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Early experiences with Dynaflow at ELRIG
SLAS Share
   
Gary Clark, BioFocus, will discuss a microfluidics-based multichannel automated electrophysiology platform at the SLAS session at ELRIG Drug Discovery 2011, Sept. 7-8, Manchester Central, U.K.
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Conversion of mouse and human fibroblasts into functional spinal motor neurons
SLAS Share
A team of Harvard stem cell researchers, including September SLAS Screening Stem Cells 2011 speaker Kevin Eggan, has
succeeded in reprogramming adult mouse skin cells directly into the type of motor neurons damaged in ALS. Learn about this discovery in a Cell Stem Cell article.
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Get results fast
with Hamamatsu’s FDSS µCELL, an imaging-based microplate reader. This affordable, simple-to-use reader accommodates 96- or 384-well microplates for kinetic cell-based assays such as GPCR, ion channel, prolyl isomerase, transporter, and light-activated receptor or channel assays. Click here for more info.
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Twelve posters selected for SLAS Screening Stem Cells 2011
SLAS Share
Poster presenters from Turkey, Israel and the U.S. cover a broad range of topics to supplement the scientific sessions and exhibits at SLAS Screening Stem Cells 2011, Sept. 26-27, Boston. Register today.
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SLAS ELN feature: Ion channel biologists making great strides
SLAS Share
Advanced technology is propelling more effective investigations – and helping move things more quickly through the drug discovery
pipeline. Read this latest feature in SLAS Electronic Laboratory Neighborhood.
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Have you visited the SLAS video channel recently?
SLAS Share
Enthusiasts share SLAS moments on the SLAS video channel on YouTube.com, including one featuring the FIRST (For Inspiration and Recognition of Science and Technology) students from LabAutomation2011. SLAS will once again showcase FIRST at SLAS2012.
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The Access™ laboratory workstation transforms any Echo® liquid handler into an automated system for gene expression assays with reaction volumes as low as 250 nL. MORE |
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SRU Biosystems has
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Ultra Low Attachment Surface plates feature a covalently bound hydrogel layer that effectively inhibits cellular attachment, minimizes protein absorption, enzyme activation, and cellular activation. Corning® introduces 384 well black clear bottom Ultra Low Attachment Surface plates for HTS applications of tumor spheroid and stem cell embryoid body screening.
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Transform uHT Screening: Replace microplates with Nexar’s in-line sample processing in Array Tape - a continuous plastic strip, serially embossed with reaction wells
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In spirited research, chemists use brand-name liquors as solvents for organic syntheses
Chemical &
Engineering News Share
In a fit of whimsy, a research group at Northern Arizona University has taken a crack at using commercial brands of distilled alcohols as solvents to carry out common organic
syntheses. Besides being a bit fun and helping draw the chemical interest of undergraduate students, the research has the practical aspect of using ethanol as a green solvent to replace halogenated and other types of petroleum-derived solvents that are toxic and environmentally problematic.
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T-cell discovery holds promise for organ transplant, immunodeficiency treatment
eBio News Share
University of British Columbia researchers have solved a long-standing mystery surrounding the activation of T-cells, white blood cells that find and kill viruses and bacteria but also
participate in the rejection of transplanted organs. By identifying the mechanism that leads T-cells to spring into action and proliferate, the research, published online this month by the journal Immunity, provides a new target for future or existing drugs that could bolster the immune systems of people with HIV or cancer, according to lead researcher Wilfred Jefferies, professor in the Michael Smith Laboratories.
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Nature Middle East is a FREE resource for scientists and clinicians to connect, research, network and exchange information and ideas. Sign up to the latest research coming out of the Arab world and become part of the of Nature Middle East community.
You can also follow Nature Middle East on Facebook and Twitter. |
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Panda poop may be a treasure trove of microbes for making biofuels
PhysOrg Share
Panda poop contains bacteria with potent effects in breaking down plant material in the way needed to tap biomass as a major new source of "biofuels" produced not from corn and other food sources, but from grass, wood chips and crop wastes, scientists reported today at the 242nd National Meeting & Exposition of the American Chemical Society (ACS).
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Climate change and extreme hydrology
National Academy of Sciences Share
A "grand challenge" to understand the manifestation of change in floods and droughts faces climate and water science researchers, says a new report from the National Research Council based on proceedings from a workshop. A coherent picture of how these phenomena will shift due to changes in climate and land use has yet to emerge, but better understanding could be achieved through greater exchange of research
findings among climate scientists, water scientists, and engineers.
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Single-molecule resolution of organometallic intermediate in surface-supported Ullmann coupling reaction
Journal of the American Chemical Society Share
We have studied the organometallic intermediate of a surface-supported Ullmann coupling reaction from 4, 4″-dibromo-p-terphenyl to poly(para-phenylene) by scanning tunneling microscopy/spectroscopy and density functional theory calculations. Our study reveals at a single-molecular level that the intermediate consists of biradical terphenyl
(ph)3 units that are connected by single Cu atoms through C–Cu–C bridges. Upon further increasing the temperature, the neighboring biradical (ph)3 units are coupled by C–C bonds forming poly(para-phenylene) oligomers while the Cu atoms are released.
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Direct cetection of biologically significant thiols, disulfides with manganese(IV) chemiluminescence
Analytical Chemistry Share
The quantification of low-molecular mass thiols and disulfides involved in cellular redox processes is hindered by oxidation or degradation of
analytes during conventional sample preparation steps (including deproteinization and derivatization). Researchers therefore seek techniques that minimize sample handling and permit direct detection of thiols and disulfides within a single chromatographic separation. We demonstrate a new HPLC procedure for these biologically important analytes that incorporates direct chemiluminescence detection with a manganese(IV) reagent.
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Results from Large Hadron Collider don't look good for Supersymmetry Theory
Popular Science Share
The latest news from the Large Hadron Collider: scientists still cannot explain why we're all here. In the most detailed analysis of strange beauty particles — that's what
they're really called — physicists cannot find supersymmetric particles, which are shadow partners for every known particle in the standard model of modern physics. This could mean that they don't exist, which would be very interesting news indeed.
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Sensor chip for monitoring tumors
Science Daily Share
A chip implant may soon be capable of monitoring tumors that are difficult to operate on or growing slowly. Medical engineers at Technische Universitaet Muenchen (TUM) have developed
an electronic sensor chip that can determine the oxygen content in a patient's tissue fluid. This data can then be wirelessly transmitted to the patient's doctor to support the choice of therapy. A drop in oxygen content in tissue surrounding a tumor indicates that the tumor might be growing faster and becoming aggressive.
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The Sci-Print MP2+ is a high throughput fully automated barcode printer for labeling microtiter plates and deep well blocks. Stacks can hold 50 microtiter plates and can label any or all sides of the plate. User configurable label text with multiple barcode formats. Click here to see product videos and more!
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The HTFC® Screening System from IntelliCyt is a fast, highly sensitive, and simple-to-operate multicolor platform for phenotypic screening. This automation-friendly system can analyze thousands of cells per second from 96 or 384 well microplates and create heatmap data displays to quickly visualize hits.
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Venenum BioDesign specializes in HTS of 5.5 million compounds including new libraries for protein-protein interactions.
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A collaborative compilation of the world's laboratory technology knowledge grown and updated by an online community.
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The SLAS Innovation Award recognizes the work behind that one unique and special presentation at SLAS2012.
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