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SLAS Americas Council Seeks Candidates: Respond by Aug. 28
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Individuals who wish to serve on the SLAS Americas Council are invited to submit materials for consideration by midnight CT, Monday, Aug. 28. Nomination materials include a short statement of your reasons for seeking a position and an affidavit acknowledging your eligibility to serve.

The current SLAS Americas Council will review submitted materials and select a slate to fill three open spots on the Council; the slate will be presented to all SLAS members in the Americas in September. The new Council members will replace Hansjoerg Haas, Craig Schulz and Aaron Wheeler, whose terms expire in 2017.
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From the SLAS President: Getting Started on SLAS Innovation AveNEW
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"Some of the most intriguing and promising new technologies and applications can come from small, relatively unknown, entrepreneurial start-up companies," says SLAS President Scott Atkin. "Recognizing the unique value these emerging technology companies bring to our membership, SLAS offers a program specifically to provide a showcase for early stage ventures at our annual Exhibition. It's known as SLAS Innovation AveNEW."

Atkin indicates that 48 companies have been on the AveNEW since SLAS was founded. Read more in the SLAS Electronic Laboratory Neighborhood e-zine.
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Poster Abstracts Due Aug. 21 for 2017 SLAS Europe HCS Conference
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The 2017 SLAS Europe High-Content Screening (HCS) Conference + Spanish Drug Discovery Network 2017 is Sept. 19-21 in Madrid, Spain. Scientific poster abstract proposals from research scientists, engineers, academics and business leaders are being accepted until Aug. 21.

Conference topics revolve around four topics: data analysis, screening, technology and model systems. Take advantage of this opportunity to interact with a stellar HCS community in Europe.
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High-Definition Biotechnology at SLAS2018, Feb. 3-7, San Diego
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This new track focuses on the application of microfluidic, optical and molecular tools in disease biology, diagnostics, screening and translational medicine. It emphasizes state-of-the-art quantitative high-throughput and high-resolution approaches in both simple cellular systems and complex tissues.

Track sessions include "High-Definition Technology Platforms for Single Cell Analysis," "Novel Approaches to Identify Targets for Specialized Medicine" and "Genomic and Proteomic Assays and Devices for Diagnostics and Translatable Biomarker Approaches."

High-Definition Biotechnology Track chairs are Angela Cacace of Fulcrum Therapeutics and Paul Blainey of The Broad Institute, MIT. For more information about this track and nine others, visit the SLAS2018 website. Podium abstract submissions are being accepted until Aug. 7.
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A Video Snapshot of the SLAS Journals
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Members of the SLAS community speak out about their experiences with SLAS Discovery and SLAS Technology. Learn about the global reach and impact offered by the journals, the services and support provided to authors, the SLAS commitment to excellence and more from Bob Campbell, Ed Chow, Dean Ho, Lorenz Mayr and Joe Olechno.

Read the SLAS journals to advance your research, and publish in the SLAS journals to advance your professional success.
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3-Dimensional Imaging of Transparent Tissues via Metal Nanoparticle Labeling
Journal of the American Chemical Society    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Chemical probes are key components of the bioimaging toolbox, as they label biomolecules in cells and tissues. The new challenge in bioimaging is to design chemical probes for three-dimensional (3-D) tissue imaging. In this work, we discovered that light scattering of metal nanoparticles can provide 3-D imaging contrast in intact and transparent tissues. The nanoparticles can act as a template for the chemical growth of a metal layer to further enhance the scattering signal. More


Cells That Stand in the Way of HIV Cure
Lab Manager    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Every day, 17 million HIV-infected people around the world swallow pills that keep the virus inside them at bay. That is, as long as they swallow those pills every day for the rest of their life. But no matter how many drugs they take, they'll always have the virus in them, lurking in their white blood cells like a fugitive from justice. And if they ever stop, HIV will come out of hiding and bring down their immune system from the inside out, causing the disease known as AIDS. More


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Data Integrity Challenges in Pharmaceutical Manufacturing: Meeting Tomorrow's Guidelines Today
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Data integrity has long played an important role in pharmaceutical production, with robust data collection and storage fundamental to the concept of Good Manufacturing Practice (GMP). For many years, regulatory authorities such as the US Food and Drug Administration (FDA), European Medicines Agency (EMA), and China Food and Drug Administration (CFDA) have pointed to five key principles as a guide to their expectations around data integrity. More


Effects of a Major Drug Target Regulated Through Molecular 'Codes'
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A team spearheaded by Van Andel Research Institute scientists has answered a long-standing question that may lead to more effective drugs with fewer side effects for diseases ranging from heart failure to cancer. The findings, published in Cell, reveal for the first time components of a G protein-coupled receptor (GPCR) named rhodopsin bound to a signaling molecule called arrestin, both crucial pieces of the body's intricate cellular communication network. More




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RNA-Seq Used to Discriminate between Bacterial and Viral Infections
Genetic Engineering & Biotechnology News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The ability of clinicians to discriminate between bacterial and viral infections among their patients is critical, not only to administer the appropriate therapeutic intervention but to help quell the rise in a major global health threat — antibiotic resistance stemming from overuse. Unfortunately, ailments such as lower respiratory tract infections (LRTIs) symptomatically present with similar clinical symptoms, regardless of the root pathogen — making proper diagnosis difficult. More




Protein Folding: Much More Intricate Than We Thought
Chemical & Engineering News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
When he wasn't playing the viola or sailing around the Chesapeake Bay during the early 1950s, National Institutes of Health scientist Christian Anfinsen was hard at work in the lab trying to understand proteins on a molecular level. It was during this period that he wrote down a law that every biochemist still has top of mind: The sequence of amino acids in a protein is sufficient to determine its three-dimensional structure. More


Seeing More With PET Scans: New Chemistry for Medical Imaging
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Researchers have found a surprisingly versatile workaround to create chemical compounds that could prove useful for medical imaging and drug development. The chemical mechanism, discovered by scientists at the Department of Energy's Lawrence Berkeley National Laboratory and UC Berkeley, could also broaden our understanding of basic chemical reaction processes involving common helpers, called catalysts, like copper and gold. More


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Field Support Scientist
Promega Corporation
United States

Senior Science and Technology Advisor
New York University
US – NY – New York

Four Post-Doctoral Positions in Systems and Computational Neuroscience
University of Pittsburgh
US – PA – Pittsburgh

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