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Log in to SLAS APPLIED and catch up on current topics of interest through conference and symposia recordings, webinars and podcasts. Recently released modules include the SLAS2020 Conference Recordings; SLAS Technology, SLAS Discovery; webinar recordings on data and materials augmentation platforms, and more.
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New COVID-19 Infographics Explain the Terms Behind the Research
SLAS
SLAS created a series of infographics to explain, in simple terms, some common research concepts related to the current COVID-19 pandemic. These infographics help and break down the science behind the research and diagnosis of the virus. Each infographic is easily available for download and we encourage readers to share with their networks, family and friends. More infographics and resources will be added as they become available.
ACCESS COVID-19 RESOURCES PAGE
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Tim Spicer Named SLAS Discovery Associate Editor
SLAS
SLAS Discovery welcomes Timothy Spicer, Ph.D. (Scripps Research) as its new Associate Editor. Spicer joins Editor-in-Chief Robert Campbell, Ph.D. and fellow Associate Editors Marc Bickle, Ph.D. and Kirti Sharma, Ph.D. on the SLAS Discovery editorial leadership team. In this role, Spicer will support Dr. Campbell by contributing strategic counsel and assisting in trend analysis and journal management initiatives. Spicer is the Senior Scientific Director in the Department of Molecular Medicine at Scripps Research (FL, USA). Congratulations!
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The coronavirus (COVID-19) is a rapidly evolving threat, and the synthetic DNA that can help discover a vaccine and treatment is needed now — not in eight to ten weeks. SGI-DNA is supporting front-line researchers in combating the spread of COVID-19 by offering $50,000 in co-funding for the BioXp™ 3200 system.
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Save the Date: 2020 SLAS Building Biology in 3D Symposium
SLAS
Join SLAS and Scripps Research (Jupiter, FL, USA) for the 2020 SLAS Building Biology in 3D Symposium (November 17-18). This two-day event will address the successes and limitations of using 3D systems in discovery and applied research, while also acknowledging the need for further exploration into what improvements can be made to ensure approaches can be more widely adopted. More specifically, topics will include current and near-future enabling technologies, applications of such systems in high-throughput screening, advances in imaging and analysis of data generated in these systems and the expansion into novel model systems. Registration information and sponsorship and exhibit opportunities will be available soon.
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Promoted by
Thermo Scientific
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DNA Could Hold Clues to Varying Severity of COVID-19
The Scientist
Among the many mysteries that remain about COVID-19, the disease caused by the new coronavirus, is why it hits some people harder than others. Millions of people have been infected, but many never get sick. Those who do can experience an ever-expanding array of symptoms, including loss of smell or taste, pink eye, digestive issues, fever, cough, and difficulty breathing.
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Adding the Missing Sugars to Coronavirus Protein Structures
Chemical & Engineering News
Protein structures solved by cryo-electron microscopy x-ray crystallography often miss the sugar molecules known as glycans that cover large swaths of the molecules’ surfaces. The recently reported structures of the spike protein on SARS-CoV-2, the novel coronavirus that causes COVID-19, are no different. Researchers are now working to fill in some of those sugary blanks to better understand the virus’s biology and to help drugmakers develop vaccines and treatments.
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Antibiotic Treatment for COVID-19 Complications Could Fuel Resistant Bacteria
Science Magazine
In her regular job, Priya Nori runs Montefiore Medical Center’s antibiotic stewardship program, and spends most of her time ensuring that the Bronx-based hospital doesn’t overuse the drugs and allow bacteria resistant to them to thrive. But like many physicians, Nori is now spending all of her time helping treat COVID-19 patients at her New York City hospital, which like other medical centers in the pandemic hot spot, is crowded with 50% more patients than normal.
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COVID-19 Researchers Develop Tech for Mopping Up Cytokines, and Consider Gathering in the NETs
Genetic Engineering & Biotechnology News
While recent research has shown how the body can mount an effective immune response against SARS-CoV-2 in mild to moderate cases of COVID-19, scientists are now considering how to tackle the effects of immune system overreaction, such as the cytokine release syndrome, or cytokine storm, which can trigger severe lung damage and potentially lead to acute respiratory distress syndrome and death, as well as the less well know phenomenon of neutrophil extracellular traps.
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Smashing the Limits of Super-Resolution Microscopy
Lab Manager
University of New South Wales medical researchers have achieved unprecedented resolution capabilities in single-molecule microscopy to detect interactions between individual molecules within intact cells.
The 2014 Nobel Prize in Chemistry was awarded for the development of super-resolution fluorescence microscopy technology that afforded microscopists the first molecular view inside cells.
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Supercomputers and Archimedes' Principle Enable Calculating Nanobubble Diffusion in Nuclear Fuels
Phys.org
Researchers from the Moscow Institute of Physics and Technology have proposed a method that speeds up the calculation of nanobubble diffusion in solid materials. This method makes it possible to create significantly more accurate fuel models for nuclear power plants. During reactor operation, fission fragments, flying at high speeds through the crystal lattice of the nuclear fuel material, create various defects — vacancies, interstitial atoms, and their clusters.
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Micro-Device to Detect Bacteria, Viruses
Science Daily
Engineering researchers developed a next-generation miniature lab device that uses magnetic nano-beads to isolate minute bacterial particles that cause diseases. Using this new technology improves how clinicians isolate drug-resistant strains of bacterial infections and difficult-to-detect micro-particles such as those making up Ebola and coronaviruses.
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Employers: Search résumés, post an open position, internship or post-doc opportunity. SLAS Premier and Corporate Members get a discount on all new job postings.
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US – IA – Ames
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