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Text version   RSS   Subscribe   Unsubscribe   Archive   Media Kit August 23, 2017    SLAS2018    Moving? New job? Let SLAS know.      







Free SLAS Webinar on 3D Assays: Sept. 26
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Brad Larson of BioTek Instruments and Mark Rothenberg of Corning Life Sciences share their expertise on the cellular microenvironment and its importance when developing and screening cell-based assays using primary, stem cell and immortalized cultures in 3D systems. "3-Dimensional Assays: What Must Be Done for Setting Up and Validating for Downstream Microplate Reader and Imaging Applications" will be presented live Sept. 26 and then available on demand. This SLAS Webinar is open to members and non-members alike.

Read more about the topic in the SLAS Discovery Special Issue on 3D Cell Culture, Drug Screening and Optimization (featuring free access to select articles courtesy of Corning) and the SLAS Electronic Laboratory Neighborhood feature article. Register today!


Test Your Research Impact Muscles
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Think you have what it takes to ensure your research has impact? Take this quick test at Kudos to see how "ready for impact" you are and discover what more you can do to ensure your work gets found, read and cited.

You could win $4,000 worth of research infographics for your institution or one of five $100 U.S. Amazon vouchers.

Last Call for SLAS Board of Directors Applications
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The SLAS Nominations Committee will soon select three individuals to join the SLAS Board of Directors for three-year terms of service beginning in 2018. Candidate applications for the SLAS Board of Directors are being accepted from the membership community through Aug. 25, 2017.

All candidates must have the capacity and commitment to serve, and meet the required criteria outlined in the SLAS Strategic Plan, SLAS Board of Directors Selection Policy and the SLAS Bylaws. The new board members will replace those completing their terms: Scott Atkin, Michele Cleary and Susan Lunte.

Reliably screen CRISPR modified lines

Keep your CRISPR/Cas gene editing workflow moving smoothly with fast and reliable detection of positive clones. The AccuCleave™ T7CE Kit uses an optimized heteroduplex cleavage assay to quickly identify and characterize CRISPR induced modifications with fast and reliable detection on the Fragment Analyzer™ Automated CE System from Advanced Analytical.

SLAS2018 Hotels Now Accepting Reservations
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SLAS has secured discount rates at the Marriott Marquis San Diego Marina and Hilton San Diego Bayfront for attendees of SLAS2018, Feb. 3-7. Both hotels are adjacent to the San Diego Convention Center (where SLAS2018 is held).

The Marriott rate is $273/night plus taxes; the Hilton is $272/night plus taxes. Rates include free guest room Internet. Visit the SLAS2018 website for links to hotel reservation pages and other travel information. Act soon as official hotels fill up fast.

Four SLAS Professional Team Members Energized after Conference Participation
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SLAS CEO Vicki Loise, Director of Marketing Communications Tom Manning and Senior Manager of Events and Education Amy Wilkinson participated in the American Society of Association Executives (ASAE) Annual Meeting & Exposition in Toronto while Director of Publishing Nan Hallock participated in the International Society of Managing and Technical Editors (ISMTE) North American Conference in Denver. They learned new trends and best practices from education sessions, current and potential service providers and other professionals. Loise presented, "Not Just for the Kitchen: Building Your Professional Cabinet."

"I have found surrounding myself with other association professionals who I can rely upon as resources and share information with to be a game changer on the road to being successful as a CEO," Loise shares. "I always learn something when I get the chance to spend time with smart people."



Synthesis and Exciton Dynamics of Donor-Orthogonal Acceptor Conjugated Polymers: Reducing the Singlet—Triplet Energy Gap
Journal of the American Chemical Society    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The presence of energetically low-lying triplet states is a hallmark of organic semiconductors. Even though they present a wealth of interesting photophysical properties, these optically dark states significantly limit optoelectronic device performance. Recent advances in emissive charge-transfer molecules have pioneered routes to reduce the energy gap between triplets and "bright" singlets, allowing thermal population exchange between them and eliminating a significant loss channel in devices. More

The Vital Role of Emerging Gene Transfer Methods in T-cell Cancer Therapy
Bioscience Technology    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Cancer is one of the leading causes of death worldwide, with new cases expected to rise by 70 percent over the next two decades, making the search for an effective treatment more important now than ever before. Great strides have been made in recent years in the form of cancer immunotherapies. Inspired by discoveries about how the immune system works, immunotherapies are designed to reinforce the immune system’s ability to recognize and eliminate cancer cells. More

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'Twinkling' Enzymes Could Light the Way to Better Cancer Drugs    Share    Share on FacebookTwitterShare on LinkedinE-mail article
A new test to show the properties of biologically important enzymes could help to streamline development of new treatments. "Twinkle, twinkle, little kinase. How I wonder what form you are ..." It may not make for the best nursery rhyme, but an approach that sees proteins "twinkle" like stars in the night sky is providing new insight into an important class of enzymes involved in disease. More

Researchers Discover Fundamental Pathology behind ALS
Lab Manager    Share    Share on FacebookTwitterShare on LinkedinE-mail article
A team led by scientists at St. Jude Children's Research Hospital and Mayo Clinic has identified a basic biological mechanism that kills neurons in amyotrophic lateral sclerosis (ALS) and in a related genetic disorder, frontotemporal dementia (FTD), found in some ALS patients. ALS is popularly known as Lou Gehrig disease. The researchers were led by J. Paul Taylor, MD, PhD, chair of the St. Jude Cell and Molecular Biology Department and a Howard Hughes Medical Institute investigator; and Rosa Rademakers, PhD, of the Mayo Clinic in Jacksonville, Florida. More

KMC Systems Engineering & Manufacturing

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Study: Vaccine Blocks Psychostimulant Drug in Mice
The Scientist    Share    Share on FacebookTwitterShare on LinkedinE-mail article
In a report published in Nature, researchers uncover the mechanisms by which the psychoactive and addictive drug fenethylline, trade name Captagon, exerts its potent stimulating effects. Essentially, one component of the drug, theophylline, boosts the effects of another, amphetamine. "This combination greatly enhances amphetamine's properties," says coauthor and Scripps Research Institute researcher Kim Janda in a press conference, Reuters reports. "So this now makes sense why it's being so heavily abused." More

Triplet Diradical Cyclobutadiene Spotted for the First Time
Chemical & Engineering News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Carbon and silicon are both group 14 elements. That's supposed to mean that the two elements share many chemical properties. They do, yet the properties of their low-coordinate compounds are dramatically different: For example, although C=C bonds are ubiquitous, Si=C and Si=Si bonds are rare, and the latter can be isolated only when sterically protected by large substituents. Those bonding differences stem from a number of parameters, including electronegativity differences, the size and energies of the elements' s and p bonding orbitals, and bond energies, according to Yitzhak Apeloig of Technion—Israel Institute of Technology. More

FDA Approves First Fixed-Dose Combo Treatment for Hyperuricemia in Gout
Genetic Engineering & Biotechnology News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The FDA has approved the first fixed-dose combination treatment designed to address in a single pill both causes of hyperuricemia in gout—overproduction and underexcretion of serum uric acid. Ironwood Pharmaceuticals will market Duzallo® (lesinurad and allopurinol), which is indicated as a once-daily oral treatment for hyperuricemia associated with gout in patients who have not achieved target serum uric acid (sUA) levels with a medically appropriate daily dose of allopurinol alone. More

AI Implications: Engineer's Model Lays Groundwork for Machine-Learning Device
Science Daily    Share    Share on FacebookTwitterShare on LinkedinE-mail article
In what could be a small step for science potentially leading to a breakthrough, an engineer at Washington University in St. Louis has taken steps toward using nanocrystal networks for artificial intelligence applications. Elijah Thimsen, assistant professor of energy, environmental & chemical engineering in the School of Engineering & Applied Science, and his collaborators have developed a model in which to test existing theories about how electrons move through nanomaterials. More


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