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Certified UPS’s to protect your laboratory’s critical instrumentation and resolve current and potential power issues.
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See how the Thermo Scientific Versette automated liquid handler can meet your liquid handling needs!
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Interactive e-zine sharing experiences and perspectives on science-related topics. Send article ideas to eln@slas.org.
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Boost your career or find the perfect candidate. SLAS Career Connections offers both online and in-person career services.
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 Enter to win a $500 Amazon gift card!
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Entries are now being accepted for the 2014 JALA & JBS Art of Science Contest. One grand prize winner will receive a $500 Amazon gift card. Nine finalists will receive $25 Amazon gift cards plus 60 days free online access to the SAGE Pharmacology and Biomedical Collection (75,000-plus articles!). Submit your favorite cell structures, assay results or other lab creations by Oct. 18. Read about last year's winners.
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The Lab Man: You Too Can Be a Molecular Biologist (or an Engineer, or a Programmer)
SLAS Share
The Lab Man explores the growing number of do-it-yourself technical operations giving individuals access to high-powered tools and expertise. In this latest entry, he features a Brooklyn, NY, artist who creates 3-D images of faces based on interpretation of collected DNA using a DIY biology lab. The Lab Man concludes: "The amazing thing is that such organizations make accessible tools, technology and expertise that one would have only found at very high-end facilities a decade ago. Access to the general public was out of the question."
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 SLAS now accepting proposals for JALA editor-in-chief position
SLAS Share
The editor-in-chief is the principal architect and arbiter of the Journal of Laboratory Automation’s scientific content, responsible for leading its strategic advancement in line with the SLAS mission and goals. Interested candidates should contact Nan Hallock, SLAS director of publishing, for more information about the role, responsibilities, qualifications, search plan and transition timelines.
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NEW! SLAS2014 Satellite Symposium announced
SLAS Share
SLAS and the Genomics Institute of the Novartis Research Foundation (GNF) are partnering for a Monday, Jan. 20, evening educational event in conjunction with SLAS2014 – Innovative Technologies for the Discovery of New Medicines. The symposium, free to SLAS2014 registered participants, includes scientific presentations by researchers and technologists affiliated with GNF, a tour of the facilities and a networking reception. Round-trip bus transportation is provided between GNF and the San Diego Convention Center. Event sponsors are Cisbio, Molecular Devices and Tecan. Attendance is limited and allocated on a first-come, first-served basis.
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 Journal of Laboratory Automation appoints Dino Di Carlo as Reviews Editor
SLAS Share
Congratulations to Dino Di Carlo, Ph.D., associate professor in the Department of Bioengineering at the University of California, Los Angeles. Di Carlo has contributed to JALA as an author and manuscript reviewer and has served as a member of the JALA Editorial Board since 2010. Di Carlo also has served SLAS many times as a conference speaker and is currently the Micro/Nano Technologies Track Chair for the SLAS2014 Program Committee.
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Journal of Biomolecular Screening GPCR manuscript featured in blog
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In the Pipeline blogger Derek Lowe cited the JBS title, Are GPCRs Still a Source of New Targets? by Stephen L. Garland of NQuiX in his blog post: GPCRs As Drug Targets: Nowhere Near Played Out. "Here's a paper that asks whether GPCRs are still a source of new targets. As you might guess, the answer is 'Yes, indeed.'"
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Dualsystems Biotech is a provider of custom proteomics services for industry and academia, specializing in ligand-receptor capture, affinity purification/mass spectrometry analysis of protein complexes and stable cell line generation.
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The xCELLigence RTCA Cardio System monitors cardiomyocyte beating functions in a 96-well format under physiological conditions, using a noninvasive label-free impedance-based technology. Rule out both acute and long-term cardiotoxicity in a single experiment. For more information, please visit www.aceabio.com.
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Get results fast with Hamamatsu’s FDSS µCELL, an imaging-based microplate reader. This affordable, simple-to-use reader accommodates 96- or 384-well microplates for kinetic cell-based assays such as GPCR, ion channel, prolyl isomerase, transporter, and light-activated receptor or channel assays. Click here for more info.
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Balancing act: Cell senescence, aging related to epigenetic changes
eBioNews Share
One way cells promote tumor suppression is through a process called senescence, an irreversible arrest of proliferation. Senescence is thought to be associated with normal aging, but is also a protective measure by the body against run-away cell replication. Studying the basic science of senescence gives biomedical researchers a better understanding of the mechanisms behind age-related diseases such as cancer.
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Complete protein characterization using top-down mass spectrometry and ultraviolet photodissociation
Journal of the American Chemical Society Share
The top-down approach to proteomics offers compelling advantages due to the potential to provide complete characterization of protein sequence and post-translational modifications. Here we describe the implementation of 193 nm ultraviolet photodissociation in an Orbitrap mass spectrometer for characterization of intact proteins.
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Chlorophyll harnessed for use in nanophotonic applications
Phys.org Share
Researchers from Aalto University and the University of Helsinki are developing nanostructures in which chlorophylls are bound to synthetic materials. Chlorophyll is a true gift of nature to photonics, as it absorbs the wavelengths of blue and red color from sunlight very efficiently. The research project utilizes chlorophyll extracted from green plants.
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Understanding anatase
Chemical & Engineering News Share
Titanium dioxide is the go-to material for a host of technological applications including self-cleaning glass, antifogging coatings, and ways to split water to make hydrogen fuel. To understand why TiO2 works well and possibly develop strategies to enhance its performance, researchers have now determined the first detailed mechanism of initial steps of oxidations catalyzed by TiO2's less common mineral phase, anatase — reactions central to many TiO2 applications.
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MacArthur increases 'genius grants' to $625,000
The Huffington Post Share
The MacArthur Foundation announced that it is increasing the value of its annual "genius grants" to $625,000. Previously, grants of $500,000 have been awarded in a secrecy-shrouded process to winners who work in fields including music, medicine, the arts and journalism. The foundation last increased the grant in 2000.
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Swift treatment halves early death risk in HIV babies
New Scientist Share
Time is of the essence. Giving HIV-positive infants prompt treatment halves their risk of dying early in childhood. The finding builds on results earlier this year showing that a baby and 14 adults were effectively "cured" by early treatment. In 2005, Mark Cotton of Stellenbosch University in Cape Town, South Africa, began a study of 377 South African infants aged 6 to 12 months.
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Whether your lab is manual, semi-automated or fully automated, FlexLink has flexible conveyor systems and solutions that fit perfectly where space is limited and close machine interface is required.
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Whoa! Scientists grow a brain in a dish
Popular Science Share
Researchers from the Institute of Molecular Biotechnology in Vienna, Austria, have grown a three-dimensional, self-organizing model of a developing human brain in the lab using stem cells. Besides just being cool (brains in petri dishes!), the system could be used to model neurological diseases in an actual human brain, rather than in an animal model that may not develop in exactly the same way.
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Cyclodextrins in analytical chemistry: Host-guest type molecular recognition
Analytical Chemistry Share
Cyclodextrins are utilized in many diverse fields of analytical chemistry, due to their propensity to form reversible inclusion complexes and recognize analytes selectively. This feature shows how these nanocavities can serve analysts in sample preparation, sensitivity and selectivity improvement, enantio-separation, creating single-molecule sensors, and automatizing DNA sequencing.
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DNA 'cages' may aid drug delivery
Science Daily Share
Nanoscale "cages" made from strands of DNA can encapsulate small-molecule drugs and release them in response to a specific stimulus, McGill University researchers report in a new study. The research, published online Sept. 1 in Nature Chemistry, marks a step toward the use of biological nanostructures to deliver drugs to diseased cells in patients. The findings could also open up new possibilities for designing DNA-based nanomaterials.
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Magnetic nanoparticles for drug delivery
By Dr. Afsaneh Motamed-Khorasani Share
 Targeted drug delivery is a major problem for the treatment of many diseases. Magnetic nanoparticles, or MNPs, can be considered as promising drug-delivery candidates due to their special properties. They can be handled easily by an external magnetic field and can be delivered by passive and active strategies. Furthermore, visualization has become easy in MRI scans due to the use of MNP. However, there are some drawbacks to the use of MNPs.
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Insight into measuring titration uncertainty
METTLER TOLEDO Share
In order to use the result of a chemical analysis for other purposes, its quality must be assessed. One important quality feature is the probability that the result coincides with the "true" value. It is obtained by the evaluation of the measurement uncertainty. Although fully detailed and available to perform unassisted, the calculation of measurement uncertainty can be a complex process. An Oct. 24 METTLER TOLEDO webinar, Evaluation of Measurement Uncertainty (MU) in Titration, guides you through the individual steps of this evaluation by using the example of sodium hydroxide (NaOH) titrant standardization with potassium hydrogen phthalate (KHP).
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International Conference on Pharmacology and Drug Development
National University of Singapore Share
Registered participants for this Dec. 9-11 conference presented by the Yong Loo Lin School of Medicine at the National University of Singapore are invited to submit abstracts for oral presentation by Oct. 31. Symposium speakers and poster presentations will be selected to address pharmacology and its impact on cancer, neuroscience, immunology, cardiovascular biology and more. Keynote speakers include Prof. Shuh Narumiya of Kyoto University, Japan, and Prof. Philip Moore of National University of Singapore.
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BMG LABTECH is releasing its newest instrument, the CLARIOstar, a high performance microplate reader with advanced monochromators, spectrometer, and filters. With this cutting-edge, hybrid technology, the CLARIOstar offers clear superiority with unparalleled flexibility and sensitivity.
Anything is possible with BMG LABTECH’s CLARIOstar. Any wavelength. Any bandwidth. Any assay.
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Introducing AusWasher MTP, a plate washer with residual volume < 0.01µl, enabling the highest specificity ELISA in 96, 384,1536 well plates with dramatically reduced number of wash steps. Centrifugation eliminates aspiration of wash buffer: no clogging, uniform buffer removal, no damage from physical contact with needles. Available standalone and OEM.
Info: Wolfgang Mann wmann@ausbio.de
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Selling technical products and services to the government is no easy feat, Technical Communities Inc. is here to help. Our government schedules provide you with access to federal government agencies requiring vendors to be on a GSA schedule for purchasing. For more information on effectively selling to the government, call us at 571 484-9626 or visit us at www.technicalcommunities.com.
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SLAS Point-to-Point
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