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SLAS Journals' Impact Factors Rise
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SLAS Technology more than doubled to achieve a 2.850 impact factor (up from 1.297) and captured a top 10 position in the Medical Laboratory Technology category. SLAS Discovery moved up to 2.444 (from 2.218). Congratulations to the more than 2,000 volunteer authors and experts who ensure rigorous peer review and high quality for both SLAS official journals.

An impact factor is regarded as a standardized quantitative measure of the relative quality and success of a journal, the research papers it publishes and the authors of the published papers. Impact factors are determined by dividing the number of current citations a journal receives to articles published in the two previous years by the number of articles published in those same years. Citation data is drawn from more than 11,000 of the world's most cited, peer-reviewed journals listed in 236 disciplines and 81 countries.
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From the SLAS President: Fresh Science and Fresh Talent — The SLAS Tony B. Academic Travel Awards
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"With an investment of nearly half a million dollars (from 2010 through 2017), the Tony B. program reflects a serious commitment to the next generation of scientific thought leaders," says SLAS President Scott Atkin. "This investment does much more than cover the cost of airfare and hotel rooms. It is invigorating science, extending collaboration networks and building a stable path forward for our Society."

Atkin indicates 337 students, post-docs and early career professionals have been Tony B. awardees. Podium and poster abstracts and Tony B. applications are now being accepted for SLAS2018, which will be held Feb. 3-7 in San Diego, CA.
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Look Outward: Why the SLAS International Conference and Exhibition is Important
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"By attending and presenting at the SLAS International Conference, scientists can hear about cutting edge developments in science and technology, which seed ideas for future collaborations and projects," says Melanie Leveridge of GlaxoSmithKline and chair of the SLAS2018 Advances in Bioanalytics and Biomarkers Track. "To remain at the cutting edge, it is increasingly important that organizations look outward, and meetings such as SLAS provide the opportunity to learn about the evolving landscape of science and technology, from which to develop future strategic direction."

Read additional reasons and SLAS differentiators offered by your peers, and then submit your work for SLAS2018 podium presentation consideration. Abstracts are due Aug. 7.
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Poster Abstracts Due Aug. 21 for 2017 SLAS Europe HCS Conference
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The 2017 SLAS Europe High-Content Screening (HCS) Conference + Spanish Drug Discovery Network 2017 is Sept. 19-20 in Madrid, Spain. Scientific poster abstract proposals from research scientists, engineers, academics and business leaders are being accepted until Aug. 21.

Conference topics revolve around four topics: data analysis, screening, technology and model systems. Take advantage of this opportunity to interact with a stellar HCS community in Europe.
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Automation and High-Throughput Technologies at SLAS2018
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This SLAS2018 track focuses on the innovative use of biology or chemistry applications, tools, technologies and techniques as they pertain to automated high-throughput screening, the advancement of laboratory processes or improvement of the quality and impact of experimental laboratory data. Emphasis is placed on advancements in chemically and biologically relevant technologies using engineering, analytical, informatics and application to cutting-edge, automation-assisted research. Track chairs are Taosheng Chen of St. Jude Children's Research Hospital and Louis Scampavia of Scripps.

Obtain further information on this track and nine others on the SLAS2018 website. Podium abstract submissions are being accepted until Aug. 7.
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SLAS Europe in Pictures
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Experience recent SLAS Europe events in our Facebook photo galleries!

See participants of the 2017 SLAS Europe Nordic Chemical Biology Meeting, held June 6-7 in Copenhagen. Take a peek at the SLAS Board of Directors, SLAS Europe Council and SLAS professional team looking to the future of the Society during its meetings June 15-16 in Brussels. Your community in action!
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Firefly Gene Illuminates Ability of Optimized CRISPR-Cpf1 to Efficiently Edit Human Genome
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Scientists on the Florida campus of The Scripps Research Institute (TSRI) have improved a state-of-the-art gene-editing technology to advance the system's ability to target, cut and paste genes within human and animal cells — and broadening the ways the CRISPR-Cpf1 editing system may be used to study and fight human diseases. Professor Michael Farzan, co-chair of TSRI's Department of Immunology and Microbiology, and TSRI Research Associate Guocai Zhong improved the efficiency of the CRISPR-Cpf1 gene editing system by incorporating guide RNAs with "multiplexing" capability. More


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Implementation of Activated Ion Electron Transfer Dissociation on a Quadrupole-Orbitrap-Linear Ion Trap Hybrid Mass Spectrometer
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Using concurrent IR photoactivation during electron transfer dissociation (ETD) reactions, i.e., activated ion ETD (AI-ETD), significantly increases dissociation efficiency resulting in improved overall performance. Here we describe the first implementation of AI-ETD on a quadrupole-Orbitrap-quadrupole linear ion trap (QLT) hybrid MS system (Orbitrap Fusion Lumos) and demonstrate the substantial benefits it offers for peptide characterization. More


Diversity-Oriented Stapling Yields Intrinsically Cell-Penetrant Inducers of Autophagy
Journal of the American Chemical Society    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Autophagy is an essential pathway by which cellular and foreign material are degraded and recycled in eukaryotic cells. Induction of autophagy is a promising approach for treating diverse human diseases, including neurodegenerative disorders and infectious diseases. Here, we report the use of a diversity-oriented stapling approach to produce autophagy-inducing peptides that are intrinsically cell-penetrant. These peptides induce autophagy at micromolar concentrations in vitro, have aggregate-clearing activity in a cellular model of Huntington's disease, and induce autophagy in vivo. More




Development of Low-Dimensional Nanomaterials Could Revolutionize Future Technologies
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Javier Vela, scientist at the U.S. Department of Energy's Ames Laboratory, believes improvements in computer processors, TV displays and solar cells will come from scientific advancements in the synthesis of low-dimensional nanomaterials. Ames Laboratory scientists are known for their expertise in the synthesis and manufacturing of materials of different types, according to Vela, who is also an Iowa State University associate professor of chemistry. In many instances, those new materials are made in bulk form, which means micrometers to centimeters in size. More


Scientists Solve 30-Year Old Mystery on How Resistance Genes Spread
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To win the war against antibiotic resistant super bugs, scientists seek to find the origin of resistance genes. Further, they try to identify how the genes are introduced to disease-causing bacteria — so-called pathogens. Identifying where resistance genes come from and how they spread somewhat compares to finding patient zero in an outbreak, which is not an easy task. For more than 30 years, scientists have proposed that resistance genes actually originate from the microorganisms producing the antibiotic. More


New Immune System Finding May Open Door to Novel Cancer Therapies
Genetic Engineering & Biotechnology News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Scientists at the Massachusetts Institute of Technology say they have identified a mechanism that the immune system uses to eliminate genetically imbalanced cells from the body. Almost immediately after gaining or losing chromosomes, cells send out signals that recruit natural killer cells, which destroy the abnormal cells. The findings raise the possibility of harnessing this system to kill cancer cells, which nearly always have too many or too few chromosomes, according to the investigators. More


'Human Project' Study Will Ask 10,000 to Share Life's Data
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Wanted: 10,000 New Yorkers interested in advancing science by sharing a trove of personal information, from cellphone locations and credit-card swipes to blood samples and life-changing events. For 20 years. Researchers are gearing up to start recruiting participants from across the city next year for a study so sweeping it's called "The Human Project." It aims to channel different data streams into a river of insight on health, aging, education and many other aspects of human life. More


US National Institutes of Health Backs Off Funding Limits for Researchers
Chemical & Engineering News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Facing a storm of criticism, the National Institutes of Health has abandoned a plan that would have limited the number of grants any one scientist could get. The Grant Support Index, which NIH rolled out last month, used a formula to determine whether an individual investigator could receive additional NIH funding. NIH leaders said it would effectively limit the number of grants any one scientist could get to three at one time. Complaints quickly came rolling in that the plan would hinder collaboration, work against those running complex trials or research networks, and discourage scientists from overseeing training or infrastructure grants. More


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Research/Sr. Research Fellow
Noven Pharmaceuticals
US – FL – Miami

Sr. Laboratory Automation Engineer
Oxford Immunotec
US – MA – Norwood

Health Technology Research Associate/CRS-02
NYC Department of Health and Mental Hygiene
US – NY – Queens

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