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  Mobile version   RSS   Subscribe   Unsubscribe   Archive   Media Kit Jun. 20, 2012

SLAS.org    SLAS2013    Moving? New job? Let SLAS know.    


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Screen Your Compounds at Multispan


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Travel Awards Enable SLAS2013 Participation

Students, graduate students, post-doctoral associates and junior faculty may apply for travel awards. Close to 40 awarded last year.



Ten Research-Packed Issues Annually

JBS is the leading peer-reviewed journal focused on drug discovery sciences.


 
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Energy runs high at SLAS Asia Conference and Exhibition
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The 2012 SLAS Asia Conference and Exhibition is underway in Shanghai, where approximately 400 leading international laboratory automation and screening professionals are participating in scientific sessions and exploring new technologies offered by 40 companies. The 2013 Asia Conference and Exhibition will once again be held in Shanghai next June.

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JALA Ten nominations accepted until Sept. 22
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The JALA Ten showcases the top 10 technological breakthroughs of the year that are inspiring the next-generation of medical advances. Nominate a colleague, or yourself, for this prestigious honor by the Sept. 22 deadline. Last year's winners included dissolving microneedles for influenza vaccination and photothermal nanoblades for large cargo delivery into mammalian cells. More

Extra Credit for Students — SLAS Supports Next Generation of Scientists
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For SLAS, support of the next generation of laboratory science and technology professionals is serious business. "We consider how can we reach out to those entering the field — and even those still considering whether they want to enter the field — when planning SLAS programs and services," explains SLAS President Dave Dorsett. Read the new SLAS Electronic Laboratory Neighborhood feature. More



Small automated pipettors perform big
SOLO & SOLOPlus Automated Pipettors are the perfect choice for automating repetitive and time consuming applications. Available in single channel, 8-channel and 12- channel configurations the SOLO handles serial dilutions, kinase assays and next-gen sequencing prep with ease. Multiple deck configurations, accessories and robotics are available. See more at http://www.hudsonrobotics.com/PRODUCTS/Liquid-Handling. Email info@hudsonrobotics.com.


New SLAS2013 short course: 3D Cell-Based Assays for Drug De-Risking
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Industry and academic scientists with mid- to advanced-level experience in cell-based assays or cell biology wishing to get a concise overview about technologies, advantages, cost and application examples of 3-D cell-based assays would be interested in this new short course. It is one of 20 one- or two-day short courses offered at SLAS2013, Jan. 12-16, Orlando, Fla. More

Are you connected fully with SLAS?
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The SLAS presence on the "big three" social media sites continues to grow. Join us on LinkedIn, Facebook and Twitter today! More


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Long-Term Storage (LTS) per Study

Starfruit Software/Database Service - LTS per Study. You can control who to use a sample. Visit Store – Starfruit Library to see "Starfruit Sample Locator BIMS"
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Nexar® HTP, Inline Liquid Handler

Inline liquid handling system for sample and reagent processing in 96- and 384-well Array Tape™. Flexible inline modular options include dispensing, plate storage, incubation and dehydration.
Check it out!


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Small molecule prevents cancer-causing message from entering cell nucleus
Science Daily    Share    Share on FacebookTwitterShare on LinkedinE-mail article
What's good news in one setting might spell disaster in another. In cancer for instance, when a certain cell is commanded to grow and divide without restraint, it's a welcome message for the cell itself but a tragedy for the person who harbors this cell in his or her body. Weizmann Institute scientists have managed to decipher and block one type of molecular message that prompts unbridled cellular growth. More

Binding-induced fluorescence turn-on assay using aptamer-functionalized silver nanocluster DNA probes
Analytical Chemistry    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Presented here is a binding-induced fluorescence turn-on assay for protein detection. Key features of this assay include affinity binding-induced DNA hybridization and fluorescence enhancement of silver nanoclusters (Ag NCs) using guanine-rich DNA sequences. In an example of an assay for human α-thrombin, two aptamers (Apt15 and Apt29) were used and were modified by including additional sequence elements. More

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Rethinking antibody-drug conjugates
Chemical & Engineering News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Not long after Daniel Junius joined ImmunoGen as its head of finance, he came across his employer's name in a lengthy feature in the New York Times. The 2007 story was about "zombie biotechs," and it called out ImmunoGen as one of a handful of companies that for decades lurched along, pursuing a single technology without ever getting a product onto the market. More

Nickel-catalyzed negishi alkylations of styrenyl aziridines
Journal of the American Chemical Society    Share    Share on FacebookTwitterShare on LinkedinE-mail article
A nickel-catalyzed cross-coupling reaction between N-sulfonyl aziridines and organozinc reagents is reported. The catalytic system comprises an inexpensive and air-stable Ni(II) source and dimethyl fumarate as ligand. Regioselective synthesis of β-substituted amines is possible under mild and functional-group-tolerant conditions. More


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New Biohit Roboline™ Liquid-Handling Automate
The Biohit Roboline™ is the ideal companion to automate your routine pipetting work. This small, quiet, and compact liquid handling automate is easy to place anywhere in the lab.

• Precise pipetting, minimizing   human error
• Open programmability
• Saves time and increases   efficiency
• Easy-to-use
• Quiet and compact

Discover Roboline at www.biohit.com/us/roboline
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Investigate major signaling pathways
Cisbio provides a panel of cellular kinase assays dedicated to the measurement of site-specific phosphorylation, in an endogenous cellular environment. These homogeneous assays represent a reliable, robust and rapid alternative to classical technologies like Western Blot, ELISA or bead-based assays.
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Alpaqua Magnet Plates... Like No Other
ALPAQUA® offers 24-well, 96-well & 384-well magnet plates with integrated spring technology for touch-off dispensing and complete supernatant removal while eliminating costly tip crashes and occlusions. Strong NdFeB magnets enable rapid, reliable bead capture and retention. Alpaqua magnet plates are SBS compliant and compatible with many liquid handlers, plate hotels & stackers.


In vitro microvessels for the study of angiogenesis and thrombosis
Preceedings of the National Academy of Sciences    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Microvascular networks support metabolic activity and define microenvironmental conditions within tissues in health and pathology. Recapitulation of functional microvascular structures in vitro could provide a platform for the study of complex vascular phenomena, including angiogenesis and thrombosis. We have engineered living microvascular networks in three-dimensional tissue scaffolds and demonstrated their biofunctionality in vitro. More

Altering the communication networks of multispecies microbial systems using a diverse toolbox of AI-2 analogues
ACS Chemical Biology    Share    Share on FacebookTwitterShare on LinkedinE-mail article
There have been intensive efforts to find small molecule antagonists for bacterial quorum sensing mediated by the "universal" QS autoinducer, AI-2. Previous work has shown that linear and branched acyl analogues of AI-2 can selectively modulate AI-2 signaling in bacteria. Additionally, LsrK-dependent phosphorylated analogues have been implicated as the active inhibitory form against AI-2 signaling. More



Mapping the single cell world
eBioNews    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Researchers map the microbes of the healthy to better understand the sick. A consortium of researchers organized by the National Institutes of Health have mapped the microbial makeup of healthy humans for the first time, revealing a detailed new picture of the single-cell organisms which are crucial elements of digestion, wellness and disease. More

Flu researchers don't know when they can restart work
New Scientist    Share    Share on FacebookTwitterShare on LinkedinE-mail article
After six months of dispute, research in the Netherlands that made a deadly H5N1 flu airborne will be published this week. The scientists behind it now want to get on with their work — but they can't. In December 2011, a U.S. biosecurity committee advised against publishing the research, fearing it was "dual-use research of concern" — done for noble reasons, but dangerous if pathogens escaped or if bioterrorists obtained them. More


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HCS at 40 images/second

In only 8 minutes, TTP Labtech’s acumen eX3 screens:
• Whole wells at 20x
• 96-3456 well plates
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MAP-C2 liquid handling workstation for cell-based assays.

Fully Automated cells dispense, media exchange and cell based assay processing.
Click here for the MAP-C2 video of cell seeding and cell media exchange in Transwell® plates.


Control gene could improve oral vaccines
Drug Discovery & Development    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Scientists have found a master regulator gene needed for the development of M cells, a mysterious type of intestinal cell involved in initiating immune responses. M cells act like "conveyor belts," ingesting bacteria and transporting substances from the gut into Peyer's patches, specialized tissues resembling lymph nodes in the intestines. Better knowledge of M cells' properties could aid research on oral vaccines and inflammatory bowel diseases. More

Oxygen 'sensor' may shut down DNA transcription
Phys.org    Share    Share on FacebookTwitterShare on LinkedinE-mail article
A key component found in an ancient anaerobic microorganism may serve as a sensor to detect potentially fatal oxygen, a University of Arkansas researcher and his colleagues have found. This helps researchers learn more about the function of these components, called iron-sulfur clusters, which occur in different parts of cells in all living creatures. More



iCell® Neurons: Now Two-for-One!
Human iPSC-derived brain cells, iCell® Neurons facilitate drug discovery, neurotoxicity testing, predictive disease modeling, and basic cellular research. They offer a relevant, fully functional human model, exhibiting typical neuronal characteristics and functions. Easy to implement, these cryopreserved neurons are provided in kits with optimized cell culture media.

Buy 1, Get 1 Free during 06/2012


Increasing throughput with automated liquid handling
Genetic Engineering & Biotechnology News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Steady advances in automated liquid handling at the μL to nL level are enabling more scientists around the world to reap the benefits of increased throughput, decreased costs and more efficient use of reagents. Many of the latest techniques were discussed at the recent "European Lab Automation" conference. More

Going 'fat tree'
Lab Manager    Share    Share on FacebookTwitterShare on LinkedinE-mail article
A future weapon in the battle against obesity and diabetes could come in the form of an oil derived from the seeds of wild almond trees, according to researchers at Missouri University of Science and Technology. The key to the oil's potential lies in its ability to affect certain microorganisms living in our bellies. More


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96-Channel Handheld Electronic Pipette
The INTEGRA VIAFLO 96 is a new 96-channel electronic pipette that enables fast, precise and easy simultaneous transfer of 96 samples.
Fast replication or reformatting of 96 and 384 well plates and high precision transferring of reagents, compounds and solutions to or from microplates is now as easy as pipetting with a standard electronic pipette into a single tube.
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Molecular Devices SpectraMax® Limited-Time Promotion
At Molecular Devices, we understand your desire for a top-of-the-line multi-mode microplate reader while balancing an ever-tightening budget. Get the reliability and sensitivity your lab deserves at the price-point you need from a name you trust. Learn more at info.moleculardevices.com
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Get your free automation consultation
Astech Projects launch new turnkey approach to automation at SLAS! Composed of four key steps – consultation & proposal, concept design study, proof of concept, and detailed design, manufacture and testing – Astech currently offers the initial consultation & proposal free of charge. Apply for yours today.


Career


Director, High-Throughput Screening
Southern Research Institute
USA – AL – Birmingham

Postdoctoral Fellow
The Mind Research Network
USA – NM - Albuquerque

Institute Research Scientist – Neurobiology
University of Texas M.D. Anderson Cancer Center
USA – TX – Houston

More jobs at SLAS Career Connections


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