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Certified UPS’s to protect your laboratory’s critical instrumentation and resolve current and potential power issues.
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Boost your career or find the perfect candidate. SLAS Career Connections offers both online and in-person career services.
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The SLAS Market Place offers access to new and existing technology products and services for your laboratory.
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SLAS Call for Journal Papers!
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JALA and JBS accept original scientific manuscript submissions from SLAS members and nonmembers. A total of 85 percent of SLAS members surveyed say JALA and JBS are important and meet or exceed their needs. Share your achievements in these highly regarded, peer-reviewed journals.
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 Stem Cell Opponents? Give Me Your Best Shot.
SLAS Share
That's the title of the open letter SLAS2013 keynote speaker Charles Sabine authored for the Aug. 3 issue of Cell Stem Cell. "And what about hope? Do we HD [Huntington's disease] families have that? The answer to that question lies in the hands of not only the researchers who are the custodians of new science, but also the legislatures, executives, and churches that will dictate how our societies treat the infirm in the 21st century," Sabine states.
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Nanodiamonds Battling Cancer: New SLAS ELN feature
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"The concept of nanodiamonds as a diagnostic and therapeutic tool is fascinating," says SLAS Director of Education Steve Hamilton, Ph.D., "and like the SLAS scientific community, it embraces an enthusiastic versatility that combines intellectual curiosity with an inspiring sense of innovation and cooperation." The new SLAS Endowed Fellowship at UCLA helps researchers pioneer new technology for nanomedicine through a vibrant international and interdisciplinary network.
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SLAS2013 Online Group Registration Open
SLAS Share
A discount of 20 percent off of each full-conference registration is available for groups of five registrants from the same company who pre-register at the same time. This discount program is only to those who pre-register for the conference online and will not be available at the door. SLAS2013 will be held Jan. 12-16 in Orlando, Fla.
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The Nexar® system provides inline sample storage, liquid handling, incubation, and detection. High throughput, miniaturized reaction volumes and walk-away operation. Check it out!
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We offer the industry’s largest human and ortholog GPCR stable cell line collection and hundreds of customizable options for your functional and binding screening and profiling needs, with the highest quality and fastest turnaround. More>> Email: info@multispaninc.com
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SLAS Special Interest Groups plan SLAS2013 meetings
SLAS Share
Many SLAS2012 participants expressed interest in attending more than one SIG meeting at future conferences. In response, the SLAS2013 Annual Conference Scientific Program Committee has scheduled three different time slots during which SIG meetings will be held. Fifteen SIGs currently are selecting topics and speakers; watch for program updates and plan to participate. See SLAS.org for descriptions of each Special Interest Group.
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 Two weeks left to submit to JALA & JBS Art of Science contest
SLAS Share
Aug. 31 is fast approaching. Submit your best original scientific image for a chance to win the new iPad. Read about last year's winners in SLAS ELN and/or watch a short video featuring the 2012 winners. Then, send SLAS your best! Entries are welcome from SLAS members and nonmembers.
Pictured on the right is the 2012 JAJA & JBS grand prize image by Zhang Ling of Tohoku University, Sendai, Japan.
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Bringing stem cells to the forefront
Drug Discovery & Development Share
Stem cells offer unique opportunities for researchers to study the reaction of drugs applied to human tissues. Moreover, stem cells can model healthy or diseased states, as well as provide the ability to genetically modify cells before drug treatment. To make the most of these cells, however, researchers need a variety of tools and techniques. This article explores several new tools and reveals ongoing aspirations.
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New insights into the mechanism of amine/nitroxide cycling during the hindered amine light stabilizer inhibited oxidative degradation of polymers
Journal of the American Chemical Society Share
High-level ab initio molecular orbital theory calculations are used to identify the origin of the remarkably high inhibition stoichiometric factors exhibited by dialkylamine-based radical-trapping antioxidants. We have calculated the free energy barriers and reaction energies at 25, 80, and 260°C in the gas phase and in aqueous solution for a broad range of reactions that might, potentially, be involved in amine/nitroxide cycling.
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SRU Biosystems has introduced the first and only high resolution, optical, label-free plate reader. Capable of measuring functional responses in individual cells, the SCANNER represents a new paradigm in drug discovery enabling the use of primary cells earlier in drug discovery process. Contact us to learn more.
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Get results fast with Hamamatsu’s FDSS µCELL, an imaging-based microplate reader. This affordable, simple-to-use reader accommodates 96- or 384-well microplates for kinetic cell-based assays such as GPCR, ion channel, prolyl isomerase, transporter, and light-activated receptor or channel assays. Click here for more info.
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At Molecular Devices, we understand your desire for a top-of-the-line multi-mode microplate reader while balancing an ever-tightening budget. Get the reliability and sensitivity your lab deserves at the price-point you need from a name you trust. Learn more at info.moleculardevices.com
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Molecular determinants of selectivity and efficacy at the dopamine D3 receptor
Journal of Medicinal Chemistry Share
The dopamine D3 receptor (D3R) has been implicated in substance abuse and other neuropsychiatric disorders. The high sequence homology between the D3R and D2R, especially within the orthosteric binding site (OBS) that binds dopamine, has made the development of D3R-selective compounds challenging.
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Biometric bracelet lets a medical device recognize its wearer
Technology Review Share
A device that measures someone's unique response to a weak electric signal could let medical devices such as blood-pressure cuffs automatically identify the wearer and send measurements straight to his or her electronic medical record. Computer scientist Cory Cornelius at Dartmouth College, in New Hampshire, has developed a wristwatch-like device that measures a person's "bioimpedance" to identify him or her to medical monitoring devices.
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President Obama honors outstanding early-career scientists
White House Share
President Barack Obama named 96 researchers as recipients of the Presidential Early Career Awards for Scientists and Engineers, the highest honor bestowed by the United States government on science and engineering professionals in the early stages of their independent research careers.
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A vaccine for heart disease? New discovery points up this possibility
Medical Xpress Share
Most people probably know that heart disease remains the nation's No. 1 killer. But what many may be surprised to learn is that cholesterol has a major accomplice in causing dangerous arterial plaque buildup that can trigger a heart attack. The culprit? Inflammatory cells produced by the immune system.
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TTP Labtech’s acumen eX3 can analyse over 40 images/second – allowing you to profile compound libraries in hours. Don’t sacrifice throughput for high content. MORE
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Modular automation for tube and vial feeding, labeling, and racking including 600 dpi printer resolution, 'whisper' feed automatic feeders, and robotic racking systems. MORE
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Protein with liquid built in could be key to life without water
Popular Science Share
For all our attempts to find it on other worlds, water may not be the most essential molecule for life, a new study suggests. A protein that brings oxygen to muscle can function without it, using a synthetic polymer in its place.
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Faltering drug candidates have cost Pfizer, BMS and others hundreds of millions of dollars
Chemical & Engineering News Share
Several big pharmaceutical firms have been hit by clinical setbacks that are weakening their drug pipelines at a time when older products are falling to competition from generics. Pfizer and its partners Johnson & Johnson and Elan have discontinued development of bapineuzumab, an antibody against amyloid-β, a protein that makes up the hallmark plaque in the brains of people with Alzheimer's disease.
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Stem cells responsible for higher brain function found
New Scientist Share
Scientists have identified a type of stem cell that appears to be responsible for the neurons involved in higher brain function. The discovery may pave the way for new treatments for autism and schizophrenia. The mammalian cerebral cortex is layered like an onion, with neurons in different layers responsible for different levels of cognitive function.
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Top 10 biotech jobs most in demand over next decade
Genetic Engineering & Biotechnology News Share
Here are the positions the biotech industry will most need to fill over the next 10 years. Is yours on the list?
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New light shed on important metabolite in bacteria
Science Daily Share
Scientists from the research groups of Prof. Dr. Susana Andrade and Prof. Dr. Oliver Einsle, members of the Institute of Organic Chemistry and the Cluster of Excellence BIOSS, the Centre for Biological Signalling Studies of the University of Freiburg, have collected the first precise data ever on the function of a transport protein for formate — an important metabolite in bacteria.
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Reproducible PPM level detection of sulfur by ICP-OES
Warwick Analytical Service Share
Warwick Analytical Service has developed a proprietary Inductive Coupled Plasma — Optical Emission Spectroscopy sample preparation protocol allowing regular, reproducible detection of sulfur at trace levels of only tens of parts-per-million. The new protocol provides an affordable alternative to ICP-MS based methods for determining low ppm levels of sulfur in chemicals, pharmaceuticals, natural products, fuels, geological and nanoparticulate materials.
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This application note by INTEGRA discusses and demonstrates how the advent of adjustable spacing multichannel pipettes presents labs with a valuable new tool for accelerating tasks where samples need reformatting while at the same time increasing precision, reliability and comfort of the pipetting procedure. MORE
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ALPAQUA® offers 24-well, 96-well & 384-well magnet plates with integrated spring technology for touch-off dispensing and complete supernatant removal while eliminating costly tip crashes and occlusions. Strong NdFeB magnets enable rapid, reliable bead capture and retention. Alpaqua magnet plates are SBS compliant and compatible with many liquid handlers, plate hotels & stackers.
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