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SLAS
Technologies that are reducing costs and changing the ways in which researchers and clinicians process and use therapeutic cells are showcased in the August 2018 special issue of SLAS Technology. With leadership from guest editor Christopher Puleo, Ph.D., and colleagues of General Electric Global Research (Niskayuna, NY, USA), the issue presents two review articles that detail the status of cell bioreactors in both stem cell and tissue/organ engineering applications and five original research reports by life sciences researchers from universities, pharma companies and hospitals in Australia and across the United States. Image Credit: Coleman Murray, University of California, Los Angeles.
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SLAS
A new August 2018 special issue of SLAS Discovery on high-throughput flow cytometry (HTFC) in drug discovery captures recent advances that inform us about the current state of automated workflows, the expanding range of applications and the creativity in some novel assays. The issue is timely as "HTFC is gaining acceptance and people are using it in innovative ways," says Co-Guest Editor Bruce Edwards, Ph.D., of the University of New Mexico (UNM, Albuquerque, NM, USA) in a new article in SLAS Electronic Laboratory Neighborhood (SLAS ELN). SLAS Discovery Editorial Board member and Co-Guest Editor Mei Ding, Ph.D., of AstraZeneca (Gothenburg, Sweden) and Edwards teamed up last fall for the special issue.
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SLAS
Register now: secure your registration discount at the 2018 SLAS Advanced 3D Human Models and High-Content Analysis Conference, Oct. 17-19, Leiden, The Netherlands. Save up to €80 when you register before Sept. 7! Be a part of progress by participating in interactive roundtable discussions on future developments to transition from organoids to mini organs.
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SLAS
Attention assay and screening scientists: Get cutting-edge information on technologies and methodologies to advance chemical matter for clinically relevant pharmacologies. Drug Target Strategies, one of 10 educational tracks to be offered at SLAS2019, will focus on inducing protein degradation, multidimensional approaches to determining mechanism-of-action (MOA) and applying genomic and proteomic technologies to drug target validation and MOA studies. Submit your novel research in this area: Podium abstracts for consideration are due Monday, Aug. 6.
Students: Apply for an SLAS Tony B. Academic Travel Award when you submit your podium or poster abstract. The travel award application and podium abstract deadline is Monday, Aug. 6. The deadline for travel awards for poster abstract submissions is Monday, Sept. 24. Submit your work to be considered for the SLAS Student Poster Competition by Monday, Oct. 29.
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SLAS
Discover new products and services to improve efficiency and productivity in your lab. Explore SLAS's premier online product directory and buyer's guide for life sciences discovery and technology. Searchable by category, keyword or postal code, the SLAS MarketPlace at SLAS.org puts contact information of retailers and resellers, product demo videos and much more at your fingertips. Browse categories covering everything from automated systems and components to informatics and computing, from instrumentation and hardware, to labware, lab supplies and microplates. The Services section offers quick connections to business and engineering consultants, CROs, re-sellers and distributors. READ MORE
Vendors: Consider featuring your product or service in the SLAS MarketPlace at SLAS.org!
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AMRI’s integrated drug discovery centers of excellence combine scientific expertise and leading-edge technology to accelerate innovation. Our complete suite of solutions includes comprehensive discovery biology, synthetic and medicinal chemistry, DMPK and bioanalytical services for successful hit-to-lead-to-candidate selection.
Contact us to put our Discovery expertise to work for you, contact: Customerservice@amriglobal.com.
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SLAS
2018 SLAS Advanced 3D Human Models and High-Content Analysis Conference
Friday, September 7: Deadline for registration discount
Thursday, Oct. 4: Poster abstract deadline
SLAS Europe: Call for Volunteers
Tuesday, July 31: Deadline for applications to the SLAS Europe Scientific Program Committee (Europe SPC), SLAS Advocacy Committee, Strategic Alliances Committee and Awards and Grants Committee
SLAS2019
Monday, Aug. 6: Deadlines for podium abstracts, SLAS Innovation Award submissions and SLAS Tony B. Academic Travel Award applications (podium and poster consideration)
Monday, Sept. 24: SLAS Tony B. Academic Travel Award application deadline (poster consideration only)
Monday, Oct. 29: SLAS Student Poster Competition abstracts due
2018 SLAS Americas Sample Management Symposium: Managing Samples from Bench to Clinic
Monday, Aug. 27: Deadline for poster abstracts
Monday, Oct. 1: Deadline for registration discount
Tuesday, Oct. 16: Secure discounted hotel rates at the Omni Parker House (rooms are going fast)
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Analytical Chemistry
Microfluidic devices provide ideal environments to study solvent extraction. When droplets form and generate plug flow down the microfluidic channel, the device acts as a microreactor in which the kinetics of chemical reactions and interfacial transfer can be examined. Here, we present a methodology that combines chemometric analysis with online micro-Raman spectroscopy to monitor biphasic extractions within a microfluidic device.
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Genetic Engineering & Biotechnology News
Gene editing using the CRISPR-Cas system has exploded with therapeutic potential over the last several years, and while researchers have begun to exploit the bacterial defense system to treat an array of diseases, little is known about the molecular battle between CRISPRs and invading viruses. A better understanding of these molecular events could enable therapeutic intervention using phage viruses.
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Lab Manager
For over a century, scientists have studied E. coli, one of the bacteria that cause food poisoning, as a model for fighting infections. Such research has led to a variety of antibiotics that penetrate the protective cell walls of bacteria to kill them.
Now, a multi-university study led by Stanford bioengineer KC Huang reveals that E. coli has managed to keep a big secret about its defenses.
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Chemical & Engineering News
When nanoparticles are used for drug delivery, they often end up in the liver or spleen instead of the intended target. A team led by Jacob S. Brenner and Vladimir Muzykantov of the University of Pennsylvania now shows that nanocarrier delivery can be improved by having the nanocarriers "hitchhike" on red blood cells. The researchers withdrew red blood cells from mice and incubated them with nanoparticles, which absorbed on the cell surface.
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Phys.org
A new type of artificial-intelligence-driven chemistry could revolutionize the way molecules are discovered, scientists claim.
In a new paper published in the journal Nature, chemists from the University of Glasgow discuss how they have trained an artificially-intelligent organic chemical synthesis robot to automatically explore a very large number of chemical reactions.
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Laboratory Equipment
Researchers at Oregon State University have used deep learning to decipher what ribonucleic acids have the potential to encode proteins.
The gated recurrent neural network developed in the College of Science and College of Engineering is an important step toward better understanding RNA, one of life's fundamental, essential molecules.
Unlocking the mysteries of RNA means knowing its connections to human health and disease.
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Science Daily
In the quest to realize artificial photosynthesis to convert sunlight, water, and carbon dioxide into fuel — just as plants do — researchers need to not only identify materials to efficiently perform photoelectrochemical water splitting, but also to understand why a certain material may or may not work. Now scientists have pioneered a technique that uses nanoscale imaging to understand how local, nanoscale properties can affect a material's macroscopic performance.
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Job Seekers: Post your résumé and sign up for new job alerts by keyword.
Employers: Search résumés, post an open position, internship, or post-doc opportunity. SLAS Premier Members get a discount on all new job postings.
Clinical Trials Associate I
Vanderbilt Health
US – TN – Nashville
Quality Assurance Auditor
The Emmes Corporation
US – MD – Rockville
Principal Scientist, Biotherapeutic Assay Development and High-Throughput Screening
Pfizer
US – MA – Cambridge
Search Jobs at SLAS Career Connections
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