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Certified UPS’s to protect your laboratory’s critical instrumentation and resolve current and potential power issues.
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See how the Thermo Scientific Versette automated liquid handler can meet your liquid handling needs!
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Students, graduate students, post-doctoral associates and junior faculty may apply for travel awards. 45 awarded last year.
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Interactive e-zine sharing experiences and perspectives on science-related topics. Send article ideas to eln@slas.org.
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JALA & JBS impact factors hold strong
SLAS Share
   
The 2012 Thomson Reuters Journal Citation Reports were released last week, announcing new impact factors for scholarly journals. Both the Journal of Laboratory Automation (JALA) and the Journal of Biomolecular Screening (JBS) experienced modest gains with JALA at 1.457 and JBS at 2.207. JALA editor-in-chief is Dean Ho, Ph.D., University of California School of Dentistry, Los Angeles, CA. Robert M. Campbell, Ph.D., Eli Lilly & Company, Indianapolis, IN, is JBS editor-in-chief.
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SLAS supports young scientists
SLAS Share
One way SLAS does its part to ensure the laboratory science and technology professional pipeline remains robust is through its Young Scientist Delegate program, which funds annual conference participation for award-winning young scientists. For SLAS2014, Jan. 18-22 in San Diego, one young scientist delegate will be named at each of the following allied educational events:
Please visit the websites of these organizations for qualification details.
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 SLAS president addresses the social side of science
SLAS Share
SLAS always looks for ways to help members connect with one another, says Jeff Paslay in the new “From the SLAS President” column in the SLAS Electronic Laboratory Neighborhood e-zine. In recent years, our Society’s social media channels on Facebook, LinkedIn, Sina Weibo and Twitter have led to intelligent network building and vigorous information exchange. Paslay invites everyone to join the conversations.
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JALA manuscript details new cell phone-based diagnostic system
SLAS Share
A new JALA report introduces a low-cost, field-deployable diagnostic system for rapid antimicrobial susceptibility testing in resource-limited settings. The system's simplicity, cost-efficiency and effectiveness in detecting bacterial growth make it an ideal telemedicine tool for common tests performed in hospital and field environments. "A Cell Phone-Based Microphotometric System for Rapid Antimicrobial Susceptibility Testing" by Meichei Wang Kadlec, David You, Joseph C. Liao, and Pak Kin Wong is now available to SLAS Laboratory Automation Section members and JALA subscribers at JALA Online.
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SLAS instructions for journal authors now available in Chinese
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Chitthong Tee of Tecan Asia, Singapore and Jianzhong (Jeff) Xi of Peking University, Beijing, China, have translated JALA and JBS manuscript submission instructions into Chinese. SLAS thanks these committed volunteers for their leadership with this important project.
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 SLAS volunteers at the Northern Illinois Food Bank
SLAS Share
The SLAS professional team spent a few hours last week labeling, boxing and palletizing 5,800 pounds of pasta shells at the Northern Illinois Food Bank, a non-profit organization that distributes food to local pantries and provides daily meals to hungry neighbors across 13 counties.
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Transport Regulations Impact You.
Saf-T-Pak provides certified shipping systems and compliance training to help ensure public safety in the transportation of Class 6.2 Infectious Substances and related materials. Contact us today! www.Saftpak.com
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Parker Precision Fluidics offers laboratory solutions enabling precise motion and fluidics control for instrument accuracy. RoHS compliant products optimized for stability, long life, and efficiency.
For more information visit www.parker.com/precisionfluidics or email ppfinfo@parker.com.
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GenomeWeb announces 11th Annual Salary Survey results
GenomeWeb Share
Salaries in the genomics space appear to be hovering at about the same level as they were a year ago, according to respondents to GenomeWeb's annual salary survey. Overall, survey respondents reported making a higher median salary than they did five years ago, though compared to last year's results median salaries in the space appear to be flat.
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DNA origami nanopores for controlling DNA translocation
ACS Nano Share
The authors combined DNA origami structures with glass nanocapillaries to reversibly form hybrid DNA origami nanopores. They say trapping of the DNA origami onto the nanocapillary is proven by imaging fluorescently labeled DNA origami structures and simultaneous ionic current measurements of the trapping events. They then show two applications highlighting the versatility of these DNA origami nanopores.
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Novartis first-generation lung cancer drug tweaked to reduce potential side effects
Chemical & Engineering News Share
Certain lung cancer tumors express an enzyme called anaplastic lymphoma kinase, which is critical to the cancer's survival and spread. As a result, ALK is a popular drug target. Now researchers describe how they redesigned an ALK inhibitor to avoid toxicity issues and produce a promising drug. The new inhibitor, currently in clinical trials to treat non-small-cell lung cancer, is on fast-track review with the Food and Drug Administration.
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Funding cuts forcing young scientists into other careers
Lab Manager Share
Unfortunately, stories of the negative impacts of funding cuts on scientific research are nothing new. However, one consequence not often focused on is how these cuts are forcing talented young scientists into other careers. For example, 29-year-old Tonya Taylor of the University of Minnesota, currently working with one of America's top researchers in degenerative nerve diseases, is considering giving up medical research as a career.
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Get results fast with Hamamatsu’s FDSS µCELL, an imaging-based microplate reader. This affordable, simple-to-use reader accommodates 96- or 384-well microplates for kinetic cell-based assays such as GPCR, ion channel, prolyl isomerase, transporter, and light-activated receptor or channel assays. Click here for more info.
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Sartorius Biohit presents the Picus, the smallest and lightest electronic pipette that eases your workload and provides accurate and precise results. This unique pipette design features patented electronic tip ejection and an intuitive user interface. The Picus has been presented with the 2012 “Red Dot” design award.
Discover Picus at www.sartorius.com/picus.
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Automating your lab but need help at the front-end? Flex TVF (Tube and Vial Feeder) takes bulk tubes—up to 2000 in one hopper load—and quickly orients them in exactly the same position on a belt. Perfect for downstream automation. See it live in action!
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The battle to find a cure for every cancer is evolving
NewScientist Share
Outside the lab, or hospital, we continue to talk about "a cure for cancer" as though it was a single disease, with a single cure. But it's an understatement even to say that every case is different: individual tumors in the same person can be quite different, each carrying enormous numbers of distinct genomes. That may be why cancer is so difficult to treat.
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Leukocyte-mimicking stem cell delivery via in situ coating of cells with a bioactive hyperbranched polyglycerol
Journal of the American Chemical Society Share
Since stem cells emerged as a new generation of medicine, there are increasing efforts to deliver stem cells to a target tissue via intravascular injection. However, the therapeutic stem cells lack the capacity to detect and adhere to the target tissue. Therefore, this study presents synthesis of a bioactive hyperbranched polyglycerol that can noninvasively associate with stem cells and further guide them to target sites, such as inflamed endothelium.
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A detailed 3-D atlas of a human brain
MIT Technology Review Share
A new resource will allow scientists to explore the anatomy of a single brain in three dimensions at far greater detail than before, a possibility its creators hope will guide the quest to map brain activity in humans. The resource, dubbed the BigBrain, was created as part of the European Human Brain Project and is freely available online for scientists to use.
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Psychiatric symptoms following pediatric traumatic brain injury
By Maria Frisch Share
 Will a traumatic brain injury leave a child doomed to a life of depression and anxiety? What are the chances of a child developing a psychiatric disorder as a direct result of TBI? In a recent study, researchers examined this issue. This article highlights the likelihood of psychiatric symptoms in pediatric patients diagnosed with mild to severe TBI.
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Salk scientists discover previously unknown requirement for brain development
eBioNews Share
Scientists at the Salk Institute for Biological Studies have demonstrated that sensory regions in the brain develop in a fundamentally different way than previously thought, a finding that may yield new insights into visual and neural disorders. In a paper published June 7, in Science, Salk researcher Dennis O'Leary and his colleagues have shown that genes alone do not determine how the cerebral cortex grows into separate functional areas.
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A cheaper drive to 'cool' fuels
Science Daily Share
University of Delaware chemist Joel Rosenthal is driven to succeed in the renewable energy arena. Working in his lab in UD's Department of Chemistry and Biochemistry, Rosenthal and doctoral student John DiMeglio have developed an inexpensive catalyst that uses the electricity generated from solar energy to convert carbon dioxide, a major greenhouse gas, into synthetic fuels for powering cars, homes and businesses.
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DropSense96® from Trinean performs high-speed 96well quantification of undiluted bio-samples (2µl). Unique microfluidic sample preservation allows easy robotic integration. Accurate, dye-free quantification by cDrop™ spectral content profiling.
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Creating life-saving drugs from deadly venom
Phys.org Share
When faced with a scorpion, poisonous snake, jellyfish or tarantula, most people would beat a hasty retreat. For a team of scientists investigating the therapeutic potential of their venom, these are however very treasured creatures. The VENOMICS project is extracting their venom, examining its ingredients and testing how each individual molecule could be used by doctors.
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Study: Potential chlamydia link to ovarian cancer
Genetic Engineering & Biotechnology News Share
Chlamydia trachomatis infections can cause mutations in their host DNA by overriding mechanisms through which that host prevents the unregulated growth of genetically damaged cells — a potential cause of ovarian cancer, researchers at the Max Planck Institute for Infection Biology in Berlin have found.
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Development of isotope labeling liquid chromatography-mass spectrometry for metabolic profiling of bacterial cells and its application for bacterial differentiation
Analytical Chemistry Share
Quantitative and comprehensive profiling of cellular metabolites is currently a challenging task in bacterial metabolomics. In this work, a simple and robust method for profiling the amine- and phenol-containing metabolome of bacterial cells is described. The overall workflow consists of methanol-based cell lysis and metabolite extraction with ultrasonication, differential isotope dansylation labeling of cellular metabolites, and analysis of the labeled metabolites by liquid chromatography–mass spectrometry.
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BMG LABTECH is releasing its newest instrument, the CLARIOstar, a high performance microplate reader with advanced monochromators, spectrometer, and filters. With this cutting-edge, hybrid technology, the CLARIOstar offers clear superiority with unparalleled flexibility and sensitivity.
Anything is possible with BMG LABTECH’s CLARIOstar. Any wavelength. Any bandwidth. Any assay.
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IONFIELD SYSTEMS TipCharger™ system uses high-efficiency plasma technology to renew pipette tips. Organic contaminants such as DNA, RNA and compounds are ionized in seconds, allowing disposable tips to be used over and over again! Watch TipCharger Animation Video and see how 30 seconds can save your lab $250,000 per year.
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The comPOUND system comprises a high-density sample storage unit and an additional suite of specialized delivery and processing modules to enable easy integration into any compound management or screening system.
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SLAS Point-to-Point
Colby Horton, Vice President of Publishing, 469.420.2601
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