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Act Fast! Submit Your SLAS2017 Podium Abstract by Aug. 8
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Show your peers how you are leveraging the power of new technologies to achieve scientific objectives. The benefits of presenting are many, including important visibility and opportunities for feedback from elite scientific thought leaders. SLAS2017 program tracks are: Students and junior faculty may also apply for Tony B. Academic Travel Awards when they submit their podium abstracts by Aug. 8. More


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The JALA Online Catalog is Now Complete
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Thanks to the special efforts of Robin Felder (University of Virginia) and SAGE Publications, the 1996, 1997 and 1998 issues are now available online with DOI numbers, completing the full online archive, 1996-2016. The journal was originally launched as a 27-page news magazine called Laboratory Automation News (LAN).

Its genesis was fueled by founding editor Felder who says, "Being the founding editor allowed me to see the latest developments in the field long before the rest of our reading public, particularly since the Internet wasn't as prevalent at that time. In addition, I was able to make the acquaintance of emerging new contributors in the field." Today JALA publishes more than 400 pages annually in six issues. In 2017, JALA will begin its 22nd year of publication as SLAS Technology (Translating Life Sciences Innovation).
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SLAS ELN Reports: Adaptable, Accurate and Affordable — The Next Wave of Benchtop Laboratory Automation Systems
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"I think benchtop laboratory automation systems powered by open source design offer more flexibility and the ability to customize — especially in a community such as SLAS, where everyone's lab environment and needs are different," says Sam Michael, director of automation and compound management at the National Center for Advancing Translational Sciences (NCATS).

A new feature article in the SLAS Electronic Laboratory Neighborhood e-zine digs deep into the novel work at NCATS and of Felix Lenk, chair of bioprocessing engineering at Technische Universität Dresden, who focused on the Petri dish to transform his lab's medium-throughput environment. SLAS members can access Lenk's recent SLAS Webinar.
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Mark Your Calendar: Two SLAS Europe Events in November
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Plan now to attend the VIII Spanish Drug Discovery Network Meeting, November 3-4 in Santiago de Compostela, Spain; and Translating Research Ideas into Future Therapeutics Conference, November 29-30 in Leuven, Belgium.

In Spain, sessions focus on the use of more predictive model systems throughout the discovery process from early primary screening through preclinical and clinical studies. In Belgium, academic scientists, pharma open innovation groups, infrastructure providers, CROs and funders from across Europe gather to enable emerging and exciting novel drug targets.
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JBS Call for Abstracts: Special Issue on Advances in MALDI Mass Spectrometry for Drug Discovery
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Guest editors Shannon Cornett, Ph.D., of Bruker and Michael Scholle, M.S., M.B.A. of SAMDI Tech invite your manuscript proposals (abstracts) by Sept. 30 for this 2017 special issue. Proposals are used to select papers for submission and peer review.

Areas of interest include high-throughput MALDI applications; novel approaches of MALDI to study biological systems and biochemical characterization; applications of MALDI imaging for early detection of toxicity; MALDI applications for profiling cells, cell lines and biochemical samples; and MALDI applications for determining metabolism and kinetics. Invited authors will be notified by Oct. 7 and final manuscripts will be due by March 1.
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Ask The Chefs: What is The Role of Social Media in Scholarly Publishing?
The Scholarly Kitchen    Share    Share on FacebookTwitterShare on LinkedinE-mail article
It seems as though the role, value and impact of social media in scholarly communications is a continuous debate. Do researchers use social media? Does social media boost citations? Are citations really all that matter? Does social media impact the reputation of publishers, authors, or the particular discipline of study? Are some disciplines more likely than others to derive value from social media? The list of questions and the opinions and data supporting them vary greatly. More


Bacteriophage Tailspikes and Bacterial O-Antigens as a Model System to Study Weak-Affinity Protein—Polysaccharide Interactions
Journal of the American Chemical Society    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Understanding interactions of bacterial surface polysaccharides with receptor protein scaffolds is important for the development of antibiotic therapies. The corresponding protein recognition domains frequently form low-affinity complexes with polysaccharides that are difficult to address with experimental techniques due to the conformational flexibility of the polysaccharide. More


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New Gene-Editing Tool Zeros in on Multiple Genes Simultaneously
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Scientists at Yale have designed a system to modify, or edit, multiple genes in the genome simultaneously, while also minimizing unintended effects. The gene-editing "toolbox" provides a user-friendly solution that scientists can apply to research on cancer and other disciplines, the researchers said. Their study ("An Easy and Efficient Inducible CRISPR/Cas9 Platform with Improved Specificity for Multiple Gene Targeting") appears in Nucleic Acids Research. More


Race Differentiation by Raman Spectroscopy of a Bloodstain for Forensic Purposes
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Bearing in mind forensic purposes, a nondestructive and rapid method was developed for race differentiation of peripheral blood donors. Blood is an extremely valuable form of evidence in forensic investigations so proper analysis is critical. Because potentially miniscule amounts of blood traces can be found at a crime scene, having a method that is nondestructive, and provides a substantial amount of information about the sample, is ideal. More




Busting a Myth About Mechanochemical Crystallization
Chemical & Engineering News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Although it may seem counterintuitive to put a compound into a ball mill to turn it into a crystalline form, the approach nonetheless works — and adding varying amounts of liquid can determine the crystal form that results, reports a team led by Bill Jones of the University of Cambridge. Compounds of interest for materials and pharmaceuticals applications often crystallize into different forms, called polymorphs. More


Google Sister Company, Drug Maker to Develop Nerve Implants
The Associated Press via Bioscience Technology    Share    Share on FacebookTwitterShare on LinkedinE-mail article
One of Google's sister companies will team up with pharmaceuticals firm GlaxoSmithKline to develop tiny implants that can tap nerves and change their electronic signals as a way of treating chronic illnesses. GSK and Verily Life Sciences, a subsidiary of Google parent company Alphabet, have agreed to create a new company known as Galvani Bioelectronics, which will be based in Britain, with a second research hub in South San Francisco, California. More


Iron Catalysts Can Modify Amino Acids, Peptides to Create New Drug Candidates
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For medicinal chemists, making tweaks to peptide structures is key to developing new drug candidates. Now, researchers have demonstrated that two iron-containing small-molecule catalysts can help turn certain types of amino acids — the building blocks of peptides and proteins — into an array of potential new forms, even when part of a larger peptide, while preserving a crucial aspect of their chemistry: chirality, or "handedness." More


Portable Device Produces Biologic Drugs on Demand
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For medics on the battlefield and doctors in remote or developing parts of the world, getting rapid access to the drugs needed to treat patients can be challenging. Biopharmaceutical drugs, which are used in a wide range of therapies including vaccines and treatments for diabetes and cancer, are typically produced in large, centralized fermentation plants. This means they must be transported to the treatment site, which can be expensive, time-consuming and challenging to execute in areas with poor supply chains. More


Career


Strategic Product Management Director – Fermentation/Bioreactor Technologies
Sartorius Stedim Biotech Group
Europe (choice of four locations)

Analytical Tech Transfer Specialist
GSK
US – PA – King of Prussia

Senior Research Scientist (Human Metabolism)
Dole Food Company
US – NC – Kannapolis

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