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  Mobile version   RSS   Subscribe   Unsubscribe   Archive   Media Kit Apr. 24, 2013

SLAS.org    SLAS2014    Moving? New job? Let SLAS know.    

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SLAS Offers Valuable Student Memberships

Benefit from scientific education, information resources, career-building opportunities and industry and peer networking.



SLAS awards $10,000 cash prize

The SLAS Innovation Award recognizes the work behind that one unique and special presentation at SLAS2014.


 

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Laboratory Purchasing Trends study: take a peek inside
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Gain insight to findings from the 2013 North American Survey of Laboratory Purchasing Trends in the latest feature article in the SLAS Electronic Laboratory Neighborhood e-zine. The full 289-page report is available free to SLAS dues-paid members and includes responses and analyses related to personnel, workload, outsourcing, budgets and new laboratory building plans. Responses are cross tabulated by various market segments such as industry, hospital, government, college/university and independent/contract laboratory and specific product/service areas like basic research, biotechnology, chemicals, clinical, environmental and pharmaceutical. More

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Manuscript proposals due May 1 for JBS special issue on Knowledge from Small-Molecule Screening & Profiling Data
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Manuscript proposals related to the production, integration, analysis and mining of large datasets relevant to biological discovery, including chemical genomics, network biology and phenotypic drug discovery are being accepted until May 1. Invited authors will be notified of acceptance by May 13 and will need to submit final manuscripts and related materials by Aug. 15. More

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SLAS Endowed Fellowship team making progress
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The UCLA laboratory of Professor Dean Ho, supported in part by the SLAS Endowed Fellowship, has developed a potentially more effective treatment for "triple-negative" breast cancer using nanodiamonds. Study findings were published this month in Advanced Materials, “Diamond-Lipid Hybrids Enhance Chemotherapeutic Tolerance and Mediate Tumor Regression.” Lead co-authors are Edward K. Chow, Cancer Science Institute of Singapore and JALA associate editor/Asia and Laura Moore, a graduate student in Ho’s UCLA laboratory. More

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SLAS2014 is accepting presentation abstracts until Aug. 5
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Research scientists, engineers, academics and business leaders wishing to present their work at SLAS2014, the leading educational event for laboratory science and technology professionals, are invited to submit abstracts by Monday, Aug. 5. The seven SLAS2014 educational tracks are Assay Development and Screening, Automation and High-Throughput Technologies, Drug Target Biology, Micro/Nano Technologies, Bioanalytical Techniques, Informatics and Diagnostics and Biomarkers. More

JALA Online features new manuscripts ahead-of-print
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"A Computational Method for Planning Complex Compound Distributions under Container, Liquid Handler, and Assay Constraints" and "Isolation of Motile Spermatozoa with a Microfluidic Chip Having a Surface-Modified Microchannel" are among the new manuscripts available only to SLAS Laboratory Automation Section members ahead of print. More


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The Distance of the Moon: Radiolab latest podcast
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SLAS2014 keynote speakers Jad Abumrad and Robert Krulwich showcase Italo Calvino's story from Cosmicomics, "The Distance of the Moon." Cosmicomics feature imaginative stories built around a scientific notion, usually told by the character Qfwfq. Here, Calvino builds his story around the fact that the Moon used to be much closer to the Earth, and using a ladder, people could easily travel between them. More

Did you miss last week's SLAS Webinar?
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"Lessons Learned in Pharma – CRO Collaboration in Discovery Research" presented by Jonathan Connick of Merck is now available as an on-demand recording FREE to SLAS dues-paid members. The next live webinar in the "Effectively Managing Collaborative Science" series is May 15 – "Challenges and Strategies for Successful Transfer of Cell-Based Potency Assays," from Liming Shi of Eli Lilly. More

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Thomson Reuters identifies 100 key scientific research fronts
Thomson Reuters via Lab Manager    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The IP & Science business of Thomson Reuters, the world's leading provider of intelligent information for businesses and professionals, has released a report, "Research Fronts 2013: 100 Top Ranked Specialties in the Sciences and Social Sciences," identifying 100 important research areas across multiple fields of science. By examining highly cited research papers from 2007 through 2012, Thomson Reuters identified research fronts built on recently published "core," or foundational, journal articles. More

2 landmark studies report on success of using image-guided brachytherapy to treat cervical cancer
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Two large, landmark radiotherapy studies have shown that it is possible to treat cervical cancer effectively with high doses specifically adapted to each tumor, and with fewer serious side-effects to the surrounding normal organs. Researchers say that image-guided brachytherapy is able to deliver very high doses, which prevent the tumor from growing in over 90 percent of patients, with few serious side-effects. More


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Stunning 3-D sperm images reveal new motion
Live Science    Share    Share on FacebookTwitterShare on LinkedinE-mail article
A research team, led by SLAS2012 speaker and 2012 Innovation Award finalist Aydogan Ozcan, has announced the discovery of an entirely new pattern of movement for a familiar microscopic swimmer: sperm. In specimens from both humans and horses, the researchers were able to track thousands of cells at once to identify a sperm swimming pattern they had never before seen. The unusual, coiled-ribbon pattern was significantly more complex than sperm swimming patterns they observed last year, all findings that could have implications for fertility, health and our understanding of the microscopic world. More

Scientists map all possible drug-like chemical compounds
ScienceDaily    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Drug developers may have a new tool to search for more effective medications and new materials. It's a computer algorithm that can model and catalogue the entire set of lightweight, carbon-containing molecules that chemists could feasibly create in a lab. The small-molecule universe has more than 10^60 (that's 1 with 60 zeroes after it) chemical structures. Duke chemist David Beratan said that many of the world's problems have molecular solutions in this chemical space, whether it's a cure for disease or a new material to capture sunlight. More



Single cell antimicrobial susceptibility testing by confined microchannels and electrokinetic loading
Analytical Chemistry    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Multidrug-resistant pathogens are an emerging global health problem. In addition to the need of developing new antibiotics in the pipeline, the ability to rapidly determine the antibiotic resistance profiles of bacteria represents one of the most crucial steps toward the management of infectious diseases and the prevention of multidrug-resistant pathogens. Here, we report a single cell antimicrobial susceptibility testing approach for rapid determination of the antibiotic resistance of bacterial pathogens. More

Temperature-dependent radiolysis reveals dynamics of bound protein waters
Phys.org    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Water is crucial to the functioning of the body, even on very small scales. The ubiquitous liquid is key to the structure, folding and stability of proteins, but one of the still unanswered questions in the study of the structure and function of proteins and DNA is their exact relationship to their water environment. All of the molecules in our bodies function in water, but until now, we haven't had a lot of experimental techniques to understand what water is doing or where it is binding to the interior surfaces of proteins. More

Synthetic malaria drug could stem resistance
NewScientist    Share    Share on FacebookTwitterShare on LinkedinE-mail article
It's a triumph for malaria treatment, but bad news for farmers. A synthetic version of the world's most effective antimalarial drug, artemisinin, can now be made in just three weeks rather than 18 months. The advance could help to stem the rise of drug-resistant malaria. Amyris, a California-based biotech company, has developed a way to get yeast to pump out artemisinic acid, the precursor to artemisinin, rather than extracting it from the sweet wormwood plant. Drug firm Sanofi then turns the acid into a drug. More


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Aromatic sulfonyl fluorides covalently kinetically stabilize transthyretin to prevent amyloidogenesis while affording a fluorescent conjugate
Journal of the American Chemical Society    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Molecules that bind selectively to a given protein and then undergo a rapid chemoselective reaction to form a covalent conjugate have utility in drug development. Herein a library of 1,3,4-oxadiazoles substituted at the 2 position with an aryl sulfonyl fluoride and at the 5 position with a substituted aryl known to have high affinity for the inner thyroxine binding subsite of transthyretin (TTR) was conceived of by structure-based design principles and was chemically synthesized. More

Porous framework compound may work to extract uranium from seawater
Chemical & Engineering News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The world's oceans hold nearly 1,000 times more uranium than all known land-based sources. The total, an estimated 4 billion metric tons, could supply the nuclear power industry's fuel needs for centuries, even if the industry grows rapidly. But until now, few studies have addressed the difficulties of extracting low concentrations of the dissolved metal from the sea. More

Amazing new technological advances in healthcare
By Rosemary Sparacio    Share    Share on FacebookTwitterShare on LinkedinE-mail article
It probably does not surprise anyone just how much technology has affected our daily lives. But the impact of technology in healthcare has been and continues to be nothing short of astounding. And there is always more to come. At the Society of Interventional Radiology's 38th Annual Scientific Meeting, three new treatment advances were discussed: irreversible electroporation, cryoablation and cryoneurolysis. Here is a closer look at what each has to offer. More


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Career


Bioautomation Engineer I
The Broad Institute
USA – MA – Cambridge

Sr. Specialist/Advisor – Corrosion & Materials
Albemarle Corporation
USA – LA – Baton Rouge

QC Senior Scientist – Commercial
Genentech
USA – CA – South San Francisco

More jobs at SLAS Career Connections


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