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Certified UPS’s to protect your laboratory’s critical instrumentation and resolve current and potential power issues.
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Discussions and musings focused on the engaging field of laboratory science and technology.
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The SLAS Market Place offers access to new and existing technology products and services for your laboratory.
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JALA and JBS 2011 impact factors announced
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"We are proud that our journals are performing so well," says SLAS CEO Greg Dummer. "Their success in the Journal Citation Reports is validation of their high quality. These ratings reinforce what our members consistently tell us — that both JALA and JBS are valuable and important to the laboratory science and technology community." The JALA impact factor is 1.420; JBS is 2.049. This is JALA's first reported impact factor.
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Charles Sabine says Huntington's disease research is making great strides
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SLAS2013 keynote speaker Charles Sabine says he's "never witnessed such genuine excitement among researchers in this field than at this conference," speaking from the 2012 Huntington Society of Canada event. The video includes a conversation with JALA Scientific Advisor Leroy Hood, M.D., Ph.D., Institute for Systems Biology, and other top researchers. CHDI Foundation, a biomedical research organization exclusively dedicated to rapidly discovering and developing therapies that slow the progression of Huntington's disease, created the video.
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Submit SLAS2013 podium abstracts by end of month
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Monday, July 30, is the deadline for SLAS2013 podium abstract submissions and the chance to compete for the $10,000 SLAS Innovation Award. Selected presenters have the opportunity to showcase their scientific work before a global audience of leaders in the laboratory science and technology community. SLAS2013 educational tracks are Assay Development and Screening; Bioanalytical Techniques; Diagnostics; Drug Target Biology; High-Throughput Technologies; Informatics; and Micro/Nano Technologies.
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SLAS2013 Tony B. Academic Travel Awards deadline is July 30
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For just two more weeks, students, graduate students, post-doctoral associates and junior faculty can submit podium abstracts and opt in to be considered for a Tony B. Academic Travel Award. The awards, which include airfare, SLAS2013 registration and shared hotel accommodations for selected students, honor Association for Laboratory Automation Co-Founder Tony Beugelsdijk of Los Alamos National Laboratory, who passed away in August 2009. SLAS2013 will be held Jan. 12-16 in Orlando, Fla.
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More photos posted to Facebook
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Additional photos from the 2012 SLAS Asia Conference and Exhibition were posted to the SLAS Facebook page this week. The three-part photo gallery documents the highly successful event, which welcomed 470 participants from 14 countries, June 19-21 in Shanghai, China.
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The Nexar® system provides inline sample storage, liquid handling, incubation, and detection. High throughput, miniaturized reaction volumes and walk-away operation. Check it out!
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In human and ortholog GPCR stable cell lines in Calcium, cAMP, IP-1, GTPγS, ligand-binding and internalization assays, offering the fastest turnaround, highest quality and most diversity. More>> Email: info@multispaninc.com
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Association for Molecular Pathology sets Annual Meeting
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The AMP 2012 Annual Meeting on Genomic Medicine is Oct. 25-27 in Long Beach, Calif. Early registration ends Aug. 20 for this meeting. AMP is committed to clinical molecular diagnostic and prognostic medicine through education and training of practitioners, physicians, laboratory and industrial scientists, and healthcare professionals involved in patient care and management.
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'Fingerprinting' nanoscale objects and viruses
Science Daily Share
  
Scientists at UB and IBEC in Barcelona have found a way of effectively identifying nanoscale objects and viruses that could offer a breakthrough for biomedical diagnostics, environmental protection and nano-electronics. Scientists have made amazing progress in the last two decades in seeing and manipulating materials at the nanoscale. New generation microscopes enable researchers to explore the morphology of nanoscale objects in their natural environment.
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Moisturizer modified to tackle skin cancer
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When a disease runs skin deep, perhaps all that is needed is moisturizer supercharged with gene-regulation technology. For skin conditions including melanoma, treatments that are applied directly to the skin are the ideal drug solution: they are easy to use and they affect only the area under which they are applied. The problem is that our skin is such a successful barrier against toxins that finding substances that penetrate it is a huge challenge.
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Freeze drying 101: Back to basics training course
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SP Scientific is offering a new four-part, free online training course for scientists to build a basic understanding of the theory and concepts behind freeze drying — an essential pre-requisite for those looking to design a working lyophilization process. Led by Jeff Schwegman, the course will run every Wednesday between July 11 and Aug. 1.
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SRU Biosystems has introduced the first and only high resolution, optical, label-free plate reader. Capable of measuring functional responses in individual cells, the SCANNER represents a new paradigm in drug discovery enabling the use of primary cells earlier in drug discovery process. Contact us to learn more.
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Get results fast with Hamamatsu’s FDSS µCELL, an imaging-based microplate reader. This affordable, simple-to-use reader accommodates 96- or 384-well microplates for kinetic cell-based assays such as GPCR, ion channel, prolyl isomerase, transporter, and light-activated receptor or channel assays. Click here for more info.
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At Molecular Devices, we understand your desire for a top-of-the-line multi-mode microplate reader while balancing an ever-tightening budget. Get the reliability and sensitivity your lab deserves at the price-point you need from a name you trust. Learn more at info.moleculardevices.com
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Hello, Higgs Boson: LHC's new particle looks like the real thing
Popular Science Share
  
"We have discovered a new particle," CERN director general Rolf Heuer said. "A boson. Most probably a Higgs boson." Even the most anticipated news in science does not come without some caveats. Still, all signs point to a discovery that is arguably one of the most important findings in modern physics. The inscrutable Higgs boson, carrier of mass and final puzzle piece of physics' prevailing theory, may have finally been found.
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New biological signaling agent identified
Chemical & Engineering News Share
  
Thionitrous acid, HSNO, may be a key molecule in biological signaling and regulation, linking the effects of nitric oxide and hydrogen sulfide, according to a research report. The findings may be important for a better understanding of the way cardiac and nerve signals are regulated. Some effects of nitric oxide are familiar: Nitroglycerin, for example, releases nitric oxide to open blood vessels to alleviate heart pain.
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New insights into how the most iconic reaction in organic chemistry really works
Phys.org Share
  
In 1928, chemists Otto Diels and Kurt Alder first documented diene synthesis, a chemical reaction important for synthesizing many polymers, alkaloids and steroids. Their work on this mechanism, which came to be known as the Diels–Alder reaction, won them the 1950 Nobel Prize in chemistry. Since then, the iconic reaction has become the most commonly used and studied mechanism in organic chemistry. But what happens during the reaction has never been entirely clear.
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Polyatomic anion assistance in the assembly of [2]pseudorotaxanes
Journal of the American Chemical Society Share
  
We describe the use of polyatomic anions for the quantitative assembly of ion-paired complexes displaying pseudorotaxane topology. Our approach exploits the unique ion-pair recognition properties exhibited by noncovalent neutral receptors assembled through hydrogen-bonding interactions between a bis-calix[4]pyrrole macrocycle and linear bis-amidepyridyl-N-oxides.
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TTP Labtech’s acumen eX3 can analyse over 40 images/second – allowing you to profile compound libraries in hours. Don’t sacrifice throughput for high content. MORE
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Modular automation for tube and vial feeding, labeling, and racking including 600 dpi printer resolution, 'whisper' feed automatic feeders, and robotic racking systems. MORE
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Transcription factor Lyl-1 critical in producing early T-cell progenitors
eBioNews Share
  
A transcription factor called Lyl-1 is necessary for production of the earliest cells that can become T-cells, critical cells born in the thymus that coordinate the immune response to cancer or infections, said a consortium of researchers led by those from Baylor College of Medicine in a report in the journal Nature Immunology. These earliest progenitors are the first cells that can be identified as being on the road to becoming T-cells.
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Surface roughness directed self-assembly of patchy particles into colloidal micelles
Proceedings of the National Academy of Sciences Share
  
Colloidal particles with site-specific directional interactions, so called "patchy particles," are promising candidates for bottom-up assembly routes toward complex structures with rationally designed properties. Here we present an experimental realization of patchy colloidal particles based on material independent depletion interaction and surface roughness. Curved, smooth patches on rough colloids are shown to be exclusively attractive due to their different overlap volumes.
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Scientists identify protein required to regrow injured nerves in limbs
Lab Manager Share
  
A protein required to regrow injured peripheral nerves has been identified by researchers at Washington University School of Medicine in St. Louis. The finding, in mice, has implications for improving recovery after nerve injury in the extremities. It also opens new avenues of investigation toward triggering nerve regeneration in the central nervous system, notorious for its inability to heal.
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Bees do it: Brain aging reversed
Live Science Share
  
When older honeybees take on tasks usually handled by younger bees, aging of their brains is effectively reversed, a new study finds. The discovery suggests that in humans, social intervention ought to be considered in addition to drugs as a way to treat age-related dementia. "We knew from previous research that when bees stay in the nest and take care of larvae — the bee babies — they remain mentally competent for as long as we observe them," explained Gro Amdam, who led the research.
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VIAFILL™ from INTEGRA delivers high performance bulk reagent dispensing, multichannel pipetting and microplate washing capabilities all from a single multipurpose instrument. A choice of different tubing sets allow quick changing between these three operational modes making VIAFILL a uniquely versatile lab tool. MORE
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Are you interested in outsourcing your cell/ biochemical assay development, compound screening or equipment validation to experienced pharma scientists?
We are a pre-clinical CRO specialising in bespoke bioassay development, plate-based compound pharmacology and instrument/reagent validation.
Learn more at www.aureliabio.com
Contact us at enquiry@aureliabio.com
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ALPAQUA® offers 24-well, 96-well & 384-well magnet plates with integrated spring technology for touch-off dispensing and complete supernatant removal while eliminating costly tip crashes and occlusions. Strong NdFeB magnets enable rapid, reliable bead capture and retention. Alpaqua magnet plates are SBS compliant and compatible with many liquid handlers, plate hotels & stackers.
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