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  Mobile version   RSS   Subscribe   Unsubscribe   Archive   Media Kit Apr. 25, 2012

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SLAS accepting applications for SLAS2013 student travel awards
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July 30 is the deadline for students, graduate students, post-doctoral associates and junior faculty to submit podium abstracts and opt in to be considered for a Tony B. Academic Travel Award. Poster abstracts will be accepted until Sept. 17. The awards, which include airfare, registration and shared hotel accommodations for selected students, honor Association for Laboratory Automation Co-Founder Tony Beugelsdijk of Los Alamos National Laboratory, who passed away in August 2009. More

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What is a good assay for validating an automated serial dilution?
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This question posed by Steve Maxwell of Myla Technologies, Inc. on SLAS LinkedIn has been generating interesting discussion. Jump in with your thoughts! It is one of several questions, article links and SLAS news items posted on the 3,000-plus member SLAS social media site. More



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The SLAS community helps one another
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Thanks to Holly, Maty, Erin and Karin, who added their ideas for how to handle a demanding career in science with other interests and priorities in the comments section of the SLAS ELN feature, "Negotiating Work and Life: How to Find the Joy." Check the tips offered and add yours to the discussion. More

Theodore Gray releases the Elements Vault
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The Elements Vault picks up where The Elements left off with all new text, new photographs and even more sparkling information about the elements. One reviewer states about this featured LabAutopedia book of the month: "I don't know if this is the first coffee-table book paying lush photographic homage to the periodic table, but it is certainly the most gorgeous one I've seen." More


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Sir Harold Kroto added to Encyclopaedia Britannica
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This SLAS2013 keynote speaker's online listing reads "... English chemist who, with Richard E. Smalley and Robert F. Curl, Jr., was awarded the 1996 Nobel Prize for Chemistry for their joint discovery of the carbon compounds called fullerenes." Kroto, now with Florida State University, will be one of three keynote speakers at SLAS2013 in Orlando, Fla., on Tuesday, Jan. 15. MORE More

Two win registration to 2012 SLAS Asia Conference and Exhibition
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Congratulations to Qingyu Lang, Abbott R&D Center Shanghai, and Honghai Ge, Bio-Gene China, who each won a registration to the 2012 SLAS Asia Conference and Exhibition by completing a recent member survey from the SLAS Asia Office. More

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Next big step for high-throughput ADME
Drug Discovery & Development    Share    Share on FacebookTwitterShare on LinkedinE-mail article
When considering the present use — and future potential — of high-throughput absorption, distribution, metabolism and excretion (HT-ADME) assays, it is important to understand the context. "Generally, when people refer to high-throughput, they mean screening tens of thousands of compounds at a time," says Ron White, PhD, senior vice president for DMPK science and technology, XenoBiotic Laboratories. More

An engineered eukaryotic protein glycosylation pathway in Escherichia coli
Nature Chemical Biology    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The authors performed bottom-up engineering of a synthetic pathway in Escherichia coli for the production of eukaryotic trimannosyl chitobiose glycans and the transfer of these glycans to specific asparagine residues in target proteins. The glycan biosynthesis was enabled by four eukaryotic glycosyltransferases, including the yeast uridine diphosphate-N-acetylglucosamine transferases Alg13 and Alg14 and the mannosyltransferases Alg1 and Alg2. More


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Investigate major signaling pathways
Cisbio provides a panel of cellular kinase assays dedicated to the measurement of site-specific phosphorylation, in an endogenous cellular environment. These homogeneous assays represent a reliable, robust and rapid alternative to classical technologies like Western Blot, ELISA or bead-based assays.
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Microscopy yields first proof of ferroelectricity in simplest amino acid
Lab Manager    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The boundary between electronics and biology is blurring with the first detection by researchers at Department of Energy's Oak Ridge National Laboratory of ferroelectric properties in an amino acid called glycine. A multi-institutional research team used a combination of experiments and modeling to identify and explain the presence of ferroelectricity, a property where materials switch their polarization when an electric field is applied, in the simplest known amino acid — glycine. More

A chemical genetic approach for covalent inhibition of analogue-sensitive aurora kinase
ACS Chemical Biology    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The perturbation of protein kinases with small organic molecules is a powerful approach to dissect kinase function in complex biological systems. Covalent kinase inhibitors that target thiols in the ATP binding pocket of the kinase domain proved to be ideal reagents for the investigation of highly dynamic cellular processes. More



Firms trying to untangle Alzheimer drug development with mAbs
Genetic Engineering & Biotechnology News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
On April 10, the FDA approved Lilly's Amyvid (florbetapir F 18 injection) as a PET imaging reagent to be used in adults who are being evaluated for Alzheimer disease and other causes of cognitive decline. Lilly gained Amyvid through its acquisition of Avid Radiopharmaceuticals in 2010 for an up-front payment of $300 million. Avid stockholders are eligible to receive up to $500 million contingent upon regulatory and commercial milestones. More

Measles deaths have plummeted over a decade
Bioscience Technology    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The number of measles deaths worldwide has apparently dropped by about three-quarters over a decade, according to a new study by the World Health Organization and others. Most of the deaths were in India and Africa, where not enough children are being immunized. Health officials estimate about 9.6 million children were saved from dying of measles from 2000 to 2010 after big vaccination campaigns were rolled out more than a decade ago. More


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Dynamic causes of relation between area and age of ocean floor
Science Magazine    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The distribution of seafloor ages determines fundamental characteristics of Earth, such as sea level, ocean chemistry, tectonic forces and heat loss from the mantle. The present-day distribution suggests that subduction affects lithosphere of all ages, but this is at odds with the theory of thermal convection that predicts that subduction should happen once a critical age has been reached. More

Researchers ID psoriasis predisposition gene
GenomeWeb     Share    Share on FacebookTwitterShare on LinkedinE-mail article
Mutations in the NF-kappaB activator-coding gene CARD14 have been linked to the most common form of psoriasis and appear to contribute to other manifestations of the disease as well, according to a Washington University-led team. The researchers described their findings in a pair of studies online in the American Journal of Human Genetics. More

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Clues to aspirin's anti-cancer effects revealed
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One of the world's oldest medicines may hold the secret to a very contemporary problem: preventing cancer. Exactly why salicylate shows such potential as an anti-cancer treatment remains unclear, but a new study in mice offers clues. Salicylate, found in willow bark, has been a key ingredient in medicine cabinets for thousands of years — ancient Egyptian manuscripts describe it as a treatment for inflammation. More

Top DNA sequencing company evades Roche's takeover
Technology Review    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Roche Holding, one of the largest healthcare companies in the world, is bidding high for San Diego-based Illumina, manufacturer of the most widely used high-throughput DNA sequencing machines. Illumina's shareholders have so far rebuffed Roche's all-cash offers, which have grown to $6.8 billion in recent weeks, claiming that they underestimate the potential value of the company. More

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Super Salmonella bacteria found
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Certain Salmonella bacteria, the microbes that cause food poisoning, have the potential to become as much as 100 times more virulent than normal, recent research has found. In the study, these super-bugs overcame the protective effects of a Salmonella vaccine, killing vaccinated mice. The scientists found that some of the bacteria have the potential to become much nastier than others. More

An improved tool for nuclear forensics
Science & Technology Review    Share    Share on FacebookTwitterShare on LinkedinE-mail article
In the aftermath of an aboveground nuclear explosion, measuring the isotopic compositions of fallout can provide important forensic information, including data pertaining to the production and irradiation histories of key materials. Livermore scientists working with collaborators at Argonne National Laboratory and the University of California at Berkeley have recently demonstrated rapid and high-accuracy isotopic measurements of plutonium and uranium using a laser-based technique. More


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Get your free automation consultation
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Career


Automation Scientist
Promega Corporation
USA – WI – Madison

Sr. Director, Nonclinical Pharmacology and Toxicology
XOMA Corporation
USA – CA – Berkeley

Product Development Engineer
Confidential Biomedical Company
USA – IL – North Chicago

More jobs at SLAS Career Connections


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