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Does Your Science Fit in a Briefcase? It can if you are following New Matter: Inside the Lives of SLAS Scientists! Our podcast has had more than 300 downloads in the last 30 days and just posted its 25th episode with a chat. Hosted on Buzzsprout, you can find it on a variety of podcast players including iHeartRadio, Apple Podcasts, Spotify, Stitcher, Google Podcasts and more.
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Save the Date for SLAS Transformed: A New Virtual Experience
SLAS
Join researchers and technology providers from around the world on June 23 -24 for a virtual event that will blend virtual science and collaboration to bring you interactive and dynamic sessions on ‘omics, synthetic biology, genome editing and a look at technology used to battle the pandemic. The online event will feature 30-minute scientific research presentations throughout the day, live exhibitor presentations and one-on-one networking including participation incentives for attendees. Details are being added daily. Check the event page often for the latest speaker, programming, exhibit and sponsorship updates. Registration will open soon.
VIEW UP-TO-DATE DETAILS
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Now Available: Part Two of Electronic Laboratory Neighborhood's 'SLAS Community Engages in the COVID-19 Fight'
SLAS
If you enjoyed part one of “SLAS Community Engages in the COVID-19 Fight” you are sure to enjoy part two. Electronic Laboratory Neighborhood feature series takes a closer look at SLAS community members who are using their various scientific backgrounds and leadership roles to step up and help their organizations discover diagnostic breakthroughs in the fight against #COVID19. The latest update includes leaders from Biosero, Hamilton Company, the University of California Berkeley and Medicines Discovery Catapult.
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The coronavirus (COVID-19) is a rapidly evolving threat, and the synthetic DNA that can help discover a vaccine and treatment is needed now — not in eight to ten weeks. SGI-DNA is supporting front-line researchers in combating the spread of COVID-19 by offering $50,000 in co-funding for the BioXp™ 3200 system.
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Present Your Research at the SLAS 2020 Building Biology in 3D Symposium: Schedule at a Glance Available
SLAS
Podium abstracts are being accepted for the 2020 SLAS Building Biology in 3D Symposium (Scripps Research, Jupiter, FL, USA) through Monday, May 25. SLAS invites research scientists, engineers, academics, students and technology providers to submit research and attend to share ideas and insight on:
- enabling technologies,
- high-throughput advanced cellular models,
- advances in imaging and analysis and
- complex translational models.
Save the date for November 17 – 18, 2020. Sponsorship and exhibit opportunities are available. Contact Amanda Schermerhorn for more information.
VIEW CALL FOR ABSTRACT SUBMISSION DETAILS
VIEW SCHEDULE AT A GLANCE
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Hear How NCATS/NIH is Adapting Their Research to Help Fight COVID-19
SLAS
Check out the latest New Matter: Inside the Minds of SLAS Scientists podcast featuring Matt Hall, Biology Group Lead at NCATS/NIH. He and SLAS Scientific Director Mike Tarselli discuss CANVASS, translational medicine, and how NCATS is using screening and assay development to respond to the COVID-19 pandemic.
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Promoted by
Thermo Scientific
The Thermo Scientific™ Orbitor™ RS2 microplate mover is a collaborative bench-top mover that provides unbeatable reliability and improved process efficiency. It’s innovative bi-directional telescoping arm coupled with it’s expansive 360° workspace provide exceptional reach and precision, making the Orbitor RS2 your trusted laboratory productivity partner.
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Calendar of Important Dates
SLAS
SLAS Journal Calls for Papers
High-Throughput Screening, Disease Modeling & Translational Medicine
SLAS Technology
Submission deadline: June 15
Approaches for Prioritizing High-Quality Chemical Matter in Probe and Drug Discovery
SLAS Discovery
Submission deadline: July 1
Applications of Biophysics in Early Drug Discovery
SLAS Discovery
Submission deadline: July 15
Upcoming Events
SLAS is moving forward cautiously and optimistically with our scheduled in-person events, heeding all regional guidelines for group gatherings. We are monitoring all aspects of event[JH1] logistics while developing alternative (virtual) forms of knowledge sharing. SLAS is committed to providing a safe meeting space, high-quality education and meaningful networking opportunities for all attendees, whether in person or on a virtual platform, as circumstances warrant. We look forward to convening in person but will do so only if we can provide a safe and appropriate meeting venue as well as suitable accommodations for travelers.
COMPLETE LIST OF SLAS CONFERENCES AND SYMPOSIA
Save the Date
SLAS 2020 AI Meets Sample Management Symposium – Call for Abstracts Now Open
Boston, MA, USA
November 4 – 5, 2020
SLAS 2020 Building Biology in 3D Symposium – Call for Abstracts Now Open
Scripps Research, Jupiter, FL, USA
November 17 – 18, 2020
SLAS 2021 International Conference and Exhibition
San Diego, CA, USA
January 23 – 27, 2021
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Collaborating to Fight COVID-19
Genetic Engineering & Biotechnology News
The U.S., like many countries around the world, is reeling from the COVID-19 pandemic, causing significant loss of life as well as considerable uncertainty as to how small companies will survive. Fighting the SARS-CoV-2 virus needs a startup company mentality. At my small drug discovery company, each day is an emotional rollercoaster as we grind away, prepared for anything and everything. We are not only hanging on as a company, we are fighting back and pitching into the search for drugs to cure COVID-19.
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How Remdesivir Blocks SARS-CoV-2's Polymerase
Chemical & Engineering News
Researchers have used cryo-electron microscopy to show how remdesivir, an antiviral that’s shown promise against the novel coronavirus, SARS-CoV-2, binds the viral polymerase. Remdesivir is an antiviral designed to act as a prodrug of the nucleotide adenosine. After the drug diffuses into cells, enzymes convert remdesivir to the monophosphate before it disrupts production of new strands of the virus’s RNA. The group purified SARS-CoV-2’s RNA-dependent RNA polymerase and showed in vitro that remdesivir inhibits the enzyme from copying RNA.
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Support for Vaccine Challenge Trials Gains Momentum
The Scientist
In the movie Contagion, a researcher from the Centers for Disease Control and Prevention goes rogue after seeing that a vaccine candidate has worked in a monkey. She injects herself with the formula and then goes to visit her father, who is hospitalized with the fictional virus MEV-1, to expose herself to the pathogen. She doesn’t fall ill, and the success of her risky act accelerates the rollout of a vaccine against the virus.
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Chemistry Breakthrough Could Speed Drug Development
Science Daily
Scientists have successfully developed a new technique to reliably grow crystals of organic soluble molecules from nanoscale droplets, unlocking the potential of accelerated new drug development.
Chemistry experts from Newcastle and Durham universities, working in collaboration with SPT Labtech, have grown the small crystals from nanoscale encapsulated droplets. Their innovative method, involving the use of inert oils to control evaporative solvent loss, has the potential to enhance the drug development pipeline.
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Bacteria 'Factories' Used to Discover Potential New Malaria Drugs
Phys.org
Researchers have engineered bacteria to produce new versions of a potential antibiotic molecule, some with potent antimalarial properties.
Using bacteria to produce new forms of potential drug molecules makes the process faster and cheaper, meaning new drugs could be discovered quicker. The new method, by Imperial College London researchers, is published in Antimicrobial Agents and Chemotherapy. There were 228 million cases of malaria in 2018, and 405,000 deaths.
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Immune Cells Blast Infections and Cancer With Protein 'Bombs'
Science Magazine
Our immune system’s killer T cells earn their name. They destroy infected and cancerous cells, and now, research reveals new details about how they do it. The cells bombard their targets with protein “bombs” packed with deadly chemicals.
The study “is clearly a significant step forward in refining our knowledge” about how these immune sentinels take out dangerous cells, says immunologist David Masopust of the University of Minnesota Medical School.
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Better Antibiotic Dosing Could Save Lives in ICU
Lab Manager
More lives could be saved in intensive care units around the world if new antibiotic guidelines designed by the University of Queensland are adopted.
Researchers have launched universal therapeutic drug monitoring guidelines to optimize the concentrations of antibiotic and antifungal medications given to severely ill patients in hospital.
UQ Centre for Clinical Research professor Jason Roberts said the guidelines could speed up recovery times or even save a critically ill patient from dying.
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Job Seekers: Post your résumé and sign up for new job alerts by keyword.
Employers: Search résumés, post an open position, internship or post-doc opportunity. SLAS Premier and Corporate Members get a discount on all new job postings.
Post-Doctoral Research Position
University of Maryland, Baltimore
US – MD – Baltimore
Scientist I
University of Kentucky
US – KY – Lexington
Two Postdoctoral Fellow Positions
MD Anderson Cancer Center
US – TX – MD Anderson
Search Jobs at SLAS Career Connections
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