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Text version   RSS   Subscribe   Unsubscribe   Archive   Media Kit July 20, 2016

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Travel Awards Enable SLAS2017 Participation

Students, graduate students, post-doctoral associates and junior faculty may apply for travel awards. 60 awarded for SLAS2016.


 




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From the SLAS President: Introducing SLAS Discovery and SLAS Technology
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In 2017, SLAS's two scientific journals will begin their 22nd year of publication with new names and taglines! The Journal of Biomolecular Screening (JBS) will become SLAS DiscoveryTM (Advancing Life Sciences R&D); and the Journal of Laboratory Automation (JALA) will become SLAS TechnologyTM (Translating Life Sciences Innovation).

While our journal names are changing, their trusted commitment to innovation is not changing. SLAS Discovery and SLAS Technology's editorial rigor, integrity, aims and scope will remain solidly and dependably in place. SLAS Discovery will continue to focus on advancing life sciences R&D, publishing reports of how scientists develop and utilize novel technologies and/or approaches to provide and characterize chemical and biological tools to understand and treat human disease. SLAS Technology will continue to focus on translating life sciences innovation, publishing ways in which scientists adapt advancements in technology for scientific exploration and experimentation. The new names simply are more accurate reflections of what has been and is being published in them.
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19 Days Remain! SLAS2017 Podium Abstracts Due Aug. 8
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Are you leveraging the power of new technologies to achieve scientific objectives? SLAS members want to know the details. Submit a scientific presentation abstract by Aug. 8 for the opportunity to showcase your research on the global stage of SLAS2017, Feb. 4-8, Washington, DC.

Detailed information on seven scientific tracks, including overall descriptions, session titles and track and session chairs is now online. The SLAS2017 Scientific Program Committee is looking for innovation, relevance and applicability. While you’re at it, take our short and fun quiz to find out what reagent color best suits your scientific personality.
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New and FREE at JBS: Virtual Screening of DrugBank Reveals Two Drugs as New BCRP Inhibitors
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A collaborative team from the Department of Pharmaceutical Chemistry at the University of Vienna (Austria) built a ligand-based in silico classification model to predict the inhibitory potential of drugs toward the breast cancer-resistant protein (BCRP). The early identification of substrates and inhibitors of this efflux transporter can help to prevent or foresee drug-drug interactions.

The model is applied as a virtual screening technique; 10 compounds are selected and tested for their capacity to inhibit mitoxantrone efflux in BCRP-expressing PLB985 cells, and results identify cisapride (IC50 = 0.4 µM) and roflumilast (IC50 = 0.9 µM) as two new BCRP inhibitors. This is a SAGE Choice article, allowing all readers immediate free access to the full manuscript.
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SLAS2017 Special Session: Whose Responsibility is Research Reproducibility?
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There is a broad consensus among academic and industry researchers, funders and other stakeholders that increasing reproducibility of published research is an important goal. However, questions of who should be responsible for validating research results are tricky; industry and academia naturally diverge in answering these.

SLAS2017 is forming a panel of experts representing both industry and academia to address this challenging and often contentious issue. Lenny Teytelman of Protocols chairs this session as well as the SLAS2017 Data Analysis and Informatics Track.
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Grow Your Network: Volunteer with SLAS
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At SLAS, volunteering and opportunity go together like discovery and technology.

"SLAS is an avenue for collaboration, partnerships and opportunity," says Hansjoerg Haas of Thermo Fisher Scientific.

Complete the online form to indicate your volunteer interests and areas of expertise. Then, accept a role when contacted and grow your professional network like never before!
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Scientists Delve into 'Black Box' of DNA Research
Bioscience Technology    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Scientists at Florida State University, Baylor College of Medicine and the Broad Institute of Harvard and MIT have broken ground in a little-understood area of human genetics. In a new study published in the Proceedings of the National Academy of Sciences, researchers show that an unusual DNA repeat element on an inactive X chromosome is actually essential to the overall three-dimensional structure of this female-specific genetic phenomenon. More


Big Data's Role in Drug Discovery
Lab Manager    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Projecting over the next decade, scientists at the University of Illinois, Urbana-Champaign, suggested in a commentary published in the journal PLOS Biology in 2015 that these data could end up swamping all currently available storage, based on the expected 100 million to 2 billion human genomes that could be sequenced by 2025. And their estimate didn't take into account transcriptome, epigenome, or proteome data, let alone the massive storage requirements of medical images. More


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Real-Time, Selective Detection of Copper(II) Using Ionophore-Grafted Carbon-Fiber Microelectrodes
Analytical Chemistry    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Rapid, selective detection of metals in complex samples remains an elusive goal that could provide critical analytical information for biological and environmental sciences and industrial waste management. Fast-scan cyclic voltammetry using carbon-fiber microelectrodes is an emerging technique for metal analysis with broad potential applicability because of its rapid response to changes in analyte concentration and minimal disturbance to the analysis medium. More


Considering Gene Editing
The Scientist    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Shortly after 8 a.m. on July 12, more than two dozen people filled the small conference room at the National Academies' Keck Center as the Committee on Human Gene Editing convened for the fourth time since it was assembled last year. The committee's task: to research, discuss, and report on "the scientific underpinnings of human gene-editing technologies, their potential use in biomedical research and medicine — including human germline editing — and the clinical, ethical, legal, and social implications of their use." More




Viruses Are a Primary Driver of Human Evolution
Genetic Engineering & Biotechnology News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Scientists have always known of the impact that viral pathogens have had on Homo sapiens evolution. Remnants of viral DNA can found dispersed throughout the human genome, but until recently scientists have not had the tools to look at how the influence of viruses has spread globally across species and genomes. Now, a new study by researchers at Stanford University applies big-data analysis to reveal the full extent of viruses' impact on the evolution of humans and other mammals. More


Replication of Enzyme-Nucleotide Chimeras
Phys.org    Share    Share on FacebookTwitterShare on LinkedinE-mail article
DNA polymerases are the "Xerox machines" that replicate our DNA. They must work with great precision to keep errors from creeping into our genes. In spite of this precision, they still accept building blocks that have been coupled to large proteins, as a group of German scientists reports in the journal Angewandte Chemie. Based on this fact, the team has developed detection systems for genotyping DNA and RNA that can be evaluated by the naked eye. This method may allow for new diagnostic tools for use in the field. More


Scientists Make Single-Atom Memory From Copper and Chlorine
Science Magazine    Share    Share on FacebookTwitterShare on LinkedinE-mail article
In 1960, U.S. physicist Richard Feynman famously predicted the coming age of nanotechnology in an essay entitled "There's Plenty of Room at the Bottom." Nowhere has this idea proven more powerful than in the realm of data storage, where by continually shrinking the size of bits of data, today's computer hard disk drives now pack 10,000 times more information than those from just 15 years ago. Now, that march to the bottom may finally be nearing its end. More


How Slack-ing Helps Chemists Manage Their Labs
Chemical & Engineering News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Founders of Silicon Valley start-ups dream about building fast-growing companies and workforces. It's not something chemistry professors such as Anne J. McNeil usually think about for their labs, though. McNeil had been leading a group of chemists developing new gels and polymers at the University of Michigan for seven years, when, in 2014, she won a Howard Hughes Medical Institute professorship. More


Career


Automation Engineer, Next Generation Sequencing
Roche Diagnostics
US – MA – Boston

The Klein Endowed Chair in Alzheimer's Disease and Neurodegeneration Research
Rutgers Brain Health Institute
US – NJ – Piscataway

Field Automation Scientist, Next Generation Sequencing
Roche
United States (Virtual Work Location)

Search Jobs at SLAS Career Connections


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