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Deadlines near for SLAS Screening Stem Cells 2011
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"Stem cells are the source of all tissues of the body, and understanding their properties is fundamental to our understanding of human biology in health and disease." (Harvard Stem Cell Institute website). Explore this exciting field with the experts at SLAS Screening Stem Cells 2011, Sept. 26-27 in Boston. Poster submissions are due Aug. 10 for inclusion in final program and early-bird registration discounts are
offered through Aug. 15.
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JBS: High-content analysis of CCR2 antagonists on human primary monocytes
SLAS Share
  
In the newly released JBS August issue, authors Kredel, Wolff, Hobbie, Bieler, Gierschik and Heilker analyze MCP-1 internalization into primary human monocytes using partially automated liquid handling, automated fluorescence microscopic imaging and a specific image analysis algorithm.
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Get results fast with Hamamatsu’s FDSS µCELL, an imaging-based microplate reader. This affordable, simple-to-use reader accommodates 96- or 384-well microplates for kinetic cell-based assays such as GPCR, ion channel, prolyl isomerase, transporter, and light-activated receptor or channel assays. Click here for more info.
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Aug. 8 deadline for SLAS2012 podium abstracts
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Be part of the most prestigious educational program in the field of laboratory science and technology. Submit an abstract of your recent
achievements to the SLAS First Annual Conference and Exhibition, Feb. 4-8, San Diego.
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New SLAS ELN feature on translational medicine now online
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Defining translational medicine isn't easy. According to some experts, the term has almost as many definitions as practitioners. Learn more at the new SLAS Electronic Laboratory Neighborhood feature on this topic.
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Impact of technology evolution on ion channel drug discovery
SLAS Share
  
Ronald J. Knox, Ph.D., Bristol-Myers Squibb Research, digs deep into R&D for ion channel drugs and the technologies that enabled their discovery. His Sept. 15 webinar is the second
module in a three-part SLAS virtual course. Register today.
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The Access™ laboratory workstation transforms any Echo® liquid handler into an automated system for gene expression assays with reaction volumes as low as 250 nL. MORE |
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Which is your favorite current SLAS ELN feature?
- Translational medicine
- Lab purchasing trends 2011
- Stem cells moving into the mainstream of drug discovery
- SLAS member profile - Andy Zaayenga
Click here to give
SLAS your answer
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SRU Biosystems has introduced the first and only high resolution, optical, label-free plate reader. Capable of measuring functional responses in individual cells, the SCANNER represents a new paradigm in drug discovery enabling the use of primary cells earlier in drug discovery process. Contact us to learn
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Ultra Low Attachment Surface plates feature a covalently bound hydrogel layer that effectively inhibits cellular attachment, minimizes protein absorption, enzyme activation, and cellular
activation. Corning® introduces 384 well black clear bottom Ultra Low Attachment Surface plates for HTS applications of tumor spheroid and stem cell embryoid body screening.
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Transform uHT Screening: Replace microplates with Nexar’s
in-line sample processing in Array Tape - a continuous plastic strip, serially embossed with reaction wells
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Chemists transform acids into bases
Science Daily Share
  
Chemists at the University of California, Riverside have accomplished in the lab what until now was considered impossible: transform a family of compounds which are acids into bases.
As chemistry lab sessions have taught us, acids are substances that taste sour and react with metals and bases (bases are the chemical opposite of acids). For example, compounds of the element boron are acidic while nitrogen and phosphorus compounds are basic.
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Fundamental matter-antimatter symmetry confirmed
PhysOrg Share
  
According to modern cosmology, matter and antimatter were created in equal amounts in the Big Bang at the beginning of the universe. Physicists are developing concepts to explain why
the visible universe now seems to be made entirely out of matter. On the other hand, experimental groups are producing antimatter atoms artificially to explore the fundamental symmetries between matter and antimatter.
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Proton-coupled electron transfer from tryptophan
JACS Share
  
The mechanism of proton-coupled electron transfer from tyrosine in enzymes and synthetic model complexes is under intense discussion, in particular the pH dependence of the PCET rate
with water as proton acceptor. Here we report on the intramolecular oxidation kinetics of tryptophan derivatives linked to [Ru(bpy)3]2+ units with water as proton acceptor, using laser flash-quench methods.
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Mapping the most complex object in known universe
New Scientist Share
  
It's paint-by-numbers for neuroscientists. At the Max-Planck Institute for Medical Research in Heidelberg, Germany, researchers have devised a faster way of computing the neural connections that make up the brain. Mapping out this intricate web previously depended on the human eye as no computer was powerful enough to handle the brain's complex network of 70 billion neurons and thousands of kilometers of circuits.
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Role of mitochondria in Parkinson disease
National Academy of Sciences Share
  
People with Parkinson disease, a neuromuscular disorder triggered by the progressive loss of brain cells that secrete the neurotransmitter dopamine, often harbor mutations in mitochondria found in dopamine neurons, leading to defects in energy production within those neurons. Yet precisely how the mitochondrial defects lead to the death of the neurons remains unclear.
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Researchers look to dogs to better understand bone cancer
eBio News Share
  
A new University of Minnesota discovery might help bone cancer patients fight their disease more effectively, according to new research published in the September issue of Bone. Bone cancer typically affects children; the course and aggressiveness of the disease can vary from patient to patient and is difficult to predict. Some patients respond well to conventional therapies. Others respond poorly to treatment or
their disease comes back rapidly.
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More Merck job cuts
Chemical & Engineering News Share
  
Merck will cut as many as 13,000 jobs worldwide by 2015, the firm announced, in addition to the nearly 17,000 jobs eliminated following its 2009 merger with Schering Plough. The cuts were outlined in the firm's second quarter earnings statement in which it reported a 7 percent increase in sales to $12.15 billion compared to the second quarter of 2010, with net income nearly tripling to about $2 billion for
the quarter.
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Oxygen molecules discovered in deep space
Live Science Share
  
Astronomers can finally breathe a sigh of relief: A team of scientists has discovered the first oxygen molecules in deep space, capping a nearly 230-year search for the elusive cosmic
molecule. The oxygen molecules were detected in a star-forming region of the Orion nebula, roughly 1,500 light-years from Earth, by the European Space Agency's Herschel Space Observatory.
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Tasting Scotch whisky, note by vacuum-distilled note
Popular Science Share
  
When you drink whisky, you're drinking the wood it was aged in. That's easy to understand in concept, but scientist Dave Arnold spells it out for our taste buds: He has set up his
laboratory evaporator and physically separated out the flavor components in a glass of Glenlivet so they can be sipped individually.
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The Sci-Print MP2+ is a high throughput fully automated barcode printer for labeling microtiter plates and deep well blocks.
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The HTFC® Screening
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The comPOUND system comprises a high-density sample storage unit and an additional suite of specialized delivery and processing modules to enable easy integration into any compound management or screening system.
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Affordable Benchtop Instruments:
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JALA is a multi-disciplinary international forum devoted to the advancement of technology in the laboratory.
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Benefit from scientific education, information resources, career-building
opportunities and industry and peer networking.
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