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  Mobile version   RSS   Subscribe   Unsubscribe   Archive   Media Kit Aug. 21, 2013

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Inspired Scientists: SLAS2013 Student Poster Award Winners Share their Stories
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Although they come from different backgrounds — one is a former high school teacher, another is a chemical engineer — these winners share a common sense of curiosity and love of science. Learn how the SLAS competition offered Kamran Honarnejad, Michael T. Jacobs and Yang Wu chances to advance their work and actively engage as the next generation of laboratory science and technology leaders. Oct. 28 is the deadline for the SLAS2014 Student Poster Competition; those wishing to apply for the SLAS Tony B. Academic Travel Award must submit their poster abstracts by Sept. 16. More

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JBS September issue now at JBS Online for members and subscribers
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"A Label-Free LC/MS/MS-Based Enzymatic Activity Assay for the Detection of Genuine Caspase Inhibitors and SAR Development," "Development of a Pharmacodynamic Assay Based on PLCγ2 Phosphorylation for Quantifying Spleen Tyrosine Kinase (SYK)–Bruton's Tyrosine Kinase (BTK) Signaling" and "Development of a Quantitative Assay Amenable for High-Throughput Screening to Target the Type II Secretion System for New Treatments against Plant-Pathogenic Bacteria" are among the original research articles in the September issue. SLAS Biomolecular Sciences Section members and JBS subscribers can view the issue online now. More

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Ensure your coworkers have instant online access to JALA and JBS
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Encourage your company or university library to give your team full access to 18 years worth of original, peer-reviewed research. JALA explores ways scientists adapt advancements in technology for scientific exploration and experimentation. JBS reports how scientists use adapted technology to pursue new therapeutics for unmet medical needs. Together they complete the laboratory science and technology continuum. Complete the simple JALA and JBS Institutional Recommendation Forms today. More

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SLAS presents four speakers at MipTec 2013, Sept. 24-26
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Nanobiopharmaceuticals: Helping Complex Molecules to Reach their Targets
M.J. Alonso, University of Santiago de Compostela, Santiago de Compostela, ES
Peptide Therapeutics Track

The Signaling Networks Regulating Cell Shape
C. Bakal, The Institute of Cancer Research, London, UK
High Content Screening Track

Adapting Human Pluripotent Stem Cells to High Content Screening: Challenges and Applications
S. Desbordes, Helmholtz Zentrum, Munich, DE
High Content Screening Track

Peptides as Drugs, An Academical Point of View
J. Martinez, University of Montpellier, Montpellier, FR
Peptide Therapeutics Track

SLAS also will invite the winner of the MipTec student poster competition to SLAS2014 as part of the SLAS Young Scientist Delegate program.
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SLAS2014 keynoter's blog: Topolog
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“Stents, precedents, and presidents” is the title of Eric Topol’s latest post on Topolog, where he leads listeners through the cardiovascular interventions in former U.S. Presidents Bill Clinton (2004) and George W. Bush (2013) and reviews standards of care and individualized medicine. Cardiologist Topol, editor-in-chief of theheart.org and director of Scripps Translational Science Institute, translates clinical research in cardiology to daily practice on Topolog. His SLAS2014 presentation is set for Monday, Jan. 20, in San Diego. More


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The STEM gender gap
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AudioBriefThe number of girls and women studying the sciences has steadily increased each year, but there is still a gender gap in higher education and the work force. Researchers Andresse St. Rose and Catherine Riegle-Crumb and Linda Kekelis, executive director of Techbridge, discuss the social and environmental factors that contribute to this disparity. More

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Technical and implementation issues in using next-generation sequencing of cancers in clinical practice
British Journal of Cancer    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Next-generation sequencing of cancer genomes promises to revolutionize oncology, with the ability to design and use targeted drugs, to predict outcome and response, and to classify tumors. It is continually becoming cheaper, faster and more reliable, with the capability to identify rare yet clinically important somatic mutations. Technical challenges include sequencing samples of low quality and/or quantity, reliable identification of structural and copy number variation, and assessment of intratumor heterogeneity. More

For blood substitutes, bigger may be better
Chemical & Engineering News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Doctors have dreamed of artificial blood substitutes for when accident victims or wounded soldiers need blood transfusions and donor blood supplies are thin. But many proposed substitutes have failed because they restrict blood flow by causing vessels to narrow. Now researchers report a new oxygen carrier built from animal hemoglobin that could get around this constriction problem. More

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Chemists devise new way to prepare molecules for drug testing
Phys.org    Share    Share on FacebookTwitterShare on LinkedinE-mail article
James Bond had his reasons for ordering his martinis "shaken, not stirred." Similarly, drug manufacturers need to make sure the molecules in a new drug are arranged in an exact manner, lest there be dire consequences. Specifically, they need to be wary of enantiomers, mirror-image molecules composed of the same atoms, but arranged differently. "One mirror image could be therapeutic while another could be poisonous," said Dr. Mark R. Biscoe, assistant professor of chemistry at The City College of New York. More

Three-phase electroextraction: A new (online) sample purification and enrichment method for bioanalysis
Analytical Chemistry    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The migration and at the same time enrichment of analytes from a liquid aqueous sample donor phase through an immiscible organic solvent layer acting as a filter phase into a liquid aqueous acceptor phase is enabled by the application of an electric field between the donor and acceptor phase. The organic filter phase acts as a purification filter, which prevents, for example, proteins from migrating into the acceptor phase. More


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The use of microspheres in parenteral drug delivery
By Dr. Afsaneh Motamed-Khorasani    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Drug formulation and delivery is an important process in drug development, where targeted and sustained drug release plays a crucial role in this aspect. Recently, microsphere systems have been used for the sustained release of proteins and chemical drugs. Microspheres provide direct treatment and are capable of delivering the drug to the disease site with lower drug dosing and negligible systemic side effects. More

Information toolboxes with useful information for testing labs
METTLER TOLEDO     Share    Share on FacebookTwitterShare on LinkedinE-mail article
Testing labs are under increasing pressure to analyze and process more and more samples per day. Increased productivity and ease of use can often be achieved by knowing the instruments inside out, and by having access to additional how-to information, tips & tricks and application notes and white papers. To aid those working in testing labs, METTLER TOLEDO has recently launched four toolboxes: sample preparation, liquid handling, water and moisture content determination and thermal analysis. More

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Stepwise ligand exchange for the preparation of a family of mesoporous MOFs
Journal of the American Chemical Society    Share    Share on FacebookTwitterShare on LinkedinE-mail article
A stepwise ligand exchange strategy is utilized to prepare a series of isoreticular bio-MOF-100 analogues. Specifically, in situ ligand exchange with progressively longer dicarboxylate linkers is performed on single crystalline starting materials to synthesize products with progressively larger mesoporous cavities. The new members of this series of materials, bio-MOFs 101–103, each exhibit permanent mesoporosity and pore sizes ranging from 2.1–2.9 nm and surface areas ranging from 2704 to 4410 m2/g. More

Mouse heart beats again thanks to human stem cells
New Scientist    Share    Share on FacebookTwitterShare on LinkedinE-mail article
A newly beating heart is part-mouse, part-human. For the first time, a mouse heart has been made to pulse again by stripping it of its own cells and rebuilding it with human ones. To create the hybrid heart, Lei Yang at the University of Pittsburgh and colleagues took the heart from a mouse and, in a process that lasted 10 hours, removed all its cells. The remaining protein scaffold was then repopulated with human heart precursor cells — stem cells that had differentiated into the three types of cell required for a heart. More



Effects of Parkinson's-disease mutation reversed in cells
eBioNews    Share    Share on FacebookTwitterShare on LinkedinE-mail article
UC San Francisco scientists working in the lab used a chemical found in an anti-wrinkle cream to prevent the death of nerve cells damaged by mutations that cause an inherited form of Parkinson's disease. A similar approach might ward off cell death in the brains of people afflicted with Parkinson's disease, the team suggested in a study reported online in the journal Cell on Aug. 15. More

Dynamics of liquid metal particles examined at nanoscale
Science Daily    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Two NJIT researchers have demonstrated that using a continuum-based approach, they can explain the dynamics of liquid metal particles on a substrate of a nanoscale. "Numerical simulation of ejected molten metal nanoparticles liquified by laser irradiation: Interplay of geometry and dewetting," appeared in Physical Review Letters. More


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Precision Agriculture Scientist
Lincoln Agritech
New Zealand

Sales Representative – Laboratory Implementation
BioTek Instruments
US – CA – San Francisco

Senior Instrument Software Engineer/Manager
Artel
US – ME – Westbrook

More jobs at SLAS Career Connections


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