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SLAS
Volunteers are the lifeblood of SLAS, and we couldn't do it without you! We've launched a new online Volunteer Center to make volunteering even easier. We are looking for dedicated SLAS members who are willing to give of their time and talents, in ways big and small. There will be open calls for committees in the future, but never will we have such a diverse set of options for you. Check out the Volunteer Center now and submit a volunteer form through May 25. We've made it easy for you to find the right match for your available time, interests and expertise. European volunteers: We will open your Call for Volunteers in July, right after the 2018 SLAS Europe Conference and Exhibition concludes.
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SLAS
"We want to understand the human building blocks of life to map the biomolecular parts list of humans," says Mathias Uhlén, Ph.D., a professor of microbiology and biotechnology at the KTH Royal Institute of Technology (Stockholm, Sweden). In a new article in the SLAS Electronic Laboratory Neighborhood (SLAS ELN), Uhlén reveals how his research became The Human Protein Atlas (HPA), a map of human proteins in cells, tissues and organs throughout the body. Uhlén also discusses his keynote presentation for the inaugural 2018 SLAS Europe Conference and Exhibition, in which he will share his new research pursuits into precision medicine.
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SLAS
NEW and FREE at SLAS Discovery: Authors of an article recently published in eLife ("LINE-1 Protein Localization and Functional Dynamics During the Cell Cycle") explain their general views on their novel discoveries and discuss ideas on the relevant new questions generated by their data in an auto-commentary. Paolo Mita, Ph.D., and Jef D. Boeke, Ph.D., of NYU Langone Health, employ genetic, biochemistry and imaging techniques to identify, characterize and ultimately employ the biological properties and the interactions of LINE-1 retrotransposons with mammalian cells. They added new pieces to the LINE-1 life-cycle puzzle, demonstrating the importance of the cell cycle in L1 cellular localization, activity, and surprisingly, revealing that the DNA replication complex is a possible new important regulator of LINE-1 activity.
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Because drug discovery involves scientists from multiple disciplines and often organizations, it is critical to have an efficient mechanism for researchers to collaborate and realize the collective value of their specialized knowledge, assets, and capabilities. This free white paper details the essential keys to effective collaboration.
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SLAS
The SLAS2019 Scientific Program Committee is now accepting abstract submissions for the next SLAS International Conference and Exhibition, Feb. 2-6, 2019, in Washington, DC. Life sciences discovery and technology professionals from academia, government and industry sectors are encouraged to submit podium and poster presentation abstracts for 10 educational tracks:
- Advances in Bioanalytics and Biomarkers
- Assay Development and Screening
- Automation and High-Throughput Technologies
- Biologics Discovery
- Cellular Technologies
- High Definition Biotechnology
- Data Analysis and Informatics
- Drug Target Strategies
- Micro- and Nanotechnologies
- Molecular Libraries
Students: Apply for an SLAS Tony B. Academic Travel Award when you submit your podium or poster abstract. The travel award application and podium abstract deadline is Monday, Aug. 6. The travel award and poster abstract deadline is Monday, Sept. 24.
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SLAS
Examine current topics and enhance your knowledge at the new 2018 SLAS Americas Sample Management Symposium: Managing Samples from Bench to Clinic, Nov. 13-14 in Boston, MA, USA. The symposium will delve into implementing new technologies associated with small molecule compound management laboratories, managing biologics, new modalities and biospecimens from clinical trials, establishing a biobank and exploring the new frontiers in compound management as they relate to drug discovery. Submit a Poster Abstract: Deadline for submissions is Aug. 27. Register now: Save up to $150 when you sign up by Oct. 1. Students: Register for just $75!
Attention life sciences discovery and technology vendors and service providers: Great sponsorship opportunities are available for this important new event!
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SLAS
Gain significant visibility for your research and organization by presenting a poster to academic and industry scientists and technologists from across Europe. The deadline to submit abstracts for poster presentations for the inaugural 2018 SLAS Europe Conference and Exhibition is Friday, May 25. Early registration discounts end May 31.
APPLY TODAY: Students, graduate students, post-doctoral associates and junior faculty (less than four years in first academic appointment) may apply for SLAS Tony B. Academic Travel Awards. Applications are due with poster abstracts on May 25.
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SLAS
Learn more: SLAS SIGs are another way SLAS connects the life sciences community to foster the exchange of information and ideas. Informal, free and organized by SLAS members to explore specialized topics, SLAS SIGs represent diverse interests such as academic drug discovery, ADMET (Absorption, Distribution, Metabolism and Toxicology), drug repurposing, informatics, screen design and assay technology, stem cells and 3D microtissues, women professionals in science and technology and many others! Are you attending the 2018 SLAS Europe Conference and Exhibition? Select SIGs will meet in person at the conference and are open to all attendees.
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Contact us to put our Discovery expertise to work for you, contact: Customerservice@amriglobal.com.
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Science Daily
The CRISPR-Cas9 system has given researchers the power to precisely edit selected genes. Now, researchers have used it to develop a technology that can target any gene in the yeast Saccharomyces cerevisiae and turn it off by deleting single letters from its DNA sequence.
Such genome-scale engineering allows researchers to study the role of each gene individually, as well as in combination with other genes.
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Lab Services PlateDispensers have a new feature. A Temperature Controlled cooling/heating option can now be added. By using a cryostat for high precision thermoregulation, the PlateDispensers TC can maintain a temperature range from 4 to 50 degrees Celsius. A very efficient way to store plates in a thermal environment.
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Journal of the American Chemical Society
Conjugated polymers possessing polar functionalities were shown to effectively anchor single-walled carbon nanotubes (SWNTs) to the surface of high-capacity anode materials and enable the formation of electrical networks. Specifically, poly[3-(potassium-4-butanoate) thiophene] (PPBT) served as a bridge between SWNT networks and various anode materials, including monodispersed Fe3O4 spheres (sFe3O4) and silicon nanoparticles (Si NPs).
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Genetic Engineering & Biotechnology News
Scientists at MIT say they have discovered the factors that determine whether a DNA knot moves along the strand or "jams" in place. The findings could help researchers develop ways to untie DNA knots, which would help improve the accuracy of some genome-sequencing technologies, or to promote knot formation. Inducing knot formation could enhance some types of sequencing by slowing down the DNA molecules' passage through the system, according to the MIT team.
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Bioscience Technology
One of the many mysteries of cancer is the ability of tumor cells to survive and grow in spite of poor blood and nutrient flow.
Led by Flinders Centre for Innovation in Cancer researcher Associate Professor Janni Petersen, scientists in Australia and England have now systematically mapped the core genes and biological processes associated with the ability of cells to survive nutrient stress.
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Chemical & Engineering News
Last August, in a milestone decades in the making, Kymriah became the first cell therapy to be approved by the U.S. Food & Drug Administration. Marketed by the Swiss giant Novartis, Kymriah is made by genetically engineering an individual's own immune cells to attack a form of leukemia.
The approval was based on a groundbreaking clinical study that showed the drug could wipe out the blood cancer in people who had already gone through many unsuccessful rounds of traditional therapy.
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Phys.org
A team of chemists at the University of California San Diego conducted breakthrough research for materials science — a field for which chemistry frequently provides information about the structure and composition of materials, as well as the processes for making and using them. Its aim is to create new materials — from metals and rubber to coatings and crystals.
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Science Translational Medicine
IgA is the most abundant mucosal antibody, and experiments with animal models suggest that it may enforce the gut barrier to prevent dangerous bacteria from damaging the host. However, humans deficient specifically in IgA often have only mild symptoms. Fadlallah et al. examined the fecal microbiomes of healthy individuals in comparison to those deficient in IgA. Overall bacterial diversity was comparable, but different genera were predominant in the patients.
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Lab Manager
The U.S. Department of Energy has approved funding and start of construction for the SuperCDMS SNOLAB experiment, which will begin operations in the early 2020s to hunt for hypothetical dark matter particles called weakly interacting massive particles, or WIMPs. The experiment will be at least 50 times more sensitive than its predecessor, exploring WIMP properties that can't be probed by other experiments and giving researchers a powerful new tool to understand one of the biggest mysteries of modern physics.
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Scientific Director
SLAS
US
Automation and Biochemistry - Research Specialist
Albert Einstein College of Medicine
US – NY – Bronx
Field Support Scientist- Europe
Promega Corporation
UK
Search Jobs at SLAS Career Connections
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