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SLAS
Research scientists, engineers, academics and business leaders are invited to submit podium and poster abstracts for presentation at the 2019 SLAS International Conference and Exhibition, Feb. 2-6, in Washington, DC. The Scientific Program Committee soon will be accepting abstract submissions that describe original research and will be assessed according to the novelty of the work with an emphasis on abstracts that clearly detail results relating to the conference's 10 educational tracks.
Students: Watch for information regarding the SLAS Tony B. Academic Travel Award, which brings students, graduate students, post-doc researchers and junior faculty members to SLAS2019 to present their scientific achievements.
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SLAS
SLAS is seeking to recruit a highly accomplished and experienced scientist to serve as its scientific director. Candidates must be thought leaders within the SLAS scientific community and have familiarity with the work of related organizations. The position calls for an innovative senior scientist who possesses a broad working knowledge of the various disciplines represented in the SLAS community, including basic science, translational research, drug discovery and development, clinical research, informatics and laboratory automation.
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SLAS
A new article from SLAS President Sabeth Verpoorte, Ph.D., in the SLAS Electronic Laboratory Neighborhood (SLAS ELN) highlights the 2018 SLAS Europe Conference and Exhibition. "We've incorporated all we have learned about quality education and networking from the annual SLAS International Conference and Exhibition and added flavor of the region to offer this inaugural event June 27-29 at the spectacular Square Brussels Meeting Centre in Brussels, Belgium," says Verpoorte.
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Because drug discovery involves scientists from multiple disciplines and often organizations, it is critical to have an efficient mechanism for researchers to collaborate and realize the collective value of their specialized knowledge, assets, and capabilities. This free white paper details the essential keys to effective collaboration.
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SLAS
Register now for Using AI and IoT to Accelerate Research, an upcoming SLAS Webinar featuring Sridhar Iyengar, Ph.D., CEO and founder of Elemental Machines (Cambridge, MA, USA). Using subject matter from his highly attended SLAS2018 presentation as a launching point, Iyengar will discuss how technologies such as artificial intelligence/machine learning (AI/ML) and the Internet of Things (IoT) can accelerate scientific research. The SLAS Webinar, which is free to SLAS Premium members, will be presented live from 12:00-1:00 p.m. CT (1:00-2:00 p.m. ET, 10:00-11:00 a.m. PT) on May 8 and later on demand.
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SLAS
ScholarOne Manuscripts (a.k.a. SLAS Discovery and SLAS Technology SAGE Track) will transition to Amazon Web Services in late May. To ensure uninterrupted e-mail delivery, please have your IT team add these domains — amazonses.com and manuscriptcentral.com — to your Safe Senders List.
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SLAS
Save up to €80 when you register before July 31 for the 2018 SLAS Advanced 3D Human Models and High-Content Analysis Conference to be held Oct. 17-19 in Leiden, Netherlands. The scientific program will focus on novel achievements in 3D culture enabling technologies, applications of high-throughput microscopy and multiparametric analysis (high-content screening), advances in imaging and analysis of biological samples, and opportunities for stem cells and organoids.
Attention life sciences discovery and technology vendors and service providers: Great sponsorship opportunities are available for this event!
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Chemical & Engineering News
The enzyme telomerase, which restores chromosome ends shortened by cell division, was discovered over three decades ago, but no view of the human enzyme at atomic resolution, approximately 3 Å, has been captured. The problem is that telomerase is present in cells in tiny quantities and is not easily purified. Now, using refined purification methods, researchers have taken a giant leap toward the atomic-resolution goal.
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AMRI’s integrated drug discovery centers of excellence combine scientific expertise and leading-edge technology to accelerate innovation. Our complete suite of solutions includes comprehensive discovery biology, synthetic and medicinal chemistry, DMPK and bioanalytical services for successful hit-to-lead-to-candidate selection.
Contact us to put our Discovery expertise to work for you, contact: Customerservice@amriglobal.com.
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Bioscience Technology
It's DNA, but not as we know it.
In a world first, Australian researchers have identified a new DNA structure — called the i-motif — inside cells. A twisted "knot" of DNA, the i-motif has never before been directly seen inside living cells.
The new findings, from the Garvan Institute of Medical Research, are published in the leading journal Nature Chemistry.
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Developments in laboratories evolve rapidly and create a demand for flexible and modular robotic automation systems. For this purpose: Lab Services developed the PlateButler® Pier & BarQ: a flexible modular solution to dock and undock devices onto your PlateButler® Robotic System. So key devices can be shared over the different applications in the lab.
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Analytical Chemistry
Inspired by the recognition processes found in biology such as enzyme–substrate and antibody–antigen interactions, synthetic systems with comparable molecular recognition properties have been investigated during recent years based on molecular imprinting strategies. While materials with recognition capabilities for small molecules have achieved substantial advancements, the synthesis of molecularly imprinted materials with virus recognition properties remains challenging to date.
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Journal of the American Chemical Society
Lipid droplets are intracellular lipid-rich organelles that regulate the storage of neutral lipids and were recently found to be involved in many physiological processes, metabolic disorders, and diseases including obesity, diabetes, and cancers. Herein we present a family of new fluorogenic merocyanine fluorophores based on an indolenine moiety and a dioxaborine barbiturate derivative.
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Science Daily
In the future, materials scientists will use advanced software to specify the properties they desire and a program will deliver a choice of optimized chemical compounds.
Dr. B. Christopher Rinderspacher, a theoretical chemist with the U.S. Army Research Laboratory, recently published a paper describing the process of using mathematics to design chemical compounds by reducing complexity and taking advantage of machine learning.
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Phys.org
In the world of chemistry, good things can happen if you just add sugar. A wide range of drugs and biochemical probes — everything from antibiotics to Alzheimer's disease biomarkers — rely on natural or synthetic compounds that aid a reaction by adding carbohydrates. It's a process called glycosylation. But it is traditionally a highly specific process that makes synthesis of such compounds, for testing or large-scale production, difficult.
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Genetic Engineering & Biotechnology News
The link between cancer mutations and DNA repair mechanisms has been well established. However, the specific origins of the mutation in these essential pathways have remained enigmatic. Now, researchers at the European Bioinformatics Institute, the University of Dundee and the Wellcome Sanger Institute have utilized human and worm data to explore the mutational causes of cancer.
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Lab Manager
As many as one in three women treated for breast cancer undergo unnecessary procedures, but a new method for diagnosing it could do a better job distinguishing between benign and aggressive tumors.
Researchers at the University of Michigan are developing a pill that makes tumors light up when exposed to infrared light, and they have demonstrated that the concept works in mice.
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Field Application Scientist (FAS) - US
Promega Corporation
North America
Field Application Scientist - Europe
Promega Corporation
UK
Scientist, High Throughput Protein Expression (non PhD)
Pfizer
US – MA – Cambridge
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