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Certified UPS’s to protect your laboratory’s critical instrumentation and resolve current and potential power issues.
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See how the Thermo Scientific Versette automated liquid handler can meet your liquid handling needs!
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The SLAS Innovation Award recognizes the work behind that one unique and special presentation at SLAS2014.
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Interactive e-zine sharing experiences and perspectives on science-related topics. Send article ideas to lvalastyan@slas.org.
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 Foldit Taps Power of Videogames to Solve Complex Protein-Folding Puzzles
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Seth Cooper details the science (and fun!) behind Foldit in the latest SLAS Electronic Laboratory Neighborhood e-zine feature article. "Foldit isn't about knowing a lot of chemistry. It's more about the ability of the players to look at the structures and see how the pieces fit together," Cooper observes. "The game taps into their intuitive 3-D spatial skills—their ability to rotate chains of amino acids in cyberspace."
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SLAS2014 needs YOU!
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The SLAS2014 Scientific Program Committee seeks abstract proposals for podium presentations at SLAS2014, Jan. 18-22, San Diego. Submit your work by Aug. 5 in one of seven tracks. One track, Bioanalytical Techniques, covers quantitative assessments of biological systems from compound activity to cellular phenotype. Possible topics include ADME pharmocokinetics, cytometry, forensics analysis, innovative separations, sample acquisition and preparation, and translation to clinical applications.
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JBS Online features new manuscripts ahead-of-print
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"A Rapid Membrane Potential Assay to Monitor CFTR Function and Inhibition," "A Timetable Organizer for the Planning and Implementation of Screenings in Manual or Semi-Automation Mode" and "High-Throughput Screen for Pharmacoperones of the Vasopressin Type 2 Receptor" are among the new manuscripts available only to SLAS Biomolecular Sciences Section members ahead-of-print.
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Two SLAS Webinars from Effectively Managing Collaborative Science series now available on-demand
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"Lessons Learned in Pharma — CRO Collaboration in Discovery Research" presented by Jonathan Connick of Merck, and "R&D Partnership in Asia and Emerging Markets" led by Ajay Gautam of AstraZeneca are both available on-demand at SLAS.org. The webinars are free to SLAS dues-paid members. The final webinar in the series, "Effectively Managing Collaborative Science" with Liming Shi of Eli Lilly is being held today and will be posted soon.
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The Market Place at SLAS.org — the ultimate online product directory
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The Market Place at SLAS.org offers access to new and existing laboratory science and technology products and services information customized for the SLAS audience. Search by company name, scientific discipline or product category.
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 SLAS CEO speaks at international conference
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Gregory F. Dummer, C.A.E., will share insight on SLAS strategies related to membership development in China at the 2013 Association International Conference. The event is presented by the American Society of Association Executives, which represents more than 21,000 association executives and industry partners worldwide.
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Transport Regulations Impact You.
Saf-T-Pak provides certified shipping systems and compliance training to help ensure public safety in the transportation of Class 6.2 Infectious Substances and related materials. Contact us today! www.Saftpak.com
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Parker Precision Fluidics offers laboratory solutions enabling precise motion and fluidics control for instrument accuracy. RoHS compliant products optimized for stability, long life, and efficiency.
For more information visit www.parker.com/precisionfluidics or email ppfinfo@parker.com.
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Rare disease treatment coming into the limelight
Chemical & Engineering News Share
One afternoon a week, usually on a Tuesday, a nurse arrives at the Elmwood Park, N.J., home of Jeff and Deena Leider to give their sons, Justin and Jason, their "muscle juice." On each visit, she carefully inspects a handful of vials, empties them into an intravenous bag, and calibrates a pump that will slowly dole out the bag's contents. Justin, who at 4 is the younger of the boys, is the first to be hoisted onto the kitchen counter. After taking off his shirt, he sits, swinging his legs and patiently waiting for his superpowers to be activated.
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Researchers develop synthetic HDL cholesterol nanoparticles
Phys.org Share
Atherosclerosis, a buildup of cellular plaque in the arteries, remains one of the leading causes of death globally. While high-density lipoprotein, or HDL, the so-called good cholesterol, is transferred to the liver for processing, low-density lipoprotein, or LDL, builds up in the arteries in the form of plaque. Early detection of cellular components in the plaque that rupture and block arteries have long been held as potentially effective detection for heart diseases and their link to atherosclerosis.
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Bilayer thickness mismatch controls domain size in model membranes
Journal of the American Chemical Society Share
The observation of lateral phase separation in lipid bilayers has received considerable attention, especially in connection to lipid raft phenomena in cells. It is widely accepted that rafts play a central role in cellular processes, notably signal transduction. While micrometer-sized domains are observed with some model membrane mixtures, rafts much smaller than 100 nm — beyond the reach of optical microscopy — are now thought to exist, both in vitro and in vivo.
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Nano-breakthrough: Solving the case of the herringbone crystal
ScienceDaily Share
Leading nanoscientists created beautiful, tiled patterns with flat nanocrystals, but they were left with a mystery: Why did some sets of crystals arrange themselves in an alternating, herringbone style? To find out, they turned to experts in computer simulation at the University of Michigan and the Massachusetts Institute of Technology. The result gives nanotechnology researchers a new tool for controlling how objects one-millionth the size of a grain of sand arrange themselves into useful materials — and a means to discover the rest of the tool chest.
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Get results fast with Hamamatsu’s FDSS µCELL, an imaging-based microplate reader. This affordable, simple-to-use reader accommodates 96- or 384-well microplates for kinetic cell-based assays such as GPCR, ion channel, prolyl isomerase, transporter, and light-activated receptor or channel assays. Click here for more info.
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Sartorius Biohit presents the Picus, the smallest and lightest electronic pipette that eases your workload and provides accurate and precise results. This unique pipette design features patented electronic tip ejection and an intuitive user interface. The Picus has been presented with the 2012 “Red Dot” design award.
Discover Picus at www.sartorius.com/picus.
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Just a 20% increase in lab throughput can save $100,000 in labor costs. The TubePro can help get you there by automatically and precisely labeling tubes. Changeover is quick and easy to accommodate multiple tube sizes. Don’t squander precious staff time on hand labeling. See the video and get up to speed!
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What's missing from many health apps — medical expertise
American Medical News Share
Many smartphone apps on the market offer tips, advice and treatments on how to deal with pain. But many are not backed by science or created with input from a medical professional. This was the finding of a team of researchers from Ohio State University led by Lorraine Wallace, PhD, that analyzed 222 pain-related smartphone apps available for Android, iPhone and Blackberry devices. Of the apps that researchers reviewed, a third had no input from a health care professional.
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Induced pluripotent stem cells: A U.S. patent landscape analysis
Genetic Engineering & Biotechnology News Share
Since their discovery in 2006, induced pluripotent stem cells have promised to revolutionize regenerative medicine and therapies. Similar to embryonic stem cells, iPSCs possess pluripotency but avoid the associated ethical issues. They are re-engineered from various cell types, and several new techniques recently have been developed for their creation. This article reviews the iPSC patent landscape in the United States to the end of identifying the key technologies and institutions that are leading research and development in the creation and use of this promising new technology.
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Finally: Robots learn what 'squishy' really means
IEEE Spectrum Share
Humans use all sorts of bizarre, abstract terms to describe how objects feel, and it's endlessly frustrating to robots. Or at least, we imagine it must be. Take a word like "squishy," for example: how would you explain that feeling to a robot who experiences touch through some long series of numbers? Researchers at University of Pennsylvania's Haptics Group (part of the GRASP Lab) and UC Berkeley have developed a system to teach robots how these abstract terms apply to real-world objects.
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Young blood reverses heart decline in old mice
NewScientist Share
Out with the old, in with the new. Pumping young blood around old bodies — at least in mice — can reverse cardiac hypertrophy — the thickening and swelling of the heart muscle that comes with age and is a major cause of heart failure. Previous studies have shown that an infusion of blood from young mice has rejuvenating effects on the brain of old mice, prompting new cell growth and reversing some of the effects of cognitive decline.
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DropSense96® from Trinean performs high-speed 96well quantification of undiluted bio-samples (2µl). Unique microfluidic sample preservation allows easy robotic integration. Accurate, dye-free quantification by cDrop™ spectral content profiling.
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5 keys to successful research collaborations
By Mike Wokasch Share
 Goals, objectives and circumstances often dictate whether competition or collaboration will produce better results, faster. At the same time, academic groups working in the same disease or therapeutic area would benefit from collaboration rather than competition. Funding is competitive process and, obviously, the rewards for success don't have to be shared. On the other hand, many of these types of research programs are trying to figure out the same thing, answer the same questions and develop the same type of products.
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LRIG Mid Atlantic Chapter meets tomorrow
Laboratory Robotics Interest Group Share
The Laboratory Robotics Interest Group Mid Atlantic Chapter hosts the Nineteenth Annual Technology Exhibition & Presentations Thursday, May 16, from 4-8 p.m. ET in Somerset, N.J.
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Spontaneous gene mutations linked to kids' heart defects
LiveScience Share
Mutations in genes that occur spontaneously may contribute to congenital heart disease in children, according to a new study. These mutations — which arise after conception, rather than being inherited from a parent — may contribute to about 10 percent of cases of congenital heart disease in children, the study said. Congenital heart disease is a group of heart defects (such as holes, or missing parts of the heart), and is the most common type of birth defect in the United States.
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BMG LABTECH is releasing its newest instrument, the CLARIOstar, a high performance microplate reader with advanced monochromators, spectrometer, and filters. With this cutting-edge, hybrid technology, the CLARIOstar offers clear superiority with unparalleled flexibility and sensitivity.
Anything is possible with BMG LABTECH’s CLARIOstar. Any wavelength. Any bandwidth. Any assay.
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IONFIELD SYSTEMS TipCharger™ system uses high-efficiency plasma technology to renew pipette tips. Organic contaminants such as DNA, RNA and compounds are ionized in seconds, allowing disposable tips to be used over and over again! Watch TipCharger Animation Video and see how 30 seconds can save your lab $250,000 per year.
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The comPOUND system comprises a high-density sample storage unit and an additional suite of specialized delivery and processing modules to enable easy integration into any compound management or screening system.
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SLAS Point-to-Point
Colby Horton, Vice President of Publishing, 469.420.2601
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