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  Mobile version   RSS   Subscribe   Unsubscribe   Archive   Media Kit Apr. 18, 2012

SLAS.org    SLAS2013    Moving? New job? Let SLAS know.      


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SLAS2013 call for abstracts now open!
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Interested in sharing your work with the laboratory science and technology community at SLAS2013, Jan. 12-16, Orlando, Fla.? Submit your abstract for a podium presentation by July 30 and/or a poster presentation by Oct. 26. SLAS2013 educational tracks are Assay Development and Screening; High-Throughput Technologies; Micro/Nano Technologies; Informatics; Diagnostics; Bioanalytical Techniques; and Drug Target Biology. More

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2012 SLAS Asia Conference discounts end Monday
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Register by Monday, April 23, and save! The 2012 SLAS Asia Conference and Exhibition, "Advances in Drug and Life Sciences R&D Through Laboratory Technology," June 19-21, Shanghai, explores drug discovery technologies, stem cells in drug discovery, and drug discovery from screening to therapy. More



Small automated pipettors perform big
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LabAutopedia seeks editor
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An energetic SLAS volunteer is needed to build and manage content for the SLAS LabAutopedia wiki. This free, web-based information and idea exchange for laboratory science and technology has enjoyed more than 2.3 million page views to date. This is a unique opportunity to contribute to the success and momentum of an important SLAS initiative. A small stipend is offered. More


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"Negotiating Work and Life — How to Find the Joy"
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There are no easy answers to negotiating a demanding career in science with other interests and priorities, but many find it helpful to obtain support and ideas from those who seem to be managing. Joanne Kamens of Addgene shares her thoughts in a new feature on SLAS Electronic Laboratory Neighborhood. More

Rao editorial: The NIH and the regenerative medicine field
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"Stem cells come in many flavors. The scientific distinction to make between these cells is not whether they are embryonic, fetal, adult or cadaveric, but rather the properties of the particular stem cell that is harvested for use." 2012 SLAS Asia Conference and Exhibition keynote speaker Mahendra Rao comments in the March 2012 issue of Regenerative Medicine. More

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JALA Online releases new manuscripts
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"Detection of Cells Captured with Antigens on Shear Horizontal Surface-Acoustic-Wave Sensors" and "Performance Evaluation of 3D Polystyrene 96-Well Plates with Human Neural Stem Cells in a Calcium Assay" are among the articles published online ahead of print. More

SLAS ELN awards $500 Amazon gift card
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Kevin McLeaster, Laboratory Automation Engineer, Discovery Chemistry Research, Eli Lilly and Company, Indianapolis, Ind., is the winner of the SLAS ELN Welcome to the Neighborhood sweepstakes. Congratulations Kevin! Keep reading and enjoying the SLAS e-zine — people focused and people sourced. More


New Biohit Roboline™ Liquid-Handling Automate
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Investigate major signaling pathways
Cisbio provides a panel of cellular kinase assays dedicated to the measurement of site-specific phosphorylation, in an endogenous cellular environment. These homogeneous assays represent a reliable, robust and rapid alternative to classical technologies like Western Blot, ELISA or bead-based assays.
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Science crowdfunding website PetriDish.org approaches first $100,000 raised
TPM Idea Lab    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Petridish.org, a crowd-funding website restricted specifically to accredited scientific research projects, is getting close to its first $100,000 in funds raised just a month after launching, according to founder Matt Salzberg. "We have had two projects successfully reach the end of their funding cycles and both earned about $10,000 each," Salzberg told TPM in a telephone interview. More



Controlling the code
Chemical & Engineering News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
DNA carries the instructions for assembling all of life's essential building blocks. Logic would have it that decoding the human genome, achieved a decade ago, would set out a straight, if dauntingly steep, path for inventing new drugs: Determine the genetic mutation driving a disease and then find the right compound to overcome it. More

How tropolones synthesized in fungi: 70-year-old chemical mystery solved
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Chemists and biologists from the University of Bristol have finally cracked one of the longest standing chemical mysteries. In a paper published in the Proceedings of the National Academy of Sciences, the team demonstrated exactly how an unusual class of compounds known as tropolones are synthesized in fungi. More


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Branchpoint expansion in a fully complementary 3-way DNA junction
Journal of the American Chemical Society    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Branched nucleic acid molecules serve as key intermediates in DNA replication, recombination and repair; architectural elements in RNA; and building blocks and functional components for nanoscience applications. Using a combination of high-resolution single-molecule FRET, time-resolved spectroscopy and molecular modeling, we have probed the local and global structure of a DNA three-way junction in solution. More

Dried blood spot analysis by digital microfluidics coupled to nanoelectrospray ionization mass spectrometry
Analytical Chemistry    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Dried blood spot samples on filter paper are surging in popularity as a sampling and storage vehicle for a wide range of clinical and pharmaceutical applications. For example, a DBS sample is collected from every baby born in the province of Ontario, Canada, for quantification of approximately one hundred analytes that are used to screen for 28 conditions, including succinylacetone, a marker for hepatorenal tyrosinemia. More

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Human eggs grown in lab could produce unlimited supply of humans
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The first human eggs grown from human stem cells could be fertilized with human sperm cells later this year, potentially revolutionizing fertility treatment for women. This could be one more step on the path toward reproduction sans human interaction — in this case, a potential parent wouldn't even need to donate her eggs. More

Water, water everywhere — but is it essential to life?
Science Daily    Share    Share on FacebookTwitterShare on LinkedinE-mail article
New research by scientists at the University of Bristol has challenged one of the key beliefs in chemistry: that proteins are dependent on water to survive and function. The team's findings, published this month in Chemical Science, could eventually lead to the development of new industrial enzymes. More

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Best evidence yet that a single gene can affect IQ
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A massive genetics study relying on fMRI brain scans and DNA samples from over 20,000 people has revealed what is claimed as the biggest effect yet of a single gene on intelligence — although the effect is small. There is little dispute that genetics accounts for a large amount of the variation in people's intelligence, but studies have consistently failed to find any single genes that have a substantial impact. More

Secrets of molecule that helped build the universe exposed
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A new study of one of the most fundamental molecules in the universe has given scientists clues into how the very first stars were formed. For the first time, researchers have calculated the vibration patterns of a compound called H3+ (also known as a triatomic hydrogen ion), which consists of three hydrogen atoms sharing two electrons. More

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1,3,8-triazaspiro[4.5]decane-2,4-diones as efficacious pan-inhibitors of hypoxia-inducible factor prolyl hydroxylase 1-3 (HIF PHD1-3) for treatment of anemia
Journal of Medicinal Chemistry    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The discovery of 1,3,8-triazaspiro[4.5]decane-2,4-diones (spirohydantoins) as a structural class of pan-inhibitors of the prolyl hydroxylase (PHD) family of enzymes for the treatment of anemia is described. The initial hit class, spirooxindoles, was identified through affinity selection mass spectrometry (AS-MS) and optimized for PHD2 inhibition and optimal PK/PD profile (short-acting PHDi inhibitors). More

Outsourcing trends in China
Genetic Engineering & Biotechnology News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Compared with its counterparts in other countries, the Chinese pharma services industry has been developing extraordinarily fast in the past decade. Although only having a short service history, it has attracted a large number of pharma and biopharma companies almost from all over the world for a variety of outsourcing opportunities. More


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Rapid Sample Transfer Between Different Labware Formats
This application note by INTEGRA discusses and demonstrates how the advent of adjustable spacing multichannel pipettes presents labs with a valuable new tool for accelerating tasks where samples need reformatting while at the same time increasing precision, reliability and comfort of the pipetting procedure. MORE
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Announcing Labcyte Consumables Website
Labcyte has introduced a new consumables website designed to be a one stop solution for Labcyte® consumables, from product research to purchase and fulfillment. The new website will allow you to:

• Review product specifications
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Visit microplates.labcyte.com for the latest product information.


Career


Institute Associate Scientist II
MD Anderson Cancer Center
USA – TX – Houston

Assistant Professor – Biological Systems Engineering
University of Wisconsin-Madison
USA – WI – Madison

Director of Clinical Operations
Onyx Pharmaceuticals
USA – CA – South San Francisco

More jobs at SLAS Career Connections


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Get your free automation consultation
Astech Projects launch new turnkey approach to automation at SLAS! Composed of four key steps – consultation & proposal, concept design study, proof of concept, and detailed design, manufacture and testing – Astech currently offers the initial consultation & proposal free of charge. Apply for yours today.


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