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Erik Werner Earns First SLAS Graduate Education Fellowship Grant
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Werner is a graduate student and Ph.D. candidate in the Hui Lab at the University of California, Irvine. The SLAS grant provides $100,000 over two years to help Werner develop a droplet array containing millions of compartmentalized and indexed droplets with a micro scale valve system to enable addressable release of individual droplets on demand. Using this device, reaction volumes in a typical screening assay can be reduced more than 100 fold, greatly decreasing the cost of each library screen.

"Erik was selected based on a number of accomplishments at the undergraduate and graduate level," said Susan Lunte, University of Kansas, chair of the SLAS Graduate Education Fellowship Grant Review Panel. "We had a number of excellent proposals and candidates, and Erik rose above." SLAS will begin accepting applications for 2017 in the fall of 2016.
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JALA Special Issue Call for Papers: Personalized and Precision Medicine
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Guest Editors Dean Ho and Ali Zarrinpar of UCLA invite manuscript proposals (abstracts) of original research and review papers for this JALA special issue to be published in the summer of 2017. Proposals are due by June 1, 2016.

Topics of interest include combination therapy development technologies; genome-based drug discovery; high-throughput screening and drug development; immunotherapy; imaging; single cell analysis technologies; robotics and automation; and personalized and precision medicine in cancer, infectious diseases, transplantation, cardiology, surgery, regenerative medicine, pediatrics, global health, natural products and other clinical specialties.
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New Original Research on JBS Online Ahead-of-Print
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  • Simultaneous High-Throughput Conformational and Colloidal Stability Screening Using a Fluorescent Molecular Rotor Dye, 4-(4-(Dimethylamino)styryl)-N-Methylpyridinium Iodide (DASPMI)
  • Morphological Evaluation of Nonlabeled Cells to Detect Stimulation of Nerve Growth Factor Expression by Lyconadin B (Japan)
  • In Vivo Chemical Screen in Zebrafish Embryos Identifies Regulators of Hematopoiesis Using a Semiautomated Imaging Assay (Germany)
  • Ranking Differential Drug Activities from Dose-Response Synthetic Lethality Screens (U.S.)
  • Development of a Multiplex Assay for Studying Functional Selectivity of Human Serotonin 5-HT2A Receptors and Identification of Active Compounds by High-Throughput Screening (Spain)
  • 384-Well Multiplexed Luminex Cytokine Assays for Lead Optimization (U.S.)
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From the LabAutopedia Book List: Life's Greatest Secret — The Story of the Race to Crack the Genetic Code
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Professor of zoology at Manchester University and two-time book author Matthew Cobb takes us beyond the usual names associated with DNA like Watson, Crick, Franklin, and tells the stories of numerous others working hard to capture the information within DNA that controls the proteins in living cells.

As noted in a book review in The Guardian, "there was no centralized, coordinating organization running the race: nothing like the Manhattan Project, or the Human Genome Project, just competing laboratories in the U.S., Britain and France and the international system of scientific publication."
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Job Seekers and Employers Connect via SLAS Career Connections
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Visit this targeted employment exchange regularly to keep up to date with job opportunities such as research scientist, high-throughput analysis; senior research scientist, automation specialist; product manager, automation; discovery bioassets global lead; and scientist III.

Job seekers can post resumes and browse job openings for free. Employers can find new talent by reviewing posted resumes for free and attract new talent by posting job openings for a fee. Note: SLAS Corporate Members receive a 50% discount on job postings.
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Bioengineers Create First Online Search Engine for Functional Genomics Data
Bioscience Technology    Share    Share on FacebookTwitterShare on LinkedinE-mail article
University of California San Diego bioengineers have created what they believe to be the first online search engine for functional genomics data. This work from the Sheng Zhong bioengineering lab at UC San Diego was just published online by the journal Nucleic Acids Research. This new search engine, called GeNemo, is free for public use. GeNemo addresses a pressing challenge: effectively searching functional genomic data from online data repositories. More


Electronic Micro Labs Control Chemical Processes From the Inside
Science Daily    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Chemists at the Ruhr-Universität Bochum, together with their project partners, have developed tiny electronic components that can control chemical processes from the inside. These micro labs are 140 x 140 x 60 micrometers small. They can sense their environment and control chemistry via voltage signals. More


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State-of-the-Art Metabolic Toxicity Screening and Pathway Evaluation
Analytical Chemistry    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Routine in vitro bioassays and animal toxicity studies of drug and environmental chemical candidates fail to reveal toxicity in ∼30% of cases. This feature article addresses research on new approaches to in vitro toxicity testing as well as our own efforts to produce high-throughput genotoxicity arrays and LC−MS/MS approaches to reveal possible chemical pathways of toxicity. More


A New Model for Simulating DNA's 'Atmosphere' of Ions
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Nucleic acids, large biomolecules essential to life, include the familiar double-stranded deoxyribonucleic acid (DNA), a very stable long molecule that stores genetic information. In nature, DNA exists within a solution rife with electrostatically charged atoms or molecules called ions. A recent study proposed a new model of how B-DNA, the form of DNA that predominates in cells, is influenced by the water-and-ions "atmosphere" around it. More




Structure and Function of a Bacterial Microcompartment Shell Protein Engineered to Bind a [4Fe-4S] Cluster
Journal of the American Chemical Society    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Bacterial microcompartments are self-assembling organelles composed of a selectively permeable protein shell and encapsulated enzymes. They are considered promising templates for the engineering of designed bionanoreactors for biotechnology. In particular, encapsulation of oxidoreductive reactions requiring electron transfer between the lumen of the BMC and the cytosol relies on the ability to conduct electrons across the shell. More


Chemists Introduce a User's Guide for Palladium Acetate
Chemical & Engineering News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Palladium is the king of transition-metal catalysts. It earned the title, along with a Nobel Prize, because of its versatility in catalyzing C–H bond activation and cross-coupling reactions of many different types of organic molecules to make pharmaceuticals, agrochemicals, and electronic materials. But no king is infallible. Commercially available palladium acetate, the most popular precursor for preparing active palladium catalysts, often contains several structurally similar impurities. More


Dog Genome Studies Provide Insights on Human Diseases
Genetic Engineering & Biotechnology News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
An important model in studying human disease, the noncoding RNA of the canine genome is an essential starting point for evolutionary and biomedical studies according to a study ("An Improved microRNA Annotation of the Canine Genome") published in PLoS ONE and led by the U.K.-based The Genome Analysis Centre. The research reveals an improved annotation of microRNAs in the dog genome to understand their biological role further. More


Gene Therapy Shows Long-Term Benefit for Treating Rare Blindness
Lab Manager    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Pioneering gene therapy has restored some vision to patients with a rare form of genetic blindness for as long as four years, raising hopes it could be used to cure common causes of vision loss, new University of Oxford research shows. A technique which involves injecting a virus into the eye to deliver billions of healthy genes to replace a key missing gene for choroideremia sufferers has provided sustained improvement in vision for up four years for some patients. More


Career


Research Scientist – High-Throughput Analysis
UES, Inc.
US – OH – Dayton

Senior GMP Quality Assurance Specialist
STEMCELL Technologies Inc.
CA – Vancouver

MGH In Vivo Microscopy (IVM) Fellowship
Tearney Lab
US – MA – Boston

Search Jobs at SLAS Career Connections


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