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Text version   RSS   Subscribe   Unsubscribe   Archive   Media Kit August 16, 2017

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Register Today for the SLAS Europe High-Content Screening Conference, Sept. 19-20, Madrid
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The SLAS High-Content Screening Conference brings together scientists, technologists, researchers, academics and data informatics professionals from many countries to share their experience and latest results in high-throughput microscopy and data analysis. The scientific chairs indicate there is currently a revolution in biology with the emergence of several ground-breaking technologies, ranging from stem cell culture, organoids, genome engineering to engineering advancements such as microfluidics, bioprinting, imaging modalities and sequencing methods.

"These extraordinary advances in the various fields are being integrated into research projects with astounding results, and this conference will offer some examples of how scientists are integrating these advances into their research to produce novel insights into biology." On Thursday, Sept. 21, the annual Spanish Drug Discovery Network meeting is being held at the same venue.
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Make a Bigger Splash in Life Sciences with the SLAS Journals
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Thousands of researchers, scientists and engineers count on the rigorously peer-reviewed SLAS Discovery (Advancing Life Sciences R&D) and SLAS Technology (Translating Life Sciences Innovation) journals to gain scientific insights; increase productivity; elevate data quality; reduce process cycle times; and enable research and development that would otherwise be impossible.

SLAS Technology explores ways in which scientists adapt advancements in technology for scientific exploration and experimentation. SLAS Discovery reports how scientists develop and utilize novel technologies and/or approaches to provide and characterize chemical and biological tools to understand and treat human disease. Both journals are backed by the high-quality education standards of SLAS. Read the SLAS journals to advance your research. Publish in the SLAS journals to advance your professional success.
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SLAS2018 Poster Abstracts Due Sept. 25 for Tony B. Academic Travel Award Consideration
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Since SLAS was founded in 2010, SLAS Tony B. Academic Travel Awards have provided funding to enable 337 students, post-docs and early career professionals from around the world to participate in SLAS International Conferences and Exhibitions. The Tony B. Academic Award is one way SLAS ensures that up-and-coming researchers who demonstrate outstanding potential can learn from and interact with life sciences discovery and technology community leaders.

If selected for a Tony B. Award at SLAS2018 (Feb. 3-7 in San Diego, CA), travel, hotel accommodations and conference registration are provided to the primary author of a submitted podium or poster abstract. Abstracts and applications are due Sept. 25 for poster presentations; the podium deadline has passed.
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How Open Access Publishing Can Benefit Authors
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A short video by SAGE Publishing defines open access and explains its potential benefits to authors.

The SAGE Choice open access publishing option is available for a fee to SLAS Discovery, SLAS Technology and other SAGE authors who wish to make their research article available to the public immediately upon publication.
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Four New Job Announcements Just Posted to SLAS Career Connections
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Visit this targeted employment exchange regularly to keep up to date with opportunities. Job seekers can post resumes and browse job openings for free (two to three new, targeted postings each week!).

Employers can find new talent by reviewing posted resumes for free and attract new talent by posting job openings for a fee. Note: SLAS Corporate Members receive a 50 percent discount on job postings.
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New Version of DNA Editing System Corrects Underlying Defects in RNA-based Diseases
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Until recently, the CRISPR-Cas9 gene editing technique could only be used to manipulate DNA. In a 2016 study, University of California San Diego School of Medicine researchers repurposed the technique to track RNA in live cells in a method called RNA-targeting Cas9 (RCas9). In a new study, published August 10 in Cell, the team takes RCas9 a step further: they use the technique to correct molecular mistakes that lead to microsatellite repeat expansion diseases. More


Study: Published Science Begets Commercial Innovation
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After scrutinizing the connections between scientific papers and U.S. patents, researchers conclude that most published studies, notably those in some areas of chemistry, eventually support marketable technological advances. Although this link may seem obvious to many scientists, a quantitative analysis of this type has never been carried out before. It shows that basic science experiments "seem to pay off in the flow of knowledge forward to some future marketplace application," says coauthor Benjamin F. Jones. More


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Creation of a Synthetic Ligand for Mitochondrial DNA Sequence Recognition and Promoter-Specific Transcription Suppression
Journal of the American Chemical Society    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Synthetic ligands capable of recognizing the specific DNA sequences inside human mitochondria and modulating gene transcription are in increasing demand because of the surge in evidence linking mitochondrial genome and diseases. In the work described herein, we created a new type of mitochondria-specific synthetic ligand, termed MITO-PIPs, by conjugating a mitochondria-penetrating peptide with pyrrole-imidazole polyamides (PIPs). More


Fundamental and Practical Insights on the Packing of Modern High-Efficiency Analytical and Capillary Columns
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New stationary phases are continuously developed for achieving higher efficiencies and unique selectivities. The performance of any new phase can only be assessed when the columns are effectively packed under high pressure to achieve a stable bed. The science of packing columns with stationary phases is one of the most crucial steps to achieve consistent and reproducible high-resolution separations. More




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New Technique Searches 'Dark Genome' for Disease Mutations
Lab Manager    Share    Share on FacebookTwitterShare on LinkedinE-mail article
When doctors can't find a diagnosis for a patient's disease, they turn to genetic detectives. Equipped with genomic sequencing technologies available for less than 10 years, these sleuths now routinely search through a patient's DNA looking for mutations responsible for mysterious diseases. Despite many successes, the search still comes back empty more often than not. In fact, disease-causing mutations are found in only about one in three to four patients suspected of having a strongly genetic condition. More


New Microscope Technique Reveals Internal Structure of Live Embryos
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University of Illinois researchers have developed a way to produce 3-D images of live embryos in cattle that could help determine embryo viability before in vitro fertilization in humans. Infertility can be devastating for those who want children. Many seek treatment, and the cost of a single IVF cycle can be $20,000, making it desirable to succeed in as few attempts as possible. Advanced knowledge regarding the health of embryos could help physicians select those that are most likely to lead to successful pregnancies. More




Researchers Discover New Class of Chemical Reaction
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A new study led by Michael P. Burke, assistant professor of mechanical engineering at Columbia Engineering, has identified the significance of a new class of chemical reactions involving three molecules that each participate in the breaking and forming of chemical bonds. The reaction of three different molecules is enabled by an "ephemeral collision complex," formed from the collision of two molecules, which lives long enough to collide with a third molecule. More


Stem Cell Injections Rejuvenate Aging Rat Hearts
Genetic Engineering & Biotechnology News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Researchers at the Cedars-Sinai Heart Institute have shown that injecting cardiac stem cells from young rats into the hearts of old rats can help to reverse the natural cardiac aging process. Results from the studies, led by Eduardo Marbán, M.D., Ph.D., director of the Cedars-Sinai Heart Institute, suggest that similar treatments might one day be used to prevent age-related heart function decline and cardiovascular disease in humans. More


Career


Automation Scientist
Recursion Pharmaceuticals
US – UT – Salt Lake City

Lab Automation Engineer 1
Calico
US – CA – South San Francisco

Lab Manager
Research Center Caesar
Germany – Bonn

Search Jobs at SLAS Career Connections


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