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Brand new episodes of New Matter: Inside the Minds of SLAS Scientists have been uploaded within the last week. Take a deep dive into chemistry machine learning with Ola Engkvist of AstraZeneca Gothenburg (Right Place, Right Time) or listen in as Mike Tarselli discusses DNA storage, miniaturization and the 10-year celebration of SLAS with SLAS2022 Co-Chair Yohann Potier (Bon Anniversaire, SLAS!).
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The coronavirus (COVID-19) is a rapidly evolving threat, and the synthetic DNA that can help discover a vaccine and treatment is needed now — not in eight to ten weeks. SGI-DNA is supporting front-line researchers in combating the spread of COVID-19 by offering $50,000 in co-funding for the BioXp™ 3200 system.
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Iscaffpharma
 Sortina Pharma use Iscaffpharma’s patient derived scaffolds to create drug fingerprints and select drugs for aggressive cancer. Read Case
Reminder: Fall Symposia Abstracts Due Monday, June 15
SLAS
The Call for Abstracts deadline extension for November’s symposia is right around the corner. Do not miss these opportunities to present at the SLAS 2020 AI Meets Sample Management or SLAS 2020 Building Biology in 3D Symposia.
SLAS 2020 AI Meets Sample Management Symposium
November 4 - 5
Boston, MA, USA
Podium abstracts are being accepted in the areas of:
- blockchain,
- target validation,
- the overlap of digital pathology and clinical data automation, and
- off-the-shelf AI.
ABSTRACT SUBMISSION DETAILS
SLAS 2020 Building Biology in 3D Symposium
November 17 - 18
Scripps Research, Jupiter, FL, USA
Podium and poster abstracts are being accepted on the following topics:
- enabling technologies,
- high-throughput advanced cellular models,
- advances in imaging and analysis and
- complex translational models.
VIEW CALL FOR ABSTRACT SUBMISSION DETAILS
VIEW SCHEDULE AT A GLANCE
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Promoted by
Thermo Scientific
The Thermo Scientific™ Orbitor™ RS2 microplate mover is a collaborative bench-top mover that provides unbeatable reliability and improved process efficiency. It’s innovative bi-directional telescoping arm coupled with it’s expansive 360° workspace provide exceptional reach and precision, making the Orbitor RS2 your trusted laboratory productivity partner.
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Festo and SLAS Technology to Host Free Webinar on Wednesday, June 10
SLAS
Join Festo on Wednesday, June 10 at 2 p.m. EDT for the FREE and live webinar, “Best Practice: Optimizing the Design of a Liquid Dispensing System.” Learn more about pressure-based dispensing, the advantages of pneumatic pipetting and the importance of valve control when designing a liquid dispending system. Plus, new technologies and current challenges such as time, pressure and fluid resistance factors will be discussed.
REGISTER NOW
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Evotec’s broad range of sample management capabilities in drug discovery and
 bioanalysis, many years of experience and continued investments in innovation and technology enable us to meet all customers’ needs and deadlines. Find out how the expertise of a global leader in sample management can help your projects.
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Calendar of Important Dates
SLAS
SLAS Events Outlook
SLAS is committed to providing a safe meeting space, high-quality education and meaningful networking opportunities for all attendees, whether in person or on a virtual platform, as circumstances warrant. We look forward to convening in person but will do so only if we can provide a safe and appropriate meeting venue as well as suitable accommodations for travelers. The SLAS team is monitoring all aspects of event logistics and solidifying plans to enable alternative forms of knowledge sharing.
Save the Date
SLAS Transformed — Registration Now Open!
Everywhere
June 23 – 24, 2020
SLAS 2020 AI Meets Sample Management Symposium – Call for Abstracts Deadline Extended to Monday, June 15
Boston, MA, USA
November 4 – 5, 2020
SLAS 2020 Building Biology in 3D Symposium – Call for Abstracts Deadline Extended to Monday, June 15
Scripps Research, Jupiter, FL, USA
November 17 – 18, 2020
SLAS 2021 International Conference and Exhibition — Call for Abstracts Now Open!
San Diego, CA, USA
January 23 – 27, 2021
COMPLETE LIST OF SLAS CONFERENCES AND SYMPOSIA
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Epitaxial Growth of Nanorod Meshes From Luminescent Organic Cocrystals via Crystal Transformation
Journal of the American Chemical Society
Two-dimensional nanorod meshes made of benzoperylene-1,3-dicyanotetrafluorobenzene were formed via crystal transformation of the pre-existing BP microsheets. The transformation was driven by a cooperative effect of intermolecular charge-transfer and arene–perfluoroarene interactions. Epitaxial growth of cyan-emitting BP-1,3-DTFB nanorod meshes was directed by small lattice mismatch between BP and BP-1,3-DTFB, followed by the consumption of BP and the formation of BP-1,3-DTFB. Such a crystal transformation strategy can also be used to guide the formation of BP-1,4-dicyanotetrafluorobenzene nanorod meshes.
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First Human Trial of COVID-19 Vaccines Finds It Is Safe, Induces Rapid Immune Response
Lab Manager
The first COVID-19 vaccine to reach phase 1 clinical trial has been found to be safe, well-tolerated, and able to generate an immune response against SARS-CoV-2 in humans, according to new research published in The Lancet. The open-label trial in 108 healthy adults demonstrates promising results after 28 days — the final results will be evaluated in six months. Further trials are needed to tell whether the immune response it elicits effectively protects against SARS-CoV-2 infection.
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SARS-CoV-2 Spike Protein Shares Sequence With a Human Protein
The Scientist
Scientists determined earlier this year that there is a cleavage site in the SARS-CoV-2 spike protein for furin, a human protease, and that the spike protein is split into two subunits at that spot. This cleavage has been implicated in helping break the virus open so it can enter human cells.
In a paper published in eLife, researchers found that the spike protein’s furin cleavage site is identical to a sequence in the human epithelial sodium channel, which likewise must be cut by furin in order to be activated.
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New Technique Offers Higher Resolution Molecular Imaging and Analysis
Science Daily
A Northwestern University research team has developed a new method to conduct spectroscopic nanoscopy, an approach that could help researchers understand more complicated biomolecular interactions and characterize cells and diseases at the single-molecule level.
The new system, called asymmetrically dispersed spectroscopic single-molecule localization microscopy, builds upon existing sSMLM techniques developed at the McCormick School of Engineering to provide more precise spectroscopic single-molecule analysis to study how cells behind certain cancers, or diseases like diabetic retinopathy, function in their localized environments.
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New Recombineering Method May Overcome Key Obstacle in Genetically Engineering Bacteria
Genetic Engineering & Biotechnology News
Researchers in the Blavatnik Institute at Harvard Medical School and the Biological Research Center in Szeged, Hungary, say they have developed a new genetic engineering technique that promises to transform recombineering methodology.
Their report “Improved bacterial recombineering by parallelized protein discovery” is published in PNAS.
The team created a high-throughput screening technology to look for the most efficient proteins that serve as the engines of recombineering. Such single-stranded DNA-annealing proteins reside within phages.
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Researchers Create Active Material Out of Microscopic Spinning Particles
Phys.org
At the atomic level, a glass of water and a spoonful of crystalline salt couldn't look more different. Water atoms move around freely and randomly, while salt crystals are locked in place in a lattice. But some new materials, recently investigated by researchers at the U.S. Department of Energy's Argonne National Laboratory, show an intriguing propensity to sometimes behave like water and sometimes like salt, giving them interesting transport properties and holding potential promise for applications like mixing and delivery in the pharmaceutical industry.
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Designer Antibodies Fight Cancer by Tethering Immune Cells to Tumor Cells
Science Magazine
Amy Boland has gone through many ups and downs since she noticed lumps under her arms 12 years ago and learned she had cancer of the lymph system. For about six years, conventional chemotherapy helped shrink her lymphoma tumors, but they started to grow again. A succession of other cancer therapies, including a bone marrow transplant and a class of drugs called checkpoint inhibitors, either failed or only brought temporary relief. In one elaborate effort, physicians harvested her T cells, engineered those immune cells to kill her lymphoma, and infused them back into her body.
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Nickel-Loaded Zeolite Snags Small Alkynes From Mixtures With Olefin
Chemical & Engineering News
When making polymers from lower olefins like ethylene, propylene, and 1,3-butadiene, it’s important to ensure no alkynes are in the mix. These small hydrocarbons — acetylene, propyne, and butyne — are by-products of the steam-cracking process that produces lower olefins, but they can poison polymerization catalysts if they’re present in levels above 5 ppm. To eliminate alkynes, polymer makers typically partially hydrogenate them using palladium catalysts. But this method is expensive and can result in fully hydrogenated hydrocarbons.
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Job Seekers: Post your résumé and sign up for new job alerts by keyword.
Employers: Search résumés, post an open position, internship or post-doc opportunity. SLAS Premier and Corporate Members get a discount on all new job postings.
Postdoctoral Research Associate
University of Nebraska Medical Center
US – NE – Omaha
Research Fellow
University of Michigan - Ann Arbor
US – MI – Ann Arbor
Research Technician, Drosophila, Mosquitoes, Viruses, RNAi Boston University School of Medicine
Boston University
US – MA – Boston
Search Jobs at SLAS Career Connections
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The current SLAS Technology Call for Papers deadline on emerging trends in 3D cell culture has been extended to Tuesday, June 30. Invited manuscripts will need to be completed by August 15 for a 2021 publish date. 
Don’t forget these open submission periods for two SLAS Discovery special issues scheduled to publish in 2021. 
