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Certified UPS’s to protect your laboratory’s critical instrumentation and resolve current and potential power issues.
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See how the Thermo Scientific Versette automated liquid handler can meet your liquid handling needs!
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Interactive e-zine sharing experiences and perspectives on science-related topics. Send article ideas to eln@slas.org.
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A collaborative compilation of the world's laboratory technology knowledge grown and updated by an online community.
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 The Lab Man on data standards
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"The call for standards is a lot like someone saying 'there ought to be a law ... ' — easy to say, much harder to make happen." The Lab Man addresses laboratory standards and the individual laboratory scientists and technologists who make them happen in his new blog and podcast.
Also, The Lab Man is now on Twitter! Follow @LabManSLAS to hear from The Lab Man and his sidekick cat Twitty.
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Automation in hemostasis testing: New at JALA Online
SLAS Share
"Technical Evaluation of the Novel Preanalytical Module on Instrumentation Laboratory ACL TOP: Advancing Automation in Hemostasis Testing" is a newly posted manuscript on JALA Online. After extensive testing detailed in the manuscript, collaborating authors from hospitals in Italy and Australia conclude, "the current study provides independent validation of manufacturer claims relevant to important preanalytical components of sample testing, with these being essential to sample integrity. These findings thus provide needed reassurance about the quality of hemostasis test results and subsequently impart additional clinical assurance."
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2013 SLAS Asia Conference and Exhibition attracts 500-plus participants
SLAS Share
More than 500 scientists and related professionals convened June 5-7 in Shanghai, as SLAS hosted its third event in Asia. The event featured 25 scientific presentations and 40 multinational exhibiting companies.
Kudos to Program Committee Co-chairs Bin Li, Ph.D., R&D director, Abbott R&D Center, Shanghai and Shaohui Wang, Ph.D., associate director, Lead Discovery Platform, GlaxoSmithKline R&D China. Event photos can be found on SLAS Facebook.
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Fall SLAS Webinar Series explores phenotypic drug discovery approaches
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The three-part webinar series, "Phenotypic and Signaling Network Approaches as an Alternative to Target Based Drug Discovery," will be offered live this fall and is free for SLAS dues-paid members. Sponsored by Cellular Dynamics International, the webinar schedule is:
Sept. 26
The Value of Phenotypic-Based Drug Discovery
David C. Swinney, Ph.D., Institute for Rare and Neglected Diseases Drug Discovery
Nov. 12
Phenotypic Drug Discovery Using Primary Human Cells and Co-Cultures: Lessons Learned
Ellen Berg, Ph.D., BioSeek, a division of DiscoveRx
Dec. 5
Modern Phenotypic Drug Discovery is a Viable Pharma Strategy
Jonathan Lee, Ph.D., Eli Lilly and Company
Registration is open.
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SLAS2014 short courses announced
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Seventeen one- or two-day deep dives into popular topics of interest to the laboratory science and technology community will be offered Saturday and Sunday, Jan. 18 and 19, preceding SLAS2014 in San Diego. From the tried and true “Introduction to Laboratory Automation” to the new “Introduction to the Derivation and Maintenance of Human Induced Pluripotent Stem Cells,” these courses provide in-depth instruction and are led by practicing professionals.
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Promega funds student scholarships
SLAS Share
Yanling Song and Zhichao Guan from Xiamen University and Xiaoyu Chen, Ming Li and Lijun Wang from Fudan University participated in the 2013 SLAS Asia Conference and Exhibition thanks to scholarships from Promega Corporation. The scholarships included travel reimbursement, hotel accommodations and conference registration. Thank you, Promega!
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Transport Regulations Impact You.
Saf-T-Pak provides certified shipping systems and compliance training to help ensure public safety in the transportation of Class 6.2 Infectious Substances and related materials. Contact us today! www.Saftpak.com
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Parker Precision Fluidics offers laboratory solutions enabling precise motion and fluidics control for instrument accuracy. RoHS compliant products optimized for stability, long life, and efficiency.
For more information visit www.parker.com/precisionfluidics or email ppfinfo@parker.com.
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New class of antibiotics on the horizon
eBioNews Share
A team of researchers has discovered what could become a new and more effective kind of antibiotic that disrupts protein synthesis in bacteria and makes them unable to replicate. With drug-resistant bacterial infections on the rise, it could be a solution to a major health concern around the world. The researchers have found that an early step in the protein synthesis process unique to bacteria is a previously unrecognized drug target.
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'Dark matter' of life: Mysterious bacteria captured
LiveScience Share
The genome of mysterious bacteria that lurk in hospital drains has been sequenced. Low levels of the bacteria, known only as candidate phylum TM6, have been found in water systems around the world, yet because they could not be cultured in the lab, almost nothing was known about them.
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Polymers could help enzymes treat diseases
Phys.org Share
Conditions such as celiac disease, phenylketonuria, lactose intolerance and exocrine pancreatic disease involve abnormal enzyme activity. Enzymes administered orally could help sufferers. However, because enzymes, like all proteins, break down in the stomach and small intestine, they cannot usually survive in the gastrointestinal tract long enough to be effective. However, researchers have found polymers that, when attached to enzymes, will prevent the enzymes from degrading in the GI tract.
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Antibody wakes up T-cells to make cancer vanish
New Scientist Share
Tumors in several people with an advanced form of skin cancer have completely disappeared after treatment with one of three drugs that force tumor cells out of hiding. The patient's own immune system can then recognize the cancer and destroy it. These immunotherapies highlight a promising new strategy in the war against cancer — rebooting the immune system so that it can keep cancers in check whatever tricks they spring on us.
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Get results fast with Hamamatsu’s FDSS µCELL, an imaging-based microplate reader. This affordable, simple-to-use reader accommodates 96- or 384-well microplates for kinetic cell-based assays such as GPCR, ion channel, prolyl isomerase, transporter, and light-activated receptor or channel assays. Click here for more info.
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Sartorius Biohit presents the Picus, the smallest and lightest electronic pipette that eases your workload and provides accurate and precise results. This unique pipette design features patented electronic tip ejection and an intuitive user interface. The Picus has been presented with the 2012 “Red Dot” design award.
Discover Picus at www.sartorius.com/picus.
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Automating your lab but need help at the front-end? Flex TVF (Tube and Vial Feeder) takes bulk tubes—up to 2000 in one hopper load—and quickly orients them in exactly the same position on a belt. Perfect for downstream automation. See it live in action!
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Self-reported substance use versus laboratory assays
By Maria Frisch Share
 Drug testing is commonplace in healthcare, workplace and criminal settings. Urine screens, in particular, have gained widespread use due to ease of sampling. Substance abusers require an accurate diagnosis in order to access the best course of treatment. However, there is still a wide variety of tools to obtain diagnostic status. While some rely on self-report, others rely on lab results, and still others use lab results to confirm self-report. Is one tool better than the other?
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Seeking new tools against Alzheimer's
Genetic Engineering & Biotechnology News Share
With just five successes, all just slowing progression of symptoms for six to 12 months, the road to an Alzheimer's drug has been paved with failure. And the setbacks keep coming, most recently in May, when Baxter International's Gammagard failed in Phase III to reduce cognitive decline or preserve functional ability in mild-to-moderate Alzheimer's patients.
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Researchers, using light to activate neurons, make mice obsessive, or not
MIT Technology Review Share
Two teams of researchers have pinpointed some of the neural circuitry that underlies compulsive grooming behaviors. The discoveries, reported in Science, could guide new treatments for people with obsessive-compulsive disorder, autism, and other conditions that exhibit symptoms of repetitive and compulsive actions.
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A molecule of many colors
Chemical & Engineering News Share
A new, flexible, multi-ring organic compound fluoresces red, green or blue depending on its environment. The molecule's combination of rigid wings and a flexible center could serve as a general design strategy for molecular sensors, the researchers say. The molecule, developed by a team of researchers, has two rigid anthraceneimide wings on opposite sides of a floppy cyclooctatetraene core.
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DropSense96® from Trinean performs high-speed 96well quantification of undiluted bio-samples (2µl). Unique microfluidic sample preservation allows easy robotic integration. Accurate, dye-free quantification by cDrop™ spectral content profiling.
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Making sense of patterns in the Twitterverse
Pacific Northwest National Laboratory Share
If you think keeping up with what's happening via Twitter, Facebook and other social media is like drinking from a fire hose, multiply that by 7 billion — and you'll have a sense of what Court Corley wakes up to every morning. Corley, a data scientist at the Department of Energy's Pacific Northwest National Laboratory, has created a powerful digital system capable of analyzing billions of tweets and other social media messages in just seconds, in an effort to discover patterns and make sense of all the information.
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Second life for possible spintronic materials: Manganese, gallium nitride merged in uniform layer
Science Daily Share
Ten years ago, scientists were convinced that a combination of manganese and gallium nitride could be a key material to create spintronics, the next generation of electronic devices that operate on properties found at the nanoscale. But researchers grew discouraged when experiments indicated that the two materials were as harmonious as oil and water.
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Large-scale aqueous synthesis of fluorescent and biocompatible silicon nanoparticles and their use as highly photostable biological probes
Journal of the American Chemical Society Share
A large-scale synthetic strategy is developed for facile one-pot aqueous synthesis of silicon nanoparticles yielding ∼0.1 g SiNPs of small sizes (∼2.2 nm) in 10 min. The as-prepared SiNPs feature strong fluorescence (photoluminescence quantum yield of 20–25 percent), favorable biocompatibility, and robust photo- and pH-stability. Moreover, the SiNPs are naturally water dispersible, requiring no additional post-treatment.
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BMG LABTECH is releasing its newest instrument, the CLARIOstar, a high performance microplate reader with advanced monochromators, spectrometer, and filters. With this cutting-edge, hybrid technology, the CLARIOstar offers clear superiority with unparalleled flexibility and sensitivity.
Anything is possible with BMG LABTECH’s CLARIOstar. Any wavelength. Any bandwidth. Any assay.
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IONFIELD SYSTEMS TipCharger™ system uses high-efficiency plasma technology to renew pipette tips. Organic contaminants such as DNA, RNA and compounds are ionized in seconds, allowing disposable tips to be used over and over again! Watch TipCharger Animation Video and see how 30 seconds can save your lab $250,000 per year.
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The comPOUND system comprises a high-density sample storage unit and an additional suite of specialized delivery and processing modules to enable easy integration into any compound management or screening system.
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SLAS Point-to-Point
Colby Horton, Vice President of Publishing, 469.420.2601
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