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  Mobile version   RSS   Subscribe   Unsubscribe   Archive   Media Kit Jul. 3, 2012

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SLAS awards $10,000 cash prize

The SLAS Innovation Award recognizes the work behind that one unique and special presentation at SLAS2013.



Travel Awards Enable SLAS2013 Participation

Students, graduate students, post-doctoral associates and junior faculty may apply for travel awards. Close to 40 awarded last year.


 
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SLAS ELN: Mobile technology charts new directions
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Mobile technology is beginning to transform not only the way companies manage their compound screening and profiling systems, but the entire healthcare landscape from drug discovery to patient care. Turning familiar devices such as cell phones and video game consoles into platforms for data collection and point-of-care analysis, these advances promise to improve disease detection and diagnosis, as well as healthcare delivery. A new SLAS Electronic Laboratory Neighborhood feature explores the challenges and opportunities for innovation. More

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2012 SLAS Asia Conference registrant wins SLAS2013 prize package!
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Xiaotao Wang, senior scientist, AstraZeneca, Shanghai, is the winner of an SLAS2013 prize package, including roundtrip airfare to/from Orlando, Fla., USA, up to four nights hotel accommodations and a full conference registration. Wang's name was pulled randomly from all 2012 SLAS Asia Conference and Exhibition full conference paid participants. More

Aug. 31 deadline: 2013 JALA & JBS Art of Science Contest
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Creating great images is just one more way scientists share information resulting from their great work. Will your visual take first place in the 2013 JALA & JBS Art of Science Contest and win The New iPad? Fall just short and win one of 10 honorable mention $50 Amazon gift cards? You won't know unless you enter the contest. More



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New LabAutopedia Book of the Month
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Mark Bowden tells the story of the experts who united to combat the Conficker worm, first detected late in 2008, which infected millions of computers including government, business and home computers. Bowden is the bestselling author of Black Hawk Down: A Story of Modern War, as well as The Best Game Ever, Bringing the Heat, Killing Pablo and Guests of the Ayatollah. He reported at The Philadelphia Inquirer for 20 years and now writes for Vanity Fair, The Atlantic and other magazines. More

New manuscripts posted at JBS Online
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"Cell-Permeable, Small-Molecule Activators of the Insulin-Degrading Enzyme" and "Development of a Profiling Strategy for Metabolic Mixtures by Combining Chromatography and Mass Spectrometry with Cell-Based GPCR Signaling" are among the new manuscripts available only to SLAS Biomolecular Sciences Section members ahead of print. More


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Quick, without checking the website first, which of these speakers is NOT keynoting SLAS2013, Jan. 12-16, Orlando?
  • Mehmet Toner
  • Justin Bieber
  • Sir Harold Kroto
  • Charles Sabine
Click here to give SLAS your answer.


news


Scientists develop alternative to gene therapy
Science Daily    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Scientists at The Scripps Research Institute have discovered a surprisingly simple and safe method to disrupt specific genes within cells. The scientists highlighted the medical potential of the new technique by demonstrating its use as a safer alternative to an experimental gene therapy against HIV infection. The new technique employs zinc finger nuclease proteins, which can bind and cut DNA at precisely defined locations in the genome. More

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Stem cells used to create Huntington's model
Drug Discovery & Development    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Scientists at the Gladstone Institutes and an international team of researchers have generated a human model of Huntington disease — directly from the skin cells of patients with the disease. For years, scientists have studied Huntington's disease primarily in post-mortem brain tissue or laboratory animals modified to mimic the disease. More

Combining crystallography and visible spectroscopy to understand enzymes
Phys.org    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The research team focused on the stachydrine demethylase from Sinorhizobium meliloti 1021. The applications of electronic absorption and resonance Raman spectroscopies, in conjunction with x-ray diffraction, all derive from the same ~25 µm2 region of the crystal (intersection of the cross hairs). The x-ray beam alters the visible spectrum of the crystal with each exposure required to determine the crystal structure of the trimeric enzyme and the Fe-S cluster within each subunit. More


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Discover Picus at www.sartorius.com/picus.
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Investigate major signaling pathways
Cisbio provides a panel of cellular kinase assays dedicated to the measurement of site-specific phosphorylation, in an endogenous cellular environment. These homogeneous assays represent a reliable, robust and rapid alternative to classical technologies like Western Blot, ELISA or bead-based assays.
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In vitro selection of highly modified cyclic peptides that act as tight binding inhibitors
Journal of the American Chemical Society    Share    Share on FacebookTwitterShare on LinkedinE-mail article
There is a great demand for the discovery of new therapeutic molecules that combine the high specificity and affinity of biologic drugs with the bioavailability and lower cost of small molecules. Small, natural-product-like peptides hold great promise in bridging this gap; however, access to libraries of these compounds has been a limitation. More

Anticancer prospect made from scratch
Chemical & Engineering News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The natural product (+)-Fusarisetin A, which has promising anticancer properties and an unusually complex structure, has succumbed to total synthesis. (+)-Fusarisetin A has intrigued drug designers because experiments show that it inhibits migration and metastasis of cancer cells, seemingly without exhibiting cell-killing proclivities that might point to toxic tendencies. More



Study suggests somatic transposon insertion may help spur development of some cancers
Genome Web    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Retrotransposon movement in somatic cells may introduce insertions in the genome that contribute to tumorigenesis in certain cancer types, according to a study in the early, online edition of Science by members of the Cancer Genome Atlas Research Network and their collaborators. More

Programmable RNA complex could speed genome editing in the lab
eBioNews    Share    Share on FacebookTwitterShare on LinkedinE-mail article
For bacteria, snipping apart DNA that bears certain signature sequences is a defense mechanism. For scientists working in the lab, the same strategy can be a powerful research tool. With a newly discovered component of an adaptive bacterial immune system, scientists have identified a targeted method of slicing DNA that they say can be easily customized for a variety of applications in the lab. More


Effortless high content imaging

TTP Labtech’s acumen eX3 can analyse over 40 images/second – allowing you to profile compound libraries in hours. Don’t sacrifice throughput for high content. MORE
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Safety without sacrifice
Bioscience Technology    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Whether identified as Repetitive Stress Disorder, Repetitive Stress Injury or Cumulative Trauma Disorders, musculoskeletal injuries in the workplace have been a serious issue for the past decade, amounting to tens of billions of dollars in costs associated with diagnosis and treatment. In a recent news release summarizing 2009 statistics, the U.S. Department of Labor, Bureau of Labor Statistics reported over 348,740 cases of ergonomically related injuries. More

Proteins: Disordered with a purpose
Live Science    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Like guards who control entry and exit from a building, specialized molecules like the ion channel pictured with this article regulate which ions pass through a cell's membrane. Researchers have recently discovered that this channel has a special "messy" region that is important in its function. More



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Structure-based design of novel inhibitors of the MDM2-p53 interaction
Journal of Medicinal Chemistry    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Structure-based rational design led to the discovery of novel inhibitors of the MDM2–p53 protein–protein interaction. The affinity of these compounds for MDM2 was improved through conformational control of both the piperidinone ring and the appended N-alkyl substituent. Optimization afforded 29 (AM-8553), a potent and selective MDM2 inhibitor with excellent pharmacokinetic properties and in vivo efficacy. More

Giant living power cables let bacteria respire
New Scientist    Share    Share on FacebookTwitterShare on LinkedinE-mail article
It is the ultimate in subsea communications: bacteria living in sulphurous mud beneath the seabed respire by transforming themselves into long, insulating cables and shuttling electrons from one to another. This phenomenon has now been imaged for the first time, allowing us to see how some microbes pull off such a feat. More

App connects rare disease researchers to data
Genetic Engineering & Biotechnology News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Investigators of rare and neglected diseases can access some of the latest research in the field, plus data about the disorders themselves, through a recently launched free app for Apple devices. Sean Ekins, Ph.D., D.Sc., a consultant on computational drug discovery research, and Alex M. Clark, Ph.D., a designer of software for drug discovery scientists, have created Open Drug Discovery Teams. More


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Get your free automation consultation
Astech Projects launch new turnkey approach to automation at SLAS! Composed of four key steps – consultation & proposal, concept design study, proof of concept, and detailed design, manufacture and testing – Astech currently offers the initial consultation & proposal free of charge. Apply for yours today.


Career


HTP DNA Sequencing and Genotyping Scientist I
St. Jude Children's Research Hospital
USA – TN – Memphis

Staff Engineer – Laboratory
The New York Stem Cell Foundation
USA – NY – New York

Specialist Biomed Engineering
North Shore-LIJ Health System
USA – NY – Manhasset

More jobs at SLAS Career Connections


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