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SLAS ELN Reports: First SLAS Graduate Education Fellowship Grant Fuels HTS Droplet Array Concept
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Meet the first SLAS Graduate Education Fellowship Grant recipient: Erik M. Werner, a graduate student and Ph.D. candidate from the University of California, Irvine. Werner is a keen collaborator who wants practical, yet complicated, science — such as microfluidics — to be more user-friendly.

Werner is an engaging mentor who helps high school students find the joy of discovery; and a tireless innovator whose pursuits in high-throughput screening will benefit from the $100,000 SLAS grant. Read more about Werner in the SLAS Electronic Laboratory Neighborhood e-zine.
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Students, Post Docs and Junior Faculty: SLAS Can Help You Attend SLAS2017
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The SLAS Tony B. Academic Travel Award is one way SLAS ensures that up-and-coming researchers who demonstrate outstanding achievement have the opportunity to learn from and interact with life sciences discovery and technology community leaders. If selected for a Tony B. Award, travel, hotel accommodations and conference registration are provided to the primary author of a submitted podium or poster abstract for SLAS2017, Feb. 4-8, Washington, DC. For podium presentations, abstracts and applications are due Aug. 8; for poster presentations, Sept. 26 is the deadline.

Pictured here are three of the 60 Tony B. Award winners from SLAS2016 — Joohun Kang (Wyss Institute, Harvard University), Carrie Lovitt (Griffith University Australia) and Masturah Bte Mohd Abdul Rashid (National University of Singapore).
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JBS Call for Abstracts: Special Issue on Advances in MALDI Mass Spectrometry for Drug Discovery
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Guest editors Shannon Cornett, Ph.D., of Bruker and Michael Scholle, M.S., M.B.A. of SAMDI Tech invite your manuscript proposals (abstracts) by Sept. 30 for this 2017 special issue. Proposals will be used to select papers for submission and peer review.

Areas of interest include high-throughput MALDI applications; use of MALDI in enzyme characterization; applications of MALDI and MALDI imaging for metabolite detection and screening and for drug distribution studies; matrix-free or laser desorption Ionization applications and techniques; and novel approaches of MALDI to study biological systems and biochemical characterization.
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SLAS Europe High-Content Screening Conference Draws 160 Participants
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This June 27-29 conference in Dresden, Germany, gathered HCS researchers, academics and industry professionals to explore the latest advances and emerging technologies in the field. Hot topics included novel organisms, novel markers, new essays, novel microscopy techniques, image analysis and statistics.

It was held at the Max Planck Institute of Molecular Cell Biology and Genetics, and the SLAS Scientific Committee included Marc Bickle of MPI; Thierry Dorval of Servier in France; and Maria Montoya of Centro Nacional de Investigaciones Cardiovasculares (CNIC) in Spain. According to the committee, attendees had high praise for the quality of the presentations and networking and are looking forward to a next edition in 2017.
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Take the Quiz! Which Reagent Are You?
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Just as each reagent reacts to a system in a distinct way, different scientists can affect the same project in a unique fashion. Take a short, just-for-fun quiz to determine which reagent best represents your personality. Then share your "true colors" with your peers via Facebook and Twitter!

Also, consider presenting your life sciences discovery and technology research at SLAS2017. Among the many benefits of presenting, you will be part of an elite group of industry experts and can further your research with input from well-qualified peers. The SLAS2017 podium abstract submission deadline is Monday, Aug. 8.
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New and FREE at JBS: Identification of Novel Inhibitors of the Type I Interferon Induction Pathway Using Cell-Based High-Throughput Screening
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A collaborative team from Scotland's University of St Andrews and University of Dundee has developed and executed a cell-based high-throughput screen (HTS) targeting components that participate in and/or regulate the IRF3 and nuclear factor (NF)–κB branches of the IFN induction pathway.

The assay detects activation of the IFN induction pathway via an enhanced green fluorescent protein (eGFP) reporter gene under the control of the IFNβ promoter and is optimized, miniaturized, and demonstrates suitability for HTS as robust Z' factor scores of >0.6 are consistently achieved. This is a SAGE Choice article, allowing all readers immediate free access to the full manuscript.
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New Model Predicts Once-Mysterious Chemical Reactions
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A team of researchers from Los Alamos National Laboratory and Curtin University in Australia developed a theoretical model to forecast the fundamental chemical reactions involving molecular hydrogen, which after many decades and attempts by scientists had remained largely unpredicted and unsolved. More


Sustainable Chemistry Students Solve Decades-Old Oxidation Puzzle
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Students at the University of Amsterdam have designed a new catalyst that can render important chemical processes more sustainable. Their catalyst can create selective peroxide-like reagents literally from thin air and uses those to oxidize alcohols to carbonyl compounds in a dual-action mechanism. The results have just been published online by Chemistry: A European Journal. More


Stem Cell Finding May Improve Understanding of Metastatic Cancers
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Researchers at North Carolina State University have discovered that therapeutic stem cells exit the bloodstream in a different manner than was previously thought. This process, called angiopellosis by the researchers, has implications for improving our understanding of not only intravenous stem cell therapies, but also metastatic cancers. More


Photonic Lab-on-a-Chip: Integration of Optical Spectroscopy in Microfluidic Systems
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The integration of micro-optical elements with microfluidics leads to the highly promising photonic lab-on-a-chip analytical systems (PhLoCs). In this work, we re-examine the main principles which are underneath the on-chip spectrophotometric detection, approaching the PhLoC concept to a nonexpert audience. More


Scientists Study Compounds With Anti-Prion Properties to Address Rare But Fatal Diseases
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A team of scientists from the University of Alberta is examining compounds with anti-prion properties, which can alter the misfolding of proteins in rare but universally fatal prion diseases like Mad Cow and Creutzfeld-Jakob. Their results have just been published in Nature Communications. "The goal of our work is to figure out how to address protein misfolding diseases," says Michael Woodside, professor in the Department of Physics, cross-appointed at the National Institute for Nanotechnology. More


Tackling CO Poisoning With Single-Atom Alloy Catalysts
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Platinum catalysts are extensively used in the chemical industry and as electrocatalysts in fuel cells. Pt is notorious for its sensitivity to poisoning by strong CO adsorption. Here we demonstrate that the single-atom alloy (SAA) strategy applied to Pt reduces the binding strength of CO while maintaining catalytic performance. More


Tiny Peptide Targets Brain Injuries
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Researchers have found a four-amino-acid peptide that selectively binds to sites of injury in the brain. Such a peptide could help guide small molecules, proteins, and nanoparticles designed to detect or treat traumatic brain injury, the scientists say. Currently, there are no good treatments to limit the long-term damage caused by traumatic brain injuries experienced by accident victims or military personnel. More


Researchers Identify Calorie-burning Pathway in Fat Cells
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Investigators at Dana-Farber Cancer Institute, in collaboration with scientists at the University of California, Berkeley, have identified a natural molecular pathway that enables cells to burn off calories as heat rather than store them as fat. This raises the possibility of a new approach to treating and preventing obesity, diabetes and other obesity-linked metabolic disorders, including cancer. More


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The Klein Endowed Chair in Alzheimer's Disease and Neurodegeneration Research
Rutgers Brain Health Institute
US – NJ – Piscataway

Automation Specialist, Proteomics
Broad Institute of MIT and Harvard
US – MA – Cambridge

Senior QC Microbiologist II
Astellas
US – CA – Santa Monica

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