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  Mobile version   RSS   Subscribe   Unsubscribe    SLAS2012   Moving? New job? Let SLAS know.    Aug. 31, 2011



Early experiences with Dynaflow at ELRIG
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Gary Clark, BioFocus, will discuss a microfluidics-based multichannel automated electrophysiology platform at the SLAS session at ELRIG Drug Discovery 2011, Sept. 7-8, Manchester Central, U.K. More


Conversion of mouse and human fibroblasts into functional spinal motor neurons
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A team of Harvard stem cell researchers, including September SLAS Screening Stem Cells 2011 speaker Kevin Eggan, has succeeded in reprogramming adult mouse skin cells directly into the type of motor neurons damaged in ALS. Learn about this discovery in a Cell Stem Cell article. More

Add-and-Read Plate Reader
Get results fast with Hamamatsu’s FDSS µCELL, an imaging-based microplate reader. This affordable, simple-to-use reader accommodates 96- or 384-well microplates for kinetic cell-based assays such as GPCR, ion channel, prolyl isomerase, transporter, and light-activated receptor or channel assays. Click here for more info.

Twelve posters selected for SLAS Screening Stem Cells 2011
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Poster presenters from Turkey, Israel and the U.S. cover a broad range of topics to supplement the scientific sessions and exhibits at SLAS Screening Stem Cells 2011, Sept. 26-27, Boston. Register today. More


SLAS ELN feature: Ion channel biologists making great strides
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Advanced technology is propelling more effective investigations – and helping move things more quickly through the drug discovery pipeline. Read this latest feature in SLAS Electronic Laboratory Neighborhood. More

Have you visited the SLAS video channel recently?
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Enthusiasts share SLAS moments on the SLAS video channel on, including one featuring the FIRST (For Inspiration and Recognition of Science and Technology) students from LabAutomation2011. SLAS will once again showcase FIRST at SLAS2012. More

Miniaturize Gene Expression

The Access™ laboratory workstation transforms any Echo® liquid handler into an automated system for gene expression assays with reaction volumes as low as 250 nL.
Introducing the BIND® SCANNER from SRU Biosystems
SRU Biosystems has introduced the first and only high resolution, optical, label-free plate reader. Capable of measuring functional responses in individual cells, the SCANNER represents a new paradigm in drug discovery enabling the use of primary cells earlier in drug discovery process. Contact us to learn more.
Ultra Low Attachment Surface in HTS
Ultra Low Attachment Surface plates feature a covalently bound hydrogel layer that effectively inhibits cellular attachment, minimizes protein absorption, enzyme activation, and cellular activation. Corning® introduces 384 well black clear bottom Ultra Low Attachment Surface plates for HTS applications of tumor spheroid and stem cell embryoid body screening.
Nexar® In-line
Liquid Handler
Transform uHT Screening: Replace microplates with Nexar’s in-line sample processing in Array Tape - a continuous plastic strip, serially embossed with reaction wells
Increase Throughput: Efficient, parallel processing within customized modules
Save Reagents: Accurate, nanoliter dispense into miniaturized reaction
wells (1µL)
Simplify Workflow: Process integration without robotic or manual microplate handling MORE


In spirited research, chemists use brand-name liquors as solvents for organic syntheses
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In a fit of whimsy, a research group at Northern Arizona University has taken a crack at using commercial brands of distilled alcohols as solvents to carry out common organic syntheses. Besides being a bit fun and helping draw the chemical interest of undergraduate students, the research has the practical aspect of using ethanol as a green solvent to replace halogenated and other types of petroleum-derived solvents that are toxic and environmentally problematic. More


T-cell discovery holds promise for organ transplant, immunodeficiency treatment
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University of British Columbia researchers have solved a long-standing mystery surrounding the activation of T-cells, white blood cells that find and kill viruses and bacteria but also participate in the rejection of transplanted organs. By identifying the mechanism that leads T-cells to spring into action and proliferate, the research, published online this month by the journal Immunity, provides a new target for future or existing drugs that could bolster the immune systems of people with HIV or cancer, according to lead researcher Wilfred Jefferies, professor in the Michael Smith Laboratories. More


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Panda poop may be a treasure trove of microbes for making biofuels
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Panda poop contains bacteria with potent effects in breaking down plant material in the way needed to tap biomass as a major new source of "biofuels" produced not from corn and other food sources, but from grass, wood chips and crop wastes, scientists reported today at the 242nd National Meeting & Exposition of the American Chemical Society (ACS). More

Climate change and extreme hydrology
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A "grand challenge" to understand the manifestation of change in floods and droughts faces climate and water science researchers, says a new report from the National Research Council based on proceedings from a workshop. A coherent picture of how these phenomena will shift due to changes in climate and land use has yet to emerge, but better understanding could be achieved through greater exchange of research findings among climate scientists, water scientists, and engineers. More


Single-molecule resolution of organometallic intermediate in surface-supported Ullmann coupling reaction
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We have studied the organometallic intermediate of a surface-supported Ullmann coupling reaction from 4, 4″-dibromo-p-terphenyl to poly(para-phenylene) by scanning tunneling microscopy/spectroscopy and density functional theory calculations. Our study reveals at a single-molecular level that the intermediate consists of biradical terphenyl (ph)3 units that are connected by single Cu atoms through C–Cu–C bridges. Upon further increasing the temperature, the neighboring biradical (ph)3 units are coupled by C–C bonds forming poly(para-phenylene) oligomers while the Cu atoms are released. More

Direct cetection of biologically significant thiols, disulfides with manganese(IV) chemiluminescence
Analytical Chemistry    Share    Share on FacebookTwitterShare on LinkedinE-mail article
The quantification of low-molecular mass thiols and disulfides involved in cellular redox processes is hindered by oxidation or degradation of analytes during conventional sample preparation steps (including deproteinization and derivatization). Researchers therefore seek techniques that minimize sample handling and permit direct detection of thiols and disulfides within a single chromatographic separation. We demonstrate a new HPLC procedure for these biologically important analytes that incorporates direct chemiluminescence detection with a manganese(IV) reagent. More

Results from Large Hadron Collider don't look good for Supersymmetry Theory
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The latest news from the Large Hadron Collider: scientists still cannot explain why we're all here. In the most detailed analysis of strange beauty particles — that's what they're really called — physicists cannot find supersymmetric particles, which are shadow partners for every known particle in the standard model of modern physics. This could mean that they don't exist, which would be very interesting news indeed. More

Sensor chip for monitoring tumors
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A chip implant may soon be capable of monitoring tumors that are difficult to operate on or growing slowly. Medical engineers at Technische Universitaet Muenchen (TUM) have developed an electronic sensor chip that can determine the oxygen content in a patient's tissue fluid. This data can then be wirelessly transmitted to the patient's doctor to support the choice of therapy. A drop in oxygen content in tissue surrounding a tumor indicates that the tumor might be growing faster and becoming aggressive. More

Plate Label Applicator with Stacker

The Sci-Print MP2+ is a high throughput fully automated barcode printer for labeling microtiter plates and deep well blocks. Stacks can hold 50 microtiter plates and can label any or all sides of the plate. User configurable label text with multiple barcode formats. Click here to see product videos and more!
Automated Benchtop Cell Analysis Platform
The HTFC® Screening System from IntelliCyt is a fast, highly sensitive, and simple-to-operate multicolor platform for phenotypic screening. This automation-friendly system can analyze thousands of cells per second from 96 or 384 well microplates and create heatmap data displays to quickly visualize hits.
Sample Screening from your Compound
The comPOUND system comprises a high-density sample storage unit and an additional suite of specialized delivery and processing modules to enable easy integration into any compound management or screening system.


Quality Assurance Engineer Sr.
Watson Pharmaceuticals, Inc.
USA – CA – Corona

Research Associate Sr. II – Paper Binder Technology
BASF, The Chemical Company
USA – NC – Charlotte

Director, Microbiology & Environmental Control
Boehringer Ingelheim
USA – OH – Bedford

More jobs at SLAS Career Connections






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The Nexus Generation of Life Science Solutions

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Venenum BioDesign specializes in HTS of 5.5 million compounds including new libraries for protein-protein interactions.

An online scientific wiki

A collaborative compilation of the world's laboratory technology knowledge grown and updated by an online community.

SLAS awards $10,000 cash prize

The SLAS Innovation Award recognizes the work behind that one unique and special presentation at SLAS2012.

SLAS Point-to-Point
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