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Aug. 12, 2020

SLAS NEWS

CRISPR is Eating the World Not really, but you get the idea. In the latest New Matter: Inside the Minds of SLAS Scientists podcast, Janice Chen, Ph.D., CTO of Mammoth Biosciences, joins Mike Tarselli to talk about how to launch a start-up, how to discover new CRISPR nucleases and how to turn lab discoveries into products that benefit human health. LISTEN NOW

New LIVE Webinar Event in Two Weeks SLAS Just because in-person events are on hold, doesn’t mean live events are. Join Jayme L. Dahlin, M.D., Ph.D., (Brigham and Women’s Hospital) on Thursday, August 27 at 12:00 p.m. CDT, for his live presentation “Compound-Mediated Interferences in Homogeneous Proximity Assays.” Dahlin will cover the basic principles of: homogeneous proximity assays, common sources of compound-mediated interference in homogeneous proximity assay and counter-screens and other strategies to mitigate and identify compound-mediated assay interferences in homogeneous proximity assays. Registration is now open and is FREE for SLAS Premier Members and $20 for all others. LEARN MORE

Be a Part of the First-Ever Digital SLAS International Conference and Exhibition SLAS Last week it was announced that the 10th Annual SLAS International Conference and Exhibition (January 25-27, 2021) will be going digital. While the event platform has changed, opportunities to get involved have not. SLAS2021 will offer plenty of presentation, exhibition, sponsorship, award and networking opportunities to go along with the innovative and leading edge life sciences and technology programming and new product announcements attendees have come to expect. Plus, SLAS Premier Members can register for FREE! Registration will go live in October. View up-to-date sponsor and exhibitor details. VIEW THE SLAS2021 WEBSITE

Now Accepting: SLAS2021 Abstract Submissions for Live Talk or Poster SLAS Each year scientists, engineers, academics, graduate students, post-docs and business leaders from academia, government and industry are invited to submit podium and poster abstracts in 10 cutting-edge educational tracks. This year, while the format of SLAS2021 has changed, opportunities to be recognized for significant research have not. See below for links to important call for abstracts info, including the coveted Tony B. Academic “Travel” Award. Deadlines below: Podium abstract submission deadline: Monday, September 14 Tony B. Academic Travel Award podium submission deadline: Monday, September 14 Tony B. Academic Travel Award poster submission deadline: Monday, October 5 Poster abstract submission deadline: Monday, October 19 VIEW COMPLETE CALL FOR ABSTRACTS DETAILS

SPONSORED VIDEO The Ultimate Laboratory Microplate Mover The Thermo Scientific™ Orbitor™ RS2 microplate mover is a collaborative bench-top mover that provides unbeatable reliability and improved process efficiency. It’s innovative bi-directional telescoping arm coupled with it’s expansive 360° workspace provide exceptional reach and precision, making the Orbitor RS2 your trusted laboratory productivity partner. WATCH VIDEO

Share Your Insights; Become a Mentor SLAS SLAS has created a new portal within CONNECTED to help experienced professionals within the scientific community match with those just starting out and looking to advance their career. SLAS Mentor Match was developed to provide a connection point for mentors to share knowledge and give support to mentees who in turn benefit from engaging with industry leaders and seasoned scientists. Enrolling as a mentor or mentee is free, but participants must be SLAS members. ENROLL AS A MENTOR

Two New August Journals = Two New Journal Podcasts SLAS On the heels of the release of the August editions of SLAS Discovery and SLAS Technology come their companion podcast episodes. Tune into SLAS Discovery Author Insights and SLAS Technology Authors Talk Tech for the latest behind-the-lab insights of the journals’ lead articles. SLAS Discovery Author Insights: Comparison of Cell and Organoid-Level Analysis of Patient-Derived 3D Organoids to Evaluate Tumor Cell Growth Dynamics and Drug Response SLAS Technology Authors Talk Tech: Carbohydrate Structure Analysis: Methods and Applications

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Calendar of Important Dates SLAS Events SLAS2021 Digital Conference and Exhibition January 25 – 27, 2021 Save the Date! What Does it Mean to be a WomXn of SLAS? SLAS Member Meet-Up Wednesday, August 26 11:00 a.m. CDT Compound-Mediated Interferences in Homogeneous Proximity Assays Webinar Thursday, August 27 12:00 p.m. CDT Save the Date for the September Webinar Series Redefining Pre-Clinical Testing in Oncology: Why We Need to Go 3D September 10 7:00 a.m. CDT The Roadmap for the Next Generation Oncology: The Contribution of Tridimensional Models September 15 7:00 a.m. CDT Patient Derived Scaffolds (PDS) in Cancer Research and Drug Discovery September 22 7:00 a.m. CDT

HEADLINES

Colloidal Synthesis of Nanohelices via Bilayer Lattice Misfit Journal of the American Chemical Society Helical structures are ubiquitous in natural and synthetic materials across multiple length scales. Excellent and sometimes unusual chiral optical, mechanical, and sensing properties have been previously demonstrated in such symmetry-breaking shape, yet a general principle to realize helical structures at the sub-100 nm scale via colloidal synthesis remains underexplored. In this work, we describe the wet-chemical synthesis of monodisperse nanohelices based on gadolinium oxide (Gd2O3). READ MORE

SPONSORED CONTENT Promoted by Corning • Is your lab reopening? Check out these tips to keep you safe during a pandemic. • Ramping up drug, vaccine and infectivity testing with airway organoids. • 3D cell culture could drive the fight against infectious diseases • Why HUB organoids are key to advancing personalized cancer therapies • Organoid vs. spheroid: What’s the difference?

Rapid COVID-19 Testing Breaks Free From the Lab Chemical & Engineering News Countries emerging from COVID-19 lockdowns face a thorny dilemma. People are desperate to return to their workplaces and schools, but resuming public life also risks a catastrophic resurgence of the virus. One way to reduce that risk is to expand the scope of diagnostic testing. So far, the majority of coronavirus tests have been conducted on samples from people with symptoms of COVID-19, such as cough or fever. READ MORE

AI Invents New 'Recipes' for Potential COVID-19 Drugs Science Magazine As scientists uncover drugs that can treat coronavirus infections, demand will almost certainly outstrip supplies—as is already happening with the antiviral remdesivir. To prevent shortages, researchers have come up with a new way to design synthetic routes to drugs now being tested in some COVID-19 clinical trials, using artificial intelligence (AI) software. The AI-planned new recipes—for 11 medicines so far—could help manufacturers produce medications whose syntheses are tightly held trade secrets. READ MORE

PRODUCT SHOWCASE

Convenient. Consistent. Certain. Matrigel matrix-3D plates are a pre-coated, convenient, off the shelf option that improve productivity and consistency in homogenous assays where 3D structures are grown and assayed directly in the plate. Using a pre-coated option eliminates the need to handle small volume ECM dispensation and helps reduce workflow steps LEARN MORE Biospecimen Acquisition to Support Research The Cooperative Human Tissue Network (CHTN) is a unique NCI supported resource that provides human tissues and fluids prospectively from surgeries, autopsies and other routine procedures to investigators who utilize human biospecimens in their research. Visit our website for more information and pricing or contact our Central Coordinator. LEARN MORE

Russia Approves World's First Coronavirus Vaccine The Scientist Russian President Vladimir Putin announced that his country had won the global race to approve a vaccine against COVID-19, several news outlets have reported. Despite having only been in clinical trials for less than two months, the vaccine developed by the Gamaleya Institute in Moscow is safe, Putin said at a televised cabinet meeting, noting that it has already been given to one of his daughters, according to Reuters and The Washington Post. READ MORE

Fast Tracking Drug Therapies for Viral Infections and Cancer Genetic Engineering & Biotechnology News Researchers at Simon Fraser University and a group of international collaborators say discovering antiviral and anticancer drugs may soon be faster and cheaper as they describe in their new paper “A short de novo synthesis of nucleoside analogs” in Science. For the past 50 years, scientists have used man-made, synthetic, and nucleoside analogues to create drug therapies for diseases that involve the cellular division and/or the viral reproduction of infected cells. READ MORE

PRODUCT SHOWCASE Understanding your Sample Management Needs Evotec’s broad range of sample management capabilities in drug discovery and bioanalysis, many years of experience and continued investments in innovation and technology enable us to meet all customers’ needs and deadlines. Find out how the expertise of a global leader in sample management can help your projects. LEARN MORE

Breaking Molecular Traffic Jams With Finned Nanoporous Materials Science Daily Thousands of chemical processes used by the energy industry and for other applications rely on the high speed of catalytic reactions, but molecules frequently are hindered by molecular traffic jams that slow them down. Now an entirely new class of porous catalysts has been invented, using unique fins to speed up the chemistry by allowing molecules to skip the lines that limit the reaction. This discovery was published in Nature Materials. READ MORE

Sustainable Chemistry at the Quantum Level Lab Manager Developing catalysts for sustainable fuel and chemical production requires a kind of Goldilocks Effect—some catalysts are too ineffective while others are too uneconomical. Catalyst testing also takes a lot of time and resources. New breakthroughs in computational quantum chemistry, however, hold promise for discovering catalysts that are "just right" and thousands of times faster than standard approaches. READ MORE

Understanding the Surface Chemistry of SARS-CoV-2 Phys.org Better understanding of the surface chemistry of the SARS-CoV-2 virus is needed to reduce transmission and accelerate vaccine design. Researchers at Michigan Tech, TÜV SÜD UK National Engineering Laboratory and University of Edinburgh call for increased research on virus surface stability and interaction in "Surface Chemistry Can Unlock Drivers of Surface Stability of SARS-CoV-2 in Variety of Environmental Conditions" in the journal Cell Press. READ MORE

CAREER CONNECTIONS

Job Seekers: Post your résumé and sign up for new job alerts by keyword. Employers: Search résumés, post an open position, internship or post-doc opportunity. SLAS Premier and Corporate Members get a discount on all new job postings. Scientific Director SLAS US – IL – Oak Brook Research Assistant Professor East Tennessee State University US – TN – Johnson City Bioinformatics Scientist Harvard University Faculty of Arts and Sciences US – MA – Cambridge Search Jobs at SLAS Career Connections READ MORE

THANK YOU 2020 SLAS CORPORATE MEMBERS

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