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The Scientist consults SLAS Screening Stem Cells 2011 experts
SLAS Share
   
"iPS cells allow scientists to strip a disease down to the 'pure essence of what a genetic background is doing to alter function,'" said Chad Cowan, in The Scientist, July 20. Cowan, SLAS Screening Stem Cells 2011 session chair, along with symposium keynoters Kevin Eggan and Rudolph Jaenisch, explain why "induced pluripotent stem cells are
biology's hottest new tool for understanding disease."
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JALA: New discovery on total internal reflection fluorescence microscopy
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Authors Ning Fang, Wei Sun, Aoshuang Xu, Kyle Marchuk and Gufeng Wang detail how a new microscope system combines the variable-angle TIRFM and variable-illumination-depth pseudo TIRFM to image the whole cells from the basolateral membrane to the apical membrane. Learn about it in the August issue of JALA.
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Get results fast with Hamamatsu’s FDSS µCELL, an imaging-based microplate reader. This affordable, simple-to-use reader accommodates 96- or 384-well microplates for kinetic cell-based assays such as GPCR, ion channel, prolyl isomerase, transporter, and light-activated receptor or channel assays. Click here for more info.
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Ion channels regulate the excitability of cells
SLAS Share
Claire Townsend, Ph.D., GlaxoSmithKline kicks off the all-new, three-part SLAS virtual course on Sept. 8 with an introduction to the diverse
family of ion channels. She hopes that a better understanding of their function will mean true progress toward a wide variety of therapeutic areas. Register today!
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Collaborate, innovate, dominate — register early for SLAS2012
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Take the laboratory science and technology field by storm at SLAS2012, Feb. 4-8 in San Diego. Education. Exploration. Discovery. Be part of the scientific savvy, technical innovation and energy that will be SLAS 2012. Register NOW to take advantage of the deepest discounts on registration and travel.
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The
Access™ laboratory workstation transforms any Echo® liquid handler into an automated system for gene expression assays with reaction volumes as low as 250 nL. MORE |
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New LabAutopedia Book of the Month: Pharmaceutical Profiling
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Edited by SLAS enthusiasts, Pharmaceutical Profiling in Drug Discovery for Lead Selection focuses on how to increase the efficiency of drug discovery and development. The book is featured in the SLAS Electronic Laboratory Neighborhood.
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SRU Biosystems has introduced the first and only high resolution, optical, label-free plate reader. Capable of measuring functional responses in individual cells, the SCANNER represents a new paradigm in drug discovery enabling the use of primary cells earlier in drug discovery process. Contact us to learn more.
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Ultra Low Attachment Surface plates feature a covalently bound hydrogel layer that effectively inhibits cellular attachment, minimizes protein absorption, enzyme activation, and cellular activation. Corning® introduces 384 well black clear bottom Ultra Low Attachment Surface plates for HTS
applications of tumor spheroid and stem cell embryoid body screening.
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Douglas Scientific’s Array Tape™ is a flexible microplate replacement for high throughput applications. It’s a continuous polymer strip, embossed with reaction
wells in customized volumes and formats including 384-well arrays. Miniaturized well sizes of 1 µL allow smaller reactions and reduce reagent costs. Request a free sample today!
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Researchers identify seventh and
eighth bases of DNA
eBioNews Share
For decades, scientists have known that DNA consists of four basic units — adenine,
guanine, thymine and cytosine. In recent years, scientists have expanded that list from four to six. Now, with a finding published online in the July 21 issue of the journal Science, researchers from the UNC School of Medicine have discovered the seventh and eighth bases of DNA.
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Chemical producers show good profits
Chemical & Engineering News Share
In the U.S. and Europe, the economic recovery has been slow and fragile. But economists would be hard-pressed to find clues to the world's economic problems by looking at the data
contained in C&EN's survey of the Global Top 50 chemical companies. The statistics, based on 2010 company results, show that the chemical industry has made a strong recovery from 2009. In fact, the industry is performing better than it has in more than a decade.
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Bristol-Myers buys pharmaceuticals company
eBioNews Share
Bristol-Myers Squibb Company and Amira Pharmaceuticals, Inc., announced that the companies have signed a definitive agreement under which Bristol-Myers Squibb will acquire privately held Amira Pharmaceuticals, a small-molecule pharmaceutical company focused on the discovery and early development of new drugs to treat inflammatory and fibrotic diseases.
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Researchers design self-assembling material that can house other molecules
Science Daily Share
Chemical reactions happen all the time: some things burn or rust, others react to light exposure — even batteries use chemical reactions to supply electricity. One of the big challenges chemists continually face is finding new ways to control these reactions or create conditions that promote desirable reactions and limit undesirable ones.
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Nature Lab Offers provides researchers like you with exclusive discounts from top suppliers of lab products. Register at nature.com/laboffers for
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Scientists find new components for protein transport
PhysOrg Share
Research scientists at the Ruhr University Bochum discovered a new enzyme, which gives decisive insights into protein import into specific cellular organelles (peroxisomes). In the Journal of Biological Chemistry, the team of Prof. Erdmann reports that the enzyme Ubp15p collaborates with two other proteins to convert the protein transport machinery back into its initial condition after work has been
completed.
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Archimedean molecule creates brand new compounds
New Scientist Share
There are only 13 "Archimidean solids" — a family of symmetrical, 3D polyhedra attributed to the Greek mathematician. Now chemists have made a molecule-scale version of one of these special structures, known as the truncated octahedron. The tiny, hollow structure acts as a cage, capable of encapsulating a surprising variety of ions and molecules without falling apart. It also aids the creation of substances
that won't otherwise form.
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The 10 most ambitious experiments in the universe today
Popular Science Share
These 10 awe-inspiring science projects range from the world's largest undersea observatory to the "ultimate microscope" to a Jupiter orbiter on a suicide mission — but they're all massive, often in both size and scope.
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Report offers new framework to guide K-12 science education
National Academy of Sciences Share
A report released by the National Research Council presents a new framework for K-12 science education that identifies the key scientific ideas and practices all students should learn by the end of high school. The framework will serve as the foundation for new K-12 science education standards, to replace those issued more than a decade ago.
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The Sci-Print VX2 automates the mundane task of hand-labeling tubes and vials. User-friendly software interfaces with LIMS or worklists to generate label information. The system can label microtubes, vials and vacutainers ranging from 0.5mL up to 50mL. The Sci-Print VX2 prints human readable text
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The HTFC® Screening System from IntelliCyt is a fast, highly sensitive, and simple-to-operate multicolor platform for phenotypic screening. This automation-friendly system can
analyze thousands of cells per second from 96 or 384 well microplates and create heatmap data displays to quickly visualize hits.
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Discussions and musings focused on the engaging field of laboratory science and technology.
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JBS is the leading peer-reviewed journal focused on drug discovery sciences.
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