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SLAS is Now Accepting Abstracts for SLAS2017!
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The SLAS2017 Scientific Program Committee is now accepting abstract submissions for the next SLAS International Conference and Exhibition, Feb. 4-8, 2017, Washington, DC. Abstracts are being sought for podium and poster presentations in seven educational tracks:
- Assay Development and Screening
- Automation and High-Throughput Technologies
- Micro- and Nanotechnologies
- Advances in Bioanalytics, Biomarkers and Diagnostics
- Cellular Technologies
- Data Analysis and Informatics
- Drug Target Strategies
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SLAS CEO Greg Dummer to Resign
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SLAS Chief Executive Officer Gregory Dummer, CAE, has announced his resignation from the Society effective June 30. He is departing SLAS to become CEO of the American Orthopaedic Society for Sports Medicine. The SLAS Executive Search Committee is accepting CVs from potential CEO candidates through the end of May.
"Greg's vision and leadership guided the creation and growth of SLAS into its position as the world's leading nonprofit membership society devoted exclusively to serving the life sciences discovery and technology community," says SLAS President Richard Eglen, Ph.D. (Corning Life Sciences, USA). "He has made significant contributions to the Society’s success, including overseeing the unification of the two international Societies that resulted in the formation of SLAS; working closely with volunteer leaders to build a robust menu of educational products, programs, services and events; as well as attracting and inspiring a world class professional team. We wish him the very best in his new role."
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SLAS ELN Reports: Technology Advancements Improve Both Clinical and Research-Based Imaging Needs
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The April JALA Special Issue on High-Throughput Imaging Technologies features peer‐reviewed original research reports from Finland, France, Italy, Hungary, Spain, and the United States focusing on advancements that integrate automation and high-throughput into traditional and emerging imaging applications.
"The original research, technology briefs and informative review presented in this JALA special issue on high-throughput imaging cover a wide range of both basic life sciences research as well as clinical applications where advances in imaging technology surrounding these applications will greatly impact and improve how imaging is utilized to both better understand the intricacies of life as well as diagnose and treat patients in a more cost-efficient and less-invasive manner," says JALA Editor-in-Chief Edward Kai-Hua Chow, National University of Singapore.
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NEW in April at JBS Online
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"A Quantitative Spectrophotometric Assay to Monitor the tRNA-Dependent Pathway for Lipid Aminoacylation In Vitro," "Development of an Enhanced Phenotypic Screen of Cytotoxic T-Lymphocyte Lytic Granule Exocytosis Suitable for Use with Synthetic Compound and Natural Product Collections," "Identification of Small-Molecule Frequent Hitters of Glutathione S-Transferase–Glutathione Interaction" and "A Multiplexed High-Content Screening Approach Using the Chromobody Technology to Identify Cell Cycle Modulators in Living Cells" are peer-reviewed research articles added this month.
JBS reports how scientists develop and utilize novel technologies and/or approaches to provide and characterize chemical and biological tools to understand and treat human disease. These new manuscripts are available to SLAS Biomolecular Sciences Section members and JBS subscribers ahead-of-print.
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SLAS Europe Compound Management in Industry and Academia Conference Draws 110 Participants
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The focused event in Berlin last week featured strong podium and poster presentations with excellent participant interaction. In addition, 14 exhibitors were on hand. To keep the discussion going year-round, participants created a new SLAS LinkedIn group — European Compound Management SIG (Special Interest Group).
Kirsty Davidson, University of Dundee (Scotland, U.K.), won the student poster competition with her research, "Assembly of the DDU and GHCDL Lead-Like Diversity Libraries." Davidson's co-authors were Alex Cookson, Michael Kiczun, James Roberts, Emma Gutcher and David Gray. View photos.
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Sign Up for FREE E-Mail Alerts from JALA and JBS
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 Be the first to know when new scientific reports publish ahead-of-print and when new issues of JALA and JBS become available by signing up for free e-mail alerts at JALA Online and JBS Online.
Sign up for keyword alerts to be the first to know when new material about a particular topic becomes available. Plus, authors whose work has been published in JALA and JBS can sign up for citation tracking alerts. All for FREE!
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Computer Algorithm Helps Characterize Cancerous Genomic Variations
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Scientists at the University of California San Diego School of Medicine and the Broad Institute say they have developed a new computer algorithm — REVEALER — to better characterize the functional context of genomic variations in cancer. The tool is designed to help researchers identify groups of genetic variations that together associate with a particular way cancer cells get activated, or how they respond to certain treatments.
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New Optogenetic Tool Moves Proteins Within Cells to Study Biological Changes
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Scientists at the University of North Carolina School of Medicine have developed a way to embed light-responsive switches into proteins so that researchers can use lasers to manipulate protein movement and activity within living cells and animals.
Using this technique, the UNC team of scientists forced proteins out of the cell nucleus and into the cytoplasm, where they could no longer do their jobs.
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First Radical Route to Chiral Quaternary Carbons Reported
Chemical & Engineering News Share
Many natural products, pharmaceuticals, and other biologically active molecules feature chiral carbon atoms attached to four other carbons. Chemists can synthesize these quaternary stereocenters using organometallic reagents that add carbon groups to conjugated carbonyl compounds. These reagents, however, are expensive and hard to generate, can cause problematic side reactions, and don't always work well at crowded carbon centers.
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Napster Co-founder Bankrolls Project to Speed Cancer Work
Bioscience Technology Share
A project to speed development of cancer-fighting drugs that harness the immune system has academic and drug industry researchers collaborating and sharing their findings like never before.
The newly created Parker Institute for Cancer Immunotherapy is being funded by a $250 million grant from Sean Parker, the co-founder of the file-sharing site Napster and Facebook's first president.
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Electrooxidation of New Synthetic Cannabinoids: Voltammetric Determination of Drugs in Seized Street Samples and Artificial Saliva
Analytical Chemistry Share
The electrochemical sensing of new psychoactive substances, synthetic cannabinoids (SCs), commonly marketed under the trade name "Spice" is explored for the first time. The electrooxidative transformations of 11 new indole and indazole SCs which are currently the predominant illicit smoking mixtures on the drug market is performed using cyclic and differential pulse voltammetry with various commercially available electrodes (Pt, GC, Bdd).
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Study: Fossil Fuels Could Be Phased out Worldwide in a Decade
Lab Manager Share
The worldwide reliance on burning fossil fuels to create energy could be phased out in a decade, according to an article published by a major energy think tank in the U.K.
Professor Benjamin Sovacool, Director of the Sussex Energy Group at the University of Sussex, believes that the next great energy revolution could take place in a fraction of the time of major changes in the past.
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Tracking Zika's Evolution
The Scientist Share
Comparing the sequences of 30 strains of Zika virus isolated from humans, 10 from mosquitoes, and one from monkeys has revealed significant evolutionary change over the past 70 years, according to a study published in Cell Host & Microbe. Specifically, the sequences of the viral strains showed notable divergence between the Asian and African lineages and suggest that modern Zika virus strains derived from the Asian lineage.
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Using Methane Rather Than Flaring It
Science Daily Share
Methane is an abundant and inexpensive gas. Although it would be a suitable energy source and base material for the chemical industry, huge quantities of it are simply burnt off around the world — above all at oil fields and refineries. "On satellite images of Earth at night, the Middle East is brightly illuminated. This is not because the region has an especially high number of large, brightly lit settlements, but rather because of methane flaring at the oil fields," says Jeroen van Bokhoven, Professor for Heterogeneous Catalysis at ETH Zurich.
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Postdoctoral Position in Bionanotechnology
University of Washington
US – WA – Seattle
Phase 1 Experimental Therapeutics Program Director
Children's Mercy Hospital
US – MO – Kansas City
Scientist III
BASF
US – NC – Research Triangle Park
Search Jobs at SLAS Career Connections
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