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SLAS ELN Reports: Armin Nourani — Seek the Critique
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The University of Texas at Austin's Armin Nourani was the first-ever undergraduate selected to present from an SLAS conference podium. His work, "Implementation of Nucleic Acid Circuitry in Detection of Melanoma Gene Biomarkers," was featured in the Biomarker Discovery and Applications track at SLAS2015 in Washington, D.C.

Nourani appreciated the opportunity and said, "I learned about so many aspects of science and research [at SLAS2015] that I had never even heard of before, ideas that I could use to improve my research. From that initial interaction, I feel supported already. It is the community that I was hoping for."

Learn more about the industrious Nourani and his passion for diagnostic research in the latest feature article in the SLAS Electronic Laboratory Neighborhood e-zine.
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JBS Editorial Board Member Brings Expertise to South Korean MERS Outbreak
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Hakim Djaballah, CEO of the Institut Pasteur Korea, is on the frontlines of the MERS outbreak in South Korea. "I suspect that the virus has adapted here," he says in the June 2 issue of The Korea Times. "Spread is very unusual and the level of contagion is very high."

The article reported that Djaballah urged Korea's Ministry of Health and Welfare to genetically sequence the virus to learn if it is related to the one found in Saudi Arabia, a recent destination of Korea's first MERS patient.

"It would provide evidence if it is the same species infecting people in Korea or if it has evolved through mutation," he said.

Image credit: NIH National Institute of Allergy and Infectious Diseases.
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Mission to Land on Jupiter's Moon Europa?
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SLAS2016 Keynote Speaker Adam Diedrich Steltzner of NASA's Jet Propulsion Laboratory (JPL) at the California Institute of Technology was part of the JPL team informing U.S. Rep. John Culberson about the possibility of adding a lander to the proposed Europa Multiple Flyby Mission.

Culberson oversees NASA's budget in the U.S. House of Representatives and left the May JPL meeting committed to supporting this effort. Steltzner is SLAS2016 closing speaker on Wednesday, Jan. 27, San Diego.

Image credit: NASA/JPL-Caltech/SETI Institute.
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JBS Open Access: A Cell-Based Internalization and Degradation Assay with an Activatable Fluorescence-Quencher Probe as a Tool for Functional Antibody Screening
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A team from Eli Lilly and Company demonstrates that "the flow cytometric cell-based assay is a powerful and rapid tool for determining the efficiency of internalization and degradation of antibodies bound to targets on the cell surface. Although we have not yet implemented the assay in the discovery process, we have demonstrated that it can be successfully applied to the measurement of antibody internalization and degradation using samples of antibodies in crude supernatants and that, in principle, the assay should be amenable to high-throughput screening." This manuscript is freely available at JBS Online. More



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SLAS Now Accepting SLAS2016 Tony B. Academic Travel Award Applications
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Recipients of Tony B. Awards receive airfare, full conference registration, hotel accommodations and the opportunity to participate fully in SLAS2016, Jan. 23-27 in San Diego, CA.

Students, graduate students, post-doctoral associates and junior faculty may apply for these prestigious travel awards by submitting a podium or poster abstract.

Podium abstracts are due Aug. 3 and poster abstracts can be submitted as late as Sept. 21.
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Job Seekers and Employers Connect via SLAS Career Connections
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Visit this targeted employment exchange regularly to keep up to date with opportunities. Job seekers can post resumes and browse job openings for free. Employers can find new talent by reviewing posted resumes for free and attract new talent by posting job openings for a fee.

Note: SLAS Corporate Members receive a 50 percent discount on job postings.
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3M, Catalent And MannKind Work On Withdrawing The Needle
Chemical & Engineering News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
A single hypodermic needle has been the key apparatus for injecting substances into the bloodstream since 1657. That was when the English architect and scientist Sir Christopher Wren first fashioned a goose quill needle and animal bladder syringe to perform intravenous injections on dogs. Despite decades of research, the syringe and needle continue to be the primary option for ensuring that large-molecule drugs are delivered intact to the blood. More

Chemists Are First to See Elements Transform at Atomic Scale
Phys.org    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Chemists at Tufts University's School of Arts and Sciences, collaborating with PerkinElmer and UCL (University College London), have witnessed atoms of one chemical element morph into another for the first time ever — a feat that produced an unexpected outcome that could lead to a new way to safely treat cancer with radiation. Scientists worked with iodine-125 — a radioactive isotope that is routinely used in cancer therapies. More


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Real-Time Analysis of Cellular Response to Small-Molecule Drugs within a Microfluidic Dielectrophoresis Device
Analytical Chemistry    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Quantitative detection of the biological properties of living cells is essential for a wide range of purposes, from the understanding of cellular characteristics to the development of novel drugs in nanomedicine. Here, we demonstrate that analysis of cell biological properties within a microfluidic dielectrophoresis device enables quantitative detection of cellular biological properties and simultaneously allows large-scale measurement in a noise-robust and probeless manner. More

The Weak Shall Inherit the Petri Dish
Genetic Engineering & Biotechnology News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
In the microbe-eat-microbe world, the weak often prevail against the strong, provided the weak are present in larger numbers, on the order of 99:1. And yet even when the weak qualify as the 99 percent, their occupy movements do not always spread. If they did — if the weak were ever able to declare "winner take all" — they would reduce genetic diversity. In fact, genetic diversity often endures competitive struggles between weak and strong. But how? More



New Type of Drug Can Target All Disease-Causing Proteins
Bioscience Technology    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Current drugs block the actions of only about a quarter of known disease-causing proteins, but Yale University researchers have developed a technology capable of not just inhibiting, but destroying every protein it targets. The new type of drug, called Proteolysis Targeting Chimeras, also can continue to destroy mutant proteins in mouse tumors, according to a new study published in the journal Nature Chemical Biology. More

Adding Precision to the Practice of Medicine
Genetic Engineering & Biotechnology News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
One of the most practical applications of precision medicine lies within the field of pharmacogenomics, a portmanteau of pharmacology and genomics. It is a discipline designed for tailoring drug treatments to an individual's genetic make-up. While scientists have had clinically relevant pharmacogenetic examples of drugs functioning only for patients with specific genetic backgrounds for several decades, the field has burgeoned into the encompassing specialty of pharmacogenomics, shifting away from observing a small number of candidate genes to searching for genome wide biomarkers. More

What's Old Is New Again
The Scientist    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Two researchers sit hunched in front of a fume hood dressed head-to-toe in stark white Tyvek suits, though the yellow-tinted window I'm viewing them through lends the entire scene a sulfurous hue. One of the scientists, a research associate named Hongjie Li, pipettes tiny volumes of solutions containing decades-old DNA into centrifuge tubes, while the other, PhD student Lu Yao, types information into a laptop. Airlock doors and a sensitive ventilation system minimize the incursion of outside air and the myriad bits of contaminating DNA it carries. More

Researchers make ultrasensitive conductivity measurements
Science Daily    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Researchers at Rice University have discovered a new way to make ultrasensitive conductivity measurements at optical frequencies on high-speed nanoscale electronic components. In a series of experiments, researchers from Rice's Laboratory for Nanophotonics linked pairs of puck-shaped metal nanodisks with metallic nanowires and showed how the flow of current at optical frequencies through the nanowires produced "charge transfer plasmons" with unique optical signatures. More

Career


Professor and Chair, Department of Biomathematics
UCLA David Geffen School of Medicine
US – CA – Los Angeles

Vice Chair of Clinical and Translational Informatics
UC Davis School of Medicine
US – CA – Sacramento

Senior Manager Engineering and Validation
Nanotherapeutics
US – FL – Gainesville

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