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  Mobile version   RSS   Subscribe   Unsubscribe   Archive   Media Kit May. 8, 2013

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May 15 SLAS Webinar: Challenges and Strategies for Successful Transfer of Cell-Based Potency Assays
SLAS    Share    Share on FacebookTwitterShare on LinkedinE-mail article
"Setting up the appropriate expectations and getting the aligned scope at the beginning are very important," says Liming Shi of Eli Lilly, presenter for the May 15 SLAS Webinar. "I would like every attendee of the webinar to understand that bioassay transfer is a complicated process with multiple steps that require thorough technical expertise and acute management skills. However, with rock solid scientific knowledge, complete training and project management expertise, it can be done effectively. The webinar will include real examples to demonstrate the tricky parts and loopholes during the transfer business." The webinar is free to SLAS dues-paid members. More

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2013 SLAS Asia Conference and Exhibition welcomes poster submissions
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May 21 is the final deadline for poster submissions for the June 5-7 SLAS Asia Conference and Exhibition, Shanghai. Discuss your latest findings in drug discovery science and laboratory technology with the 450 expected participants at this third annual event, which also includes 25 scientific sessions, three optional short courses and an exhibition featuring 40 multinational companies. More

The Lab Man interviews new members of the SLAS Board of Directors
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The Lab Man talks with Joshua Bittker and Richard Ellson about their new volunteer roles. Ellson's goals include helping to expand the reach of the organization, bringing engineering and science together globally. Bittker wants to further SLAS's role as a forum for collaboration between those at all levels of research and discovery. Both board members stress the year-round opportunities available through SLAS, such as the internationally recognized peer-reviewed scientific journals. Dean Ho, the third new board member, was featured in a previous podcast by The Lab Man. More

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JALA Online features new manuscripts ahead-of-print
SLAS    Share    Share on FacebookTwitterShare on LinkedinE-mail article
"High-Throughput Quality Control of DMSO Acoustic Dispensing Using Photometric Dye Methods" and "High-Throughput RNA Interference Screening: Tricks of the Trade" are among the new manuscripts available ahead-of-print only to SLAS Laboratory Automation Section members. More

Welcome to the neighborhood!
SLAS    Share    Share on FacebookTwitterShare on LinkedinE-mail article
If you haven't been to the SLAS Electronic Laboratory Neighborhood e-zine lately, here's what you've been missing:
  • Member profiles: Ioana Popa-Burke, Al Kolb, Ying Yang
  • 2013 Laboratory Purchasing Trends study highlights
  • Chad Mirkin's groundbreaking work with spherical nucleic acids
  • Andy Zaayenga's latest LabAutopedia book review
More

Ensure your coworkers have instant online access to JALA and JBS
SLAS    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Encourage your company or university library to give your team full access to 18 years of original, peer reviewed research. JALA explores ways scientists adapt advancements in technology for scientific exploration and experimentation. JBS reports how scientists use adapted technology to pursue new therapeutics for unmet medical needs. Together they complete the laboratory science and technology continuum. Complete the JALA Institutional Subscription Recommendation Form or JBS Institutional Subscription Recommendation Form. More

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Turning off cancer's 'master regulator'
Genetic Engineering & Biotechnology News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Researchers have identified a gene that, when repressed in tumor cells, puts a halt to cell growth and a range of processes needed for tumors to enlarge and spread to distant sites. The Johns Hopkins researchers hope that this "master regulator" gene may be the key to developing a new treatment for tumors resistant to current drugs. More

Seeds of dementia: What do Alzheimer's, Parkinson's and Lou Gehrig's have in common?
Scientific American    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Under a microscope, a pathologist searching through the damaged nerve cells in a brain tissue sample from a patient who has died of Alzheimer's disease can make out strange clumps of material. They consist of proteins that clearly do not belong there. Where did they come from, and why are there so many of them? And most important, what do they have to do with this devastating and incurable disorder? More


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Iron spurs C–H bond reactivity
Chemical & Engineering News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Finding inspiration in the iron-based enzymes that metabolize drugs and other chemicals, chemists have come up with a catalyst that turns unreactive C–H bonds into useful C–N bonds. The transformation gives chemists rapid access to saturated heterocycles, which are common structural motifs in drugs and other biologically relevant molecules. More

New device can extract human DNA with full genetic data in minutes
Science Daily    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Take a swab of saliva from your mouth, and within minutes your DNA could be ready for analysis and genome sequencing with the help of a new device. University of Washington engineers and NanoFacture, a Bellevue, Wash., company, have created a device that can extract human DNA from fluid samples in a simpler, more efficient and environmentally friendly way than conventional methods. More

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Separation of dicarboxylic acids through molecular recognition and mechanochemistry
Phys.org    Share    Share on FacebookTwitterShare on LinkedinE-mail article
How does one separate a mixture of components with very similar properties? In the journal Angewandte Chemie, Croatian researchers have introduced a new approach to the separation of organic compounds. In their process, a "host compound" recognizes the desired "guest molecules," not only in solution, but also when the host and mixtures of competitive guest are milled together in the solid state. More

Sequencing study follows pneumococcal population dynamics after vaccine introduction
GenomeWeb    Share    Share on FacebookTwitterShare on LinkedinE-mail article
A new Nature Genetics study has taken a look at Streptococcus pneumoniae population patterns in Massachusetts in the years following the introduction of a vaccine targeting several pneumococcal infection-causing forms of the bug. Researchers from the Harvard School of Public Health, the Wellcome Trust Sanger Institute, Addenbrooke's Hospital at the University of Cambridge, and elsewhere did whole-genome sequencing on hundreds of S. pneumoniae isolates. The sample set represented samples collected between 2000 and 2007 in Massachusetts from individuals showing no obvious signs of infection. More


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A mononuclear non-heme manganese(IV)–oxo complex binding redox-inactive metal ions
Journal of the American Chemical Society    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Redox-inactive metal ions play pivotal roles in regulating the reactivities of high-valent metal–oxo species in a variety of enzymatic and chemical reactions. A mononuclear non-heme Mn(IV)–oxo complex bearing a pentadentate N5 ligand has been synthesized and used in the synthesis of a Mn(IV)–oxo complex binding scandium ions. The Mn(IV)–oxo complexes were characterized with various spectroscopic methods. More

Coming soon: A cure for gray hair?
Popular Science    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Researchers are working on a true anti-graying cream that could make people produce their own youthful colors again. So far, it's worked in just a few people who have lost pigment in their hair and skin not from age, but from a condition called vitiligo. Because the cause of vitiligo pigment loss is the same as one possible cause of graying in old age, however, the prototype cream might be a step toward a real anti-graying cream. More

Metaproteomics: Harnessing the power of high performance mass spectrometry to identify the suite of proteins that control metabolic activities in microbial communities
Analytical Chemistry    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The availability of extensive genome information for many different microbes, including unculturable species in mixed communities from environmental samples, has enabled systems-biology interrogation by providing a means to access genomic, transcriptomic, and proteomic information. To this end, metaproteomics exploits the power of high-performance mass spectrometry for extensive characterization of the complete suite of proteins expressed by a microbial community in an environmental sample. More



Hazardous drugs and worker safety: Emerging regulations
By Matthew D. Zock    Share    Share on FacebookTwitterShare on LinkedinE-mail article
California recently introduced Assembly Bill 1202 that would require its state Occupational Safety and Health Standards Board to promulgate a standard for hazardous drugs, which includes antineoplastic agents or "chemotherapy." If enacted, California will become the second state to regulate hazardous drug handling in the workplace, as the state of Washington passed a similar bill in 2011 that required its Department of Labor and Industries to adopt a hazardous drugs rule. More

Hidden cancer risks for women found in genome analysis
Bloomberg    Share    Share on FacebookTwitterShare on LinkedinE-mail article
An analysis of the most common uterine cancer suggests the disease should be reclassified into four categories that may help lead to more targeted treatments. About a quarter of a group of women who would be thought to have a favorable outcome under traditional diagnosis, or 10 percent of all patients, actually have genetic changes suggesting they have a more serious disease and may be in need of more aggressive treatment, according to the research in the journal Nature. More

Camouflage mismatch in seasonal coat color due to decreased snow duration
Proceedings of the National Academy of Sciences    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Most examples of seasonal mismatches in phenology span multiple trophic levels, with timing of animal reproduction, hibernation or migration becoming detached from peak food supply. The consequences of such mismatches are difficult to link to specific future climate change scenarios because the responses across trophic levels have complex underlying climate drivers often confounded by other stressors. More


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New Webinar: Recent Advances Using Continuous Flow Chemistry
METTLER TOLEDO     Share    Share on FacebookTwitterShare on LinkedinE-mail article
METTLER TOLEDO has launched the latest installment in its ongoing Recent Advances in Organic Chemistry free webinar series. In it, METTLER TOLEDO technology and applications specialist Dominique Hebrault, Ph.D. reviews several recent experiments in which mid-infrared spectroscopy, or mid-IR, enabled efficient continuous flow chemistry processes. In each case, inline monitoring combined with an integrated flow system was shown to offer significant time savings over traditional methods when performing critical reaction optimization studies. More

3-D living patch built for damaged hearts
Bioscience Technology    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Duke University biomedical engineers have grown three-dimensional human heart muscle that acts just like natural tissue. This advancement could be important in treating heart attack patients or in serving as a platform for testing new heart disease medicines. The "heart patch" grown in the laboratory from human cells overcomes two major obstacles facing cell-based therapies — the patch conducts electricity at about the same speed as natural heart cells and it "squeezes" appropriately. More

Nanoparticle tech could bring clean water to rural poor
LiveScience    Share    Share on FacebookTwitterShare on LinkedinE-mail article
A water purification system that uses nanotechnology to remove bacteria, viruses and other contaminants may be able to deliver clean drinking water to rural communities for less than $3 a year per family, according to a new study. Researchers at the Indian Institute of Technology Madras in Chennai, India, developed a purification device that filters water through a specially crafted mixture of nanoparticles to remove harmful contaminants. More


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BMG LABTECH Introduces The CLARIOstar
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Career


Senior Software Engineer
HighRes Biosolutions
USA – MA – Woburn

Senior Applications Specialist
IntelliCyt Corporation
USA – NM – Albuquerque

Bioautomation Engineer I
The Broad Institute
USA – MA – Cambridge

More jobs at SLAS Career Connections


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