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  Mobile version   RSS   Subscribe   Unsubscribe   Archive   Media Kit Aug. 28, 2013    SLAS2014    Moving? New job? Let SLAS know.    






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SLAS announces opening of Brussels office
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SLAS President Jeff Paslay says the new SLAS office in Brussels, Belgium, offers the SLAS community in Europe more convenient access to the many valuable benefits of SLAS membership. The Europe professional team, along with the teams in the SLAS Asia office in Shanghai, China, and the SLAS global headquarters in suburban Chicago, Illinois, positions SLAS to interact more closely with the laboratory science and technology community worldwide. Read more in Paslay’s latest column in the SLAS Electronic Laboratory Neighborhood e-zine. More


Phenotypic drug discovery webinar series launches next month
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David C. Swinney, Ph.D., Institute for Rare and Neglected Diseases Drug Discovery, kicks off the three-part SLAS webinar series on Sept. 26 with “The Value of Phenotypic-Based Drug Discovery.” In his webinar presentation, Swinney will discuss the challenges and solutions to assimilating molecular and phenotypic approaches to increase drug discovery success. The webinar is free to dues-paid SLAS members and sponsored by Cellular Dynamics International. Coming in December: the first of a two-part special issue of JBS on phenotypic drug discovery featuring new, original research by Swinney et al. More

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JALA Online features new manuscripts ahead-of-print
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"Modeling Mass Transfer from Carmustine-Loaded Polymeric Implants for Malignant Gliomas," "A Rapid Automatic Processing Platform for Bead Label–Assisted Microarray Analysis: Application for Genetic Hearing-Loss Mutation Detection" and "Capture and Exploration of Sample Quality Data to Inform and Improve the Management of a Screening Collection" are among the new manuscripts available only to SLAS Laboratory Automation Section members and JALA subscribers ahead-of-print. More

SLAS2014 short courses offer targeted training
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Seventeen unique one- or two-day comprehensive reviews of popular topics of interest to the laboratory science and technology community will be offered Saturday and Sunday, Jan. 18 and 19, to help kick-off SLAS2014 in San Diego. Select course titles include: "Automation for in vitro Diagnostics," "LIMS in the Organization," "Next Generation Sequencing Technology Fundamentals and Application" and "Microfluidics I/II." Courses, led by practicing professionals and recognized subject matter experts, are a time- and cost-efficient means of maximizing SLAS conference participation. More


ELRIG Drug Discovery 2013 presented in collaboration with SLAS
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Participants at the European Laboratory Robotics Interest Group Drug Discovery conference, Sept. 3-4, Manchester, U.K., will find two sessions presented by SLAS:
  • An in vitro Assay Development and High Throughput Screen identified Monocyclic Beta-lactams as mechanism-based Inhibitors of Rhomboid Intramembrane Protease" by O. Pierrat (France)
  • The Potential of Microfluidics to Improve in vitro Technologies for Drug Discovery by S. Verpoorte (The Netherlands)
The ELRIG event focuses on innovations and advances in basic and translational aspects of drug discovery in eight scientific sessions: Target & Biomarker Identification & Validation; Advanced Cell Technologies; In Vitro DMPK & Safety Screening; Macromolecules as Therapeutics; Innovations In Assay Development & Screening; Science Led Sample Management; Oncology Drug Targets; and Macromolecules as Tools for Discovery & Target Validation. Registration is free.

Facebook friend celebrates scientists
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Virginia Kepner made the following post after exploring the stories of SLAS innovators on the SLAS Electronic Laboratory Neighborhood e-zine Facebook page: "The world must learn to appreciate scientists more. All their knowledge and all their efforts in their conquering of amazing science! In their never-ending achievements that relieve us of the burdens of the past! With cures that have saved so many, and so many more to come! Thank you, to all the scientists of the world, for making it a better horizon, for us all. Keep up the GREAT work and pride of such talent and expertise! We love you." More

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Seven innovators over 70
MIT Technology Review    Share    Share on FacebookTwitterShare on LinkedinE-mail article
For over a decade, we've celebrated innovators under the age of 35. We choose to write about the young because we want to introduce you to the most promising new technologists, researchers and entrepreneurs. But I often hear: You really think older people can't innovate? Of course they can. We meet extraordinary older innovators all the time, who after a lifetime of creativity are still solving big problems, generating wealth or expanding our conception of what it means to be human. More

'Lung on a chip' tech set to revolutionize scientific drug testing
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Cutting-edge "lung on a chip" technology is poised to revolutionize the way scientists test new drugs. The first-of-its kind device may be a faster, cheaper way to develop drugs and avoid the need to perform testing on animals. The technology, as Dr. Donald Ingber, lead researcher and director of the Wyss Institute for Biologically Inspired Engineering at Harvard, showed on "CBS This Morning," is a clear polymer chip that mimics the organ's function, as it is lined with living human cells inside hollow channels. More


Sulfonium polymers deliver DNA into human cells
Chemical & Engineering News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Introducing therapeutic nucleic acids into cells is a way to potentially fix the genetic causes of diseases such as Down's syndrome and cystic fibrosis. Scientists have designed synthetic materials to deliver nucleic acids into cells, focusing mainly on nitrogen-based polymers. Now polymer chemists report a sulfonium-based macromolecule that can package DNA and slip into human cells. More

A license to infringe on research tool patents
Genetic Engineering & Biotechnology News    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Biopharmaceutical executives and lawyers have often viewed the Hatch-Waxman safe harbor exemption and patent term extension provisions in tandem: Infringers obtain the protection of the safe harbor, while patentees take advantage of the patent term extension provisions. While this may be logical and understandable, it is incorrect. There is no legal nexus between these two portions of the Hatch-Waxman Act. Furthermore, several recent decisions make clear that in many more instances than previously thought, the safe harbor will apply to patents whose terms are not extendable. More


The benefits, limits of DNA sequencing
The Boston Globe    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Jeanne and Andy Nadeau had one gnawing question about their large family: Would the hearing loss that affects half of their busy, boisterous household of 10 children worsen as the children grew older? The Nadeaus could prepare for the future if they knew whether the children who whisper in shouting voices and sleep soundly through violent thunderstorms would eventually become deaf or develop other health issues. More

New device cuts time to ID bacterial infections
LiveScience    Share    Share on FacebookTwitterShare on LinkedinE-mail article
A new device can rapidly identify nearly 200 different types of bacteria and yeast known to cause disease in people. The device, called VITEK MS, is able to identify which particular species of bacteria or yeast is causing an infection in a patient much more quickly than traditional methods that hospital laboratories use, the researchers said. More

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Dr. Francis Collins of NIH sings the 'Sequester Blues'
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The head of the National Institutes of Health sent a congratulatory message to the winner of the $100,000 Lurie Prize by video — including this song, lamenting the impacts of the budget sequester on the agency and government-funded science. More

And the genomes keep shrinking ...
National Geographic    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Here are a few numbers about DNA–some big ones, and then some very small ones. The human genome contains about 3.2 billion base pairs. Last year, scientists at the University of Leceister printed the sequence out in 130 massive reference-book-sized volumes for a museum exhibit. From start to finish, they would take nearly a century to read. More


Scientists pinpoint 105 additional genetic errors that cause cystic fibrosis
Bioscience Technology    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Of the over 1,900 errors already reported in the gene responsible for cystic fibrosis, it is unclear how many of them actually contribute to the inherited disease. Now a team of researchers reports significant headway in figuring out which mutations are benign and which are deleterious. In so doing, they have increased the number of known CF-causing mutations from 22 to 127, accounting for 95 percent of the variations found in patients with CF. More

Physicist disentangles 'Schrodinger's cat' debate    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Physicist Art Hobson has offered a solution, within the framework of standard quantum physics, to the long-running debate about the nature of quantum measurement. In an article published Aug. 8 by Physical Review A, a journal of the American Physical Society, Hobson argues that the phenomenon known as "nonlocality" is key to understanding the measurement problem illustrated by "Schrodinger's cat." More

Enabling enhanced emission and low-threshold lasing of organic molecules using special Fano resonances of macroscopic photonic crystals
Proceedings of the National Academy of Sciences    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The nature of light interaction with matter can be dramatically altered in optical cavities, often inducing nonclassical behavior. In solid-state systems, excitons need to be spatially incorporated within nanostructured cavities to achieve such behavior. Although fascinating phenomena have been observed with inorganic nanostructures, the incorporation of organic molecules into the typically inorganic cavity is more challenging. More

Structure of chromosomes supported by a kind of molecular skeleton
Science Daily    Share    Share on FacebookTwitterShare on LinkedinE-mail article
Jan-Michael Peters and his team at the Research Institute of Molecular Pathology found that the structure of chromosomes is supported by a kind of molecular skeleton, made of cohesin. Their discovery is published online in the current issue of the journal Nature. Every single cell in the human body contains an entire copy of the genetic blueprint, the DNA. Its total length is about 3.5 meters and all of it has to fit into the cell's nucleus, just one-hundredth of a millimeter in diameter. More

BMG LABTECH Introduces The CLARIOstar
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Senior Scientist Compound Management
UK – Cheshire – Alderley Park

Neural Mechanisms of Drug Addiction – Postdoctoral Fellow
The University of Texas Southwestern Medical Center
US – TX – Dallas

Faculty Physiology/Pharmacology
Des Moines University
US – IA – Des Moines

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