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Act Now: SLAS2016 Podium Abstracts Due Aug. 3
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Submit a scientific abstract by this Monday, Aug. 3, for an opportunity to showcase your compelling research and new perspectives on emerging laboratory technologies on a prestigious global stage next January in San Diego, CA. SLAS2016 will feature a world-class scientific program centered around high profile life sciences R&D podium presentations from pioneering researchers from around the world.
The Aug. 3 podium abstract deadline also is in place for students applying for a Tony B. Academic Travel Award, which provides airfare, full conference registration, hotel accommodations and the opportunity to participate fully in SLAS2016.
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JALA Special Issue on New Developments in Biosensing Technologies
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"Biosensing is a very broad research field that calls for continued development within both scientific and industrial arenas," says JALA Guest Editor Xianting Ding, Ph.D., Shanghai Jiao Tong University, China. "Advancement in technologies will enrich the application of biosensing devices and platforms in disease diagnosis, biological investigation, environmental monitoring, food engineering, and drug discovery."
SLAS Laboratory Automation Section members and JALA subscribers can read the issue now at JALA Online.
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Judging Criteria for SLAS $1 Million Graduate Education Fellowship Grant Program to be Announced Soon
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The members of the recently launched SLAS Grant Review Panel met last week in Chicago to establish selection criteria for this new Society scholarship program.
SLAS will award a two-year scholarship (up to $50,000 per year) annually to a student conducting research related to quantitative biosciences and/or life sciences. Watch SLAS.org for details and the opening of the online application process.
Panel members, pictured left to right, are Josh Bittker, Tyler Aldredge, Chair Sue Lunte and Frank Fan. Not pictured: Krister Wennerberg.
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The SLAS Electronic Laboratory Neighborhood E-Zine: Thought-Provoking and Practical
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"The SLAS Electronic Laboratory Neighborhood e-zine is the only place where I read about how other life sciences R&D professionals evolved into their roles, overcame challenges, suffered setbacks and achieved greatness in their quests to cure cancer, turn back time or otherwise contribute to mankind's greater good," says SLAS President Dean Ho in his latest From the SLAS President column in the SLAS e-zine.
"Although the specifics of our puzzles may be different, much of our critical thinking and many of our creative solutions can apply to our parallel universes. This e-zine illustrates the energetic and talented bench depth of our scientific community by painting individual portraits of our members at work and in life."
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JBS August Issue Available Online
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Two open access manuscripts are among the original research papers included in the August issue of JBS: "A Cell-Based Internalization and Degradation Assay with an Activatable Fluorescence–Quencher Probe as a Tool for Functional Antibody Screening" from Eli Lilly and Company and "Phenotypic Approaches to Identify Inhibitors of B Cell Activation" from Janssen Research and Development.
SLAS Biomolecular Sciences Section members and JBS subscribers can read the full issue at JBS Online now.
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SLAS Seeks Candidates for Europe Council
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Individuals who wish to serve on the SLAS Europe Council are invited to submit materials for consideration by midnight, CET, Friday, Aug. 21. Nominations must include a short statement of your reasons for seeking election and an affidavit acknowledging your eligibility to serve.
The SLAS Europe Nominating Committee will select a minimum of four candidates, and all full dues-paying members of SLAS in Europe will be invited to vote in the final election. The two candidates who earn the most votes will serve as Council members for three-year terms beginning January 2016.
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UCLA Researchers Create Smartphone-Based Device That Reads Medical Diagnostic Tests Quickly and Accurately
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Enzyme-linked immunosorbant assay, or ELISA, is a diagnostic tool that identifies antigens such as viruses and bacteria in blood samples. ELISA can detect a number of diseases, including HIV, West Nile virus and hepatitis B.
A team of researchers from the California NanoSystems Institute at UCLA has developed a new mobile phone-based device that can read ELISA plates in the field with the same level of accuracy as the large machines normally found in clinical laboratories.
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Tetramethyleneethane Equivalents: Recursive Reagents for Serialized Cycloadditions
Journal of the American Chemical Society Share
  
New reactions and reagents that allow for multiple bond-forming events per synthetic operation are required to achieve structural complexity and thus value with step-, time-, cost-, and waste-economy. Here we report a new class of reagents that function like tetramethyleneethane (TME), allowing for back-to-back [4 + 2] cycloadditions, thereby amplifying the complexity-increasing benefits of Diels–Alder and metal-catalyzed cycloadditions.
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Here’s what you’re missing. BiOptix enhanced-SPR reveals information on binding rates, dissociation and stability of your molecular interactions that conventional endpoint analysis can’t deliver. Designed for increased throughput and faster, data-rich results, we’ve simplified the tool so you can focus on your research.
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Molecular Devices introduced its first fluorescence-based microplate reader in 2000 with the Gemini brand. Patented technologies such as the dual monochromators and AutoPMT Optimization System enable higher quality results. Systems are equipped with wavelength scanning for finding the optimal excitation and emission assay settings.
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The comPOUND system comprises a high-density sample storage unit and an additional suite of specialized delivery and processing modules to enable easy integration into any compound management or screening system.
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'Stem Cell Factories' of the Future?
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Scientists from the University of Nottingham in England have discovered a fully man-made substrate that could produce billions of human embryonic stem cells and move laboratory-based research to industrial-scale biomedicine. The research, published in the journal Advanced Materials, could lead the way for what the team calls "stem cell factories" — the mass production of human pluripotent stem cells.
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Oncologists Demand Action Against Rising Cancer Drug Prices
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A group of 118 oncologists have called for measures to stop escalating cancer drug prices, adding their voices to those of other doctors and patient advocates who have demanded action in recent years.
In a commentary to be published in the journal Mayo Clinic Proceedings, the oncologists said they were responding to drug expenses that have zoomed up to 10-fold over a 15-year period ending in 2012, to more than $100,000 a year.
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Murky Results for Alzheimer's Drugs
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New data on two highly anticipated Alzheimer's disease treatments are not clear wins for either drug. Unveiled at the Alzheimer's Association International Conference, the middling results are a reminder of the daunting task of slowing down the neurodegenerative disease.
Biogen provided additional data from a Phase Ib study of aducanumab, an antibody that ties up amyloid-β, the protein responsible for the telltale plaque coating the brains of people with Alzheimer's.
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Controlling the Ionic Current Rectification Factor of a Nanofluidic/Microfluidic Interface with Symmetric Nanocapillary Interconnects
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The current rectification factor can be tailored by changing the degree of asymmetry between the fluid baths on opposite sides of a nanocapillary membrane (NCM). A symmetric device with symmetric fluid baths connected to opposite sides of the NCM did not rectify ionic current; while a NCM connected between fluid baths with a 32-fold difference in cross-sectional area produced a rectification factor of 75.
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A New Target for Depression Treatment
Lab Manager Share
  
Increasing the levels of a signaling molecule found in the brain can positively alter response to stress, revealing a potential new therapeutic target for treatment of depression, UT Southwestern Medical Center researchers said.
The study, which appears in Nature Neuroscience, determined that elevating levels of the molecule cyclic adenosine monophosphate (cAMP) in brain cells had a positive impact on stress-induced behaviors in mice.
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Nanotechnology Research Leads to Super-Elastic Conducting Fibers for Artificial Muscles, Sensors
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An international research team based at The University of Texas at Dallas has made electrically conducting fibers that can be reversibly stretched to over 14 times their initial length and whose electrical conductivity increases 200-fold when stretched.
The research team is using the new fibers to make artificial muscles, as well as capacitors whose energy storage capacity increases about tenfold when the fibers are stretched.
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The Light of Fireflies for Medical Diagnostics
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In biology and medicine, we often need to detect biological molecules. For example, in cancer diagnostics, doctors need quick and reliable ways of knowing if tumor cells are present in the patient's body. Although such detection methods exist, they often require a lot of time, work and money. EPFL scientists have chemically tweaked the enzyme responsible for the light of fireflies to make it "sniff out" target biological molecules and give out a light signal.
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Quality Control Scientist: Life Sciences
Cytoskeleton Inc.
US – CO – Denver
Biocontainment Research Associate II – Microbiology and Immunology
University of Texas Medical Branch
US – TX – Galveston
Associate Research Scientist, Stem Cell Biology
New York Stem Cell Foundation
US – NY – New York
More jobs at SLAS Career Connections
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