-on-chips — microdevices that contain human cells and designed to function as human organs — are the way to move drug discovery and development forward.
"To go from bio-inspiration to innovation requires quite a bit of perspiration," as well as collaboration "from every possible discipline," Dr. Ingber concluded. "You really need to break down those boundaries to do something like this."
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Gut Microbes Aid Neurotransmitter Production
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Upon seeing the word neurotransmitter, most of us would conjure up some brain centric image or think about its deficiency in some psychological condition. However, it has been estimated that 90 percent of the serotonin produced within the human body is derived from the digestive tract. Furthermore, aberrant levels of peripheral serotonin have been linked to diseases such as osteoporosis and irritable bowel syndrome. Now, new research from scientists at the California Institute of Technology shows the importance of gut bacteria in the production of peripheral serotonin.
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Engineers Now Understand How Complex Carbon Nanostructures Form
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Carbon nanotubes (CNT) are microscopic tubular structures that engineers "grow" through a process conducted in a high-temperature furnace. The forces that create the CNT structures known as "forests" often are unpredictable and are mostly left to chance. Now, a researcher has developed a way to predict how these complicated structures are formed. By understanding how CNT arrays are created, engineers can better incorporate the highly adaptable material into devices and products.
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A New Candidate for CRISPR
Drug Discovery News Share
The promise of genome editing — being able to adjust the activity of different genes precisely and efficiently — could have a variety of applications in health management, but as with all emerging technologies, there are hurdles to overcome. Fortunately, a multi-institute group of scientists may have solved one of the primary issues impeding the advancement of this approach.
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Scientists a Step Closer to Developing Renewable Propane
Lab Manager Share
This study provides new insight and understanding of the development of next-generation biofuels. In this latest study, published in the journal Biotechnology for Biofuels, scientists at the University's Manchester Institute of Biotechnology, working with colleagues at Imperial College London and University of Turku, have created a synthetic pathway for biosynthesis of the gas propane.
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Study Raises Questions About Measuring Radioactivity in Fracking Wastewater
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Commonly used testing methods may underestimate the total radioactivity of wastewater produced by gas wells that use hydraulic fracturing, or fracking, to tap the Marcellus Shale, a geological formation in the northeastern United States, concludes a new study. The findings suggest government agencies should consider retooling some testing recommendations and take a fresh look at possible worker exposure to potentially harmful waste, the authors say.
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Fluorescence Studies Reveal How Cells Take Out Their Protein Garbage
Chemical & Engineering News Share
The breakdown of old, unneeded, and defective proteins in the proteasome, the cellular trash can for proteins, is as essential to cells as garbage pickups are to neighborhoods. A research team now provides a more complete picture of the way cells use peptides to mark proteins for disintegration in the proteasome. In one type of protein degradation, peptides called ubiquitins are added to proteins to tag them for disposal.
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Researchers Create a 'Living Kidney Membrane'
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Researchers at the MIRA research institute of the University of Twente and the Radboudumc have created a "living membrane" combining kidney epithelial cells with a polymeric artificial membrane. This achievement is a first but significant step towards development a new treatment for kidney patients. This research, which started within the BMM - BioKid project (2009-2014), is currently continued within the EU Marie Curie ITN project "Bioart."
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Research Technician IV
Children’s Hospital of Philadelphia
US – PA – Philadelphia
Regulatory Affairs Specialist
STEMCELL Technologies
Canada – BC – Vancouver
Chair Professor, Junior Faculty Positions
Frontier Institute of Science and Technology (FIST), Xi’an Jiaotong University (XJTU)
China – Shaanxi Province, Xi’an
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