This message was sent to ##Email##
Advertisement
|
|
|
|
|
|
Advertisement
|
|
|
SLAS
The June 2018 special issue of SLAS Technology provides a meaningful glimpse into the potential and applicability of quantitative imaging as life sciences and biomedical research move into an era of big data and high-content experiments. The issue features a thoughtful editorial and podcast by Guest Editor Anand D. Jeyasekharan, Ph.D., of the Cancer Science Institute of Singapore, National University of Singapore, Centre for Translational Medicine; two review articles and seven original research reports by authors in China, France, Hong Kong, India, Republic of South Korea, Singapore, Spain and the United States.
READ MORE
Advertisement
SLAS
"DNA-Encoded Library Technology (DELT) provides an economical and feasible means to make progress toward the exploration of larger chemical spaces," says Robert Goodnow, Ph.D., vice president of chemistry innovation for Pharmaron (Boston, MA). In a new article from the SLAS Electronic Laboratory Neighborhood (SLAS ELN), Goodnow, guest editor of the June 2018 SLAS Discovery Special Collection, reveals how DELT takes what's been discovered before and builds upon it.
READ MORE
| |
SPONSORED CONTENT | Advertisement
|
|
Promoted by
|
|
|
|
 |
SLAS
Gain valuable exposure and insights for your research by presenting a poster at the inaugural 2018 SLAS Americas Sample Management Symposium: Managing Samples from Bench to Clinic, Nov. 13-14, Boston, MA (USA). Presenting a poster is an effective way for participants to communicate their research to interested colleagues, engage in one-on-one discussion and open doors for future collaboration. The symposium program committee is accepting poster submissions through Monday, Aug. 27. All presenters must be registered as full-conference attendees and be available to present during sessions scheduled for Tuesday, Nov. 13, and Wednesday, Nov. 14.
READ MORE
| |
PRODUCT SHOWCASE | Advertisement
|
 |
|
Because drug discovery involves scientists from multiple disciplines and often organizations, it is critical to have an efficient mechanism for researchers to collaborate and realize the collective value of their specialized knowledge, assets, and capabilities. This free white paper details the essential keys to effective collaboration.
|
|
SLAS
Attention life sciences discovery and technology vendors and service providers: The application deadline for entries into the 2018 SLAS Europe Conference and Exhibition’s New Product Awards is June 25. The product entry must be less than 180 days old in its current form to be considered and launch up to 90 days prior to or 90 days after the event. SLAS2018 New Product Award winners are not eligible.
READ MORE
|
Advertisement
|
|
|
Advertisement
|
|
|
SLAS
SLAS Live Webinar
Thursday, June 7: Register now for "Mitigation and Identification of Aggregation and Nonspecific Reactivity Interference in High-throughput Screening," 11:00 a.m. CT (12:00 p.m. ET, 9:00 a.m. PT).
2018 SLAS Europe Conference and Exhibition
Friday, June 8: Poster abstract submission and Tony B. Academic Travel Award
deadline
Thursday, May 31: Last day to receive discounted registration rates
SLAS2019
Monday, Aug. 6: Deadlines for podium abstracts, SLAS Innovation Award submissions and SLAS Tony B.
Academic Travel Award applications (podium and poster consideration)
Monday, Sept. 24: SLAS Tony B. Academic Travel Award application deadline (poster consideration only)
Monday, Oct. 29: SLAS Student Poster Competition abstracts due
Monday, Jan. 21, 2019: Poster abstract deadline
Advertisement
SLAS
Premier Members can now access the SLAS webinar recording, originally presented by Sridhar Iyengar, Ph.D., on May 8. This well-attended webinar on Using AI and IoT to Accelerate Research expanded on Iyengar's popular presentation at SLAS2018. If you didn't have a chance to view the live webinar, Premier Members can access the recording now by logging in to the SLAS website. Basic Members can upgrade their membership to gain access to the SLAS full on-demand webinar library.
READ MORE
| |
SPONSORED CONTENT | Advertisement
|
|
Promoted by
|
|
|
|
 |
Bioscience Technology
With targeted drug and gene therapies, finding the target cells is only half the battle. Once these agents reach a cell's surface, they still have to get inside and do their job.
University of Illinois researchers say they now know how to track and map drug and gene delivery vehicles to evaluate which are most effective at infiltrating cells and getting to their targets, insight that could guide development of new pharmaceutical agents.
READ MORE
| |
PRODUCT SHOWCASE | Advertisement
|
 |
|
AMRI’s integrated drug discovery centers of excellence combine scientific expertise and leading-edge technology to accelerate innovation. Our complete suite of solutions includes comprehensive discovery biology, synthetic and medicinal chemistry, DMPK and bioanalytical services for successful hit-to-lead-to-candidate selection.
Contact us to put our Discovery expertise to work for you, contact: Customerservice@amriglobal.com.
|
|
Genetic Engineering & Biotechnology News
Scientists in Japan have used CRISPR-Cas9 technology to stop human immunodeficiency virus type 1 replication in latently infected T cells that can't be controlled using existing drug treatments. The gene-editing approach effectively disrupts two regulatory HIV-1 genes, tat and rev, which are essential for viral replication. Describing their in vitro studies in Scientific Reports, the researchers say initial results indicate that using CRISPR-Cas9 to target HIV-1 regulatory genes may offer a new approach to achieving "functional cures."
READ MORE
| |
PRODUCT SHOWCASE | Advertisement
|
 |
|
Due to the different kind of devices used in laboratories, plates have to be loaded into devices with different orientations and/or offsets. Lab Services has developed the PlateCruiser, a sophisticated design for changing plate orientations and re-gripping plates in a time-efficient manner, fully integrated in the PlateButler® Robotic System.
Contact us for more information
|
|
Journal of the American Chemical Society
Chemical tools and methods that report on G protein-coupled receptor expression levels and receptor occupancy by small molecules are highly desirable. We report the development of LEI121 as a photoreactive probe to study the type 2 cannabinoid receptor (CB2R), a promising GPCR to treat tissue injury and inflammatory diseases. LEI121 is the first CB2R-selective bifunctional probe that covalently captures CB2R upon photoactivation.
READ MORE
|
Advertisement
|
|
|
|
|
Science Daily
MIT chemists have devised a way to rapidly synthesize and screen millions of novel proteins that could be used as drugs against Ebola and other viruses.
All proteins produced by living cells are made from the 20 amino acids that are programmed by the genetic code. The MIT team came up with a way to assemble proteins from amino acids not used in nature, including many that are mirror images of natural amino acids.
READ MORE
Chemical & Engineering News
As the first CRISPR clinical trials begin this year in the U.S. and Europe, a number of genome-editing questions remain unanswered. One of the big ones: how to best measure whether a therapy is altering its target gene without introducing errors in others. To address that and other issues in the field, genome-editing companies and U.S. regulators teamed up at a workshop to start working out common standards that will promote better scientific understanding and confidence in therapies.
READ MORE
Phys.org
Scientists have found a new way of joining groups of atoms together into shape-changing molecules — opening up the possibility of a new area of chemistry and the development of countless new drugs, microelectronics and materials with novel characteristics.
Discoveries of new ways to make isomers — molecules made of the same atoms connected together differently — were last reported in 1961 and before then in 1914.
READ MORE
The Scientist
Women given an immune checkpoint inhibitor to treat advanced cancer benefited less from the drugs than men did, according to a meta-analysis of clinical trials involving more than 11,000 patients published in The Lancet Oncology.
"Future research should guarantee greater inclusion of women in trials and focus on improving the effectiveness of immunotherapies in women, perhaps exploring different immunotherapeutic approaches in men and women," the authors write.
READ MORE
Lab Manager
Acute myeloid leukemia is not a single disease. It is a group of leukemias that develop in the bone marrow from progenitors of specialized blood cells, the so-called myeloid cells. Rapidly growing and dividing, these aberrant cells crowd the bone marrow and bloodstream, which can be fatal within weeks or months if the disease is left untreated. Myeloid cells of various types and stages can become cancerous and cause AML, which makes the condition very heterogeneous and difficult to treat.
READ MORE
|
|
Scientific Director
SLAS
US
Chief of the Immunity, Inflammation and Disease Laboratory
National Institute of Environmental Health Sciences/NIH
US – NC – Research Triangle Park
Medical Laboratory Scientist (MLS)
Fairbanks Memorial Hospital
US – AK – Fairbanks
Search Jobs at SLAS Career Connections
| | THANK YOU 2018 SLAS CORPORATE MEMBERS |
|
|
|
7701 Las Colinas Ridge, Ste. 800, Irving, TX 75063
|
